Regulation of Tumor Angiogenesis by Organ-Specific Cytokines

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST.

1889 • 4,920 citations

Angiogenic Factors

1987 • 3,702 citations

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1994 • 3,367 citations

Tumor Angiogenesis: A New Significant and Independent Prognostic Indicator in Early-Stage Breast Carcinoma

1992 • 1,799 citations

The pathogenesis of cancer metastasis

1980 • 1,750 citations

Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma.

1993 • 1,646 citations

Control of Angiogenesis in Fibroblasts by p53 Regulation of Thrombospondin-1

1994 • 1,460 citations

Metastasis Results from Preexisting Variant Cells Within a Malignant Tumor

1977 • 1,422 citations

The role of angiogenesis in tumor growth.

1992 • 1,267 citations

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture.

1990 • 1,147 citations

The implications of angiogenesis for the biology and therapy of cancer metastasis

1994 • 1,120 citations

Interferon Alfa-2a Therapy for Life-Threatening Hemangiomas of Infancy

1992 • 1,076 citations

Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice.

1986 • 506 citations

Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses.

1987 • 491 citations

Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice.

1994 • 488 citations

Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas.

1995 • 442 citations

Fibroblast-mediated acceleration of human epithelial tumor growth in vivo.

1990 • 417 citations

Relation of vascular proliferation to tumor growth.

1976 • 413 citations

Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice.

1994 • 357 citations

Seed and Soil

1905 • 305 citations

Mechanisms of human tumor metastasis studied in patients with peritoneovenous shunts.

1984 • 301 citations

?Seed and soil? revisited: mechanisms of site-specific metastasis

1982 • 276 citations

Cancer invasion and metastasis : biologic and therapeutic aspects

1984 • 221 citations

Correlation of cell migration, cell invasion, receptor number, proteinase production, and basic fibroblast growth factor levels in endothelial cells.

1990 • 205 citations

Growth factor messenger RNA expression by human breast fibroblasts from benign and malignant lesions.

1991 • 204 citations

Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.

1994 • 190 citations

Downregulation of interleukin 8 gene expression in human fibroblasts: unique mechanism of transcriptional inhibition by interferon.

1992 • 184 citations

Human melanoma: Development and progression

1990 • 173 citations

Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells.

1994 • 145 citations

Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells.

1994 • 136 citations

Regulation of interleukin-8 expression in human melanoma cells by the organ environment.

1995 • 115 citations

Interferons and Collagen Production

1990 • 109 citations

Differential effects of interferon gamma and alpha on in vitro model of angiogenesis

1991 • 94 citations

Interferon-alpha and interleukin 2 synergistically enhance basic fibroblast growth factor synthesis and induce release, promoting endothelial cell growth.

1993 • 91 citations

Clinicopathological observations on metastasis in man studied in patients treated with peritoneovenous shunts.

1984 • 84 citations

Regulation of interleukin-8 production in a human colon epithelial cell line (HT-29)

1995 • 72 citations

Inhibition of wound healing in mice by local interferon alpha/beta injection.

1993 • 57 citations

Regulation of Gelatinase Production in Metastatic Renal Cell Carcinoma by Organ‐specific Fibroblasts

1994 • 50 citations

Lymphocyte-Induced Angiogenesis in Tumor-Bearing Mice

1976 • 48 citations

Angiogenesis: initiation and modulation.

1983 • 42 citations

The Significance of Hyperemia Around Tumor Implants.

1946 • 38 citations

Enhanced wound healing in animal models by interferon and an interferon inducer

1992 • 36 citations

In vitro modulation of the invasive and metastatic potentials of human renal cell carcinoma by interleukin-2 and/or interferon-alpha gene transfer

1994 • 34 citations

Leukocyte-induced Angiogenesis and Subcutaneous Growth of B16 Melanoma

1994 • 26 citations

Inducers and induction of interferons

1977 • 23 citations

Pathogenesis of an experimental model of Goodpasture's hemorrhagic pneumonitis.

1990 • 19 citations

Action of recombinant alpha interferon against experimental and spontaneous metastases in a murine model

1989 • 17 citations

Experimental Orthotopic Models of Organ-Specific Metastasis by Human Neoplasms

1994 • 13 citations

Host-tumor interactions in the progression of breast cancer metastasis.

1994 • 11 citations

Pathogenesis of an Experimental Model of Goodpasture's Haemorrhagic Pneumonitis

1990 • 10 citations

Scanning electron microscopic study of invasiveness between normal and neoplastic cells and fibroblasts in monolayer culture.

1988 • 6 citations