Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Angiogenic Factors

1987 • 3,702 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

[1] Production of single-stranded plasmid DNA

1987 • 2,642 citations

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

1989 • 2,267 citations

Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF

1989 • 2,090 citations

Growth hormone receptor and serum binding protein: purification, cloning and expression

1987 • 1,540 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

Structural Characterization and Biological Functions of Fibroblast Growth Factor

1987 • 1,299 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

A putative signal peptidase recognition site and sequence in eukaryotic and prokaryotic signal peptides

1983 • 1,143 citations

Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.

1979 • 1,019 citations

Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells

1985 • 911 citations

Transforming Growth Factor-α: a More Potent Angiogenic Mediator than Epidermal Growth Factor

1986 • 856 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Long-term culture of capillary endothelial cells.

1979 • 780 citations

Synthetic oligonucleotide probes deduced from amino acid sequence data

1985 • 759 citations

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor

1989 • 726 citations

Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF.

1985 • 710 citations

Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization

1986 • 679 citations

Human basic fibroblast growth factor: nucleotide sequence and genomic organization.

1986 • 604 citations

Induction of terminal differentiation in human promyelocytic leukemia cells by tumor-promoting agents.

1979 • 513 citations

Role of prostaglandin E1 and copper in angiogenesis.

1982 • 393 citations

The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor.

1984 • 376 citations

Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor

1985 • 372 citations

Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies

1985 • 335 citations

Purification and properties of an endothelial cell growth factor from human platelets.

1987 • 330 citations

Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin 1.

1985 • 294 citations

Tumor Angiogenesis: Transfilter Diffusion Studies in the Hamster by the Transparent Chamber Technique<xref ref-type="fn" rid="FN2">2</xref>

1968 • 288 citations

Both normal and tumor cells produce basic fibroblast growth factor

1986 • 250 citations

[Progress in endocrinology].

1988 • 248 citations

Pituitary follicular cells produce basic fibroblast growth factor.

1987 • 200 citations

Role of growth factors in inflammation and repair

1989 • 189 citations

Bovine Granulosa Cells Produce Basic Fibroblast Growth Factor*

1987 • 175 citations

Evidence for Functional Communication between Folliculo-Stellate Cells and Hormone-Secreting Cells in Perifused Anterior Pituitary Cell Aggregates*

1987 • 165 citations

Leader length and secondary structure modulate mRNA function under conditions of stress.

1988 • 161 citations

Primary structural requirements for the enzymatic formation of the N-glycosidic bond in glycoproteins. Studies with alpha-lactalbumin

1978 • 124 citations

Choriocarcinoma: Transfilter Stimulation of Vasoproliferation in the Hamster Cheek Pouch—Studied by Light and Electron Microscopy<xref ref-type="fn" rid="FN2">2</xref>

1968 • 123 citations

Protein kinase C activation enhances cAMP accumulation in Swiss 3T3 cells: inhibition by pertussis toxin.

1987 • 100 citations

The genetic behaviour of a cloned mouse ribosomal DNA segment mimics mouse ribosomal gene evolution

1979 • 92 citations

Basic Fibroblast Growth Factor: Production and Growth Stimulation in Cultured Adrenal Cortex Cells*

1987 • 66 citations

Tumour angiogenesis factor (TAF) and its neutralisation by a xenogeneic antiserum

1979 • 57 citations

The Structure and Bacterial Expression of Three Distinct Bovine Interferon-β Genes

1984 • 57 citations

Stimulation of Endothelial Cell Proliferation by Rat Granulosa Cell-Conditioned Medium*

1986 • 53 citations

A mitogenic factor for endothelial cells obtained from mouse secondary mixed leukocyte cultures.

1986 • 34 citations

Release of an Endothelial Cell Growth Factor from Cultured Porcine Thyroid Follicles

1989 • 26 citations

The human osteosarcoma cell line U‐2 OS expresses a 3.8 kilobase mRNA which codes for the sequence of the PDGF‐B chain

1986 • 22 citations

[16] Culture and characterization of follicular cells of the bovine anterior pituitary and pars tuberalis

1986 • 16 citations

Regulation of ion transport in hypophysial pars intermedia follicular cell monolayers

1988 • 9 citations