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Crystal Structures of MAP Kinase p38 Complexed to the Docking Sites on Its Nuclear Substrate MEF2A and Activator MKK3b

Data up to Jan 2025

Published2002
Citations309
References41

Total Citations Per Year

Abstract

References (41)

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR

1996 • 5,190 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*

2001 • 3,897 citations

Signal Transduction through MAP Kinase Cascades

1998 • 1,762 citations

Selective interaction of JNK protein kinase isoforms with transcription factors.

1996 • 1,333 citations

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

1993 • 1,169 citations

Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

1990 • 1,087 citations

The Biochemical Basis of an All-or-None Cell Fate Switch in Xenopus Oocytes

1998 • 1,040 citations

Crystal structure of cyclin-dependent kinase 2

1993 • 946 citations

A conserved docking motif in MAP kinases common to substrates, activators and regulators

2000 • 801 citations

Further additions to MolScript version 1.4, including reading and contouring of electron-density maps

1999 • 763 citations

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.

1994 • 639 citations

Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution

1994 • 591 citations

The JIP Group of Mitogen-Activated Protein Kinase Scaffold Proteins

1999 • 454 citations

Docking domains and substrate-specificity determination for MAP kinases

2000 • 430 citations

Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1

1994 • 331 citations

PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif

1998 • 313 citations

Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1

1998 • 302 citations

Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions

2001 • 278 citations

The structure of mitogen-activated protein kinase p38 at 2.1-Å resolution

1997 • 272 citations

The Elk-1 ETS-Domain Transcription Factor Contains a Mitogen-Activated Protein Kinase Targeting Motif

1998 • 265 citations

An emerging family of dual specificity MAP kinase phosphatases

1995 • 256 citations

Targeting of p38 Mitogen-Activated Protein Kinases to MEF2 Transcription Factors

1999 • 250 citations

Molecular determinants that mediate selective activation of p38 MAP kinase isoforms

2000 • 219 citations

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

1998 • 201 citations

Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d

1998 • 200 citations

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis

1998 • 191 citations

Crystal structure of casein kinase-1, a phosphate-directed protein kinase.

1995 • 187 citations

A Conserved Docking Site in MEKs Mediates High-affinity Binding to MAP Kinases and Cooperates with a Scaffold Protein to Enhance Signal Transmission

2001 • 179 citations

An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors

2002 • 173 citations

Identification of a Cytoplasmic-Retention Sequence in ERK2

1999 • 136 citations

Interaction of Mitogen-activated Protein Kinases with the Kinase Interaction Motif of the Tyrosine Phosphatase PTP-SL Provides Substrate Specificity and Retains ERK2 in the Cytoplasm

1999 • 129 citations

Protein modification: Docking sites for kinases

1999 • 124 citations

The N-terminal ERK-binding Site of MEK1 Is Required for Efficient Feedback Phosphorylation by ERK2 in Vitro and ERK Activation in Vivo

1999 • 107 citations

Hydrophobic as Well as Charged Residues in Both MEK1 and ERK2 Are Important for Their Proper Docking

2001 • 86 citations

Regulation of Stress-responsive Mitogen-activated Protein (MAP) Kinase Pathways by TAO2

2001 • 81 citations

Specificity Determinants in MAPK Signaling to Transcription Factors

2002 • 80 citations

Allosteric enzymes as models for chemomechanical energy transducing assemblies

1996 • 25 citations

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Crystal Structures of MAP Kinase p38 Complexed to the Docking Sites on Its Nuclear… (2002) – Molecular Cell | Metascience Observatory Explorer