The Transforming Growth Factor-βs

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

1986 • 1,617 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

Growth factors from murine sarcoma virus-transformed cells.

1978 • 1,457 citations

Arg-Gly-Asp: A versatile cell recognition signal

1986 • 1,413 citations

Some recent advances in the chemistry and biology of transforming growth factor-beta.

1987 • 1,308 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

1987 • 1,243 citations

Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid

1986 • 1,148 citations

Wound Macrophages Express TGF-α and Other Growth Factors in Vivo: Analysis by mRNA Phenotyping

1988 • 1,107 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin

1986 • 1,071 citations

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

1987 • 998 citations

Isolation of the bovine and human genes for müllerian inhibiting substance and expression of the human gene in animal cells

1986 • 997 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium.

1988 • 962 citations

Mesoderm induction in early Xenopus embryos by heparin-binding growth factors

1987 • 953 citations

Accelerated Healing of Incisional Wounds in Rats Induced by Transforming Growth Factor-β

1987 • 938 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors.

1987 • 895 citations

Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts*1

1988 • 887 citations

Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early xenopus embryo

1987 • 883 citations

Deactivation of macrophages by transforming growth factor-β

1988 • 876 citations

Estrogen Binding, Receptor mRNA, and Biologic Response in Osteoblast-Like Osteosarcoma Cells

1988 • 836 citations

Peptide growth factors are multifunctional

1988 • 835 citations

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

1987 • 791 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.

1986 • 777 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β

1987 • 747 citations

Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-beta.

1987 • 736 citations

Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β

1985 • 722 citations

The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors

1987 • 710 citations

Developmental Expression of PDGF, TGF-α, and TGF-β Genes in Preimplantation Mouse Embryos

1988 • 688 citations

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

1989 • 672 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.

1988 • 648 citations

Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription.

1984 • 623 citations

Purification and characterization of other distinct bone-inducing factors.

1988 • 621 citations

A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-β

1988 • 620 citations

Transforming growth factor beta is a bifunctional regulator of replication and collagen synthesis in osteoblast-enriched cell cultures from fetal rat bone.

1987 • 619 citations

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

1988 • 604 citations

Effects of transforming growth factor beta on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness.

1986 • 579 citations

Transforming growth factor β (TGFβ) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts

1987 • 579 citations

Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix.

1988 • 571 citations

Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells.

1986 • 570 citations

Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes.

1989 • 567 citations

Osteoblasts synthesize and respond to transforming growth factor-type beta (TGF-beta) in vitro.

1987 • 561 citations

Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium.

1986 • 559 citations

Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing.

1988 • 559 citations

Type beta transforming growth factor is an inhibitor of myogenic differentiation.

1986 • 559 citations

Distribution and modulation of the cellular receptor for transforming growth factor-beta.

1987 • 556 citations

Latent transforming growth factor-beta from human platelets. A high molecular weight complex containing precursor sequences.

1988 • 548 citations

Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells.

1986 • 542 citations

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

1986 • 541 citations

Cartilage-inducing factor-A. Apparent identity to transforming growth factor-beta.

1986 • 533 citations

Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos

1987 • 523 citations

Transforming growth factor production by chemically transformed cells.

1981 • 506 citations

Purification and characterization of two cartilage-inducing factors from bovine demineralized bone.

1985 • 503 citations

Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha.

1987 • 497 citations

The murine transforming growth factor-beta precursor.

1986 • 492 citations

Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation.

1988 • 483 citations

Correlation of fibrosis and transforming growth factor-beta type 2 levels in the eye.

1989 • 481 citations

Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblasts.

1984 • 477 citations

Tumor-promoting phorbol esters induce angiogenesis in vitro

1985 • 470 citations

Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts.

1987 • 467 citations

Immunodetection and quantitation of the two forms of transforming growth factor‐beta (TGF‐β1 and TGF‐β2) secreted by cells in culture

1989 • 453 citations

Tenascin: cDNA cloning and induction by TGF-beta.

1988 • 453 citations

Mesoderm Induction in Amphibians: the Role of TGF-β2-Like Factors

1988 • 452 citations

Polypeptide Transforming Growth Factors Isolated from Bovine Sources and Used for Wound Healing in Vivo

1983 • 451 citations

Expression of transforming growth factor-beta 1 in specific cells and tissues of adult and neonatal mice.

1989 • 451 citations

Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta.

1986 • 443 citations

Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets

1986 • 439 citations

Modulation of type beta transforming growth factor activity in bone cultures by osteotropic hormones.

1987 • 434 citations

Latent transforming growth factor-beta in serum. A specific complex with alpha 2-macroglobulin.

1987 • 434 citations

Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat.

1988 • 424 citations

Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability.

1988 • 420 citations

Transforming growth factor beta regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans.

1988 • 418 citations

Purification and initial characterization of a type beta transforming growth factor from human placenta.

1983 • 409 citations

Reversible Inhibition of Mammary Gland Growth by Transforming Growth Factor-β

1987 • 408 citations

Regulation of myogenic differentiation by type beta transforming growth factor.

1986 • 408 citations

Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells

1987 • 407 citations

Characterization of the Promoter Region of the Human Transforming Growth Factor-β1 Gene

1989 • 400 citations

A new type of transforming growth factor-beta, TGF-beta 3.

1988 • 396 citations

Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.

1988 • 392 citations

Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.

1987 • 387 citations

Alpha and beta human transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria.

1985 • 382 citations

Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors.

1983 • 381 citations

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.

1989 • 378 citations

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells.

1987 • 378 citations

Conversion of a high molecular weight latent β-TGF from chicken embryo fibroblasts into a low molecular weight active β-TGF under acidic conditions

1985 • 366 citations

Type beta transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts.

1985 • 364 citations

Signal transduction by guanine nucleotide binding proteins

1987 • 362 citations

Peptide growth factors and inflammation, tissue repair, and cancer.

1986 • 360 citations

Purification and properties of a type .beta. transforming growth factor from bovine kidney

1983 • 355 citations

Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action

1988 • 347 citations

Cellular receptors for type beta transforming growth factor. Ligand binding and affinity labeling in human and rodent cell lines.

1985 • 344 citations

Regulation of intestinal epithelial cell growth by transforming growth factor type beta.

1989 • 341 citations

Molecular Characterization of Fibroblast Growth Factor: Distribution and Biological Activities in Various Tissues

1986 • 340 citations

Transforming growth factor beta stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor by cultured human lung fibroblasts.

1988 • 340 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

T cell suppressor factor from human glioblastoma cells is a 12.5-kd protein closely related to transforming growth factor-beta.

1987 • 337 citations

Cartilage-inducing factor-B is a unique protein structurally and functionally related to transforming growth factor-beta.

1987 • 336 citations

Absence of TGF-β Receptors and Growth Inhibitory Responses in Retinoblastoma Cells

1988 • 331 citations

Identification of another member of the transforming growth factor type beta gene family.

1988 • 326 citations

Transforming growth factor-β inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor

1989 • 325 citations

Inhibitory effect of transforming growth factor-β on DNA synthesis of adult rat hepatocytes in primary culture

1985 • 325 citations

Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta.

1988 • 324 citations

Inhibitory action of transforming growth factor beta on endothelial cells.

1987 • 324 citations

Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids.

1989 • 320 citations

Inhibition of DNA synthesis in rat hepatocytes by platelet-derived type beta transforming growth factor.

1986 • 317 citations

Transforming growth factor-beta inhibits endothelial cell proliferation

1986 • 313 citations

Inhibition of endothelial cell proliferation by type β-transforming growth factor: Interactions with acidic and basic fibroblast growth factors

1986 • 312 citations

Transforming growth factor-beta-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells.

1988 • 305 citations

Effects of growth factors on an intestinal epithelial cell line: Transforming growth factor β inhibits proliferation and stimulates differentiation

1987 • 305 citations

Transforming growth factor-beta 1 modulates the expression of class II histocompatibility antigens on human cells.

1988 • 298 citations

Transforming growth factor beta inhibits formation of osteoclast-like cells in long-term human marrow cultures.

1988 • 297 citations

Transforming growth factors from neoplastic and nonneoplastic tissues.

1983 • 288 citations

Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis

1988 • 275 citations

Transforming growth factor beta regulates the metabolism of proteoglycans in bovine cartilage organ cultures.

1988 • 274 citations

Cloning and sequence analysis of cDNA species coding for the two subunits of inhibin from bovine follicular fluid.

1986 • 273 citations

Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide.

1988 • 273 citations

Developmental expression of transforming growth factors alpha and beta in mouse fetus.

1988 • 272 citations

Antibodies to the N-terminal portion of cartilage-inducing factor A and transforming growth factor beta. Immunohistochemical localization and association with differentiating cells.

1986 • 271 citations

Role for carbohydrate structures inTGF-β1 latency

1989 • 270 citations

Transforming growth factor-beta induction of type-1 plasminogen activator inhibitor. Pericellular deposition and sensitivity to exogenous urokinase.

1987 • 263 citations

Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells.

1982 • 263 citations

Purification and properties of porcine platelet-derived growth factor.

1984 • 260 citations

Fibronectin's cell-adhesive domain and an amino-terminal matrix assembly domain participate in its assembly into fibroblast pericellular matrix.

1987 • 255 citations

Transforming Growth Factor β: Biochemistry and Roles in Embryogenesis, Tissue Repair and Remodeling, and Carcinogenesis

1988 • 255 citations

Promoter Sequences of the Human Transforming Growth Factor-β1 Gene Responsive to Transforming Growth Factor-β1 Autoinduction

1989 • 254 citations

Insulin-Resistant Diabetes Due to a Point Mutation That Prevents Insulin Proreceptor Processing

1988 • 253 citations

Transforming growth factor-beta is a strong and fast acting positive regulator of the level of type-1 plasminogen activator inhibitor mRNA in WI-38 human lung fibroblasts.

1987 • 247 citations

Transforming growth factor-beta. A very potent inhibitor of myoblast differentiation, identical to the differentiation inhibitor secreted by Buffalo rat liver cells.

1986 • 247 citations

Growth modulation of mouse keratinocytes by transforming growth factors.

1988 • 242 citations

β-Transforming Growth Factor is stored in human blood platelets as a latent high molecular weight complex

1986 • 241 citations

The transforming growth factor-beta receptor type III is a membrane proteoglycan. Domain structure of the receptor.

1988 • 240 citations

Effects of growth factors in vivo. I. Cell ingrowth into porous subcutaneous chambers.

1987 • 239 citations

Differential effects of transforming growth factor-beta on the synthesis of extracellular matrix proteins by normal fetal rat calvarial bone cell populations.

1988 • 238 citations

Respiratory gas tensions and pH in healing wounds

1967 • 234 citations

Transforming growth factor-β controls receptor levels for epidermal growth factor in NRK fibroblasts

1984 • 232 citations

Transforming Growth Factor Beta-1 in Acute Myocardial Infarction in Rats

1988 • 232 citations

Beta-type transforming growth factor specifies organizational behavior in vascular smooth muscle cell cultures.

1987 • 229 citations

Complementary Deoxyribonucleic Acid Cloning of a Messenger Ribonucleic Acid Encoding Transforming Growth Factor β 4 from Chicken Embryo Chondrocytes

1988 • 227 citations

Differential effects of transforming growth factor-beta on proliferation of normal and malignant rat liver epithelial cells in culture.

1986 • 224 citations

Type 1 Transforming Growth Factor Beta: Amplified Expression and Secretion of Mature and Precursor Polypeptides in Chinese Hamster Ovary Cells

1987 • 224 citations

Transforming growth factor beta 1 selectively regulates early murine hematopoietic progenitors and inhibits the growth of IL-3-dependent myeloid leukemia cell lines.

1988 • 222 citations

Transforming growth factor beta (TGF-β) induces fibrosis in a fetal wound model

1988 • 220 citations

Transforming growth factor β gene maps to human chromosome 19 long arm and to mouse chromosome 7

1986 • 216 citations

Transforming growth factor‐beta modulates the expression of osteoblast and chondroblast phenotypes in vitro

1988 • 216 citations

Specific binding to cultured cells of 125I-labeled type beta transforming growth factor from human platelets.

1984 • 212 citations

Human transforming growth factor beta.alpha 2-macroglobulin complex is a latent form of transforming growth factor beta.

1988 • 209 citations

Inhibin and beta type transforming growth factor (TGFβ) have opposite modulating effects on the follicle stimulating hormone (FSH)-induced aromatase activity of cultured rat granulosa cells

1986 • 206 citations

Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type beta transforming growth factor.

1988 • 206 citations

Effects of bovine inhibin, transforming growth factor-β and bovine activin-A on granulosa cell differentiation

1987 • 205 citations

Regulation of fibronectin biosynthesis by dexamethasone, transforming growth factor beta, and cAMP in human cell lines.

1988 • 205 citations

Human transforming growth factor type .beta.2: production by a prostatic adenocarcinoma cell line, purification, and initial characterization

1987 • 204 citations

Ovarian Thecal Cells Produce Transforming Growth Factor-β Which Can Regulate Granulosa Cell Growth*

1987 • 201 citations

Transforming Growth Factor-β2: cDNA Cloning and Sequence Analysis

1988 • 200 citations

Transforming growth factor type beta specifically stimulates synthesis of proteoglycan in human adult arterial smooth muscle cells.

1987 • 198 citations

Type β transforming growth factor (TGFβ) regulation of alkaline phosphatase expression and other phenotype‐related mRNAs in osteoblastic rat osteosarcoma cells

1987 • 196 citations

Comparison of the biological actions of TGF beta‐1 and TGF beta‐2: Differential activity in endothelial cells

1988 • 195 citations

Type beta transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval.

1985 • 191 citations

SEQUENCES OF INTEREST: Complementary Deoxyribonucleic Acid Cloning of a Novel Transforming Growth Factor-β Messenger Ribonucleic Acid from Chick Embryo Chondrocytes

1988 • 191 citations

Inhibition of skeletal muscle satellite cell differentiation by transforming growth factor‐beta

1987 • 188 citations

Hepatic processing of transforming growth factor beta in the rat. Uptake, metabolism, and biliary excretion.

1987 • 184 citations

The high molecular weight receptor to transforming growth factor-beta contains glycosaminoglycan chains.

1988 • 178 citations

The antiproliferative effect of type beta transforming growth factor occurs at a level distal from receptors for growth-activating factors.

1986 • 177 citations

Identification of a novel transforming growth factor-beta (TGF-beta 5) mRNA in Xenopus laevis.

1990 • 177 citations

The Reversal of an Adriamycin® Induced Healing Impairment with Chemoattractants and Growth Factors

1986 • 175 citations

Purification of kidney epithelial cell growth inhibitors.

1980 • 174 citations

Enhanced expression of TGF-β and c-fos mRNAs in the growth plates of developing human long bones

1988 • 173 citations

Transforming growth factor-beta 1 (TGF-beta 1) and recombinant human tumor necrosis factor-alpha reciprocally regulate the generation of lymphokine-activated killer cell activity. Comparison between natural porcine platelet-derived TGF-beta 1 and TGF-beta 2, and recombinant human TGF-beta 1.

1988 • 168 citations

Regulation of proliferation and differentiation of respiratory tract epithelial cells by TGFβ

1986 • 166 citations

The Effect of Transforming Growth Factor-β on Follicle-Stimulating Hormone-Induced Differentiation of Cultured Rat Granulosa Cells*

1987 • 161 citations

Transforming growth factor β levels in rat wound chambers

1987 • 161 citations

Binding of Transforming Growth Factor-β to Cell Surface Proteins Varies with Cell Type

1989 • 160 citations

Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factor.

1986 • 159 citations

Intron-exon structure of the human transforming growth factor-β precursor gene

1987 • 159 citations

Transforming growth factor-beta inhibits the in vitro generation of lymphokine-activated killer cells and cytotoxic T cells

1988 • 155 citations

Accumulation, localization, and compartmentation of transforming growth factor beta during endochondral bone development.

1988 • 154 citations

Skeletal tissue and transforming growth factor β

1988 • 151 citations

Type 1 transforming growth factor beta: amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells.

1987 • 147 citations

Transforming Growth Factor-Beta: Selective Increase in Glycosaminoglycan Synthesis by Cultures of Fibroblasts From Patients With Progressive Systemic Sclerosis

1987 • 145 citations

Molecular Repair, Wound Healing, And Carcinogenesis: Tumor Production A Possible Overhealing?

1973 • 139 citations

Subunit structure of a high-affinity receptor for type beta-transforming growth factor. Evidence for a disulfide-linked glycosylated receptor complex.

1985 • 139 citations

Heterodimeric transforming growth factor beta. Biological properties and interaction with three types of cell surface receptors.

1988 • 138 citations

ANTAGONISTIC INTERACTIONS OF TRANSFORMING GROWTH FACTORS IN THE REGULATION OF GRANULOSA CELL DIFFERENTIATION

1986 • 137 citations

The elastogenic effect of recombinant transforming growth factor-beta on porcine aortic smooth muscle cells

1988 • 137 citations

Stimulation by insulin-like growth factors is required for cellular transformation by type beta transforming growth factor.

1985 • 137 citations

Amino acid sequence of the BSC-1 cell growth inhibitor (polyergin) deduced from the nucleotide sequence of the cDNA.

1988 • 134 citations

Increased secretion of type beta transforming growth factor accompanies viral transformation of cells.

1985 • 132 citations

Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes.

1985 • 129 citations

Type beta transforming growth factor is a potent inhibitor of murine megakaryocytopoiesis in vitro

1987 • 129 citations

Agents that increase cAMP accumulation block endothelial c-sis induction by thrombin and transforming growth factor-beta.

1987 • 126 citations

Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells.

1987 • 126 citations

Transforming Growth Factor-β Stimulates Meiotic Maturation of the Rat Oocyte

1988 • 125 citations

Regulation of growth and differentiation of human keratinocytes by type beta transforming growth factor and epidermal growth factor.

1987 • 124 citations

Expression of TGF-beta gene in adult T cell leukemia

1988 • 122 citations

Transforming Growth Factor

2008 • 121 citations

Bi‐functional action of transforming growth factor‐β on DNA synthesis in early passage human fetal fibroblasts

1986 • 121 citations

Membrane binding characteristics of two forms of transforming growth factor-beta.

1987 • 118 citations

Transforming growth factor type β regulation of actin mRNA

1986 • 116 citations

Transforming growth factor β inhibits Leydig cell functions

1987 • 109 citations

Localization of the expression of types I, III, and IV collagen, TGF-β1 and c-fos genes in developing human calvarial bones

1988 • 109 citations

Further studies of the role of transforming growth factor-beta in human B cell function.

1989 • 108 citations

Anchorage‐independent growth of primary rat embryo cells is induced by platelet‐derived growth factor and inhibited by type‐beta transforming growth factor

1986 • 108 citations

Recombinant TGF-β1 is Synthesized as a Two-Component Latent Complex that Shares Some Structural Features with the Native Platelet Latent TGF-β1 Complex

1989 • 108 citations

Type beta transforming growth factor (TGF-β) is a potent stimulator of the basal secretion of follicle stimulating hormone (FSH) in a pituitary monolayer system

1986 • 107 citations

Structure and properties of the cellular receptor for transforming growth factor type beta

1986 • 104 citations

Differential effects of transforming growth factor type beta on the growth and function of adrenocortical cells in vitro.

1986 • 103 citations

Transforming growth factor-β inhibits Leydig cell steroidogenesis in primary culture

1987 • 102 citations

Antibodies to peptide determinants in transforming growth factor .beta. and their applications

1988 • 102 citations

TGF‐β inhibits growth factor‐induced DNA synthesis in hamster fibroblasts without affecting the early mitogenic events

1988 • 99 citations

Transforming Growth Factor Beta

1989 • 98 citations

Transforming growth factor type β (TGF β) inhibits G1 to S transition, but not activation of human B lymphocytes

1987 • 97 citations

Effect of transforming growth factor β on cell proliferation and glycosaminoglycan synthesis by rabbit growth-plate chondrocytes in culture

1988 • 96 citations

Cloning and Sequence Analysis of Simian Transforming Growth Factor-β cDNA

1987 • 95 citations

cDNA cloning of porcine transforming growth factor-beta 1 mRNAs. Evidence for alternate splicing and polyadenylation.

1988 • 95 citations

BSC-1 growth inhibitor transforms a mitogenic stimulus into a hypertrophic stimulus for renal proximal tubular cells: relationship to Na+/H+ antiport activity.

1985 • 94 citations

Stimulation of DNA synthesis in cultured primary human mesothelial cells by specific growth factors

1988 • 94 citations

Bifunctional Role of Transforming Growth Factor-β during Granulosa Cell Development

1987 • 94 citations

Chromosomal mapping of genes for transforming growth factors beta 2 and beta 3 in man and mouse: dispersion of TGF-beta gene family.

1988 • 93 citations

BSC-1 growth inhibitor/type beta transforming growth factor is a strong inhibitor of thymocyte proliferation.

1986 • 92 citations

Biologic mechanisms for the regulation of normal human keratinocyte proliferation and differentiation.

1988 • 90 citations

Stimulation of glycolysis and amino acid uptake in NRK-49F cells by transforming growth factor beta and epidermal growth factor.

1985 • 88 citations

Transforming growth factor beta regulates the inhibitory actions of epidermal growth factor during granulosa cell differentiation.

1986 • 88 citations

Regulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines.

1987 • 86 citations

Opposite and selective effects of epidermal growth factor and human platelet transforming growth factor-beta on the production of secreted proteins by murine 3T3 cells and human fibroblasts.

1986 • 84 citations

Role of Transforming Growth Factor Beta in the Maturation of Human Epidermal Keratinocytes

1988 • 82 citations

Transforming growth factor β: Possible roles in the regulation of normal and leukemic hematopoietic cell growth

1989 • 82 citations

Transforming growth factor β inhibits DNA synthesis in hepatocytes isolated from normal and regenerating rat liver

1987 • 81 citations

Heparin-binding growth factor/prostatropin attenuates inhibition of rat prostate tumor epithelial cell growth by transforming growth factor type beta

1988 • 80 citations

Human platelet alpha granules contain a nonspecific inhibitor of megakaryocyte colony formation: Its relationship to type β transforming growth factor (TGF‐β)

1988 • 78 citations

Interaction of colicin A with phospholipid monolayers and liposomes

1983 • 78 citations

Complementary Deoxyribonucleic Acid Cloning of Bovine Transforming Growth Factor-β1

1987 • 75 citations

The effects of platelet‐derived transforming growth factor β on normal human diploid gingival fibroblasts

1986 • 75 citations

Purification to homogeneity and amino acid sequence analysis of two anionic species of human interleukin 1.

1986 • 73 citations

Inhibition of proliferation of normal, preneoplastic, and neoplastic rat hepatocytes by transforming growth factor-beta.

1987 • 71 citations

Suppression of the EGF-dependent induction of c-myc proto-oncogene expression by transforming growth factor β in a human breast carcinoma cell line

1987 • 70 citations

Immunodetection and modulation of cellular growth with antibodies against native transforming growth factor-beta 1.

1987 • 68 citations

Type beta transforming growth factor affects adrenocortical cell-differentiated functions.

1987 • 68 citations

Sequence of the porcine transforming growth factor-beta precursor

1987 • 66 citations

Appearance of high affinity receptors for type beta transforming growth factor during differentiation of murine embryonal carcinoma cells.

1987 • 65 citations

1,25-Dihydroxyvitamin D3 increases epidermal growth factor receptors and transforming growth factor beta-like activity in a bone-derived cell line.

1987 • 65 citations

Modulation of C-myc by transforming growth factor-β in human colon carcinoma cells

1988 • 64 citations

Nucleotide sequence of chicken transforming growth factor-beta 1 (TGF-β 1)

1988 • 57 citations

Stimulation of glucose uptake by transforming growth factor beta: evidence for the requirement of epidermal growth factor-receptor activation.

1985 • 55 citations

Epstein‐Barr virus mediates a switch in responsiveness to transforming growth factor, type beta, in cells of the B cell lineage

1987 • 55 citations

Bovine adrenocortical cells exhibit high affinity transforming growth factor-beta receptors which are regulated by adrenocorticotropin.

1988 • 55 citations

Recombinant Type 1 Transforming Growth Factor β Precursor Produced in Chinese Hamster Ovary Cells Is Glycosylated and Phosphorylated

1988 • 53 citations

Coupling of TGF-β-induced mitogenesis to G-protein activation in AKR-2B cells

1988 • 52 citations

Transforming growth factor-beta: new chemical forms and new biological roles.

1988 • 50 citations

Inhibition of proliferation of cultured rat liver epithelial cells at specific cell cycle stages by transforming growth factor-β

1987 • 49 citations

Direct regulating effects of transforming growth factor β on the leydig cell steroidogenesis in primary culture

1988 • 46 citations

A new method for high yield purification of type beta transforming growth factor from human platelets

1988 • 46 citations

Evidence for a FSH dependent secretion of a receptor reactive transforming growth factor β-like material by immature sertoli cells in primary culture

1988 • 44 citations

Increased expression of growth factor mRNAs accompanies viral transformation of rodent cells.

1988 • 42 citations

Tyrosine phosphorylation in cells treated with transforming growth factor‐β

1986 • 42 citations

Lysosomal and cytosolic sialidases in rabbit alveolar macrophages: demonstration of increased lysosomal activity after in vivo activation with bacillus Calmette-Guerin

1987 • 34 citations

The Effects of TGFβ on Haemopoietic Cells

1989 • 33 citations

Transforming growth factor type beta 3 maps to human chromosome 14, region q23-q24.

1988 • 31 citations

Recombinant type 1 transforming growth factor beta precursor produced in Chinese hamster ovary cells is glycosylated and phosphorylated.

1988 • 29 citations

Effect of cytokines and growth factors on the expression of elastase activity by human synoviocytes, dermal fibroblasts and rabbit articular chondrocytes

1988 • 27 citations

Enhanced suppression of 1,25(OH)2D3 and intact parathyroid hormone in Graves' disease as compared to toxic nodular goiter

1988 • 21 citations

Isolation and characterization of mink lung epithelial cell mutants resistant to transforming growth factor β

1987 • 16 citations

Deleted Work

1955 • 0 citations