Formation of an hERalpha-COUP-TFI complex enhances hERalpha AF-1 through Ser118 phosphorylation by MAPK

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

1995 • 3,456 citations

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

1995 • 1,973 citations

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1999 • 1,965 citations

Mechanisms of Estrogen Action

2001 • 1,945 citations

Orphan Nuclear Receptors: From Gene to Function*

1999 • 789 citations

Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

1997 • 543 citations

Allosteric effects of DNA on transcriptional regulators

1998 • 488 citations

Activation of the ovalbumin gene by the estrogen receptor involves the Fos-Jun complex

1990 • 486 citations

Ligand-Independent Recruitment of SRC-1 to Estrogen Receptor β through Phosphorylation of Activation Function AF-1

1999 • 460 citations

Phosphorylation of the human estrogen receptor. Identification of hormone-regulated sites and examination of their influence on transcriptional activity.

1994 • 460 citations

The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.

1996 • 453 citations

Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.

1993 • 451 citations

Increasing the Complexity of Coactivation in Nuclear Receptor Signaling

1999 • 449 citations

Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1

2000 • 405 citations

Phosphorylation of the Nuclear Receptor SF-1 Modulates Cofactor Recruitment

1999 • 374 citations

Steroid hormone receptors and their regulation by phosphorylation

1996 • 361 citations

Purification and Identification of p68 RNA Helicase Acting as a Transcriptional Coactivator Specific for the Activation Function 1 of Human Estrogen Receptor α

1999 • 359 citations

Activation Function 2 in the Human Androgen Receptor Ligand Binding Domain Mediates Interdomain Communication with the NH2-terminal Domain

1999 • 354 citations

pp90^rsk1 Regulates Estrogen Receptor-Mediated Transcription through Phosphorylation of Ser-167

1998 • 348 citations

Interdomain communication regulating ligand binding by PPAR-γ

1998 • 344 citations

Estrogens and breast cancer

1996 • 343 citations

Activation of Estrogen Receptor α by S118 Phosphorylation Involves a Ligand-Dependent Interaction with TFIIH and Participation of CDK7

2000 • 286 citations

Minireview: Genomic Organization of the Human ERα Gene Promoter Region

2001 • 255 citations

Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors.

1993 • 245 citations

Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization

1997 • 215 citations

Potentiation of Human Estrogen Receptor α Transcriptional Activation through Phosphorylation of Serines 104 and 106 by the Cyclin A-CDK2 Complex

1999 • 200 citations

Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor.

1994 • 165 citations

p300 Mediates Functional Synergism between AF-1 and AF-2 of Estrogen Receptor α and β by Interacting Directly with the N-terminal A/B Domains

2000 • 154 citations

Synergism Between ERα Transactivation Function 1 (AF-1) and AF-2 Mediated by Steroid Receptor Coactivator Protein-1: Requirement for the AF-1 α-Helical Core and for a Direct Interaction Between the N- and C-Terminal Domains

2001 • 154 citations

Glucocorticoid Receptor/Signal Transducer and Activator of Transcription 5 (STAT5) Interactions Enhance STAT5 Activation by Prolonging STAT5 DNA Binding and Tyrosine Phosphorylation

1999 • 123 citations

Chicken ovalbumin upstream promoter transcription factor (COUP-TF): Expression during mouse embryogenesis

1995 • 118 citations

Chicken Ovalbumin Upstream Promoter-Transcription Factor Interacts with Estrogen Receptor, Binds to Estrogen Response Elements and Half-Sites, and Inhibits Estrogen-induced Gene Expression

1997 • 114 citations

Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast

1992 • 103 citations

Interdomain Signaling in a Two-domain Fragment of the Human Glucocorticoid Receptor

1999 • 102 citations

Structure and Function of Estrogen Receptors

1995 • 100 citations

Steroidogenic factor 1 and estradiol receptor act in synergism to regulate the expression of the salmon gonadotropin II beta subunit gene.

1996 • 93 citations

The N-terminal Region of the Human Progesterone A-receptor

2000 • 90 citations

Estrogens and health in males

2001 • 76 citations

Chicken Ovalbumin Upstream Promoter Transcription Factors Act as Auxiliary Cofactors for Hepatocyte Nuclear Factor 4 and Enhance Hepatic Gene Expression

1997 • 65 citations

Synergism between a half‐site and an imperfect estrogen‐responsive element, and cooperation with COUP‐TFI are required for estrogen receptor (ER) to achieve a maximal estrogen‐stimulation of rainbow trout ER gene

1999 • 49 citations

The orphan nuclear receptor, COUP-TF II, inhibits myogenesis by post-transcriptional regulation of MyoD function: COUP-TF II directly interacts with p300 and MyoD

1998 • 47 citations

Role of estrogen receptor ligand and estrogen response element sequence on interaction with chicken ovalbumin upstream promoter transcription factor (COUP-TF)

1999 • 46 citations

Separation and identification of type 1 and type 2 protein phosphatases from rabbit reticulocyte lysates.

1983 • 45 citations

The Nuclear Orphan Receptors COUP-TF and ARP-1 Positively Regulate the Trout Estrogen Receptor Gene through Enhancing Autoregulation

1997 • 44 citations

Identification of an Estrogen-Mediated Deoxyribonucleic Acid-Binding Independent Transactivation Pathway on the Epidermal Growth Factor Receptor Gene Promoter*

2000 • 44 citations

Transcription Activation by the Orphan Nuclear Receptor, Chicken Ovalbumin Upstream Promoter-Transcription Factor I (COUP-TFI)

2000 • 42 citations

Transcriptional Regulation of the Hepatocyte Growth Factor Gene by the Nuclear Receptors Chicken Ovalbumin Upstream Promoter Transcription Factor and Estrogen Receptor

1997 • 42 citations

COUP-TFI (Chicken Ovalbumin Upstream Promoter-Transcription Factor I) Regulates Cell Migration and Axogenesis in Differentiating P19 Embryonal Carcinoma Cells

2000 • 36 citations

Increase in the Stability and Helical Content of Estrogen Receptor α in the Presence of the Estrogen Response Element: Analysis by Circular Dichroism Spectroscopy

2001 • 36 citations

Nuclear orphan receptors COUP-TFII and Ear-2: presence in oxytocin-producing uterine cells and functional interaction with the oxytocin gene promoter

1998 • 32 citations

Estrogenic effect on the expression of estrogen receptor, COUP-TF, and lactoferrin mRNA in developing mouse tissues

1996 • 28 citations