Excitotoxity and the NMDA receptor

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

1986 • 1,842 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Brain Lesions, Obesity, and Other Disturbances in Mice Treated with Monosodium Glutamate

1969 • 1,802 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Kainic acid as a tool in neurobiology

1978 • 1,314 citations

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

1976 • 1,247 citations

Quinolinic Acid: An Endogenous Metabolite That Produces Axon-Sparing Lesions in Rat Brain

1983 • 1,247 citations

The Toxic Effect of Sodium L-Glutamate on the Inner Layers of the Retina

1957 • 1,061 citations

Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death

1984 • 893 citations

Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

1976 • 832 citations

Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system

1971 • 808 citations

Hypoglycemia-Induced Neuronal Damage Prevented by an N -Methyl-D-Aspartate Antagonist

1985 • 673 citations

The neurotoxicity of excitatory amino acids is produced by passive chloride influx

1985 • 634 citations

“Epileptic” brain damage in rats induced by sustained electrical stimulation of the perforant path. I. Acute electrophysiological and light microscopic studies

1983 • 554 citations

Huntingtons Disease

1986 • 551 citations

Myocardial ischemia: the pathogenesis of irreversible cell injury in ischemia.

1981 • 441 citations

Excitatory amino acid transmission

1987 • 430 citations

The distribution of hypoglycemic brain damage

1984 • 376 citations

LATHYRISM: EVIDENCE FOR ROLE OF THE NEUROEXCITATORY AMINOACID BOAA

1986 • 373 citations

The role of specific ions in glutamate neurotoxicity

1986 • 298 citations

Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: Dependence on calcium concentration

1986 • 204 citations

Neurological disorders associated with deficiency of glutamate dehydrogenase

1984 • 183 citations

Focal Cortical Seizures Cause Distant Thalamic Lesions

1982 • 172 citations

Perinatal Hypoxia‐Ischemia Disrupts Striatal High‐Affinity [³H]Glutamate Uptake into Synaptosomes

1986 • 160 citations

Ionic requirements for neurotoxic effects of excitatory amino acid analogues in rat cerebellar slices

1986 • 153 citations

The anti-excitotoxic effects of certain anesthetics, analgesics and sedative-hypnotics

1986 • 147 citations

Cysteine-S-Sulfate: Brain Damaging Metabolite in Sulfite Oxidase Deficiency1

1975 • 137 citations

Effects of ischemia-like conditions on cultured neurons: protection by low Na+, low Ca2+ solutions

1986 • 107 citations

Amino acid neurotoxicity: Relationship to neuronal depolarization in rat cerebellar slices

1986 • 90 citations

Reversible and irreversible neuronal damage caused by excitatory amino acid analogues in rat cerebellar slices

1986 • 79 citations

Brain and retinal damage from lathyrus excitotoxin, β-N-oxalyl-L-α,β-diaminopropionic acid

1976 • 77 citations

D-aminaphosphonovalerate is 100-fold more powerful than D-alpha-aminoadipate in blocking N-methylaspartate neurotoxicity

1981 • 61 citations

Synaptic functions in rat sympathetic neurons in microcultures. IV. Nonadrenergic excitation of cardiac myocytes and the variety of multiple-transmitter states

1987 • 42 citations