Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

Physiological and pathophysiological roles of excitatory amino acids during central nervous system development

1990 • 1,427 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

A family of metabotropic glutamate receptors

1992 • 873 citations

A new type of glutamate receptor linked to inositol phospholipid metabolism

1987 • 743 citations

Glutamate stimulates inositol phosphate formation in striatal neurones

1985 • 734 citations

Analysis of combined drug effects: a new look at a very old problem

1983 • 593 citations

Neurotoxicity of excitatory amino acids

1990 • 466 citations

Neurotoxicity ofN-methyl-d-aspartate is markedly enhanced in developing rat central nervous system

1988 • 465 citations

Coupling of Inositol Phospholipid Metabolism with Excitatory Amino Acid Recognition Sites in Rat Hippocampus

1986 • 444 citations

GLUTAMATE-INDUCED NEURONAL NECROSIS IN THE INFANT MOUSE HYPOTHALAMUS

1971 • 409 citations

Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors.

1986 • 399 citations

Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity

1989 • 337 citations

Dantrolene

1986 • 252 citations

Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage

1992 • 193 citations

Astrocyte glutamate receptor activation promotes inositol phospholipid turnover and calcium flux

1986 • 187 citations

Excitatory Amino Acid Agonist‐Antagonist Interactions at 2‐Amino‐4‐Phosphonobutyric Acid‐Sensitive Quisqualate Receptors Coupled to Phosphoinositide Hydrolysis in Slices of Rat Hippocampus

1988 • 181 citations

1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons

1990 • 163 citations

Selective activation of quisqualate metabotropic receptor potentiates NMDA but not AMPA responses

1991 • 135 citations

The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injury

1992 • 102 citations

Quantitative assessment of neuroprotection against NMDA-induced brain injury

1989 • 102 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, And Distinct Properties In The Function Of The Central Nervous System

1989 • 90 citations

Comparison of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD)- and 1R,3S-ACPD-stimulated brain phosphoinositide hydrolysis

1991 • 86 citations

Excitatory amino acid-induced convulsions in neonatal rats mediated by distinct receptor subtypes

1990 • 69 citations

Sequence and expression of a metabotropic glutamate receptor

1992 • 66 citations

In Vitro and In Vivo Pharmacology of trans‐ and cis‐(±)‐1‐Amino‐1,3‐Cyclopentanedicarboxylic Acid: Dissociation of Metabotropic and Ionotropic Excitatory Amino Acid Receptor Effects

1991 • 66 citations

A metabotropic glutamate receptor agonist does not mediate neuronal degeneration in cortical culture

1991 • 42 citations