Interleukin 1 can act as a B-cell growth and differentiation factor.

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 921 citations

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

1984 • 820 citations

Biological Activity of Recombinant Human Interleukin-2 Produced in Escherichia coli

1984 • 600 citations

Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor.

1984 • 438 citations

Regulation of B-Cell Growth and Differentiation by Soluble Factors

1983 • 432 citations

Two distinct factors are required for induction of T-cell growth

1980 • 416 citations

Characterization of lymphocyte-activating factor (LAF) produced by the macrophage cell line, P388D1. I. Enhancement of LAF production by activated T lymphocytes.

1978 • 379 citations

Factors Affecting B-Cell Growth and Differentiation

1985 • 354 citations

Interleukin-induced increase in Ia expression by normal mouse B cells.

1984 • 293 citations

Purification to apparent homogeneity of murine interleukin 1.

1981 • 257 citations

Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays.

1983 • 204 citations

B-cell stimulatory factor 1 activates resting B cells.

1985 • 201 citations

Antigen-induced T cell-replacing factor (TRF). III. Establishment of T cell hybrid clone continuously producing TRF and functional analysis of released TRF.

1980 • 166 citations

B cell activation: Three steps and their variations

1984 • 130 citations

B Cell Growth and Differentiation Factors

1984 • 126 citations

B-cell growth factor (B-cell growth factor I or B-cell-stimulating factor, provisional 1) is a differentiation factor for resting B cells and may not induce cell growth.

1985 • 118 citations

BCGFII activity on activated B cells of a purified murine T cell-replacing factor (TRF) from a T cell hybridoma (B151K12).

1985 • 100 citations

B Cell Growth and Differentiation Factors and Mechanism of B Cell Activation

1984 • 99 citations

Single cell studies on the antibody-forming potential of fractionated, hapten-specific B lymphocytes.

1976 • 87 citations

The Synergism of Aecessory Cells and of Soluble a‐Factors Derived from Them in the Activation of B Cells to Proliferation

1984 • 78 citations

B cell helper factors. II. Synergy among three helper factors in the response of T cell- and macrophage-depleted B cells.

1982 • 78 citations

Level of mIa expression on mitogen-stimulated murine B lymphocytes is dependent on position in cell cycle.

1983 • 75 citations

Role of BCGFII in the differentiation to antibody secretion normal and tumor B cells.

1985 • 71 citations

Proliferation and differentiation of single hapten-specific B lymphocytes is promoted by T-cell factor(s) distinct from T-cell growth factor.

1982 • 63 citations

Human interleukin 2 can promote the growth and differentiation of single hapten-specific B cells in the presence of specific antigen.

1984 • 55 citations

Preparation of goat antibodies against interleukin 1: use of an immunoadsorbent to purify interleukin 1

1984 • 54 citations

A reappraisal of "T-independent" antigens. I. Effect of lymphokines on the response of single adult hapten-specific B lymphocytes.

1984 • 52 citations

Sequential use of hapten‐gelatin fractionation and fluorescence‐activated cell sorting in the enrichment of hapten‐specific B lymphocytes

1978 • 48 citations

Analysis of true anti-hapten cytotoxic clones in limit dilution microcultures after correction for "anti-self" activity: precursor frequencies, Ly-2 and Thy-1 phenotype, specificity, and statistical methods.

1983 • 47 citations

Evidence for two distinct activation states available to B lymphocytes.

1984 • 38 citations

Interleukin 1 induces proliferation in two distinct B cell subpopulations responsive to two different murine B cell growth factors.

1984 • 35 citations

A high-efficiency cloning system for single hapten-specific B lymphocytes that is suitable for assay of putative growth and differentiation factors.

1985 • 34 citations

Antibody production by single, hapten-specific B lymphocytes: an antigen-driven cloning system free of filler or accessory cells.

1981 • 32 citations

Single cell studies on hapten-specific B lymphocytes: differential cloning efficiency of cells of various sizes.

1983 • 17 citations