Characterization of the two nonallelic genes encoding mouse preproinsulin

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Ribonucleic acid isolated by cesium chloride centrifugation

1974 • 2,263 citations

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1977 • 1,252 citations

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

1981 • 910 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

The evolution of genes: the chicken preproinsulin gene

1980 • 725 citations

Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide

1977 • 713 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

Sequence of the human insulin gene

1980 • 553 citations

A bacterial clone synthesizing proinsulin.

1978 • 515 citations

The structure and evolution of the two nonallelic rat preproinsulin genes

1979 • 500 citations

Extraction of nucleic acids from agarose gels

1980 • 346 citations

Species variation in the amino acid sequence of insulin

1966 • 322 citations

In vitro packaging of a λ Dam vector containing EcoRI DNA fragments of Escherichia coli and phage P1

1977 • 319 citations

A convenient and adaptable package of computer programs for DNA and protein sequence management, analysis and homology determination

1984 • 285 citations

Cell-free synthesis of rat preproinsulins: characterization and partial amino acid sequence determination.

1976 • 279 citations

RNA-Mediated Gene Duplication: the Rat Preproinsulin I Gene Is a Functional Retroposon

1985 • 256 citations

STRUCTURE AND EVOLUTION OF THE INSULIN GENE

1985 • 252 citations

Chemistry of Insulin

1959 • 249 citations

Construction of coliphage lambda Charon vectors with BamHI cloning sites

1980 • 230 citations

Isolation and characterization of a cloned rat insulin gene

1979 • 229 citations

Definition of a novel promoter for the major adenovirus-associated virus mRNA

1980 • 187 citations

INSULIN BIOSYNTHESIS IN THE RAT: DEMONSTRATION OF TWO PROINSULINS

1969 • 155 citations

RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon.

1985 • 153 citations

[26] A sensitive and rapid method for recombinant phage screening

1979 • 150 citations

Transcriptional Control Regions: Nucleotide Sequence Requirements for Initiation by RNA Polymerase II and III

1981 • 125 citations

A convenient and adaptable package of DNA sequence analysis programs for microcomputers

1982 • 119 citations

Action of single-strand specific nucleases on model DNA heteroduplexes of defined size and sequence

1977 • 98 citations

Guinea pig preproinsulin gene: an evolutionary compromise?

1984 • 78 citations

[32] Purification and properties of S1 nuclease from Aspergillus

1980 • 73 citations

[1] New bacteriophage lambda vectors with positive selection for cloned insects

1983 • 65 citations

Comparison of the Nucleic Acid Sequence of Anglerfish and Mammalian Insulin mRNA's from Cloned cDNA's

1980 • 63 citations

Messenger RNA sequence and primary structure of preproinsulin in a primitive vertebrate, the Atlantic hagfish.

1981 • 61 citations

Cloning and nucleotide sequence analysis of the dog insulin gene. Coded amino acid sequence of canine preproinsulin predicts an additional C-peptide fragment.

1983 • 58 citations

MOUSE INSULINS — SEPARATION AND STRUCTURES

1971 • 45 citations

Nucleotide sequence analysis of the cloned salmon preproinsulin cDNA

1982 • 30 citations

Carp preproinsulin cDNA sequence and evolution of insulin genes

1983 • 30 citations

Sequence of a cDNA Encoding Syrian Hamster Preproinsulin

1984 • 28 citations

The nucleotide sequence of cDNA coding for preproinsulin from the primate Macacafascicularis

1982 • 24 citations

Sequence and evolution of guinea pig preproinsulin DNA.

1985 • 15 citations

Isolation and Partial Structural Analysis of Insulin from Mouse(Mus musculus)and Spiny Mouse(Acomys cahirinus)

1972 • 8 citations