Effect of Retroviral Endostatin Gene Transfer on Subcutaneous and Intraperitoneal Growth of Murine Tumors

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

1997 • 4,504 citations

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

2000 • 2,632 citations

Hepatogastroenterology

2011 • 2,496 citations

Gene Transfer into Humans — Immunotherapy of Patients with Advanced Melanoma, Using Tumor-Infiltrating Lymphocytes Modified by Retroviral Gene Transduction

1990 • 1,307 citations

The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses

1996 • 728 citations

Expression of Angiogenesis-Related Genes and Progression of Human Ovarian Carcinomas in Nude Mice

1998 • 377 citations

Continuous release of endostatin from microencapsulated engineered cells for tumor therapy

2001 • 372 citations

Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus

1991 • 304 citations

Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene

1999 • 301 citations

High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors

2000 • 235 citations

Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases

2000 • 226 citations

Epithelial Cell Cultures From Normal Glandular Tissue of Mice 2

1974 • 214 citations

Liposomes complexed to plasmids encoding angiostatin and endostatin inhibit breast cancer in nude mice.

1999 • 179 citations

Pathogenesis of ascites tumor growth: angiogenesis, vascular remodeling, and stroma formation in the peritoneal lining.

1995 • 165 citations

Mouse endostatin inhibits the formation of lung and liver metastases.

1999 • 152 citations

Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases.

2000 • 149 citations

Evaluation of promoter strength for hepatic gene expression in vivo following adenovirus-mediated gene transfer.

1996 • 143 citations

Continuous administration of angiostatin inhibits accelerated growth of colorectal liver metastases after partial hepatectomy.

2000 • 141 citations

Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice.

2000 • 120 citations

Progress in antiangiogenic gene therapy of cancer

2000 • 111 citations

The Angiogenesis Inhibitor, Endostatin, Does Not Affect Murine Cutaneous Wound Healing

2000 • 108 citations

Multiple mRNA species for the precursor to an adenovirus-encoded glycoprotein: identification and structure of the signal sequence.

1980 • 98 citations

Antiangiogenic Gene Therapy for Cancer via Systemic Administration of Adenoviral Vectors Expressing Secretable Endostatin

2000 • 88 citations

The influence of angiogenesis research on management of patients with breast cancer

1995 • 73 citations

Effects of an antibody to vascular endothelial growth factor receptor-2 on survival, tumor vascularity, and apoptosis in a murine model of colon carcinomatosis

2001 • 68 citations

Soluble Flt-1 gene therapy for peritoneal metastases using HVJ-cationic liposomes

2000 • 61 citations

Clinical studies of angiogenesis inhibitors: The university of texas md anderson center trial of human endostatin

2001 • 46 citations

Effect of angiogenesis inhibitor TNP-470 on the progression of human gastric cancer xenotransplanted into nude mice

1997 • 41 citations

Prevention of carcinomatosis and bloody malignant ascites in the rat by an inhibitor of angiogenesis

1984 • 38 citations

Combined suicide and cytokine gene therapy for peritoneal carcinomatosis

2000 • 25 citations

Antitumoral effect of interleukin-12-secreting fibroblasts in a mouse model of ovarian cancer: Implications for the use of ovarian cancer biopsy-derived fibroblasts as a vehicle for regional gene therapy

2000 • 16 citations

Angiogenesis inhibitor, TNP-470, suppresses growth of peritoneal disseminating foci.

2000 • 16 citations

Therapeutic effects of the angiogenesis inhibitor TNP-470 against carcinomatous peritonitis in mice

1995 • 11 citations

Premalignancy in vitro: progression of an initially benign epithelial cell line to malignancy.

1979 • 5 citations