The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

The organization of behavior

1988 • 8,668 citations

LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS

1957 • 7,145 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

The organization of behavior.

1950 • 6,879 citations

Place navigation impaired in rats with hippocampal lesions

1982 • 6,277 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Simple memory: a theory for archicortex

1971 • 2,722 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

The three-dimensional organization of the hippocampal formation: A review of anatomical data

1989 • 2,107 citations

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system.

1934 • 1,982 citations

Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

1986 • 1,978 citations

Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry

1979 • 1,883 citations

Memory and Brain

1987 • 1,821 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.

1992 • 1,675 citations

Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice

1992 • 1,458 citations

Impaired Spatial Learning in α-Calcium-Calmodulin Kinase II Mutant Mice

1992 • 1,336 citations

A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system

1989 • 1,283 citations

Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain

1996 • 1,272 citations

N-methyl-D-aspartic acid receptor structure and function

1994 • 989 citations

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

1996 • 895 citations

Teratocarcinomas and embryonic stem cells : a practical approach

1987 • 878 citations

Comparison of Two Forms of Long-Term Potentiation in Single Hippocampal Neurons

1990 • 755 citations

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1

1994 • 730 citations

Two components of long-term potentiation induced by different patterns of afferent activation

1990 • 704 citations

Bidirectional synaptic plasticity induced by a single burst during cholinergic theta oscillation in CA1 in vitro

1995 • 634 citations

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice

1994 • 607 citations

Impaired Hippocampal Representation of Space in CA1-Specific NMDAR1 Knockout Mice

1996 • 594 citations

Distinct components of spatial learning revealed by prior training and NMDA receptor blockade

1995 • 560 citations

Analysis of excitatory synaptic action in pyramidal cells using whole‐cell recording from rat hippocampal slices.

1990 • 505 citations

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

1994 • 496 citations

Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice

1994 • 479 citations

Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices

1990 • 396 citations

Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

1993 • 377 citations

Dissociation of the Medial Prefrontal, Posterior Parietal, and Posterior Temporal Cortex for Spatial Navigation and Recognition Memory in the Rat

1994 • 364 citations

MOLECULAR GENETIC ANALYSIS OF SYNAPTIC PLASTICITY, ACTIVITY-DEPENDENT NEURAL DEVELOPMENT, LEARNING, AND MEMORY IN THE MAMMALIAN BRAIN

1997 • 299 citations

A genetic test of the effects of mutations in PKA on mossy fiber ltp and its relation to spatial and contextual learning

1995 • 275 citations

Postnatal ontogenesis of hippocampal CA1 area in rats. I. Development of dendritic arborisation in pyramidal neurons

1981 • 264 citations

Hippocampal synaptic plasticity and NMDA receptors: a role in information storage?

1990 • 259 citations

The development of the hippocampus and dentate gyrus in normal and reeler mice

1979 • 239 citations

Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1

1996 • 230 citations

Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase.

1995 • 212 citations

Establishment of a germ-line competent C57BL/6 embryonic stem cell line

1991 • 204 citations

Strain difference in establishment of mouse embryonic stem (ES) cell lines.

1994 • 197 citations

Production and analysis of chimeric mice

1987 • 175 citations

The perforant path projection to hippocampal area CA1 in the rat hippocampal‐entorhinal cortex combined slice.

1995 • 164 citations

Detailed behavioral analysis of water maze acquisition under APV or CNQX: Contribution of sensorimotor disturbances to drug-induced acquisition deficits.

1996 • 150 citations

Postnatal ontogenesis of hippocampal CA1 area in rats. II. Development of ultrastructure in stratum lacunosum and moleculare

1981 • 125 citations

Detailed behavioral analysis of water maze acquisition under APV or CNQX: Contribution of sensorimotor disturbances to drug-induced acquisition deficits.

1996 • 123 citations

Patch-Pipette Recordings from the Soma, Dendrites, and Axon of Neurons in Brain Slices

1995 • 92 citations

Long‐term Potentiation and Field EPSPs in the Lateral and Medial Perforant Paths in the Dentate Gyrus In Vitro: a Comparison

1992 • 88 citations

Molecular Genetic Analysis

2020 • 77 citations

Intracerebral distribution of DL-2-amino-phosphonopentanoic acid (AP5) and the dissociation of different types of learning

1991 • 41 citations

Preservation of spatial learning in fyn tyrosine kinase knockout mice

1996 • 41 citations

Hippocampal synaptic plasticity and NMDA receptors: a role in information storage?

1991 • 15 citations