The Development and Use of Phospho-Specific Antibodies to Study Protein Phosphorylation

Antibodies, a laboratory manual

1989 • 12,929 citations

DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2

1997 • 2,089 citations

Solid Phase Peptide Synthesis

1976 • 1,798 citations

Regulation of the specific DNA binding function of p53

1992 • 914 citations

DNA damage induces phosphorylation of the amino terminus of p53

1997 • 829 citations

Solid phase peptide synthesis; a practical approach

1991 • 772 citations

The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2.

1996 • 586 citations

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

1998 • 471 citations

Regulation of the p70 S6 Kinase by Phosphorylation in Vivo

1998 • 375 citations

Allosteric activation of latent p53 tetramers

1994 • 302 citations

The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.

1990 • 277 citations

Phosphorylation of Serine 392 Stabilizes the Tetramer Formation of Tumor Suppressor Protein p53

1997 • 249 citations

Mutant conformation of p53

1992 • 214 citations

Characterisation of Epitopes on Human p53 using Phage-displayed Peptide Libraries: Insights into Antibody-Peptide Interactions

1995 • 180 citations

Precise epitope mapping of the murine transformation-associated protein, p53.

1985 • 139 citations

Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers

1999 • 138 citations

[23] Production of phosphorylation state-specific antibodies

1991 • 132 citations

DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site

1998 • 106 citations

Conformational changes in p53 analysed using new antibodies to the core DNA binding domain of the protein.

1995 • 71 citations

Recombinant cyclic AMP response element binding protein (CREB) phosphorylated on Ser-133 is transcriptionally active upon its introduction into fibroblast nuclei.

1994 • 68 citations

Elevated levels of wild-type p53 induced by radiolabeling of cells leads to apoptosis or sustained growth arrest

1995 • 62 citations

Phosphopeptide Mapping and Phosphoamino Acid Analysis on Cellulose Thin-Layer Plates

1994 • 45 citations

Dephosphorylation of p53 at Ser20 after cellular exposure to low levels of non-ionizing radiation

1999 • 41 citations

p53-Dependent growth arrest and altered p53-immunoreactivity following metabolic labelling with 32P ortho-phosphate in human fibroblasts

1999 • 33 citations

Identification of an allosteric binding site on the transcription factor p53 using a phage-displayed peptide library

1998 • 33 citations

p53 expression in cultured cells following radioisotope labelling

1994 • 28 citations

Chemical synthesis of phosphopeptides using the arylthio group for protection of phosphate: application to identification of cdc2 kinase phosphorylation sites

1995 • 6 citations