Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

THE SMOOTH MUSCLE CELL

1971 • 1,571 citations

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors

1986 • 1,433 citations

Modulation of endothelial cell hemostatic properties by tumor necrosis factor.

1986 • 1,335 citations

Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein.

1984 • 1,249 citations

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1985 • 1,240 citations

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1985 • 1,125 citations

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.

1986 • 1,079 citations

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.

1985 • 833 citations

Tumor Growth and Neovascularization: An Experimental Model Using the Rabbit Cornea 2

1974 • 762 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

1986 • 742 citations

Tumour necrosis factors α and β inhibit virus replication and synergize with interferons

1986 • 726 citations

Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF.

1985 • 710 citations

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1.

1986 • 709 citations

Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors.

1986 • 674 citations

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

1984 • 638 citations

Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor.

1984 • 624 citations

Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation

1986 • 577 citations

Recombinant human TNF induces production of granulocyte–monocyte colony-stimulating factor

1986 • 528 citations

Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro.

1986 • 496 citations

Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets

1986 • 439 citations

Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers.

1986 • 401 citations

Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.

1986 • 396 citations

Antiviral effects of recombinant tumour necrosis factor in vitro

1986 • 392 citations

Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor

1985 • 372 citations

Tumor necrosis factor stimulates interleukin-1 and prostaglandin E2 production in resting macrophages

1986 • 344 citations

Transforming growth factor-beta inhibits endothelial cell proliferation

1986 • 313 citations

Inhibition of endothelial cell proliferation by type β-transforming growth factor: Interactions with acidic and basic fibroblast growth factors

1986 • 312 citations

Actions of Tumor Necrosis Factor on Cultured Vascular Endothelial Cells: Morphologic Modulation, Growth Inhibition, and Cytotoxicity

1986 • 300 citations

Isolation and partial molecular characterization of pituitary fibroblast growth factor.

1984 • 225 citations

Interrelationships of human interferon-gamma with lymphotoxin and monocyte cytotoxin.

1984 • 187 citations

Acidic fibroblast growth factor (FGF) from bovine brain: amino-terminal sequence and comparison with basic FGF.

1985 • 178 citations

The labelling of blood cells in plasma with¹¹¹In-tropolonate

1982 • 144 citations

Developing brain produces an angiogenesis factor.

1986 • 143 citations

The antiproliferative effect of interferon and the mitogenic activity of growth factors are independent cell cycle events

1985 • 84 citations

Antiadhesive properties of biological surfaces are protective against stimulated granulocytes.

1985 • 63 citations

Necrosin: purification and properties of a cytotoxin derived from a murine macrophage-like cell line.

1984 • 42 citations

Mechanism of the cytotoxic effect of tumor necrosis factor.

1985 • 35 citations

Cancer: Cell growth control mechanisms

1986 • 23 citations

Inhibitory effect of tumor necrosis serum on the metastasis of B-16 mouse melanoma cells.

1985 • 13 citations

A chemiluminescent assay for mycoplasmas in cell cultures

1985 • 13 citations