Transcriptional regulation by the MAP kinase signaling cascades

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

The language of covalent histone modifications

2000 • 8,260 citations

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation

2001 • 3,295 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

Transcriptional Regulatory Networks in Saccharomyces cerevisiae

2002 • 2,967 citations

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

Transcriptional regulation by the phosphorylation-dependent factor CREB

2001 • 2,488 citations

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

1995 • 2,238 citations

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

1995 • 1,973 citations

Signal Transduction through MAP Kinase Cascades

1998 • 1,762 citations

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways

1996 • 1,519 citations

Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway

1995 • 1,453 citations

Gene silencing in mammals by small interfering RNAs

2002 • 1,403 citations

Selective interaction of JNK protein kinase isoforms with transcription factors.

1996 • 1,333 citations

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1993 • 1,313 citations

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1997 • 1,229 citations

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF

1999 • 1,068 citations

Inhibition of Adipogenesis Through MAP Kinase-Mediated Phosphorylation of PPARγ

1996 • 1,033 citations

The ETS-domain transcription factor family

2001 • 1,033 citations

A mechanism of repression of TGFbeta / Smad signaling by oncogenic Ras

1999 • 1,004 citations

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

1992 • 980 citations

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activationofCREB

1998 • 975 citations

Integration of MAP Kinase Signal Transduction Pathways at the Serum Response Element

1995 • 935 citations

Molecular interpretation of ERK signal duration by immediate early gene products

2002 • 914 citations

Serine phosphorylation of STATs

2000 • 873 citations

Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1

1997 • 867 citations

Protein chip technology

2003 • 866 citations

Synergistic Coupling of Histone H3 Phosphorylation and Acetylation in Response to Epidermal Growth Factor Stimulation

2000 • 782 citations

p42/p44 Mitogen-activated Protein Kinases Phosphorylate Hypoxia-inducible Factor 1α (HIF-1α) and Enhance the Transcriptional Activity of HIF-1

1999 • 777 citations

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

1997 • 770 citations

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

2003 • 742 citations

Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARγ Coactivator-1

2001 • 700 citations

The activities of two Ets-related transcription factors required for drosophila eye development are modulated by the Ras/MAPK pathway

1994 • 690 citations

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

1999 • 676 citations

Phosphorylation of the MAP Kinase ERK2 Promotes Its Homodimerization and Nuclear Translocation

1998 • 675 citations

FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2.

1996 • 633 citations

Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor

1998 • 618 citations

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

1999 • 602 citations

Progesterone Receptor Contains a Proline-Rich Motif that Directly Interacts with SH3 Domains and Activates c-Src Family Tyrosine Kinases

2001 • 582 citations

BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

1997 • 580 citations

Activation of ternary complex factor Elk-1 by MAP kinases.

1993 • 561 citations

MAPK Pathways Activate and Phosphorylate the Osteoblast-specific Transcription Factor, Cbfa1

2000 • 543 citations

Interdependent SMAD and JNK Signaling in Transforming Growth Factor-β-mediated Transcription

1999 • 534 citations

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1

2001 • 525 citations

Activation of the Protein Kinase ERK5/BMK1 by Receptor Tyrosine Kinases

1999 • 518 citations

c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi

2000 • 517 citations

A motif-based profile scanning approach for genome-wide prediction of signaling pathways

2001 • 517 citations

MAPKK-Independent Activation of p38α Mediated by TAB1-Dependent Autophosphorylation of p38α

2002 • 507 citations

c-Jun Can Recruit JNK to Phosphorylate Dimerization Partners via Specific Docking Interactions

1996 • 495 citations

Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase

1991 • 491 citations

Requirement of Rsk-2 for Epidermal Growth Factor-Activated Phosphorylation of Histone H3

1999 • 478 citations

Reduced Ubiquitin-Dependent Degradation of c-Jun After Phosphorylation by MAP Kinases

1997 • 462 citations

MSK1 and MSK2 Are Required for the Mitogen- and Stress-Induced Phosphorylation of CREB and ATF1 in Fibroblasts

2002 • 446 citations

Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome

2000 • 444 citations

The p38 Mitogen-activated Protein Kinase Is Required for NF-κB-dependent Gene Expression

1999 • 444 citations

AIB1 Is a Conduit for Kinase-Mediated Growth Factor Signaling to the Estrogen Receptor

2000 • 438 citations

Pharmacological inhibitors of MAPK pathways

2002 • 437 citations

Signal-dependent regulation of splicing via phosphorylation of Sam68

2002 • 432 citations

Docking domains and substrate-specificity determination for MAP kinases

2000 • 430 citations

Regulation of the MEF2 Family of Transcription Factors by p38

1999 • 429 citations

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

1999 • 427 citations

Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation

2000 • 415 citations

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

2002 • 412 citations

The N-CoR-HDAC3 Nuclear Receptor Corepressor Complex Inhibits the JNK Pathway through the Integral Subunit GPS2

2002 • 407 citations

MAPK-regulated transcription: a continuously variable gene switch?

2002 • 404 citations

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

1998 • 395 citations

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response

2002 • 381 citations

Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

1997 • 377 citations

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

1999 • 364 citations

Association of mitogen-activated protein kinase with the microtubule cytoskeleton.

1995 • 354 citations

ERKs and p38 Kinase Phosphorylate p53 Protein at Serine 15 in Response to UV Radiation

2000 • 347 citations

Nuclear Accumulation of NFAT4 Opposed by the JNK Signal Transduction Pathway

1997 • 347 citations

Hog1 Kinase Converts the Sko1-Cyc8-Tup1 Repressor Complex into an Activator that Recruits SAGA and SWI/SNF in Response to Osmotic Stress

2002 • 345 citations

Interdomain communication regulating ligand binding by PPAR-γ

1998 • 344 citations

MAPK Signaling Up-regulates the Activity of Hypoxia-inducible Factors by Its Effects on p300

2003 • 343 citations

JNK targets p53 ubiquitination and degradation in nonstressed cells

1998 • 339 citations

RETRACTED: Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade

2002 • 329 citations

Ras Pathway Specificity Is Determined by the Integration of Multiple Signal-Activated and Tissue-Restricted Transcription Factors

2000 • 324 citations

The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway

1994 • 315 citations

PEA-15 Mediates Cytoplasmic Sequestration of ERK MAP Kinase

2001 • 315 citations

Crystal Structures of MAP Kinase p38 Complexed to the Docking Sites on Its Nuclear Substrate MEF2A and Activator MKK3b

2002 • 309 citations

Identification of Two Sp1 Phosphorylation Sites for p42/p44 Mitogen-activated Protein Kinases

2002 • 293 citations

Raf induces TGFβ production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

2000 • 292 citations

Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase

1998 • 292 citations

Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases

1998 • 291 citations

ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation

2000 • 271 citations

Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor

2001 • 267 citations

ERK5 Is a Novel Type of Mitogen-Activated Protein Kinase Containing a Transcriptional Activation Domain

2000 • 263 citations

The Transcription Factor GATA4 Is Activated by Extracellular Signal-Regulated Kinase 1- and 2-Mediated Phosphorylation of Serine 105 in Cardiomyocytes

2001 • 261 citations

Phosphorylation of Steroid Receptor Coactivator-1

2000 • 260 citations

Analysis of the transcriptional program induced by Raf in epithelial cells

2001 • 255 citations

Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET).

1995 • 255 citations

A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity.

1993 • 253 citations

p38 Mitogen-activated Protein Kinase Activates Peroxisome Proliferator-activated Receptor α

2001 • 253 citations

Dynamic Interplay of the SUMO and ERK Pathways in Regulating Elk-1 Transcriptional Activity

2003 • 252 citations

Targeting of p38 Mitogen-Activated Protein Kinases to MEF2 Transcription Factors

1999 • 250 citations

Stress-Induced MAP Kinase Hog1 Is Part of Transcription Activation Complexes

2001 • 250 citations

ERK-Dependent Phosphorylation of the Transcription Initiation Factor TIF-IA Is Required for RNA Polymerase I Transcription and Cell Growth

2003 • 249 citations

Identification of Novel MAP Kinase Pathway Signaling Targets by Functional Proteomics and Mass Spectrometry

2000 • 246 citations

Transcription Control by E1A and MAP Kinase Pathway via Sur2 Mediator Subunit

2002 • 240 citations

An Immediate Response of Ribosomal Transcription to Growth Factor Stimulation in Mammals Is Mediated by ERK Phosphorylation of UBF

2001 • 240 citations

Microphthalmia Transcription Factor Is a Target of the p38 MAPK Pathway in Response to Receptor Activator of NF-κB Ligand Signaling

2002 • 238 citations

Activation of SRF-Regulated Chromosomal Templates by Rho-Family GTPases Requires a Signal that Also Induces H4 Hyperacetylation

1998 • 230 citations

c-Jun N-Terminal Kinase Phosphorylates Peroxisome Proliferator-Activated Receptor-γ1 and Negatively Regulates Its Transcriptional Activity

1999 • 228 citations

Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38

2002 • 226 citations

MAP kinase-mediated signalling to nucleosomes and immediate-early gene induction

1999 • 226 citations

The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression

2001 • 214 citations

A Network of Mitogen-Activated Protein Kinases Links G Protein-Coupled Receptors to the c-jun Promoter: a Role for c-Jun NH₂-Terminal Kinase, p38s, and Extracellular Signal-Regulated Kinase 5

1999 • 212 citations

Regulation of Estrogen Receptor Nuclear Export by Ligand-Induced and p38-Mediated Receptor Phosphorylation

2002 • 201 citations

Transcriptional Hyperactivity of Human Progesterone Receptors Is Coupled to Their Ligand-Dependent Down-Regulation by Mitogen-Activated Protein Kinase-Dependent Phosphorylation of Serine 294

2001 • 198 citations

Modulation of Smad2-mediated Signaling by Extracellular Signal-regulated Kinase

2002 • 194 citations

Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure.

1997 • 194 citations

Independent Dynamic Regulation of Histone Phosphorylation and Acetylation during Immediate-Early Gene Induction

2001 • 192 citations

Regulation of c-Myc through Phosphorylation at Ser-62 and Ser-71 by c-Jun N-Terminal Kinase

1999 • 185 citations

Docking Sites on Substrate Proteins Direct Extracellular Signal-regulated Kinase to Phosphorylate Specific Residues

2001 • 180 citations

Transcriptional Induction of MKP-1 in Response to Stress Is Associated with Histone H3 Phosphorylation-Acetylation

2001 • 175 citations

Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF

2001 • 174 citations

Phosphorylation of NFATc4 by p38 Mitogen-Activated Protein Kinases

2002 • 173 citations

An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors

2002 • 173 citations

Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer

2003 • 172 citations

MAPKAP Kinase 2 Phosphorylates Serum Response Factor in Vitro and in Vivo

1999 • 170 citations

Regulation of gene expression by the small GTPase Rho through the ERK6 (p38γ) MAP kinase pathway

2001 • 167 citations

C/EBPβ Phosphorylation by RSK Creates a Functional XEXD Caspase Inhibitory Box Critical for Cell Survival

2001 • 166 citations

MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300

2003 • 162 citations

Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1

1998 • 162 citations

Rapid Phosphorylation of Ets-2 Accompanies Mitogen-Activated Protein Kinase Activation and the Induction of Heparin-Binding Epidermal Growth Factor Gene Expression by Oncogenic Raf-1

1997 • 162 citations

Glycogen Synthase Kinase 3β and Extracellular Signal-Regulated Kinase Inactivate Heat Shock Transcription Factor 1 by Facilitating the Disappearance of Transcriptionally Active Granules after Heat Shock

1998 • 162 citations

The MEK Pathway Is Required for Stimulation of p21WAF1/CIP1 by Transforming Growth Factor-β

1999 • 160 citations

A Role for the p38 MAP Kinase Pathway in the Nuclear Shuttling of NFATp

2000 • 156 citations

MAP Kinases Erk1/2 Phosphorylate Sterol Regulatory Element-binding Protein (SREBP)-1a at Serine 117 in Vitro

2000 • 155 citations

Identification of Substrates and Regulators of the Mitogen-activated Protein Kinase ERK5 Using Chimeric Protein Kinases

1998 • 155 citations

The Extracellular Signal-Regulated Kinase Pathway Phosphorylates AML1, an Acute Myeloid Leukemia Gene Product, and Potentially Regulates Its Transactivation Ability

1996 • 153 citations

Growth Factors Signal to Steroid Receptors through Mitogen-activated Protein Kinase Regulation of p160 Coactivator Activity

2001 • 152 citations

Big Mitogen-activated Kinase Regulates Multiple Members of the MEF2 Protein Family

2000 • 152 citations

Intestinal Epithelial Cell Differentiation Involves Activation of p38 Mitogen-activated Protein Kinase That Regulates the Homeobox Transcription Factor CDX2

2001 • 151 citations

Phosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RARgamma degradation and transactivation

2002 • 151 citations

ERK1 and ERK2 Activate CCAAAT/Enhancer-binding Protein-β-dependent Gene Transcription in Response to Interferon-γ

2001 • 146 citations

c-Jun NH2-terminal Kinases Target the Ubiquitination of Their Associated Transcription Factors

1997 • 145 citations

Mitogen-activated Protein Kinase Phosphorylates and Negatively Regulates Basic Helix-Loop-Helix-PAS Transcription Factor BMAL1

2002 • 143 citations

Temporal Recruitment of the mSin3A-Histone Deacetylase Corepressor Complex to the ETS Domain Transcription Factor Elk-1

2001 • 141 citations

c-Jun NH2-terminal Kinase Targeting and Phosphorylation of Heat Shock Factor-1 Suppress Its Transcriptional Activity

2000 • 139 citations

In or out? Regulating nuclear transport

1999 • 137 citations

JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors

2002 • 133 citations

sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction.

1995 • 130 citations

c-Jun NH₂-Terminal Kinase Inhibits Targeting of the Protein Phosphatase Calcineurin to NFATc1

2000 • 130 citations

Interaction of Mitogen-activated Protein Kinases with the Kinase Interaction Motif of the Tyrosine Phosphatase PTP-SL Provides Substrate Specificity and Retains ERK2 in the Cytoplasm

1999 • 129 citations

Phosphorylation of Tristetraprolin, a Potential Zinc Finger Transcription Factor, by Mitogen Stimulation in Intact Cells and by Mitogen-activated Protein Kinase in Vitro

1995 • 129 citations

p38 Mitogen-activated Protein Kinase Mediates the Transcriptional Induction of the Atrial Natriuretic Factor Gene through a Serum Response Element

1998 • 128 citations

Intramolecular signal transduction in c-Jun.

1995 • 127 citations

Regulation of MAP kinases by docking domains

2001 • 127 citations

Transactivation of Fra-1 and Consequent Activation of AP-1 Occur Extracellular Signal-Regulated Kinase Dependently

2002 • 121 citations

Activated MEK1 Binds the Nuclear MyoD Transcriptional Complex to Repress Transactivation

2001 • 121 citations

Analysis of the ERK-Stimulated ETS Transcription Factor ER81

1996 • 121 citations

Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases

1999 • 121 citations

Histone deacetylase 4 associates with extracellular signal-regulated kinases 1 and 2, and its cellular localization is regulated by oncogenic Ras

2000 • 120 citations

Retinoic Acid Receptors Inhibit AP1 Activation by Regulating Extracellular Signal-Regulated Kinase and CBP Recruitment to an AP1-Responsive Promoter

2002 • 115 citations

Phosphorylation-Dependent Nucleocytoplasmic Shuttling of Pancreatic Duodenal Homeobox-1

2001 • 114 citations

The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1

1999 • 113 citations

Regulation of p73 by c-Abl through the p38 MAP kinase pathway

2002 • 109 citations

Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1)

2003 • 109 citations

Transcriptional Repressor ERF Is a Ras/Mitogen-Activated Protein Kinase Target That Regulates Cellular Proliferation

1999 • 103 citations

Regulation of GATA-2 Phosphorylation by Mitogen-activated Protein Kinase and Interleukin-3

1995 • 101 citations

Phosphorylation of the Transactivation Domain of Pax6 by Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinase

1999 • 100 citations

The Transcriptional Co-activators CBP and p300 Are Activated via Phenylephrine through the p42/p44 MAPK Cascade

2002 • 100 citations

Smad3 Mediates Transforming Growth Factor-β-induced Collagenase-3 (Matrix Metalloproteinase-13) Expression in Human Gingival Fibroblasts

2002 • 100 citations

ERKs and p38 Kinases Mediate Ultraviolet B-induced Phosphorylation of Histone H3 at Serine 10

2000 • 98 citations

Nerve Growth Factor Up-regulates the Transcriptional Activity of CBP through Activation of the p42/p44MAPK Cascade

1998 • 97 citations

Phosphorylation of MafA Is Essential for Its Transcriptional and Biological Properties

2001 • 93 citations

Complexities in ETS-Domain Transcription Factor Function and Regulation: Lessons from the TCF (Ternary Complex Factor) Subfamily

2002 • 93 citations

Selective Targeting of MAPKs to the ETS Domain Transcription Factor SAP-1

2001 • 91 citations

Interaction of p38 and Sp1 in a Mechanical Force-induced, β1 Integrin-mediated Transcriptional Circuit That Regulates the Actin-binding Protein Filamin-A

2002 • 91 citations

Regulation of the ETS Transcription Factor ER81 by the 90-kDa Ribosomal S6 Kinase 1 and Protein Kinase A

2002 • 89 citations

Hyperphosphorylation of the Retinoid X Receptor α by Activated c-Jun NH2-terminal Kinases

1999 • 85 citations

Interleukin-3 Stimulation of mcl-1 Gene Transcription Involves Activation of the PU.1 Transcription Factor through a p38 Mitogen-Activated Protein Kinase-Dependent Pathway

2003 • 82 citations

Drosophila Pin1 prolyl isomerase Dodo is a MAP kinase signal responder during oogenesis

2001 • 82 citations

Phosphorylation of Pax2 by the c-Jun N-terminal Kinase and Enhanced Pax2-dependent Transcription Activation

2002 • 80 citations

Rsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain

2001 • 80 citations

Persistent ERK Phosphorylation Negatively Regulates cAMP Response Element-binding Protein (CREB) Activity via Recruitment of CREB-binding Protein to pp90RSK

2003 • 79 citations

MSK1 and JNKs Mediate Phosphorylation of STAT3 in UVA-irradiated Mouse Epidermal JB6 Cells

2001 • 79 citations

Drosophila Fos mediates ERK and JNK signals via distinct phosphorylation sites

2001 • 74 citations

Phosphorylation of Transcriptional Coactivator Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein (PBP)

2002 • 73 citations

Serine/Threonine Kinases 3pK and MAPK-activated Protein Kinase 2 Interact with the Basic Helix-Loop-Helix Transcription Factor E47 and Repress Its Transcriptional Activity

2000 • 73 citations

CKA, a Novel Multidomain Protein, Regulates the JUN N-Terminal Kinase Signal Transduction Pathway in Drosophila

2002 • 71 citations

Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila

2001 • 68 citations

The Net Repressor Is Regulated by Nuclear Export in Response to Anisomycin, UV, and Heat Shock

1999 • 62 citations

Acetyllysine-binding and function of bromodomain-containing proteins in chromatin

2001 • 60 citations

Extracellular Signal-Regulated Kinase Binds to TFII-I and Regulates Its Activation of the c-fosPromoter

2000 • 59 citations

Stimulation of p300-mediated Transcription by the Kinase MEKK1

2001 • 57 citations

CBP associates with the p42/p44 MAPK enzymes and is phosphorylated following NGF treatment

1999 • 55 citations

The ternary complex factor Net contains two distinct elements that mediate different responses to MAP kinase signalling cascades

2000 • 54 citations

The Sevenless signaling pathway: variations of a common theme

2000 • 51 citations

Differential Gene Regulation by Specific Gain-of-function JNK1 Proteins Expressed in Swiss 3T3 Fibroblasts

2002 • 47 citations

c-Jun N-Terminal Kinase Phosphorylates Peroxisome Proliferator-Activated Receptor- 1 and Negatively Regulates Its Transcriptional Activity

1999 • 46 citations

Differential gene expression profiles of Jnk1- and Jnk2-deficient murine fibroblast cells.

2002 • 45 citations

Formation of an hERalpha-COUP-TFI complex enhances hERalpha AF-1 through Ser118 phosphorylation by MAPK

2002 • 43 citations

Cytokine-Responsive Induction of SAF-1 Activity Is Mediated by a Mitogen-Activated Protein Kinase Signaling Pathway

2002 • 37 citations

Histone H1S-3 phosphorylation in Ha-ras oncogene-transformed mouse fibroblasts

2002 • 34 citations

The Development and Use of Phospho-Specific Antibodies to Study Protein Phosphorylation

2003 • 33 citations

Differential targeting of the stress mitogen-activated protein kinases to the c-Jun dimerization protein 2

2002 • 31 citations

Activation of the mitogen-activated protein kinase pathway in U937 leukemic cells induces phosphorylation of the amino terminus of the TATA-binding protein.

1998 • 26 citations

Jun Kinase Phosphorylates and Regulates the DNA Binding Activity of an Octamer Binding Protein, T-Cell Factor β1

1999 • 20 citations

Regulation of Myeloid Zinc Finger Protein 2A Transactivation Activity through Phosphorylation by Mitogen-activated Protein Kinases

2003 • 13 citations