The Activated Macrophage and Granulomatous Inflammation

Secretory products of macrophages.

1987 • 2,670 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

The Cell Biology of Macrophage Activation

1984 • 1,623 citations

The granulomatous inflammatory response. A review.

1976 • 549 citations

Molecular mechanisms of signal transduction in macrophages

1987 • 331 citations

Inflammation: Basic Principles and Clinical Correlates

1988 • 275 citations

Molecular Transductional Mechanisms by which IFNγ and Other Signals Regulate Macrophage Development

1987 • 266 citations

Immunity in infective diseases

1905 • 252 citations

The monocyte in cellular immunity.

1970 • 159 citations

The structure of mononuclear phagocytes differentiating in vivo. I. Sequential fine and histologic studies of the effect of Bacillus Calmette-Guerin (BCG).

1974 • 142 citations

Regulation of tumor necrosis factor (TNF) expression: Interferon-γ enhances the accumulation of mRNA for TNF induced by lipopolysaccharide in murine peritoneal macrophages

1987 • 95 citations

The human interferon-gamma receptor. Purification, characterization, and preparation of antibodies.

1987 • 85 citations

Inflammatory Giant Cells

1982 • 84 citations

Role of interleukin 1 in experimental pulmonary granuloma in mice.

1985 • 77 citations

Contemporary Topics in Immunobiology

1973 • 69 citations

Biochemical and functional responses stimulated by platelet-activating factor in murine peritoneal macrophages [published erratum appears in J Cell Biol 1988 Sep;107(3):following 1260]

1988 • 64 citations

Role of lipoxygenase products in murine pulmonary granuloma formation.

1984 • 63 citations

Role of angiotensin-converting enzyme in Bacille Calmette-Guérin-induced granulomatous inflammation. Increased angiotensin-converting enzyme levels in lung lavage and suppression of inflammation with captopril.

1982 • 60 citations

Effect of SQ 14225, an inhibitor of angiotensin I-converting enzyme, on the granulomatous response to Schistosoma mansoni eggs in mice.

1981 • 59 citations

Monoclonal antibodies distinguish macrophages and epithelioid cells in sarcoidosis and leprosy.

1987 • 47 citations

Production of superoxide anion, prostaglandins, and hydroxyeicosatetraenoic acids by macrophages from hypersensitivity-type (Schistosoma mansoni egg) and foreign body-type granulomas

1983 • 47 citations

Immunoregulation of Granuloma Formation in Murine Schistosomiasis Mansoni^a

1986 • 46 citations

Modulation of mouse peritoneal macrophage Ia and human peritoneal macrophage HLA-DR expression by alpha 2-macroglobulin "fast" forms.

1987 • 46 citations

Isolated liver granulomas of murine Schistosoma mansoni contain components of the angiotensin system.

1983 • 44 citations

The structure of mononuclear phagocytes differentiating in vivo. II. The effect of Mycobacterium tuberculosis.

1975 • 43 citations

The Origin, Morphology, and Function of Epithelioid Cells

1982 • 42 citations

Ia antigen expression and antigen-presenting function by macrophages isolated from hypersensitivity granulomas.

1982 • 37 citations

Fibroblast Stimulation in Schistosomiasis. I. Stimulation in Vitro of Fibroblasts by Soluble Products of Egg Granulomas

1981 • 37 citations

Pathology of granulomas

1983 • 34 citations

Fibroblast stimulation in schistosomiasis. IV. Isolated egg granulomas elaborate a fibroblast chemoattractant in vitro.

1983 • 32 citations

Functional angiotensin II receptors on macrophages from isolated liver granulomas of murine Schistosoma mansoni.

1984 • 32 citations

Evidence that multinucleate giant cells are examples of mononuclear phagocytic differentiation

1986 • 32 citations

Fibroblast stimulation in schistosomiasis. II. Functional and biochemical characteristics of egg granuloma-derived fibroblast-stimulating factor.

1982 • 31 citations

Fibroblast stimulation in schistosomiasis. VII. Egg granulomas secrete factors that stimulate collagen and fibronectin synthesis.

1987 • 29 citations

Experimental mycobacterial granulomas in guinea pig lymph nodes: Ultrastructural observations

1981 • 28 citations

Immunologic and Nonimmunologic Activation of Macrophages

1980 • 28 citations

Cellular Aspects of Granulomas

1982 • 25 citations

Gene regulation in macrophage development and activation.

1989 • 24 citations

Isolated epithelioid cells from disaggregated BCG granulomas—an ultrastructural study

1982 • 24 citations

Tumoricidal macrophages isolated from liver granulomas of Schistosoma mansoni-infected mice.

1982 • 23 citations

Schistosome egg antigen(s) presentation and regulatory activity by macrophages isolated from vigorous or immunomodulated liver granulomas of Schistosoma mansoni-infected mice.

1984 • 23 citations

Characterization of regulatory (interferon-alpha/beta) and accessory (LAF/IL 1) monokine activities from liver granuloma macrophages of Schistosoma mansoni-infected mice.

1987 • 21 citations

Experimental epithelioid cell granulomas tubercle formation and immunological competence: An ultrastructural analysis

1983 • 21 citations

Analysis of cells of the mononuclear phagocyte series in experimental mycobacterial granulomas by monoclonal antibodies

1983 • 20 citations

Comparison of Fc, C3 receptors and Ia antigens on the inflammatory macrophage isolated from vigorous or immunomodulated liver granulomas of schistosome-infected mice.

1981 • 20 citations

The structure of mononuclear phagocytes differentiating in vivo. III. The effect of particulate foreign substances.

1977 • 20 citations

The artificial granuloma 1: In vitro lymphokine production by pulmonary artificial hypersensitivity granulomas

1980 • 18 citations

Dynamics of Arachidonic Acid Metabolism in Macrophages From Delayed-Type Hypersensitivity (Schistosoma mansoni egg) and Foreign-Body-Type Granulomas

1985 • 16 citations

Mesenchymal Target Cell Specificity of Egg Granuloma-Derived Fibroblast Growth Factor in Schistosomiasis

1987 • 15 citations

Induction of immune responses by schistosome granuloma macrophages.

1983 • 15 citations

Experimental granulomatosis

1986 • 15 citations

Immunostimulatory mouse granuloma protein.

1983 • 14 citations

Release of soluble factors from lymph nodes containing mycobacterial granulomas and their effect on fibroblast function in vitro

1981 • 13 citations

Microbicidal activity and morphological characteristics of lung macrophages in Mycobacterium bovis BCG cell wall-induced lung granuloma in mice

1984 • 13 citations

Isolated epithelioid cells from disaggregated BCG granulomas—some functional studies

1982 • 12 citations

Functional Aspects of Mononuclear Phagocyte Involvement in Lung Inflammation^a

1986 • 12 citations

Lysozyme production by a granuloma in vivo: Output in blood and lymph in relation to ultrastructure and immunochemistry

1980 • 12 citations

The mononuclear phagocyte system in granulomas

1985 • 11 citations

The production of plasminogen activator by afferent but not efferent lymph cells emigrating from chronic granulomatous lesions in sheep.

1982 • 11 citations

Variable severity and Ia antigen expression in streptococcal-cell-wall-induced hepatic granulomas in rats

1987 • 11 citations

The morphology, kinetics and fate of granulomas.

1980 • 11 citations

Angiotensin-1-converting enzyme activity of murine macrophages isolated from granulomas elicited by eggs of Schistosoma mansoni

1983 • 10 citations

Formation of Giant Cells in Vivo

1982 • 9 citations

Lysozyme and angiotensin converting enzyme levels in experimental mycobacterial granulomas.

1983 • 9 citations

Interleukin 1 and prostaglandin production by cells of the mononuclear phagocyte system isolated from mycobacterial granulomas

1987 • 9 citations

Detection of granuloma-associated plasminogen activator in experimental murine schistosomiasis

1985 • 6 citations

Oxygen Radicals and Arachidonate Metabolites in Lung Injury^a

1986 • 6 citations

Parallelism between Superoxide Production of Peritoneal Exudate Cells and Lung Granulomatous Response in Mice Vaccinated with BCG Cell Walls

1986 • 4 citations

Experimental Granulomas

1982 • 4 citations

Molecular mechanisms of cell control in macrophage activation

1988 • 3 citations