Identification by mutagenesis of a Mg2+ -block site of the NMDA receptor channel

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1984 • 2,822 citations

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

1986 • 1,842 citations

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Physiological and pathophysiological roles of excitatory amino acids during central nervous system development

1990 • 1,427 citations

Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

NMDA receptors - their role in long-term potentiation

1987 • 1,177 citations

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

1992 • 1,077 citations

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons

1987 • 852 citations

The role of divalent cations in the N‐methyl‐D‐aspartate responses of mouse central neurones in culture.

1988 • 810 citations

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

1992 • 805 citations

Identification of a Site in Glutamate Receptor Subunits That Controls Calcium Permeability

1991 • 774 citations

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.

1988 • 747 citations

Zinc Selectively Blocks the Action of N -Methyl-D-Aspartate on Cortical Neurons

1987 • 678 citations

Frequency-dependent involvement of NMDA receptors in the hippocampus: a novel synaptic mechanism

1986 • 416 citations

Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons

1990 • 302 citations

Cloning, expression and modulation of a mouse NMDA receptor subunit

1992 • 291 citations

Functional expression from cloned cDNAs of glutamate receptor species responsive to kainate and quisqualate

1990 • 178 citations

The inhibition of single N‐methyl‐D‐aspartate‐activated channels by zinc ions on cultured rat neurones.

1990 • 170 citations

Apparent desensitization of NMDA responses in xenopus oocytes involves calcium-dependent chloride current

1990 • 124 citations

A single amino acid residue determines the Ca2+ permeability of AMPA-selective glutamate receptor channels

1991 • 68 citations