Kainic acid as a tool for the study of temporal lobe epilepsy

Kainic acid as a tool in neurobiology

1978 • 1,314 citations

EPILEPSY AND THE TEMPORAL LOBES

1966 • 1,256 citations

Greenfield's neuropathology

1976 • 961 citations

Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells

1978 • 745 citations

Kainic acid: a powerful neurotoxic analogue of glutamate

1974 • 710 citations

Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: A histological study

1980 • 700 citations

Prolonged Epileptic Seizures in Primates

1973 • 531 citations

Kindling

1978 • 482 citations

Cellular and field potential properties of epileptogenic hippocampal slices

1978 • 438 citations

The role of epileptic activity in hippocampal and ‘remote’ cerebral lesions induced by kainic acid

1980 • 428 citations

Lysosomal glycogen storage disease with normal acid maltase

1981 • 391 citations

Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid

1980 • 380 citations

Injections of kainic acid into the amygdaloid complex of the rat: An electrographic, clinical and histological study in relation to the pathology of epilepsy

1980 • 370 citations

Kainate-induced degeneration of neostriatal neurons: dependency upon corticostriatal tract

1978 • 330 citations

Acute dendrotoxic changes in the hippocampus of kainate treated rats

1979 • 306 citations

MESIAL TEMPORAL (AMMON'S HORN) SCLEROSIS AS A COMMON CAUSE OF EPILEPSY

1974 • 294 citations

The kindling model of epilepsy: A review

1980 • 287 citations

Kainic acid neurotoxicity toward hippocampal formation: Dependence on specific excitatory pathways

1980 • 286 citations

The Hippocampal‐Dentate Complex in Temporal Lobe Epilepsy

1974 • 281 citations

Specific binding of [3H]kainic acid to receptor sites in rat brain.

1979 • 280 citations

Actions of several anthelmintics and insecticides on rat cortical neurones

1970 • 266 citations

ACTION OF THE NEUROTOXIN KAINIC ACID ON HIGH AFFINITY UPTAKE OF <scp>l</scp>‐GLUTAMIC ACID IN RAT BRAIN SLICES

1979 • 263 citations

Development of a New Pharmacological Seizure Model: Effects of Anticonvulsants on Cortical‐and Amygdala‐Kindled Seizures in the Rat

1980 • 261 citations

Degeneration of hippocampal CA3 pyramidal cells induced by intraventricular kainic acid

1980 • 257 citations

Evidence suggesting secondary epileptogenic lesions after kainic acid: pretreatment with diazepam reduces distant but not local brain damage

1979 • 249 citations

Die Krampfschädigungen des Gehirns

1951 • 215 citations

Synaptic localization of kainic acid binding sites

1981 • 195 citations

Loss and reacquisition of hippocampal synapses after selective destruction of CA3–CA4 afferents with kainic acid

1980 • 189 citations

Genetic and Related Aetiological Factors in Temporal Lobe Epilepsy

1971 • 183 citations

Structure-activity relations for the neurotoxicity of kainic acid derivatives and glutamate analogues

1978 • 182 citations

Microinjection of kainic acid into the rat hippocampus

1978 • 171 citations

Morphology of the Experimental Epileptic Focus

1964 • 166 citations

A histological study of kainic acid-induced lesions in the rat brain

1978 • 166 citations

Kainic acid: Neurophysiological and neurotoxic actions

1979 • 150 citations

Spontaneously recurrent seizures after intracerebral injections of kainic acid in rat: a possible model of human temporal lobe epilepsy

1980 • 128 citations

Effects of cortical ablation on the neurotoxicity and receptor binding of kainic acid in striatum

1979 • 113 citations

Kainate-like neurotoxicity of folates

1981 • 108 citations

Local and Distant Neuronal Degeneration Following Intrastriatal Injection of Kainic Acid

1980 • 100 citations

Effects of anaesthetics and anticonvulsants on the action of kainic acid in the rat hippocampus

1978 • 94 citations

Methyltetrahydrofolate is a potent and selective agonist for kainic acid receptors

1980 • 93 citations

Epilepsy - Its Phenomena in Man

1973 • 93 citations

Epilepsy: Its Phenomena in Man

1974 • 87 citations

Sustained limbic seizures induced by intraamygdaloid kainic acid in the baboon: Symptomatology and neuropathological consequences

1980 • 83 citations

Cerebral metabolic response to systematic kainic acid: 14-C-deoxyglucose studies

1980 • 80 citations

Morphologische Aspekte der Epilepsien

1963 • 71 citations

Selective destruction by kainic acid of neurons innervated by putative glutamergic afferents in septum and nucleus of the diagonal band

1980 • 65 citations

Regional brain glucose utilization following intrastriatal injections of kainic acid

1980 • 60 citations

Effects of morphine or naloxone on kainic acid neurotoxicity

1979 • 58 citations

The effect of decortication on the excitatory amino acid sensitivity of striatal neurones

1980 • 57 citations

Kainate-induced lesion in the optic tectum: dependency upon optic nerve afferents or glutamate

1980 • 56 citations

Hippocampal lesions indicate differences between the excitotoxic properties of acidic amino acids

1979 • 56 citations

Evidence from lesion studies for epileptogenic and non-epileptogenic neurotoxic interactions between kainic acid and excitatory innervation

1981 • 54 citations

Kainic acid neurotoxicity and seizures

1981 • 52 citations

Cooperative interactions at [3H]kainic acid binding sites in rat and human cerebellum

1979 • 51 citations

Fate of the hippocampal mossy fiber projection after destruction of its postsynaptic targets with intraventricular kainic acid

1981 • 51 citations

A microiontophoretic study of the action of kainic acid and putative neurotransmitters in the rat mesencephalic trigeminal nucleus

1980 • 50 citations

Effects of sustained seizures produced by intrahippocampal injection of kainic acid on noradrenergic neurons: evidence for local control of norepinephrine release.

1980 • 49 citations

Studies of kainate-induced wet-dog shakes in the rat

1978 • 48 citations

Brain Damage and Oral Intake of Certain Amino Acids

1976 • 48 citations

Kainic acid-induced wet dog shakes in rats

1980 • 46 citations

Experimental Psychomotor Epilepsy in the Cat Electro-Clinical and Anatomo-Pathological Correlations

1959 • 42 citations

Localization of receptors for kainic acid on neurons in the innernuclear layer of retina

1979 • 41 citations

ULTRASTRUCTURE OF PENICILLIN-INDUCED EPILEPTOGENIC LESION OF THE CEREBRAL CORTEX IN CATS

1971 • 31 citations

Distribution and persistence of kainic acid in brain

1979 • 29 citations

Systemic dipiperidinoethane mimics the convulsant and neurotoxic actions of kainic acid

1980 • 28 citations

Evidence against an exclusive role of glutamate in kainic acid neurotoxicity

1980 • 27 citations

Can CA3 epileptiform discharge induce bursting in normal CA1 hippocampal neurons?

1980 • 22 citations

Regional distribution of [3H] kainic acid after intraventricular injection

1980 • 20 citations

Protection by 4-amino-hex-5-enoic acid (?-vinyl GABA) and hypobaric hypoxia against kainic acid neurotoxicity

1979 • 20 citations

Focal alteration of dendrites and astrocytes in rat cerebral cortex during initiation of cobalt-induced epileptiform activity

1976 • 13 citations

Evidence for an agonist independent decline of hippocampal muscarinic receptors in kindling

1980 • 11 citations

Enzyme Histochemistry of the Rat Hippocampus During Experimental Status Epilepticus

1978 • 9 citations

Antagonism of intrastriatal and intravenous kainic acid by 1-nuciferine: Comparison with various anticonvulsants and gabamimetics

1980 • 8 citations

Deleted Work

1955 • 0 citations