Epidermal growth factor

Epidermal Growth Factor

1979 • 2,964 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

Isolation of a Mouse Submaxillary Gland Protein Accelerating Incisor Eruption and Eyelid Opening in the New-born Animal

1962 • 2,192 citations

Epidermal growth factor.

1990 • 1,645 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

RECEPTORS FOR EPIDERMAL GROWTH FACTOR AND OTHER POLYPEPTIDE MITOGENS

1987 • 1,274 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Isolation and structure of urogastrone and its relationship to epidermal growth factor

1975 • 751 citations

PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM

1960 • 692 citations

Nerve growth factor receptors on human melanoma cells in culture.

1977 • 670 citations

Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

1978 • 647 citations

The retrograde axonal transport of nerve growth factor

1974 • 598 citations

Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431.

1978 • 578 citations

Mouse prepro-epidermal growth factor synthesis by the kidney and other tissues

1985 • 568 citations

Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine

1980 • 539 citations

The Primary Structure of Epidermal Growth Factor

1972 • 533 citations

Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor.

1979 • 530 citations

Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431.

1979 • 528 citations

Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor

1983 • 520 citations

Human epidermal growth factor: isolation and chemical and biological properties.

1975 • 499 citations

Structure of a Mouse Submaxillary Messenger RNA Encoding Epidermal Growth Factor and Seven Related Proteins

1983 • 448 citations

Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro

1978 • 448 citations

Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts

1975 • 432 citations

The stimulation of epidermal proliferation by a specific protein (EGF)

1965 • 421 citations

Human epidermal growth factor and the proliferation of human fibroblasts

1976 • 403 citations

Pituitary Extracts and Steroid Hormones in the Control of 3T3 Cell Growth

1973 • 387 citations

Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells

1976 • 374 citations

lin-12, a nematode homeotic gene, is homologous to a set of mammalian proteins that includes epidermal growth factor

1985 • 369 citations

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

1978 • 358 citations

Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts.

1984 • 357 citations

Epidermal Growth Factor: Receptors in Human Fibroblasts and Modulation of Action by Cholera Toxin

1973 • 328 citations

The Stimulation of Epidermal Keratinization by a Protein Isolated from the Submaxillary Gland of the Mouse**From the Department of Biochemistry and the Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee.

1963 • 310 citations

Hormone receptor topology and dynamics: Morphological analysis using ferritin-labeled epidermal growth factor

1979 • 254 citations

Epidermal Growth Factor

1973 • 233 citations

Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A431 cells.

1982 • 232 citations

Epidermal Growth Factor

1972 • 214 citations

Epidermal Growth Factor: Chemical and Biological Characterization,

1974 • 207 citations

Specific radiolabeling of a cell surface receptor for epidermal growth factor.

1977 • 204 citations

Epidermal Growth Factor: Identification of a New Hormone in Human Urine

1975 • 186 citations

Epidermal growth factor, its receptor, and related proteins

1986 • 186 citations

Purification and characterization of epidermal growth factor receptor/protein kinase from normal mouse liver.

1982 • 183 citations

Recent Studies on the Chemistry and Biology of Epidermal Growth Factor

1974 • 169 citations

Characterization by electrophoresis of epidermal growth factor stimulated phosphorylation using A-431 membranes

1980 • 153 citations

Identification of epidermal growth factor receptors in a hyperproducing human epidermoid carcinoma cell line.

1979 • 153 citations

Vaccinia virus-infected cells release a novel polypeptide functionally related to transforming and epidermal growth factors.

1985 • 146 citations

Interaction of Epidermal Growth Factor (EGF) with Cultured Fibroblasts

1975 • 146 citations

Proteolytic cleavage of epidermal growth factor receptor. A Ca2+-dependent, sulfhydryl-sensitive proteolytic system in A431 cells.

1982 • 138 citations

Purified EGF receptor–kinase interacts specifically with antibodies to Rous sarcoma virus transforming protein

1981 • 130 citations

Influence of lectins on the binding of 125I-labeled EGF to human fibroblasts

1977 • 85 citations

Characterization of the interaction of 5'-p-fluorosulfonylbenzoyl adenosine with the epidermal growth factor receptor/protein kinase in A431 cell membranes.

1983 • 83 citations

Isolation of the human placenta receptor for epidermal growth factor-urogastrone

1979 • 80 citations

Anti-pp60src antibodies are substrates for EGF-stimulated protein kinase

1981 • 78 citations

Calcium facilitates endogenous proteolysis of the EGF receptor-kinase

1982 • 48 citations

Biosynthesis and metabolic degradation of receptors for epidermal growth factor

1986 • 47 citations