Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Mechanisms of angiogenesis

1997 • 5,696 citations

RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINS

1996 • 3,074 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1994 • 2,293 citations

Vasculogenesis

1995 • 1,344 citations

Definition of Two Angiogenic Pathways by Distinct α _v Integrins

1995 • 1,333 citations

Organ targeting In vivo using phage display peptide libraries

1996 • 1,198 citations

αv Integrins as receptors for tumor targeting by circulating ligands

1997 • 738 citations

Tumor interactions with the vasculature: angiogenesis and tumor metastasis

1990 • 598 citations

Vascular and interstitial barriers to delivery of therapeutic agents in tumors

1990 • 485 citations

Phage Libraries Displaying Cyclic Peptides with Different Ring Sizes: Ligand Specificities of the RGD-Directed Integrins

1995 • 472 citations

Angiogenesis, neovascular proliferation and vascular pathophysiology as targets for cancer therapy

1993 • 362 citations

Selection of peptides binding to the alpha 5 beta 1 integrin from phage display library.

1993 • 344 citations

Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor–type integrins inhibits retinal neovascularization

1996 • 336 citations

Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library

1994 • 308 citations

Endocytosis and recycling of the fibronectin receptor in CHO cells.

1989 • 231 citations

Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies.

1991 • 200 citations

Cytotoxic analogs of luteinizing hormone-releasing hormone containing doxorubicin or 2-pyrrolinodoxorubicin, a derivative 500-1000 times more potent.

1996 • 199 citations

[7] The use of carbodiimides in the preparation of immunizing conjugates

1980 • 197 citations

Fate of Bacteriophage Lambda in Non-immune Germ-free Mice

1973 • 183 citations

Immunohistochemical analysis of integrin αvβ3 expression on tumor‐associated vessels of human carcinomas

1997 • 167 citations

Cell binding and internalization by filamentous phage displaying a cyclic Arg-Gly-Asp-containing peptide.

1994 • 164 citations

Vascular targeting—a new approach to the therapy of solid tumors

1994 • 130 citations

Immunohistochemical analysis of integrin αvβ3 expression on tumor-associated vessels of human carcinomas

1997 • 130 citations

VEGF-mediated tumour angiogenesis: a new target for cancer therapy

1995 • 126 citations

Peptide Ligands for Integrin .alpha.v.beta.3 Selected from Random Phage Display Libraries

1995 • 123 citations

Angiogenesis: key principles, science, technology, medicine.

1992 • 71 citations

Penetration of Tumor Tissue by Antibodies and Other Immunoproteins

1991 • 54 citations

Angiogenesis

1992 • 5 citations

We need federal standards for managed care plans

1997 • 3 citations