Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Prediction of protein antigenic determinants from amino acid sequences.

1981 • 3,715 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene

1985 • 1,804 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1984 • 1,153 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3

1986 • 823 citations

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1986 • 795 citations

High efficiency polyoma DNA transfection of chloroquine treated cells

1983 • 711 citations

Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas.

1986 • 701 citations

Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

1977 • 695 citations

Speculations on RNA splicing

1981 • 639 citations

A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.

1985 • 607 citations

Functional role for c-myc in mitogenic response to platelet-derived growth factor

1984 • 578 citations

Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation

1986 • 577 citations

Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression.

1986 • 516 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas

1983 • 504 citations

α-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences

1985 • 498 citations

Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation.

1986 • 468 citations

Expression of the c- fos Gene and of an fos -Related Gene Is Stimulated by Platelet-Derived Growth Factor

1984 • 445 citations

Efficient infection of monkey cells with DNA of simian virus 40.

1981 • 419 citations

Human CSF-1: Molecular Cloning and Expression of 4-kb cDNA Encoding the Human Urinary Protein

1987 • 381 citations

Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells.

1987 • 381 citations

TGF-β inhibition of endothelial cell proliferation: Alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression

1987 • 344 citations

Structural analysis of the sequence coding for an inducible 26‐kDa protein in human fibroblasts

1986 • 343 citations

Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes.

1986 • 335 citations

Inducible binding of a factor to the c-fos enhancer

1986 • 310 citations

An immunoglobulin heavy-chain gene is formed by at least two recombinational events

1980 • 306 citations

Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A.

1986 • 293 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells

1985 • 263 citations

Interleukin-2 Induction of T-Cell G ₁ Progression and c- myb Expression

1986 • 248 citations

The statistical distribution of nucleic acid similarities

1985 • 206 citations

Identification of a Transcriptional Enhancer Element Upstream from the Proto-Oncogene fos

1985 • 171 citations

Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factor.

1986 • 159 citations

Expression of cell-cycle-dependent genes in phytohemagglutinin-stimulated human lymphocytes.

1985 • 149 citations

Transforming viruses directly reduce the cellular growth requirement for a platelet derived growth factor

1978 • 134 citations

Multiple Protein-Binding Sites in the 5′-Flanking Region Regulate c-fos Expression

1986 • 133 citations

The effect of LPS on expression of the early "competence" genes JE and KC in murine peritoneal macrophages.

1987 • 132 citations

Biological activities of v-myc and rearranged c-myc oncogenes in rat fibroblast cells in culture.

1984 • 132 citations

Transcriptional activation of the translocated c-myc oncogene in mouse plasmacytomas: Similar RNA levels in tumor and proliferating normal cells

1984 • 116 citations

Potentiation of growth factor activity by exogenous c-myc expression.

1986 • 99 citations

Cloning and characterization of a novel T cell activation gene.

1987 • 88 citations

Transformation of mammalian fibroblasts and macrophages in vitro by a murine retrovirus encoding an avian v-myc oncogene.

1984 • 84 citations

Platelet-derived growth factor-inducible genes respond differentially to at least two distinct intracellular second messengers.

1987 • 84 citations

Antisense RNA of Proto-Oncogene c-fos Blocks Renewed Growth of Quiescent 3T3 Cells

1987 • 70 citations

Structural homologies among the hemopoietins.

1986 • 49 citations

beta-Interferon alters the pattern of proteins secreted from quiescent and platelet-derived growth factor-treated BALB/c-3T3 cells.

1985 • 48 citations

A Cell-Cycle Constraint on the Regulation of Gene Expression by Platelet-Derived Growth Factor

1987 • 44 citations

Differential Responsiveness of myc- and ras-Transfected Cells to Growth Factors: Selective Stimulation of myc-Transfected Cells by Epidermal Growth Factor

1986 • 29 citations