Glutamate receptors in the mammalian central nervous system

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Cloned Glutamate Receptors

1994 • 3,989 citations

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans

1994 • 3,182 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Recent advances in the phencyclidine model of schizophrenia

1991 • 2,886 citations

Delayed neuronal death in the gerbil hippocampus following ischemia

1982 • 2,856 citations

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1984 • 2,822 citations

Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid

1993 • 2,625 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

The metabotropic glutamate receptors: Structure and functions

1995 • 2,269 citations

The Role of Glutamate Neurotoxicity in Hypoxic-Ischemic Neuronal Death

1990 • 2,204 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

1986 • 1,842 citations

Excitatory amino acid neurotoxicity and neurodegenerative disease

1990 • 1,781 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory

1996 • 1,750 citations

Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage

1988 • 1,745 citations

Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy

1985 • 1,730 citations

The physiology of excitatory amino acids in the vertebrate central nervous system

1987 • 1,718 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activation

1995 • 1,636 citations

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

1991 • 1,465 citations

A Family of AMPA-Selective Glutamate Receptors

1990 • 1,453 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

Synaptic plasticity: LTP and LTD

1994 • 1,301 citations

Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain

1996 • 1,272 citations

Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS

1995 • 1,239 citations

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1990 • 1,234 citations

Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists

1988 • 1,202 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

1992 • 1,077 citations

The Time Course of Glutamate in the Synaptic Cleft

1992 • 1,071 citations

Excitotoxity and the NMDA receptor

1987 • 1,053 citations

Cloning by functional expression of a member of the glutamate receptor family

1989 • 1,009 citations

Light and electron immunocytochemical localization of AMPA‐selective glutamate receptors in the rat brain

1992 • 988 citations

Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.

1993 • 978 citations

Permeation and block of N‐methyl‐D‐aspartic acid receptor channels by divalent cations in mouse cultured central neurones.

1987 • 934 citations

Molecular Cloning and Functional Expression of Glutamate Receptor Subunit Genes

1990 • 925 citations

Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice

1994 • 884 citations

The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels

1993 • 882 citations

A family of metabotropic glutamate receptors

1992 • 873 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

Contrasting properties of two forms of long-term potentiation in the hippocampus

1995 • 839 citations

Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following c fibre stimulation.

1987 • 836 citations

Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit

1995 • 832 citations

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.

1993 • 828 citations

Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors

1984 • 824 citations

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

1992 • 814 citations

The role of divalent cations in the N‐methyl‐D‐aspartate responses of mouse central neurones in culture.

1988 • 810 citations

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

1992 • 805 citations

Metabotropic glutamate receptors in brain function and pathology

1993 • 799 citations

Identification of a Site in Glutamate Receptor Subunits That Controls Calcium Permeability

1991 • 774 citations

An Adenovirus Vector for Gene Transfer into Neurons and Glia in the Brain

1993 • 746 citations

Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells

1978 • 745 citations

A new type of glutamate receptor linked to inositol phospholipid metabolism

1987 • 743 citations

Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

1993 • 736 citations

Control of Kinetic Properties of AMPA Receptor Channels by Nuclear RNA Editing

1994 • 735 citations

Glutamate stimulates inositol phosphate formation in striatal neurones

1985 • 734 citations

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1

1994 • 730 citations

Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate

1993 • 724 citations

Developmental changes in distribution of NMDA receptor channel subunit mRNAs

1992 • 718 citations

Metabotropic glutamate receptors: Synaptic transmission, modulation, and plasticity

1994 • 713 citations

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

1993 • 695 citations

Glutamate activates multiple single channel conductances in hippocampal neurons

1987 • 691 citations

Evidence for involvement ofN-methylaspartate receptors in ‘wind-up’ of class 2 neurones in the dorsal horn of the rat

1987 • 666 citations

Differences in Ca2+ permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression

1994 • 661 citations

RNA editing of AMPA receptor subunit GluR-B: A base-paired intron-exon structure determines position and efficiency

1993 • 657 citations

Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development

1990 • 646 citations

Structure and function of the NMDA receptor channel

1995 • 645 citations

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

1991 • 638 citations

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice

1994 • 607 citations

A Molecular Determinant for Submillisecond Desensitization in Glutamate Receptors

1994 • 607 citations

Zinc potentiates agonist-lnduced currents at certain splice variants of the NMDA receptor

1993 • 605 citations

Impaired Hippocampal Representation of Space in CA1-Specific NMDAR1 Knockout Mice

1996 • 594 citations

Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia

1990 • 589 citations

Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4

1993 • 585 citations

Kainic acid as a tool for the study of temporal lobe epilepsy

1981 • 584 citations

Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A

1993 • 581 citations

Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block

1995 • 571 citations

Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents

1990 • 570 citations

Responses of Single Dorsal Cord Cells to Peripheral Cutaneous Unmyelinated Fibres

1965 • 564 citations

Early-Onset Epilepsy and Postnatal Lethality Associated with an Editing-Deficient GluR-B Allele in Mice

1995 • 564 citations

Glutamate-operated channels: Developmentally early and mature forms arise by alternative splicing

1991 • 560 citations

Neurologic Sequelae of Domoic Acid Intoxication Due to the Ingestion of Contaminated Mussels

1990 • 555 citations

Kainate receptors mediate a slow postsynaptic current in hippocampal CA3 neurons

1997 • 551 citations

Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluRl, in transfected CHO cells

1992 • 539 citations

The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits

1992 • 537 citations

The ontogeny of excitatory amino acid receptors in rat forebrain—I.N-methyl-d-aspartate and quisqualate receptors

1990 • 526 citations

AMPA receptor subunits expressed by single purkinje cells

1992 • 524 citations

Cloning, Expression, and Gene Structure of a G Protein-Coupled Glutamate Receptor from Rat Brain

1991 • 524 citations

Anatomical distributions of four pharmacologically distinct 3H-L-glutamate binding sites

1983 • 522 citations

Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing

1992 • 521 citations

7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex.

1988 • 517 citations

Analysis of excitatory synaptic action in pyramidal cells using whole‐cell recording from rat hippocampal slices.

1990 • 505 citations

Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones.

1990 • 498 citations

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

1994 • 496 citations

Enhanced LTP in Mice Deficient in the AMPA Receptor GluR2

1996 • 494 citations

Impairment of Suckling Response, Trigeminal Neuronal Pattern Formation, and Hippocampal LTD in NMDA Receptor ε2 Subunit Mutant Mice

1996 • 486 citations

Single-Channel Properties of Recombinant AMPA Receptors Depend on RNA Editing, Splice Variation, and Subunit Composition

1997 • 484 citations

The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography

1982 • 481 citations

Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice

1994 • 479 citations

Dendritic glutamate receptor channels in rat hippocampal CA3 and CA1 pyramidal neurons.

1995 • 478 citations

Specific deficit of the ON response in visual transmission by targeted disruption of the mGIuR6 gene

1995 • 474 citations

Desensitization of AMPA receptors upon multiquantal neurotransmitter release

1993 • 471 citations

Molecular Determinants of Agonist Discrimination by NMDA Receptor Subunits: Analysis of the Glutamate Binding Site on the NR2B Subunit

1997 • 470 citations

Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors

1997 • 469 citations

Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction.

1994 • 466 citations

Suppression by glutamate of cGMP-activated conductance in retinal bipolar cells

1990 • 465 citations

A complex mosaic of high-affinity kainate receptors in rat brain

1993 • 464 citations

Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells

1991 • 461 citations

AMPA and kainate receptors

1995 • 460 citations

Glutamate receptor desensitization and its role in synaptic transmission

1989 • 459 citations

Determinants of ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: Diversity by RNA editing

1993 • 453 citations

Coupling of Inositol Phospholipid Metabolism with Excitatory Amino Acid Recognition Sites in Rat Hippocampus

1986 • 444 citations

Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents

1993 • 440 citations

The glycine site of the NMDA receptor — five years on

1993 • 440 citations

Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes.

1995 • 440 citations

Control by Asparagine Residues of Calcium Permeability and Magnesium Blockade in the NMDA Receptor

1992 • 437 citations

Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters

1990 • 436 citations

Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices.

1992 • 435 citations

The activation of inositol phospholipid metabolism as a signal- transducing system for excitatory amino acids in primary cultures of cerebellar granule cells

1986 • 431 citations

Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus.

1991 • 431 citations

Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

1994 • 424 citations

Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells

1994 • 422 citations

Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons

1987 • 420 citations

Glutamate receptor channels in rat DRG neurons: Activation by kainate and quisqualate and blockade of desensitization by con A

1990 • 420 citations

N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1

1994 • 419 citations

The action of N‐methyl‐D‐aspartic acid on mouse spinal neurones in culture.

1985 • 417 citations

The synaptic activation of kainate receptors

1997 • 417 citations

Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain

1993 • 415 citations

Calcium-Permeable AMPA-Kainate Receptors in Fusiform Cerebellar Glial Cells

1992 • 413 citations

A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation

1994 • 405 citations

Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone

1996 • 403 citations

Presynaptic Calcium Current Modulation by a Metabotropic Glutamate Receptor

1996 • 403 citations

NMDA channel behavior depends on agonist affinity

1992 • 401 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.

1992 • 399 citations

Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices

1990 • 396 citations

Ion transport through pores: A rate-theory analysis

1973 • 392 citations

Kainate receptor gene expression in the developing rat brain

1994 • 390 citations

Regulation of glutamate release by presynaptic kainate receptors in the hippocampus

1996 • 383 citations

Mutational analysis of the glycine-binding site of the NMDA receptor: Structural similarity with bacterial amino acid-binding proteins

1994 • 381 citations

Cloning of a putative glutamate receptor: A low affinity kainate-binding subunit

1992 • 379 citations

Intracellular spermine confers rectification on rat calcium‐permeable AMPA and kainate receptors.

1995 • 369 citations

Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate

1993 • 369 citations

Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons

1995 • 366 citations

The use of fura-2 for estimating ca buffers and ca fluxes

1995 • 364 citations

The permeability of the endplate channel to organic cations in frog muscle.

1980 • 362 citations

Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat.

1997 • 362 citations

Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells

1994 • 361 citations

GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses

1993 • 359 citations

Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb

1993 • 355 citations

Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation

1992 • 354 citations

Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1

1995 • 354 citations

Subunit composition at the single-cell level explains functional properties of a glutamate-gated channel

1994 • 351 citations

Olfactory Recognition: A Simple Memory System

1990 • 349 citations

Amelioration of negative symptoms in schizophrenia by glycine

1994 • 349 citations

Molecular mechanisms controlling calcium entry through AMPA-type glutamate receptor channels

1995 • 348 citations

Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C.

1993 • 347 citations

AMPA Receptor Flip/Flop Mutants Affecting Deactivation, Desensitization, and Modulation by Cyclothiazide, Aniracetam, and Thiocyanate

1996 • 343 citations

Impairment of Hippocampal Mossy Fiber LTD in Mice Lacking mGluR2

1996 • 342 citations

Activation of metabotropic glutamate receptor type 2/3 suppresses transmission at rat hippocampal mossy fibre synapses.

1996 • 341 citations

The distribution of glutamate receptors in cultured rat hippocampal neurons: Postsynaptic clustering of AMPA selective subunits

1993 • 340 citations

A glutamate receptor channel with high affinity for domoate and kainate.

1992 • 336 citations

Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus

1990 • 332 citations

Facilitation of glutamate receptors enhances memory.

1994 • 331 citations

A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb

1995 • 328 citations

Functional Comparison of <scp>d</scp>‐Serine and Glycine in Rodents: The Effect on Cloned NMDA Receptors and the Extracellular Concentration

1995 • 327 citations

A cure for wind up: NMDA receptor antagonists as potential analgesics

1990 • 327 citations

Histological and ultrastructural localization of the kainate receptor subunits, KA2 and GluR6/7, in the rat nervous system using selective antipeptide antibodies

1994 • 325 citations

NMDA-receptor channel diversity in the developing cerebellum

1994 • 325 citations

A quantitative description of NMDA receptor-channel kinetic behavior

1990 • 323 citations

Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes

1994 • 323 citations

NMDA receptors: from genes to channels

1996 • 319 citations

Three-dimensional structures of the periplasmic lysine/arginine/ornithine-binding protein with and without a ligand

1993 • 313 citations

Piracetam and other structurally related nootropics

1994 • 312 citations

Micromolar L-2-amino-4-phosphonobutyric acid selectively inhibits perforant path synapses from lateral entorhinal cortex

1981 • 307 citations

Ca2+ permeability of unedited and edited versions of the kainate selective glutamate receptor GluR6.

1993 • 304 citations

Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam.

1990 • 303 citations

MOLECULAR GENETIC ANALYSIS OF SYNAPTIC PLASTICITY, ACTIVITY-DEPENDENT NEURAL DEVELOPMENT, LEARNING, AND MEMORY IN THE MAMMALIAN BRAIN

1997 • 299 citations

Cloning and expression of the ε4 subunit of the NMDA receptor channel

1992 • 296 citations

Cyclothiazide differentially modulates desensitization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor splice variants.

1994 • 295 citations

Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop

1995 • 293 citations

Cloning, expression and modulation of a mouse NMDA receptor subunit

1992 • 291 citations

Kinetics and mechanism of reactions of main group metal ions with biological carriers

1969 • 290 citations

Anatomic correlation of NMDA and 3H-TCP-labeled receptors in rat brain

1988 • 284 citations

Kainate binding sites in the hippocampal mossy fibers: Localization and plasticity

1987 • 280 citations

Block of native Ca(2+)‐permeable AMPA receptors in rat brain by intracellular polyamines generates double rectification.

1995 • 276 citations

Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1

1995 • 275 citations

Antibodies inactivating mGluR1 metabotropic glutamate receptor block long-term depression in cultured Purkinje cells

1994 • 274 citations

Quisqualate receptors are specifically involved in cerebellar synaptic plasticity

1987 • 273 citations

Unraveling the modular design of glutamate-gated ion channels

1995 • 272 citations

Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices.

1992 • 272 citations

Excitatory amino acid receptors in hippocampal neurons: Kainate fails to desensitize them

1986 • 271 citations

3,5‐Dihydroxyphenylglycine Is a Highly Selective Agonist for Phosphoinositide‐Linked Metabotropic Glutamate Receptors in the Rat Hippocampus

1994 • 270 citations

Activation and desensitization of glutamate-activated channels mediating fast excitatory synaptic currents in the visual cortex

1992 • 268 citations

Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters

1994 • 266 citations

Identification by mutagenesis of a Mg2+ -block site of the NMDA receptor channel

1992 • 264 citations

Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors

1992 • 261 citations

Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats

1991 • 253 citations

Modulation of excitatory synaptic transmission by drugs that reduce desensitization at AMPA/kainate receptors

1991 • 252 citations

Presynaptic glutamate receptors depress excitatory monosynaptic transmission between mouse hippocampal neurones.

1990 • 249 citations

The primary afferent depolarizing action of kainate in the rat

1986 • 244 citations

A single amino acid determines the subunit-specific spider toxin block of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor channels.

1993 • 243 citations

Modulation of the Time Course of Fast EPSCs and Glutamate Channel Kinetics by Aniracetam

1991 • 242 citations

Different glutamate receptor channels mediate fast excitatory synaptic currents in inhibitory and excitatory cortical neurons

1993 • 242 citations

The N-methyl-D-aspartate antagonist, MK-801, fails to protect against neuronal damage caused by transient, severe forebrain ischemia in adult rats

1991 • 239 citations

Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3

1995 • 238 citations

Quisqualate Activates a Rapidly Inactivating High Conductance Ionic Channel in Hippocampal Neurons

1989 • 237 citations

Synaptic strengthening through activation of Ca2+ -permeable AMPA receptors

1996 • 236 citations

Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.

1995 • 231 citations

N‐methyl‐D‐aspartate‐activated channels of mouse central neurones in magnesium‐free solutions.

1988 • 230 citations

Distribution of [3H]AMPA binding sites in rat brain as determined by quantitative autoradiography

1984 • 229 citations

Ketamine, an NMDA receptor antagonist, suppresses spatial and temporal properties of burn-induced secondary hyperalgesia in man: a double-blind, cross-over comparison with morphine and placebo

1997 • 227 citations

Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes.

1992 • 226 citations

Heterogeneity of synaptic glutamate receptors on CA3 stratum radiatum interneurones of rat hippocampus.

1993 • 226 citations

The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.

1996 • 225 citations

Functional kainate-selective glutamate receptors in cultured hippocampal neurons.

1993 • 224 citations

Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.

1988 • 223 citations

Protein kinase C modulates glutamate receptor inhibition of Ca2+ channels and synaptic transmission

1993 • 219 citations

Competitive antagonism at metabotropic glutamate receptors by (S) -4-carboxyphenylglycine and (RS) -α-methyl-4-carboxyphenylglycine

1993 • 219 citations

Aniracetam reduces glutamate receptor desensitization and slows the decay of fast excitatory synaptic currents in the hippocampus.

1991 • 213 citations

A glutamate receptor regulates Ca2+ mobilization in hippocampal neurons.

1988 • 210 citations

L-AP4 inhibits calcium currents and synaptic transmission via a G- protein-coupled glutamate receptor

1992 • 210 citations

Cloning and Expression of Rat Metabotropic Glutamate Receptor 8 Reveals a Distinct Pharmacological Profile

1997 • 209 citations

Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies

1996 • 208 citations

Rapid desensitization of glutamate receptors in vertebrate central neurons.

1988 • 205 citations

Impaired Cerebellar Synaptic Plasticity and Motor Performance in Mice Lacking the mGluR4 Subtype of Metabotropic Glutamate Receptor

1996 • 204 citations

The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

1992 • 201 citations

Quisqualate‐ and kainate‐activated channels in mouse central neurones in culture.

1988 • 199 citations

Modulation of N‐methyl‐D‐aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones.

1990 • 199 citations

Reexamination of the effects of MCPG on hippocampal LTP, LTD, and depotentiation

1995 • 197 citations

Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.

1994 • 197 citations

Frequency detection and temporally dispersed synaptic signal association through a metabotropic glutamate receptor pathway

1997 • 197 citations

A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord

1993 • 197 citations

Synaptic localization of kainic acid binding sites

1981 • 195 citations

3,5-Dihydroxyphenylglycine

1992 • 195 citations

cGMP-gated conductance in retinal bipolar cells is suppressed by the photoreceptor transmitter

1991 • 194 citations

Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage

1992 • 193 citations

Motor Discoordination Results from Combined Gene Disruption of the NMDA Receptor NR2A and NR2C Subunits, But Not from Single Disruption of the NR2A or NR2C Subunit

1996 • 189 citations

Agonist analysis of 2‐(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells

1992 • 189 citations

Calcium permeability of the N-methyl-D-aspartate receptor channel in hippocampal neurons in culture.

1993 • 189 citations

The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice

1991 • 188 citations

A benzodiazepine recognition site associated with the non-NMDA glutamate receptor

1993 • 186 citations

Argiotoxin detects molecular differences in AMPA receptor channels

1993 • 186 citations

Quisqualate receptor-mediated depression of calcium currents in hippocampal neurons

1990 • 185 citations

Effect of RNA editing and subunit co‐assembly single‐channel properties of recombinant kainate receptors.

1996 • 184 citations

Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects

1995 • 182 citations

Activation of N‐methyl‐D‐aspartate receptors by L‐glutamate in cells dissociated from adult rat hippocampus.

1992 • 182 citations

AMPA receptors in the rat and primate hippocampus: a possible absence of GLUR2/3 subunits in most interneurons

1996 • 180 citations

Differential modulation by cyclothiazide and concanavalin A of desensitization at native alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid- and kainate-preferring glutamate receptors.

1993 • 177 citations

Functional Correlation of NMDA Receptor ε Subunits Expression with the Properties of Single-Channel and Synaptic Currents in the Developing Cerebellum

1996 • 175 citations

Block of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by polyamines and polyamine toxins.

1996 • 172 citations

Both NMDA and non-NMDA subtypes of glutamate receptors are concentrated at synapses on cerebral cortical neurons in culture

1991 • 172 citations

Spider venom contains specific receptor blocker of glutaminergic synapses

1982 • 169 citations

Activation of a nonselective cationic conductance by metabotropic glutamatergic and muscarinic agonists in CA3 pyramidal neurons of the rat hippocampus

1995 • 168 citations

MCPG Antagonizes Metabotropic Glutamate Receptors but not Long‐term Potentiation in the Hippocampus

1994 • 166 citations

Spider toxins as tools for dissecting elements of excitatory amino acid transmission

1988 • 165 citations

Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons

1997 • 165 citations

Structural determinants of allosteric regulation in alternatively spliced AMPA receptors

1995 • 164 citations

Inhibition of calcium channels in rat CA3 pyramidal neurons by a metabotropic glutamate receptor

1992 • 162 citations

Presynaptic Long-Term Depression at the Hippocampal Mossy Fiber—CA3 Synapse

1996 • 162 citations

Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.

1991 • 161 citations

Roles of specific metabotropic glutamate receptor subtypes in regulation of hippocampal CA1 pyramidal cell excitability

1995 • 159 citations

Patch clamp analysis of excitatory synaptic currents in granule cells of rat hippocampus.

1991 • 159 citations

Induction of an Olfactory Memory by the Activation of a Metabotropic Glutamate Receptor

1994 • 155 citations

Selective distribution of kainate receptor subunit immunoreactivity in monkey neocortex revealed by a monoclonal antibody that recognizes glutamate receptor subunits GluR5/6/7

1993 • 155 citations

Alteration of Ca2+ permeability and sensitivity to Mg2+ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor.

1993 • 155 citations

Glutamate receptors of the kainate type and synaptic transmission

1997 • 152 citations

Dual modulation of synaptic inhibition by distinct metabotropic glutamate receptors in the rat hippocampus.

1995 • 149 citations

Dendritic and somatic glutamate receptor channels in rat cerebellar Purkinje cells

1997 • 148 citations

Activation of Class II or III Metabotropic Glutamate Receptors Protects Cultured Cortical Neurons Against Excitotoxic Degeneration

1995 • 147 citations

Effects of excitatory amino acid antagonists on evoked and spontaneous excitatory potentials in guinea‐pig hippocampus.

1986 • 147 citations

Quantitative localization of AMPA/kainate and kainate glutamate receptor subunit immunoreactivity in neurochemically identified subpopulations of neurons in the prefrontal cortex of the macaque monkey

1993 • 146 citations

Correlation between kinetics and RNA splicing of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in neocortical neurons.

1996 • 145 citations

Reduced spontaneous activity of mice defective in the ε4 subunit of the NMDA receptor channel

1995 • 145 citations

Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI 52466

1989 • 144 citations

Activation and Desensitization of Hippocampal Kainate Receptors

1997 • 144 citations

Kainate receptor subunits expressed in single cultured hippocampal neurons: Molecular and functional variants by RNA editing

1995 • 141 citations

Glutamate metabotropic receptors increase a Ca(2+)-activated nonspecific cationic current in CA1 hippocampal neurons

1994 • 141 citations

Role of the large extracellular domain of metabotropic glutamate receptors in agonist selectivity determination.

1993 • 141 citations

Induction or protection of limbic seizures in mice by mGluR subtype selective agonists

1995 • 140 citations

Modification of NMDA Receptor Channels and Synaptic Transmission by Targeted Disruption of the NR2C Gene

1996 • 139 citations

High‐affinity kainate a domoate receptors in rat brain

1992 • 135 citations

[3H]AMPA binding to glutamate receptor subpopulations in rat brain

1987 • 134 citations

Glutamate mediates a slow synaptic response in hippocampal slice cultures

1991 • 134 citations

Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist

1993 • 134 citations

Effects of a spider toxin on the glutaminergic synapse of lobster muscle.

1983 • 132 citations

The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells

1994 • 132 citations

Distribution of the excitatory amino acid receptor subunits GluR2(4) in monkey hippocampus and colocalization with subunits GluR5-7 and NMDAR1

1995 • 131 citations

Distinct presynaptic metabotropic receptors for l-AP4 and CCG1 on GABAergic terminals: Pharmacological evidence using novel α-methyl derivative mGluR antagonists, MAP4 and MCCG, in the rat thalamus in vivo

1995 • 125 citations

Heterologous expression of metabotropic glutamate receptors in adult rat sympathetic neurons: Subtype-specific coupling to ion channels

1995 • 123 citations

Diazoxide blocks glutamate desensitization and prolongs excitatory postsynaptic currents in rat hippocampal neurons.

1992 • 123 citations

Reduction of resting K+ current by metabotropic glutamate and muscarinic receptors in rat CA3 cells: mediation by G‐proteins.

1994 • 123 citations

6-(1H-Imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione hydrochloride (YM90K) and related compounds: structure-activity relationships for the AMPA-type non-NMDA receptor

1994 • 123 citations

Selective block of recombinant glur6 receptors by NS-102, a novel non-NMDA receptor antagonist

1994 • 123 citations

Dimensions of the narrow portion of a recombinant NMDA receptor channel

1995 • 122 citations

Biochemical and assembly properties of GluR6 and KA2, two members of the kainate receptor family, determined with subunit-specific antibodies.

1994 • 122 citations

Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death

1994 • 122 citations

D-serine antagonized phencyclidine- and MK-801-induced stereotyped behavior and ataxia

1990 • 120 citations

Activation of Metabotropic Glutamate Receptors Prevents Neuronal Apoptosis in Culture

1995 • 119 citations

Single-channel currents from recombinant NM DANRla /NR2D receptors expressed in Xenopus oocytes

1996 • 118 citations

(2S,4R)-4-methylglutamic acid (SYM 2081): a selective, high-affinity ligand for kainate receptors.

1997 • 116 citations

Two types of kainate response in cultured rat hippocampal neurons

1991 • 115 citations

(RS)-alpha-methyl-4-carboxyphenylglycine neither prevents induction of LTP nor antagonizes metabotropic glutamate receptors in CA1 hippocampal neurons

1993 • 114 citations

Differential contribution of the NR1‐ and NR2A‐subunits to the selectivity filter of recombinant NMDA receptor channels.

1996 • 113 citations

Glutamate receptors in cortical plasticity: molecular and cellular biology

1997 • 112 citations

AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity

1995 • 111 citations

Glycine-insensitive desensitization of NMDA responses in cultured mouse embryonic neurons

1990 • 109 citations

Tetanically induced LTP involves a similar increase in the AMPA and NMDA receptor components of the excitatory postsynaptic current: investigations of the involvement of mGlu receptors

1995 • 108 citations

2-Amino-4-phosphonobutyrate selectively blocks mossy fiber-CA3 responses in guinea pig but not rat hippocampus

1984 • 108 citations

Activity‐dependent Regulation of N‐Methyl‐<scp>d</scp>‐aspartate Receptor Subunit Expression in Rat Cerebellar Granule Cells

1994 • 107 citations

Trans-ACPD enhances long-term potentiation in the hippocampus

1991 • 107 citations

Co-activation of metabotropic glutamate and N-methyl-d-aspartate receptors is involved in mechanisms of long-term potentiation maintenance in rat hippocampal ca1 neurons

1993 • 106 citations

Combinations of AMPA Receptor Subunit Expression in Individual Cortical Neurons Correlate with Expression of Specific Calcium-Binding Proteins

1997 • 105 citations

A Novel Allosteric Potentiator of AMPA Receptors: 4-[2-(Phenylsulfonylamino)ethylthio]-2,6-Difluoro-Phenoxyacetamide

1997 • 104 citations

The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injury

1992 • 102 citations

Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices

1996 • 102 citations

Systemic ketamine attenuates nociceptive behaviors in a rat model of peripheral neuropathy

1996 • 102 citations

A Comparison of Two Alternatively Spliced Forms of a Metabotropic Glutamate Receptor Coupled to Phosphoinositide Turnover

1993 • 101 citations

Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal neurones

1995 • 101 citations

Identification of a High Affinity Divalent Cation Binding Site near the Entrance of the NMDA Receptor Channel

1996 • 99 citations

Stereoselective antagonism by enantiomers of alanine and serine of phencyclidine-induced hyperactivity, stereotypy and ataxia in the rat.

1994 • 97 citations

NMDA and Non‐NMDA Receptor Gene Expression Following Global Brain Ischemia in Rats: Effect of NMDA and Non‐NMDA Receptor Antagonists

1994 • 91 citations

Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia

1992 • 90 citations

7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization.

1995 • 90 citations

Voltage‐dependent blockage of Ca(2+)‐permeable AMPA receptors by joro spider toxin in cultured rat hippocampal neurones.

1996 • 89 citations

On the multiple‐conductance single channels activated by excitatory amino acids in large cerebellar neurones of the rat.

1989 • 88 citations

A novel non-NMDA receptor antagonist shows selective displacement of low-affinity [3H]kainate binding

1993 • 88 citations

Distribution of neurones expressing inwardly rectifying and Ca(2+)‐permeable AMPA receptors in rat hippocampal slices.

1996 • 86 citations

Transsynaptic neuronal loss induced in hippocampal slice cultures by a herpes simplex virus vector expressing the GluR6 subunit of the kainate receptor.

1993 • 85 citations

Pertussis toxin inhibits signal transduction at a specific metabolotropic glutamate receptor in primary cultures of cerebellar granule cells

1988 • 85 citations

Mutations in a putative agonist binding region of the AMPA‐selective glutamate receptor channel

1992 • 85 citations

Synchronized oscillations in hippocampal CA3 neurons induced by metabotropic glutamate receptor activation

1995 • 85 citations

Neurotoxicity of NMDA receptor antagonists: an overview.

1994 • 83 citations

Transfection of N‐Methyl‐<scp>d</scp>‐Aspartate Receptors in a Nonneuronal Cell Line Leads to Cell Death

1995 • 82 citations

Activation of glutamate metabotropic receptors induces long-term potentiation

1992 • 78 citations

Novel synaptic potentials in cerebellar Purkenje cells: Probable mediation by metabotropic glutamate receptors

1993 • 77 citations

The Expression of Two Splice Variants of Metabotropic Glutamate Receptor Subtype 5 in the Rat Brain and Neuronal Cells During Development

1995 • 76 citations

Homomeric and heteromeric ion channels formed from the kainate-type subunits GluR6 and KA2 have very small, but different, unitary conductances

1996 • 76 citations

DCG‐IV Selectively Attenuates Rapidly Triggered NMDA‐induced Neurotoxicity in Cortical Neurons

1996 • 75 citations

A Review of NMDA Receptors and the Phencyclidine Model of Schizophrenia

1996 • 75 citations

(2S,3S,4S) α-(Carboxycyclopropyl) glycine is a novel agonist of metabotropic glutamate receptors

1990 • 74 citations

Structural basis for explaining open-channel blockade of the NMDA receptor

1995 • 72 citations

Effects of a spider toxin and its analogue on glutamate-activated currents in the hippocampal CA1 neuron after ischemia

1995 • 72 citations

Activation of Multiple Metabotropic Glutamate Receptor Subtypes Prevents NMDA‐induced Excitotoxicity in Rat Hippocampal Slices

1996 • 71 citations

Metabotropic receptor-mediated long-term potentiation in rat hippocampal slices

1991 • 71 citations

Spermine mediates inward rectification of Ca2+-permeable AMPA receptor channels

1995 • 71 citations

Evidence for more than one type of non‐NMDA receptor in outside‐out patches from cerebellar granule cells of the rat.

1993 • 69 citations

Recombinant Human NMDA Homomeric NR1 Receptors Expressed in Mammalian Cells Form a High‐Affinity Glycine Antagonist Binding Site

1995 • 68 citations

A single amino acid residue determines the Ca2+ permeability of AMPA-selective glutamate receptor channels

1991 • 68 citations

Suppressing action of 2-amino-4-phosphonobutyric acid on mossy fiber-induced excitation in the guinea pig hippocampus

1983 • 68 citations

Cyclothiazide reverses AMPA receptor antagonism of the 2,3-benzodiazepine, GYKI 53655

1993 • 67 citations

The C‐Terminal Domain of the mGluR1 Metabotropic Glutamate Receptor Affects Sensitivity to Agonists

1996 • 67 citations

A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus

1996 • 66 citations

Pharmacological evidence for an involvement of group II and group III mGluRs in the presynaptic regulation of excitatory synaptic responses in the CA1 region of rat hippocampal slices

1995 • 66 citations

Pharmacological properties of acquired excitotoxicity in Chinese hamster ovary cells transfected with N-methyl-D-aspartate receptor subunits.

1996 • 64 citations

Diversity of glutamate receptor subunit mRNA expression within live hippocampal CA1 neurons.

1993 • 62 citations

Amino acid receptors and uptake systems in the mammalian central nervous system.

1988 • 61 citations

Second-order neurones and receptor mechanisms in visual- and olfactory-information processing

1995 • 59 citations

Negative allosteric modulation of wild-type and mutant AMPA receptors by GYKI 53655.

1996 • 58 citations

G protein-coupled receptors mediate a fast excitatory postsynaptic current in CA3 pyramidal neurons in hippocampal slices

1995 • 57 citations

Pharmacological Characterization of Synaptic Transmission through mGluRs in Rat Cerebellar Slices

1997 • 56 citations

On the mechanism of long-term potentiation induced by (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (ACPD) in rat hippocampal slices

1995 • 54 citations

Synaptic expression of the high-affinity kainate receptor subunit KA2 in hippocampal cultures

1995 • 53 citations

Molecular determinants of NMDA receptor function in GABAergic neurones of rat forebrain.

1997 • 52 citations

Organization and quantitative analysis of kainate receptor subunit GluR5-7 immunoreactivity in monkey hippocampus

1993 • 51 citations

Recent basic findings in support of excitatory amino acid hypotheses of schizophrenia

1994 • 50 citations

Pharmacological characterization of MCCG and MAP4 at the mGluR1b, mGluR2 and mGluR4a human metabotropic glutamate receptor subtypes

1995 • 50 citations

Neonatal irradiation prevents the formation of hippocampal mossy fibers and the epileptic action of kainate on rat CA3 pyramidal neurons

1994 • 49 citations

Glutamate Receptor Ion Channel Properties Predict Vulnerability to Cytotoxicity in a Transfected Nonneuronal Cell Line

1996 • 49 citations

Neuroprotective Effect of YM90K, a Novel AMPA/Kainate Receptor Antagonist, in Focal Cerebral Ischemia in Cats

1996 • 48 citations

Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: the use of mutant mice and pharmacological antagonists

1995 • 46 citations

Excitatory amino acids acting on metabotropic glutamate receptors broaden the action potential in hippocampal neurons

1991 • 46 citations

Ion permeation properties of the cloned mouse ϵ2/ζ1 NMDA receptor channel

1994 • 46 citations

Quantitative autoradiographic characterization of the binding of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine ([3H]MK-801) in rat brain: regional effects of polyamines.

1991 • 45 citations

Whole‐cell current noise produced by excitatory and inhibitory amino acids in large cerebellar neurones of the rat.

1989 • 45 citations

Domoic acid induces the release of glutamate in the rat hippocampal CA3 sub-region

1996 • 44 citations

&lt;b&gt;CHEMICAL STRUCTURE OF JORO SPIDER TOXIN &lt;/b&gt;&lt;b&gt;(JSTX) &lt;/b&gt;

1987 • 44 citations

Modulation of epileptiform activity by metabotropic glutamate receptors in immature rat neocortex

1995 • 44 citations

Inwardly Rectifying and Ca²⁺-Permeable AMPA-Type Glutamate Receptor Channels in Rat Neocortical Neurons

1997 • 42 citations

Excitatory synaptic potentials dependent on metabotropic glutamate receptor activation in guinea‐pig hippocampal pyramidal cells.

1995 • 41 citations

Two distinct types of AMPA responses in cultured rat hippocampal neurons

1993 • 41 citations

Modulation of the time course of fast EPSCs and glutamate channel kinetics by aniracetam

1991 • 41 citations

A functionally active presynaptic high-affinity kainate receptor in the rat hippocampal CA3 subregion

1995 • 40 citations

Presynaptic modulation of glutamate and dynorphin release by excitatory amino acids in the guinea-pig hippocampus

1991 • 37 citations

Reduced neuroexcitatory effect of domoic acid following mossy fiber denervation of the rat dorsal hippocampus: further evidence that toxicity of domoic acid involves kainate receptor activation

1989 • 37 citations

Suppression of presynaptic calcium influx by metabotropic glutamate receptor agonists in neonatal rat hippocampus

1995 • 32 citations

Therapeutic Potential of AMPA Receptor Ligands in Neurological Disorders

1996 • 31 citations

Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam

1991 • 29 citations

Cloning and characterization of a bifunctional metabotropic receptor activated by both extracellular calcium and glutamate

1996 • 26 citations

Identification of 2-amino-2-methyl-4-phosphonobutanoic acid as an antagonist at the mGlu4a receptor

1995 • 26 citations

(1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic acid attenuates n-methyl-d-aspartate-induced neuronal cell death in cortical cultures via a reduction in delayed ca2+ accumulation

1993 • 24 citations

Quantal components of the synaptic potential induced in hippocampal neurons by activation of granule cells, and the effect of 2‐amino‐4‐phosphonobutyric acid

1991 • 23 citations

1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices

1995 • 23 citations

Permeation Properties of Na + and Ca 2+ Ions through the Mouse ε 2 /ζ 1 NMDA Receptor Channel Expressed in Xenopus Oocytes

1997 • 22 citations

Adenovirus-mediated expression of AMPA-type glutamate receptor channels in PC12 cells

1997 • 14 citations

Molecular Basis for Functional Differences of AMPA-Subtype Glutamate Receptors

1996 • 7 citations

Single cell RT‐PCR reaches out to the NMDA receptor

1997 • 2 citations