Macrophage-Derived Growth Factors

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

1988 • 3,984 citations

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Secretory products of macrophages.

1987 • 2,670 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

Molecular cloning and expression of human hepatocyte growth factor

1989 • 2,191 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF

1989 • 2,090 citations

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

The biology of interleukin-6

1989 • 1,964 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1990 • 1,763 citations

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

1989 • 1,747 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

1987 • 1,667 citations

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

1990 • 1,650 citations

The Cell Biology of Macrophage Activation

1984 • 1,623 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin.

1978 • 1,530 citations

Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

1986 • 1,521 citations

The biology of interleukin-6

1989 • 1,459 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Perivascular Microglial Cells of the CNS Are Bone Marrow-Derived and Present Antigen in Vivo

1988 • 1,451 citations

The role of the macrophage in wound repair. A study with hydrocortisone and antimacrophage serum.

1975 • 1,445 citations

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

1986 • 1,305 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Cytokines and endothelial cell biology

1990 • 1,275 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

1987 • 1,243 citations

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1985 • 1,240 citations

Peptide Growth Factors and Their Receptors

1991 • 1,221 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

Interleukin-1 and Its Biologically Related Cytokines

1989 • 1,180 citations

Structure and expression of a cloned cDNA for human interleukin-2

1983 • 1,176 citations

Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI

1990 • 1,155 citations

Cloning and expression of the human erythropoietin gene.

1985 • 1,144 citations

Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor

1990 • 1,143 citations

Neutrophil Mac-1 and MEL-14 Adhesion Proteins Inversely Regulated by Chemotactic Factors

1989 • 1,135 citations

Wound Macrophages Express TGF-α and Other Growth Factors in Vivo: Analysis by mRNA Phenotyping

1988 • 1,107 citations

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

1990 • 1,095 citations

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.

1986 • 1,079 citations

Cloning and Expression of the Human Interleukin-6 (BSF-2/IFNβ 2) Receptor

1988 • 1,063 citations

The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

1989 • 1,060 citations

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

1985 • 1,056 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

The Basis for the Immunoregulatory Role of Macrophages and Other Accessory Cells

1987 • 1,040 citations

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.

1988 • 1,039 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.

1990 • 1,012 citations

The Granulocyte-Macrophage Colony-Stimulating Factors

1985 • 1,007 citations

Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve

1987 • 1,000 citations

Isolation of the bovine and human genes for müllerian inhibiting substance and expression of the human gene in animal cells

1986 • 997 citations

Human KGF is FGF-Related with Properties of a Paracrine Effector of Epithelial Cell Growth

1989 • 989 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins

1990 • 977 citations

Molecular cloning and expression of a receptor for human tumor necrosis factor

1990 • 973 citations

γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins

1985 • 949 citations

Insulin-like growth factors and their binding proteins

1990 • 929 citations

Effect of Neuropeptides on Production of Inflammatory Cytokines by Human Monocytes

1988 • 929 citations

cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

1988 • 896 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

The Transforming Growth Factor-βs

1991 • 882 citations

Deactivation of macrophages by transforming growth factor-β

1988 • 876 citations

Transforming Growth Factor-α: a More Potent Angiogenic Mediator than Epidermal Growth Factor

1986 • 856 citations

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

1988 • 845 citations

Inhibins, Activins, and Follistatins: Gonadal Proteins Modulating the Secretion of Follicle-Stimulating Hormone

1988 • 826 citations

Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3

1986 • 823 citations

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

1984 • 820 citations

Activated macrophages induce vascular proliferation

1977 • 818 citations

TUMOR NECROSIS, CACHEXIA, SHOCK, AND INFLAMMATION: A COMMON MEDIATOR

1988 • 814 citations

THE IMMUNOLOGICAL BASIS OF ACQUIRED CELLULAR RESISTANCE

1964 • 804 citations

Basic and Clinical Immunology.

1979 • 790 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line.

1989 • 753 citations

The Transforming Growth Factor-βs

1990 • 741 citations

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor

1989 • 726 citations

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF

1985 • 719 citations

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

1987 • 718 citations

Three different fibronectin mRNAs arise by alternative splicing within the coding region

1983 • 713 citations

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages.

1987 • 711 citations

Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

1990 • 710 citations

Transforming growth factor α

1988 • 707 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

Oxygen Tension Regulates the Expression of Angiogenesis Factor by Macrophages

1983 • 689 citations

Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization

1986 • 679 citations

The TGF-β family of growth and differentiation factors

1987 • 675 citations

Granulocyte- and granulocyte– macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate

1989 • 652 citations

Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A.

1987 • 651 citations

Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.

1989 • 651 citations

The platelet-derived growth factor

1978 • 649 citations

Interleukin-1 Mitogenic Activity for Fibroblasts and Smooth Muscle Cells Is Due to PDGF-AA

1989 • 648 citations

The Molecular Basis of Blood Diseases.

1987 • 648 citations

Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment

1987 • 636 citations

Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor

1985 • 633 citations

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1989 • 624 citations

Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein

1990 • 609 citations

The Activation of Mononuclear Phagocytes: Fact, Fancy, and Future

1978 • 609 citations

Human basic fibroblast growth factor: nucleotide sequence and genomic organization.

1986 • 604 citations

The macrophage response to central and peripheral nerve injury. A possible role for macrophages in regeneration.

1987 • 596 citations

Human monocyte chemoattractant protein‐1 (MCP‐1) Full‐length cDNA cloning, expression in mitogen‐stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE

1989 • 593 citations

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity.

1986 • 592 citations

Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms.

1989 • 591 citations

Structure and Function of Human Amphiregulin: A Member of the Epidermal Growth Factor Family

1989 • 586 citations

Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation

1986 • 577 citations

Interleukin 1: An Immunological Perspective

1985 • 576 citations

Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.

1990 • 569 citations

Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes.

1989 • 567 citations

The Cholinergic Neuronal Differentiation Factor from Heart Cells Is Identical to Leukemia Inhibitory Factor

1989 • 557 citations

Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors.

1990 • 557 citations

OP-1 cDNA encodes an osteogenic protein in the TGF-beta family.

1990 • 554 citations

Molecular Cloning of a Complementary DNA Encoding Human Macrophage-Specific Colony-Stimulating Factor (CSF-1)

1985 • 542 citations

Prostaglandins as endogenous mediators of interleukin 1 production.

1986 • 541 citations

Tumor necrosis factor is chemotactic for monocytes and polymorphonuclear leukocytes.

1987 • 533 citations

A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve.

1989 • 532 citations

Recombinant human TNF induces production of granulocyte–monocyte colony-stimulating factor

1986 • 528 citations

An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family

1987 • 525 citations

Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor

1983 • 520 citations

Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8.

1989 • 515 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

Macrophage production of transforming growth factor beta and fibroblast collagen synthesis in chronic pulmonary inflammation.

1989 • 502 citations

Secretory products of macrophages and their physiological functions

1984 • 494 citations

The murine transforming growth factor-beta precursor.

1986 • 492 citations

Identification of a membrane-associated interleukin 1 in macrophages.

1985 • 487 citations

Human β-nerve growth factor gene sequence highly homologous to that of mouse

1983 • 486 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor

1983 • 474 citations

ON THE PERMANENT LIFE OF TISSUES OUTSIDE OF THE ORGANISM

1912 • 473 citations

Identification and characterization of an inhibitor of haemopoietic stem cell proliferation

1990 • 470 citations

Interferon-like sequence of ovine trophoblast protein secreted by embryonic trophectoderm

1987 • 464 citations

Identification and cloning of localized maternal RNAs from xenopus eggs

1985 • 464 citations

Cloning and expression of murine immune interferon cDNA.

1983 • 455 citations

Platelet factor 4 is chemotactic for neutrophils and monocytes.

1981 • 444 citations

Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells.

1989 • 444 citations

Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.

1988 • 444 citations

A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity

1989 • 442 citations

Soluble cytokine receptors are present in normal human urine.

1989 • 441 citations

The Human Preproendothelin-1 Gene

1989 • 441 citations

Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets

1986 • 439 citations

Transmembrane TGF-α precursors activate EGF/TGF-α receptors

1989 • 432 citations

Identification and characterization of macrophage inflammatory protein 2.

1989 • 432 citations

HEMOPOIETIC CELL GROWTH FACTORS AND THEIR RECEPTORS

1989 • 432 citations

Vasoconstriction: A New Activity for Platelet-Derived Growth Factor

1986 • 430 citations

Purification, Cloning, and Expression of Ciliary Neurotrophic Factor (CNTF)

1989 • 429 citations

The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.

1988 • 425 citations

Induction of Macrophage Tumoricidal Activity by Granulocyte-Macrophage Colony-Stimulating Factor

1986 • 418 citations

Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins.

1989 • 411 citations

Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro.

1986 • 398 citations

Macrophage growth factor CSF-1 stimulates human monocyte production of interferon, tumor necrosis factor, and colony stimulating activity.

1986 • 397 citations

A new type of transforming growth factor-beta, TGF-beta 3.

1988 • 396 citations

Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production.

1989 • 394 citations

Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor.

1985 • 394 citations

cDNA sequences of two inducible T-cell genes.

1989 • 392 citations

A Macrophage-Derived Factor Required by Plasmacytomas for Survival and Proliferation in Vitro

1986 • 391 citations

Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.

1987 • 387 citations

Suppression of Macrophage Activation and T-Lymphocyte Function in Hypoprolactinemic Mice

1988 • 387 citations

Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage

1987 • 384 citations

The concept of the activated macrophage.

1978 • 383 citations

Novel method for studying mRNA phenotypes in single or small numbers of cells

1989 • 382 citations

Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats.

1987 • 381 citations

Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity

1986 • 380 citations

Human interleukin 1 is a cytocidal factor for several tumor cell lines.

1985 • 380 citations

Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation

1987 • 377 citations

Human Blood Monocytes: Stimulators of Granulocyte and Mononuclear Colony Formation in vitro

1972 • 374 citations

Interleukin 1 stimulation of collagenase production by cultured fibroblasts.

1983 • 373 citations

Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor

1985 • 372 citations

Epithelial Wound Healing Enhanced by Transforming Growth Factor-α and Vaccinia Growth Factor

1987 • 368 citations

Corticotropin releasing factor induction of leukocyte-derived immunoreactive ACTH and endorphins

1986 • 361 citations

Cultured human vascular endothelial cells acquire adhesiveness for neutrophils after stimulation with interleukin 1, endotoxin, and tumor-promoting phorbol diesters.

1986 • 360 citations

Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages.

1986 • 360 citations

Induction of transforming growth factor-α in activated human alveolar macrophages

1988 • 359 citations

Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin.

1988 • 357 citations

Cloning and expression of the hyman erythropoietin gene

1985 • 353 citations

Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.

1985 • 344 citations

The molecular basis of blood diseases

1988 • 341 citations

Domains of laminin with growth-factor activity

1989 • 341 citations

Polypeptide Growth Factors: Roles In Normal And Abnormal Cell Growth

1987 • 339 citations

Human IL-3 and GM-CSF Act Synergistically in Stimulating Hematopoiesis in Primates

1988 • 333 citations

Molecular Cloning and Expression of Neuroleukin, a Neurotrophic Factor for Spinal and Sensory Neurons

1986 • 332 citations

Modulation of cytokine production by transforming growth factor-beta.

1989 • 331 citations

Identification of another member of the transforming growth factor type beta gene family.

1988 • 326 citations

Human epidermal growth factor precursor: cDNA sequence, expressionin vitroand gene organization

1986 • 321 citations

mRNA decay: Finding the right targets

1989 • 318 citations

Amino acid sequence of human platelet factor 4.

1977 • 318 citations

Cloning, sequence, and expression of a human granulocyte/macrophage colony-stimulating factor.

1985 • 314 citations

Fibronectin is produced by human macrophages.

1980 • 311 citations

Structure of two human ovarian inhibins

1986 • 307 citations

Insulin Degradation: Mechanisms, Products, and Significance*

1988 • 305 citations

Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E.

1981 • 302 citations

A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines.

1990 • 302 citations

Recombinant interleukin-2 directly augments the cytotoxicity of human monocytes

1987 • 301 citations

Genomic structure of the murine IL-6 gene. High degree conservation of potential regulatory sequences between mouse and human.

1988 • 297 citations

Interleukin 1 increases the binding of human B and T lymphocytes to endothelial cell monolayers.

1986 • 296 citations

Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.

1989 • 294 citations

Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin 1.

1985 • 294 citations

cDNA cloning of murine interleukin-HP1: homology with human interleukin 6

1988 • 292 citations

Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.

1989 • 288 citations

Cloning and characterization of a cDNA for murine macrophage inflammatory protein (MIP), a novel monokine with inflammatory and chemokinetic properties.

1988 • 285 citations

Monocyte-Derived Human B-Cell Growth Factor Identified as Interferon-β ₂ (BSF-2, IL-6)

1988 • 281 citations

Respiratory burst in adherent human neutrophils: triggering by colony- stimulating factors CSF-GM and CSF-G

1989 • 277 citations

Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells

1988 • 273 citations

Cloning and sequence analysis of cDNA species coding for the two subunits of inhibin from bovine follicular fluid.

1986 • 273 citations

Hepatocyte-stimulating factor III shares structural and functional identity with leukemia-inhibitory factor.

1989 • 272 citations

Colony-stimulating factor-induced monocyte survival and differentiation into macrophages in serum-free cultures.

1987 • 270 citations

Two interleukin 1 genes in the mouse: cloning and expression of the cDNA for murine interleukin 1 beta.

1986 • 267 citations

Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis

1990 • 266 citations

Limitation of Excessive Myelopoiesis by the Intrinsic Modulation of Macrophage-Derived Prostaglandin E

1978 • 263 citations

Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro.

1983 • 261 citations

Macrophages specifically regulate the concentration of their own growth factor in the circulation.

1987 • 259 citations

Active and latent forms of transforming growth factor beta activity in synovial effusions.

1989 • 258 citations

Structure of the chromosomal gene for granulocyte-macrophage colony stimulating factor: comparison of the mouse and human genes.

1985 • 257 citations

The Platelet-derived Growth Factor-inducible KC Gene Encodes a Secretory Protein Related to Platelet α-Granule Proteins

1989 • 257 citations

Resolution of the two components of macrophage inflammatory protein 1, and cloning and characterization of one of those components, macrophage inflammatory protein 1 beta.

1988 • 254 citations

Mouse macrophage hemagglutinin (sheep erythrocyte receptor) with specificity for sialylated glycoconjugates characterized by a monoclonal antibody.

1989 • 252 citations

The molecular biology of platelet-derived growth factor

1983 • 252 citations

Molecular characterization of a gene of the ‘EGF family’ expressed in undifferentiated human NTERA2 teratocarcinoma cells.

1989 • 251 citations

BASIC AND CLINICAL IMMUNOLOGY

1988 • 246 citations

Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts.

1988 • 244 citations

Benzodiazepine Receptor-Mediated Chemotaxis of Human Monocytes

1985 • 239 citations

Additive effects of interleukin 1 and tumour necrosis factor-alpha on the accumulation of the three granulocyte and macrophage colony-stimulating factor mRNAs in human endothelial cells.

1987 • 238 citations

Induction of mRNA for a serine protease and a beta-thromboglobulin-like protein in mitogen-stimulated human leukocytes.

1987 • 236 citations

Stimulation of in vitro human skin collagenase expression by platelet-derived growth factor.

1985 • 236 citations

Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus.

1986 • 234 citations

Complementary Deoxyribonucleic Acid Cloning of a Messenger Ribonucleic Acid Encoding Transforming Growth Factor β 4 from Chicken Embryo Chondrocytes

1988 • 227 citations

Transforming growth factor-beta activity is potentiated by heparin via dissociation of the transforming growth factor-beta/alpha 2-macroglobulin inactive complex.

1989 • 225 citations

The reticuloendothelial system: A comprehensive treatise

1984 • 224 citations

Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils.

1989 • 224 citations

Macrophage Inflammatory Protein-1: a Prostaglandin-Independent Endogenous Pyrogen

1989 • 222 citations

Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact

1984 • 222 citations

GM-CSF induces human neutrophil IgA-mediated phagocytosis by an IgA Fc receptor activation mechanism

1988 • 219 citations

Isolation of a nonmitogenic angiogenesis factor from wound fluid.

1982 • 219 citations

Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone.

1987 • 217 citations

Stimulus-dependent myristoylation of a major substrate for protein kinase C

1988 • 216 citations

Sequences of liver cDNAs encoding two different mouse insulin-like growth factor I precursors

1986 • 215 citations

Complete covalent structure of human .beta.-thromboglobulin

1978 • 215 citations

Complementary DNA cloning and sequencing of rat ovarian basic fibroblast growth factor and tissue distribution study of its mRNA

1988 • 210 citations

Lipoprotein Uptake by Neuronal Growth Cones in Vitro

1987 • 209 citations

Cultured human monocytes synthesize and secrete alpha2-macroglobulin.

1977 • 209 citations

A Newly Defined Property of Somatotropin: Priming of Macrophages for Production of Superoxide Anion

1988 • 208 citations

Autocrine β-related interferon controls c-myc suppression and growth arrest during hematopoietic cell differentiation

1986 • 206 citations

A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes.

1989 • 206 citations

Human-Proto-Oncogene Nucleotide Sequences Corresponding to the Transforming Region of Simian Sarcoma Virus

1984 • 203 citations

Opinions

1978 • 203 citations

Transforming Growth Factor-β2: cDNA Cloning and Sequence Analysis

1988 • 200 citations

Structure of the Rat Interleukin 6 Gene and Its Expression in Macrophage-derived Cells

1989 • 199 citations

A lethal myeloproliferative syndrome in mice transplanted with bone marrow cells infected with a retrovirus expressing granulocyte-macrophage colony stimulating factor.

1989 • 198 citations

Induction of fibronectin gene transcription and mRNA is a primary response to growth-factor stimulation of AKR-2B cells.

1988 • 193 citations

Murine erythropoietin gene: cloning, expression, and human gene homology.

1986 • 193 citations

Isolation and characterization of the cDNA for murine granulocyte colony-stimulating factor.

1986 • 188 citations

The neutrophil-activating peptide NAF/NAP-1 induces histamine and leukotriene release by interleukin 3-primed basophils.

1989 • 186 citations

Induction of collagenase secretion in human fibroblast cultures by growth promoting factors.

1985 • 186 citations

The human prothymosin alpha gene is polymorphic and induced upon growth stimulation: evidence using a cloned cDNA.

1986 • 185 citations

Expression of the gastrin-releasing peptide gene in human small cell lung cancer. Evidence for alternative processing resulting in three distinct mRNAs.

1986 • 184 citations

The proliferative response in vitro of vascular endothelial and smooth muscle cells exposed to wound fluids and macrophages

1978 • 183 citations

Interleukin 1 releases histamine from human basophils and mast cells in vitro.

1987 • 181 citations

Epithelins 1 and 2: isolation and characterization of two cysteine-rich growth-modulating proteins.

1990 • 180 citations

Respiratory burst in adherent human neutrophils: triggering by colony- stimulating factors CSF-GM and CSF-G

1989 • 180 citations

Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family.

1984 • 179 citations

Upregulation of platelet-derived growth factor-A and -B gene expression in alveolar macrophages of individuals with idiopathic pulmonary fibrosis.

1990 • 179 citations

Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells.

1985 • 178 citations

Identification of a novel transforming growth factor-beta (TGF-beta 5) mRNA in Xenopus laevis.

1990 • 177 citations

Regulation of the expression of IL-6 in human monocytes.

1989 • 176 citations

Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily.

1989 • 176 citations

The monocyte-derived neutrophil activating peptide (NAP/interleukin 8) stimulates human neutrophil arachidonate-5-lipoxygenase, but not the release of cellular arachidonate.

1989 • 172 citations

Membrane interleukin 1 induction on human endothelial cells and dermal fibroblasts.

1987 • 171 citations

Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocyte-macrophage colony-stimulating factor

1987 • 169 citations

cDNA cloning and chromosomal assignment of the gene encoding endothelin 3

1989 • 167 citations

Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression.

1989 • 166 citations

Cytokines in chronic inflammatory arthritis. IV. Granulocyte/macrophage colony-stimulating factor-mediated induction of class II MHC antigen on human monocytes: a possible role in rheumatoid arthritis.

1989 • 166 citations

Characterization of the two nonallelic genes encoding mouse preproinsulin

1986 • 165 citations

Directed expression of NGF to pancreatic β cells in transgenic mice leads to selective hyperinnervation of the islets

1989 • 165 citations

Secretion of plasminogen activator by bone marrow-derived mononuclear phagocytes and its enhancement by colony-stimulating factor

1978 • 161 citations

Intron-exon structure of the human transforming growth factor-β precursor gene

1987 • 159 citations

Complementary DNA Cloning of the Murine Transforming Growth Factor-β3 (TGFβ3) Precursor and the Comparative Expression of TGFβ3 and TGFβ1 Messenger RNA in Murine Embryos and Adult Tissues

1989 • 157 citations

Structure and expression of cloned murine IFN-α genes

1983 • 154 citations

Structure, expression and function of a schwannoma-derived growth factor

1990 • 153 citations

Regulation of monokine gene expression: prostaglandin E2 suppresses tumor necrosis factor but not interleukin-1 alpha or beta-mRNA and cell-associated bioactivity.

1989 • 149 citations

Differential inhibition of transforming growth factor beta 1 and beta 2 activity by alpha 2-macroglobulin.

1990 • 148 citations

Secretion by human fibroblasts of monocyte chemoattractant protein-1, the product of gene JE.

1990 • 145 citations

Endogenous Regulation of Macrophage Proliferative Expansion by Colony-Stimulating Factor-Induced Interferon

1984 • 144 citations

Stimulation of neovascularization by human rheumatoid synovial tissue macrophages

1986 • 137 citations

Epidermal growth factor, like phorbol esters, induces plasminogen activator in HeLa cells

1978 • 137 citations

Human laminin B2 chain. Comparison of the complete amino acid sequence with the B1 chain reveals variability in sequence homology between different structural domains.

1988 • 134 citations

The effect of LPS on expression of the early "competence" genes JE and KC in murine peritoneal macrophages.

1987 • 132 citations

Cleavage of Parathyroid Hormone in Macrophage Endosomes Illustrates a Novel Pathway for Intracellular Processing of Proteins

1989 • 131 citations

Regulation of interleukin 6 receptor expression in human monocytes and monocyte-derived macrophages. Comparison with the expression in human hepatocytes.

1989 • 129 citations

Human monocyte adherence: a primary effect of chemotactic factors on the monocyte to stimulate adherence to human endothelium.

1987 • 128 citations

Activin B: Precursor Sequences, Genomic Structure andin VitroActivities

1989 • 126 citations

Transforming growth factor‐α

1990 • 126 citations

Agents that increase cAMP accumulation block endothelial c-sis induction by thrombin and transforming growth factor-beta.

1987 • 126 citations

Regulation of Class III Major Histocompatibility Complex Gene Products by Interleukin-1

1986 • 125 citations

Circulating interleukin 6 during a continuous infusion of tumor necrosis factor and interferon gamma.

1989 • 124 citations

Genetic analysis of the human tumor necrosis factor alpha/cachectin promoter region in a macrophage cell line.

1989 • 122 citations

Transforming Growth Factor

2008 • 121 citations

Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes.

1987 • 117 citations

Regulation of Monokine Gene Expression: Prostaglandin E2 Suppresses Tumor Necrosis Factor but Not Interleukin-1α or β-mRNA and Cell-Associated Bioactivity

1989 • 115 citations

Differential Production of Tumor Necrosis Factor, Macrophage Colony Stimulating Factor, and Interleukin 1 by Human Alveolar Macrophages

1989 • 115 citations

Myelopoietic enhancing effects of murine macrophage inflammatory proteins 1 and 2 on colony formation in vitro by murine and human bone marrow granulocyte/macrophage progenitor cells.

1989 • 114 citations

Administration of recombinant interferon gamma to cancer patients enhances monocyte secretion of hydrogen peroxide.

1985 • 110 citations

Immunocytochemical detection of interleukin 1 within stimulated human monocytes.

1986 • 105 citations

Epidermal growth factor

1987 • 103 citations

Cloning and tissue-specific expression of mouse macrophage colony-stimulating factor mRNA.

1987 • 101 citations

Molecular cloning of cDNA for human prothymosin alpha.

1986 • 100 citations

Differential effects of interferon-alpha and interferon-gamma on interleukin 1 secretion by monocytes.

1987 • 95 citations

Sequence of a Placental cDNA Encoding the Mouse Insulin-Like Growth Factor II Precursor

1986 • 93 citations

Structure of the rat platelet factor 4 gene: a marker for megakaryocyte differentiation.

1987 • 93 citations

The structure of the rabbit macrophage defensin genes and their organ-specific expression.

1989 • 92 citations

Stimulation of macrophage tumoricidal activity by the growth and differentiation factor CSF-1

1987 • 92 citations

Interleukin 1 can act as a B-cell growth and differentiation factor.

1985 • 90 citations

Platelet-derived Growth Factor-inducible Gene JE Is a Member of a Family of Small Inducible Genes Related to Platelet Factor 4

1989 • 90 citations

Extrarenal erythropoietin production by macrophages

1982 • 89 citations

Cloning and characterization of a novel T cell activation gene.

1987 • 88 citations

Characterization of a human interleukin 1 inhibitor.

1985 • 87 citations

Two burgeoning families of platelet factor 4-related proteins: mediators of the inflammatory response.

1990 • 87 citations

Regulation of insulin-like growth factor I gene expression in the human macrophage-like cell line U937.

1990 • 86 citations

Interleukin-4 stimulates human monocytes to produce tissue-type plasminogen activator

1989 • 85 citations

Passive immunization against tumor necrosis factor partially abrogates interleukin 2 toxicity.

1989 • 85 citations

Role of Na⁺/H⁺Exchange by Interferon-γ in Enhanced Expression of JE and I-A_βGenes

1989 • 83 citations

Relationship of macrophage Ia and membrane IL 1 expression to antigen presentation.

1985 • 82 citations

Molecular cloning and structure of the human interleukin-5 gene.

1987 • 81 citations

Onset of apoprotein E secretion during differentiation of mouse bone marrow-derived mononuclear phagocytes.

1983 • 79 citations

Tumor necrosis factor alpha stimulates the growth of the clonogenic cells of acute myeloblastic leukemia in synergy with granulocyte/macrophage colony-stimulating factor.

1989 • 78 citations

Differential expression of the human thymosin-beta 4 gene in lymphocytes, macrophages, and granulocytes.

1987 • 78 citations

Gene Structure and Expression

1996 • 78 citations

Human monocytes can produce tissue-type plasminogen activator.

1989 • 74 citations

Differential Expression of M-CSF, G-CSF, and GM-CSF by Human Monocytes

1990 • 72 citations

A secreted form of the human interleukin 2 receptor encoded by an "anchor minus" cDNA.

1986 • 69 citations

Nucleotide sequence of the murine TNF locus, including the TNF-α (tumor necrosis factor) and TNF-β (lymphotoxin) genes

1987 • 69 citations

Secretory products of phagocytes

1988 • 68 citations

Enhanced responsiveness of endothelium in the growing/motile state to tumor necrosis factor/cachectin.

1989 • 68 citations

Regulation of MHC class II gene expression in macrophages by hematopoietic colony-stimulating factors (CSF). Induction by granulocyte/macrophage CSF and inhibition by CSF-1.

1989 • 66 citations

Extrapancreatic insulin gene expression in the fetal rat.

1984 • 61 citations

Tumor Necrosis Factor Structure, Mechanism of Action, Role in Disease and Therapy

1991 • 57 citations

Feedback regulation of colony-stimulating factor (CSF-1)-induced macrophage proliferation by endogenous E prostaglandins and interferon-alpha/beta.

1984 • 52 citations

The mouse homologue ofhst/ k-FGF: sequence, genome organization and location relative toint-2

1989 • 51 citations

Monocyte-derived human B-cell growth factor identified as interferon-beta 2 (BSF-2, IL-6)

1988 • 51 citations

Macrophage Differentiation Inducing Factor from Human Monocytic Cells Is Equivalent to Murine Leukemia Inhibitory Factor

1989 • 50 citations

Complete sequence of murine myeloid leukaemia inhibuitory factor (LIF)

1988 • 50 citations

Cell type specific trans-acting factors are involved in alternative splicing of human fibronectin pre-mRNA.

1989 • 49 citations

Erythropoietin secretion by isolated rat Kupffer cells.

1984 • 48 citations

A novel subset of CD2-, CD3/T cell receptor alpha/beta+ human peripheral blood T cells. Phenotypic and functional characterization of interleukin 2-dependent CD2-CD3+ T cell clones.

1989 • 48 citations

Transforming growth factor-beta stimulates the expression of alpha 2-macroglobulin by cultured bovine adrenocortical cells.

1990 • 46 citations

The Rat Prepro Gastrin Releasing Peptide Gene is Transcribed from Two Initiation Sites in the Brain

1988 • 46 citations

Cooperative effects of colony-stimulating factor 1 and recombinant interleukin 2 on proliferation and induction of cytotoxicity of macrophage precursors generated from mouse bone marrow cell cultures.

1989 • 41 citations

Conversion of soluble immune response suppressor to macrophage-derived suppressor factor by peroxide.

1981 • 40 citations

Interleukin‐1 is a potent regulator of JE and KC gene expression in quiescent BALB/c fibroblasts

1989 • 38 citations

Porcine relaxin. Gene structure and expression.

1987 • 37 citations

Characterization and purification of mouse macrophage procoagulant-inducing factor.

1986 • 36 citations

RETRACTED: Isolation and complete amino acid sequence of human thymopoietin and splenin.

1987 • 35 citations

Induction of Endothelial Cell/Macrophage Procoagulant Activity: Synergistic Stimulation by Gamma Interferon and Granulocyte-Macrophage Colony Stimulating Factor

1989 • 35 citations

Bombesin in human and guinea pig alveolar macrophages.

1986 • 34 citations

mRNA Phenotyping for Studying Gene Expression in Small Numbers of Cells: Platelet-derived Growth Factor and Other Growth Factors in Wound-derived Macrophages

1990 • 32 citations

Changes of myelin proteins during Wallerian degeneration in situ and in millipore diffusion chambers preventing active phagocytosis

1986 • 31 citations

The Activated Macrophage and Granulomatous Inflammation

1989 • 30 citations

Tumor necrosis factor : structure, mechanism of action, role in disease and therapy

1990 • 29 citations

The early competence genes JE and KC are differentially regulated in murine peritoneal macrophages in response to lipopolysaccharide

1987 • 26 citations

Regulation of elastase and plasminogen activator secretion in resident and inflammatory macrophages by receptors for the Fc domain of immunoglobulin G.

1984 • 24 citations

Release from mouse macrophages of acidic isoferritins that suppress hematopoietic progenitor cells is induced by purified L cell colony stimulating factor and suppressed by human lactoferrin.

1985 • 23 citations

Stimulation of rat hepatocyte fibronectin production by monocyte-conditioned medium is due to interleukin 6.

1989 • 20 citations

Human laminin B2 chain

1988 • 19 citations

In situ hybridization analysis of macrophage-derived tumor necrosis factor and interleukin-1 mRNA.

1988 • 18 citations

Alterations in megakaryocyte and platelet compartments following in vivo IL-1 beta administration to normal mice.

1989 • 18 citations

Human peripheral blood monocytes secrete a unique form of PDGF.

1988 • 16 citations

Inducible gene expression of activin A/erythroid differentiation factor in HL-60 cells

1990 • 14 citations

Differential effects of epidermal growth factor, transforming growth factor-alpha, and vaccinia virus growth factor in the positive regulation of IFN-gamma production.

1989 • 11 citations

Angiogenesis: What Makes Blood Vessels Grow?

1986 • 10 citations

Characterization of a high‐molecular‐weight protein immunoprecipitated by platelet‐derived growth factor antisera

1988 • 6 citations

Interferon and Macrophages

1985 • 6 citations

Cloning of the mouse homolog of IP-10 from lymphokine-activated raw 264.7 cells

1989 • 1 citations

Deleted Work

1955 • 0 citations