Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels.

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

Depletion of intracellular calcium stores activates a calcium current in mast cells

1992 • 1,748 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

Capacitative calcium entry revisited

1990 • 1,499 citations

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1991 • 1,054 citations

Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester

1985 • 753 citations

Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.

1993 • 752 citations

Calcium release‐activated calcium current in rat mast cells.

1993 • 729 citations

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1987 • 676 citations

SIGNAL TRANSMISSION BETWEEN THE PLASMA MEMBRANE AND NUCLEUS OF T LYMPHOCYTES

1994 • 634 citations

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1994 • 523 citations

The Inositol Phosphate-Calcium Signaling System in Nonexcitable Cells

1993 • 505 citations

Potassium and Calcium Channels in Lymphocytes

1995 • 488 citations

Characterization of antigen receptor response elements within the interleukin-2 enhancer.

1988 • 451 citations

A voltage‐gated potassium channel in human T lymphocytes.

1985 • 403 citations

Receptor-activated Ca2+ influx: how many mechanisms for how many channels?

1994 • 403 citations

Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells.

1989 • 402 citations

GENETICS OF SOMATIC MAMMALIAN CELLS

1956 • 378 citations

Rapid inactivation of depletion-activated calcium current (ICRAC) due to local calcium feedback.

1995 • 370 citations

Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane

1994 • 305 citations

Dual Calcium Ion Regulation of Calcineurin by Calmodulin and Calcineurin B

1994 • 303 citations

Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.

1990 • 292 citations

Agonist‐stimulated divalent cation entry into single cultured human umbilical vein endothelial cells.

1990 • 280 citations

The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency.

1994 • 256 citations

Genetics of somatic mammalian cells. IX. Quantitation of mutagenesis by physical and chemical agents

1969 • 245 citations

Intracellular calcium dependence of gene expression in single T lymphocytes.

1994 • 244 citations

Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation.

1993 • 242 citations

Slow Calcium-dependent Inactivation of Depletion-activated Calcium Current. STORE-DEPENDENT AND -INDEPENDENT MECHANISMS

1995 • 234 citations

Activation of recombinant trp by thapsigargin in Sf9 insect cells

1994 • 226 citations

IP ₃ Receptor: Localization to Plasma Membrane of T Cells and Cocapping with the T Cell Receptor

1992 • 213 citations

Persistent intracellular calcium pool depletion by thapsigargin and its influence on cell growth.

1991 • 206 citations

Signaling between intracellular Ca2+ stores and depletion-activated Ca2+ channels generates [Ca2+]i oscillations in T lymphocytes.

1994 • 181 citations

Early Signal Transduction by the Antigen Receptor Without Commitment to T Cell Activation

1988 • 169 citations

Calcium influx and its control by calcium release

1993 • 167 citations

Non-specific effects of calcium entry antagonists in mast cells

1994 • 164 citations

Ca2+ and Mn2+ influx through receptor-mediated activation of nonspecific cation channels in mast cells.

1993 • 154 citations

Characterization of Antigen Receptor Response Elements within the Interleukin-2 Enhancer

1988 • 143 citations

Calcium fluxes in T lymphocytes.

1992 • 133 citations

Calcium channels activated by depletion of internal calcium stores in A431 cells

1994 • 131 citations

Ca(2+)-activated K+ channels in human leukemic T cells.

1992 • 128 citations

Activation of Ca2+ current in Jurkat T cells following the depletion of Ca2+ stores by microsomal Ca(2+)-ATPase inhibitors.

1994 • 123 citations

Inhibition by SK&F 96365 of Ca²⁺ current, IL‐2 production and activation in T lymphocytes

1994 • 111 citations

Calcium oscillations in human T and natural killer cells depend upon membrane potential and calcium influx.

1993 • 110 citations

Ca²⁺ influx in human T lymphocytes is induced independently of inositol phosphate production by mobilization of intracellular Ca²⁺ stores. A study with the Ca²⁺ endoplasmic reticulum‐ATPase inhibitor thapsigargin

1990 • 106 citations

Inhibition of voltage‐gated Ca ²⁺ entry into GH ₃ and chromaffin cells by imidazole antimycotics and other cytochrome P450 blockers

1992 • 98 citations

The role of intracellular Ca2+ in the regulation of the plasma membrane Ca2+ permeability of unstimulated rat lymphocytes

1991 • 82 citations

Regulation of Ca2+ influx during mitosis: Ca2+ influx and depletion of intracellular Ca2+ stores are coupled in interphase but not mitosis.

1991 • 81 citations

Isolation of mutant T lymphocytes with defects in capacitative calcium entry

1995 • 65 citations

Na+/Ca2+ exchange-mediated calcium entry in human lymphocytes.

1994 • 63 citations

Flow cytometric analysis of murine splenic B lymphocyte cytosolic free calcium response to anti‐IgM and anti‐IgD

1987 • 62 citations

Ionomycin activates electrogenic Ca2+ influx in rat thymic lymphocytes

1993 • 58 citations

Evidence for two types of internal Ca2+ stores in canine mesenteric artery with different refilling mechanisms

1992 • 51 citations

Control of plasma-membrane Ca2+ entry by the intracellular Ca2+ stores. Kinetic evidence for a short-lived mediator

1992 • 48 citations

At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor.

1988 • 42 citations

Calcium influx and intracellular calcium release in anti-CD3 antibody-stimulated and thapsigargin-treated human T lymphoblasts

1991 • 41 citations

Complete nucleotide sequence and characterization of the 5'-flanking region of mammalian elongation factor 2 gene.

1988 • 37 citations

Characterization of Ca2+ and K+ currents in the human Jurkat T cell line: effects of phytohaemagglutinin.

1989 • 27 citations

A voltage‐gated calcium channel is linked to the antigen receptor in Jurkat T lymphocytes

1992 • 26 citations

Two independently regulated Ca2+ entry mechanisms coexist in Jurkat T cells during T cell receptor antigen activation

1993 • 22 citations

Distinct Mechanisms for Ca2+ Entry Induced by OKT3 and Ca2+ Depletion in Jurkat T Cells

1995 • 16 citations

Isolation and characterization of membrane potential changes associated with release of calcium from intracellular stores in rat thymic lymphocytes

1994 • 15 citations