PEA-15 Mediates Cytoplasmic Sequestration of ERK MAP Kinase

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Mitogen-activated protein kinase pathways

1997 • 2,513 citations

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

1997 • 2,062 citations

Mammalian Ras interacts directly with the serine/threonine kinase raf

1993 • 1,983 citations

Signal Transduction through MAP Kinase Cascades

1998 • 1,762 citations

Short protocols in molecular biology

1996 • 1,701 citations

Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers

1999 • 1,593 citations

Integrins: Emerging Paradigms of Signal Transduction

1995 • 1,591 citations

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1997 • 1,195 citations

MAP kinase pathways

1999 • 875 citations

Leptomycin B Inhibition of Signal-Mediated Nuclear Export by Direct Binding to CRM1

1998 • 801 citations

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling

2000 • 796 citations

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

1997 • 654 citations

Complex formation between RAS and RAF and other protein kinases.

1993 • 633 citations

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

1999 • 602 citations

Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast

1995 • 578 citations

A Structural Basis for Substrate Specificities of Protein Ser/Thr Kinases: Primary Sequence Preference of Casein Kinases I and II, NIMA, Phosphorylase Kinase, Calmodulin-Dependent Kinase II, CDK5, and Erk1

1996 • 555 citations

Regulation of the Yeast HO Gene

1985 • 526 citations

Suppression of Integrin Activation: A Novel Function of a Ras/Raf-Initiated MAP Kinase Pathway

1997 • 501 citations

Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

1998 • 496 citations

MP1: A MEK Binding Partner That Enhances Enzymatic Activation of the MAP Kinase Cascade

1998 • 471 citations

A Comparison of the Activity, Sequence Specificity, and CRM1-Dependence of Different Nuclear Export Signals

2000 • 392 citations

MKP-3, a Novel Cytosolic Protein-tyrosine Phosphatase That Exemplifies a New Class of Mitogen-activated Protein Kinase Phosphatase

1996 • 350 citations

A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

1998 • 311 citations

Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1

1998 • 302 citations

Mitogen-activated protein kinases

2002 • 232 citations

Nuclear Export of Map Kinase (ERK) Involves a Map Kinase Kinase (Mek-Dependent) Active Transport Mechanism

2000 • 216 citations

Characterization of PEA-15, a major substrate for protein kinase C in astrocytes.

1993 • 165 citations

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

1999 • 164 citations

PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus

1998 • 160 citations

Knock-Out of the Neural Death Effector Domain Protein PEA-15 Demonstrates That Its Expression Protects Astrocytes from TNFα-Induced Apoptosis

1999 • 145 citations

Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion

1997 • 141 citations

Cellular Expression, Developmental Regulation, and Phylogenic Conservation of PEA‐15, the Astrocytic Major Phosphoprotein and Protein Kinase C Substrate

1995 • 108 citations

The Death Effector Domain of PEA-15 Is Involved in Its Regulation of Integrin Activation

1998 • 92 citations

Endothelin Induces a Calcium‐Dependent Phosphorylation of PEA‐15 in Intact Astrocytes: Identification of Ser¹⁰⁴ and Ser¹¹⁶ Phosphorylated, Respectively, by Protein Kinase C and Calcium/Calmodulin Kinase II In Vitro

1998 • 88 citations

Making sense of the multiple MAP-2 transcripts and their role in the neuron

1998 • 88 citations

Death Effector Domain Protein PEA-15 Potentiates Ras Activation of Extracellular Signal Receptor-activated Kinase by an Adhesion-independent Mechanism

2000 • 76 citations

The Major Astrocytic Phosphoprotein PEA-15 Is Encoded by Two mRNAs Conserved on Their Full Length in Mouse and Human

1996 • 71 citations

Hormonal regulation of mitogen-activated protein kinase activity in bovine adrenocortical cells: cross-talk between phosphoinositides, adenosine 3',5'-monophosphate, and tyrosine kinase receptor pathways.

1995 • 67 citations

Abundant nuclear ribonucleoprotein form of CAD RNA.

1985 • 52 citations

Novel Membrane-Targeted ERK1 and ERK2 Chimeras Which Act as Dominant Negative, Isotype-Specific Mitogen-Activated Protein Kinase Inhibitors of Ras-Raf-Mediated Transcriptional Activation of c-fos in NIH 3T3 Cells

1999 • 39 citations

Pleiotropic effects of lysophosphatidic acid on striatal astrocytes

1999 • 34 citations

Identification of a mammary transforming gene (MAT1) associated with mouse mammary carcinogenesis.

1994 • 33 citations

Abundant Nuclear Ribonucleoprotein Form of CAD RNA

1985 • 27 citations