Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

USE OF GLUCOSE OXIDASE, PEROXIDASE, AND O-DIANISIDINE IN DETERMINATION OF BLOOD AND URINARY GLUCOSE

1957 • 1,808 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities.

1987 • 1,345 citations

A peroxidase-coupled method for the colorimetric determination of serum triglycerides.

1983 • 1,327 citations

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

1989 • 1,183 citations

Interleukin-1 and Its Biologically Related Cytokines

1989 • 1,180 citations

Production of hybridoma growth factor by human monocytes

1987 • 1,133 citations

ASSOCIATION BETWEEN TUMOUR NECROSIS FACTOR IN SERUM AND FATAL OUTCOME IN PATIENTS WITH MENINGOCOCCAL DISEASE

1987 • 1,108 citations

Human tumor necrosis factor. Production, purification, and characterization.

1985 • 922 citations

Tumor Necrosis Factor and Interleuktn-1 in the Serum of Children with Severe Infectious Purpura

1988 • 735 citations

Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits.

1988 • 603 citations

Peptide Regulatory Factors

1989 • 498 citations

Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog.

1987 • 425 citations

On the fragmentation of monoclonal IgG1, IgG2a, and IgG2b from BALB/c mice.

1983 • 417 citations

Endotoxemia elicits increased circulating beta 2-IFN/IL-6 in man.

1989 • 323 citations

Interleukin 6, the third mediator of acute‐phase reaction, modulates hepatic protein synthesis in human and mouse. Comparison with interleukin 1 β and tumor necrosis factor‐α

1988 • 287 citations

Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins

1989 • 261 citations

Interleukin 1 potentiates the lethal effect of tumor necrosis factor alpha/cachectin in mice.

1988 • 247 citations

Multiple forms of IFN-beta 2/IL-6 in serum and body fluids during acute bacterial infection.

1989 • 244 citations

Monoclonal antibodies to human recombinant interleukin 1 (IL 1)beta: quantitation of IL 1 beta and inhibition of biological activity.

1987 • 115 citations

Response of the subhuman primate in gram-negative septicemia induced by live Escherichia coli.

1971 • 9 citations