Interleukin 1: An Immunological Perspective

Interleukin 1, a potential regulator of fibroblast proliferation.

1982 • 835 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 742 citations

Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing.

1983 • 701 citations

Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production.

1982 • 665 citations

Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1).

1981 • 614 citations

Muscle Proteolysis Induced by a Circulating Peptide in Patients with Sepsis or Trauma

1983 • 469 citations

Interleukin 1 stimulation of collagenase production by cultured fibroblasts.

1983 • 373 citations

Stimulation by human interleukin 1 of cartilage breakdown and production of collagenase and proteoglycanase by human chondrocytes but not by human osteoblasts in vitro

1984 • 281 citations

Human leukocytic pyrogen: purification and development of a radioimmunoassay.

1977 • 269 citations

Endogenous pyrogens made by rabbit peritoneal exudate cells are identical with lymphocyte-activating factors made by rabbit alveolar macrophages.

1980 • 260 citations

Purification to apparent homogeneity of murine interleukin 1.

1981 • 257 citations

Endogenous Pyrogen Activity in Human Plasma After Exercise

1983 • 256 citations

Amino Acid and Energy Metabolism in Septic and Traumatized Patients

1980 • 234 citations

The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen

1981 • 224 citations

Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.

1978 • 206 citations

Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1.

1983 • 187 citations

Relationship between production and release of lymphocyte-activating factor (interleukin 1) by murine macrophages

1981 • 174 citations

Regulation of macrophage populations. II. Synthesis and expression of Ia antigens by peritoneal exudate macrophages is a transient event.

1981 • 153 citations

Interleukin 1-mediated induction of kappa-light chain synthesis and surface immunoglobulin expression on pre-B cells.

1984 • 134 citations

Phorbol myristic acetate stimulates LAF production by the macrophage cell line, P388D

1978 • 134 citations

Polyclonal stimulation of resting B lymphocytes by antigen-specific T lymphocytes.

1984 • 106 citations

Macrophages and T cells control distinct phases of B cell differentiation in the humoral immune response in vitro.

1980 • 102 citations

Multiple biological activities of a partially purified leukocytic endogenous mediator

1973 • 99 citations

Characterization of Lymphocyte-Activating Factor (LAF) Produced by Human Mononuclear Cells: Biochemical Relationship of High and Low Molecular Weight Forms of LAF

1979 • 88 citations

Synthesis and Secretion of a Mitogenic Protein by Macrophages: Description of a Superinduction Phenomenon

1977 • 87 citations

Production of lymphocyte activating factor in the absence of endogenous pyrogen by rabbit or human leukocytes stimulated by a muramyl dipeptide derivative

1982 • 81 citations

Comparison of Leukocytic Pyrogen and Leukocytic Endogenous Mediator

1977 • 81 citations

Regulation of Lymphocyte-Activating Factor (LAF) Production and Secretion in P388D1 Cells: Identification of High Molecular Weight Precursors of LAF

1979 • 74 citations

Purification and partial biochemical characterization of normal human interleukin 1.

1984 • 68 citations

Coordinate production by a T cell hybridoma of gamma interferon and three other lymphokine activities: multiple activities of a single lymphokine?

1983 • 56 citations

Antigen presentation in the murine T lymphocyte proliferative response. II. Ir‐GAT‐controlled T lymphocyte responses require antigen‐presenting cells from a high responder donor

1978 • 55 citations

Preparation of goat antibodies against interleukin 1: use of an immunoadsorbent to purify interleukin 1

1984 • 54 citations

MHC‐Restricted T Cell Activation: Analysis with T Cell Hybridomas

1983 • 53 citations

Monoclonal antibody against human interleukin 2 (IL 2). I. Purification of IL 2 for the production of monoclonal antibodies.

1982 • 49 citations

Mechanisms of action of "lymphocyte-activating factor" (LAF). III. Evidence that LAF acts on stimulated lymphocytes by raising cyclic GMP in G1.

1978 • 47 citations

Defective Macrophage Function in a Patient with Common Variable Immunodeficiency

1982 • 46 citations

Interleukin 1 production by a human acute monocytic leukemia cell line

1983 • 45 citations

Calcium ionophore (A23187) increases interleukin 1 (IL-1) production by human peripheral blood monocytes and interacts synergistically with IL-1 to augment Concanavalin A stimulated thymocyte proliferation

1985 • 43 citations

Induction of interleukin 1 messenger RNA and translation in oocytes.

1984 • 27 citations

Pyrogen release from human synovial exudate cells.

1968 • 22 citations

Heterogeneity of rabbit endogenous pyrogens is not attributable to glycosylated variants of a single polypeptide chain

1981 • 12 citations

Deleted Work

1955 • 0 citations