Recent basic findings in support of excitatory amino acid hypotheses of schizophrenia

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia

1991 • 1,819 citations

Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin

1989 • 1,570 citations

Selective activation of the mesocortical DA system by stress

1976 • 1,037 citations

Study of a New Schizophrenomimetic Drug—Sernyl

1959 • 922 citations

Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area

1992 • 832 citations

Effect of Ischemia on the In Vivo Release of Striatal Dopamine, Glutamate, and γ‐Aminobutyric Acid Studied by Intracerebral Microdialysis

1988 • 704 citations

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

1980 • 703 citations

Stress Preferentially Increases Extraneuronal Levels of Excitatory Amino Acids in the Prefrontal Cortex: Comparison to Hippocampus and Basal Ganglia

1993 • 565 citations

Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity

1978 • 550 citations

Dopaminergic Terminals in the Rat Cortex

1973 • 502 citations

Non-competitive antagonists of excitatory amino acid receptors

1987 • 502 citations

Chemical and structural analysis of the relation between cortical inputs and tyrosine hydroxylase-containing terminals in rat neostriatum

1984 • 467 citations

Excitotoxic Amino Acids and Neuropsychiatric Disorders

1990 • 407 citations

Frontal Cortical and Left Temporal Glutamatergic Dysfunction in Schizophrenia

1989 • 392 citations

Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices

1990 • 356 citations

STIMULATORY EFFECT OF <scp>l</scp>‐GLUTAMATE AND RELATED AMINO ACIDS ON [³H]DOPAMINE RELEASE FROM RAT STRIATUM: AN IN VITRO MODEL FOR GLUTAMATE ACTIONS

1979 • 315 citations

In vivo presynaptic control of dopamine release in the cat caudate nucleus—II. Facilitatory or inhibitory influence ofl-glutamate

1986 • 290 citations

Schizophrenia and the frontal lobe

1988 • 264 citations

Mechanisms of action of atypical antipsychotic drugs

1991 • 254 citations

(3H]MK-801 binding sites in postmortem brain regions of schizophrenic patients

1989 • 250 citations

Characterization of L-glutamate action on the release of endogenous dopamine from the rat caudate-putamen.

1989 • 242 citations

Decreased hippocampal expression of a glutamate receptor gene in schizophrenia

1991 • 241 citations

Release-regulating D-2 dopamine receptors are located on striatal glutamatergic nerve terminals.

1988 • 229 citations

Dopaminergic Modulation of Glutamate Release in Striatum as Measured by Microdialysis

1992 • 225 citations

NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus

1990 • 221 citations

Increased [3H]kainic acid binding in the prefrontal cortex in schizophrenia

1983 • 201 citations

Quantitative histological analysis of the cerebellar cortex in the cat

1971 • 199 citations

Presynaptic dopaminergic modulation of cortical input to the striatum

1986 • 184 citations

The glutamate-mediated release of dopamine in the rat striatum: Further characterization of the dual excitatory-inhibitory function

1990 • 179 citations

Effect ofl-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies

1990 • 176 citations

Differential Control by N‐Methyl‐D‐Aspartate and Kainate of Striatal Dopamine Release In Vivo: A Trans‐Striatal Dialysis Study

1988 • 175 citations

Extracellular dopamine in striatum: Influence of nerve impulse activity in medial forebrain bundle and local glutamatergic input

1992 • 123 citations

Typical and atypical neuroleptics antagonize MK-801-induced locomotion and stereotypy in rats

1992 • 122 citations

Distinct presynaptic regulation of dopamine release through NMDA receptors in striosome- and matrix-enriched areas of the rat striatum

1991 • 121 citations

Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats

1993 • 118 citations

Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum

1988 • 113 citations

Distinct actions of endogenous excitatory amino acids on the outflow of dopamine in the nucleus accumbens.

1993 • 110 citations

Novel antipsychotic drugs

1993 • 100 citations

Glutamate: a new target in schizophrenia?

1990 • 98 citations

Haloperidol given chronically decreases basal dopamine in the prefrontal cortex more than the striatum or nucleus accumbens as simultaneously measured by microdialysis

1989 • 74 citations

Glutamate Receptors of a Quisqualate‐Kainate Subtype are Involved in the Presynaptic Regulation of Dopamine Release in the Cat Caudate Nucleus in vivo

1990 • 70 citations

Do endogenous excitatory amino acids influence striatal dopamine release?

1991 • 69 citations

Temporal relationship between neurotransmitter release and ion flux during spreading depression and anoxia

1987 • 66 citations

Excitatory input from sensory motor cortex to neostriatum and its modification by conditioning stimulation of the substantia nigra

1984 • 63 citations

Aspartate-releasing nerve terminals in rat striatum possess D-2 dopamine receptors mediating inhibition of release.

1989 • 59 citations

Depolarization inactivation of dopamine neurons: Terminal release characteristics

1993 • 58 citations

Clozapine attenuates N-methyl-d-aspartate receptor complex-mediated responses in vivo: tentative evidence for a functional modulation by a noradrenergic mechanism

1991 • 57 citations

Convergent prefrontal and nigral projections to the striatum of the rat

1979 • 47 citations

Tonic inhibition of striatal dopamine transmission: effects of benzodiazepine and GABAA receptor antagonists on extracellular dopamine levels

1992 • 38 citations

Biphasic modulation of evoked [³H]D‐aspartate release by D‐2 dopamine receptors in rat striatal slices

1988 • 24 citations

An hypothesis regarding the antipsychotic effect of neuroleptic drugs

1989 • 19 citations

Cited By (0)

Loading...