Cloning of a putative glutamate receptor: A low affinity kainate-binding subunit

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1989 • 3,067 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase.

1986 • 2,118 citations

Excitatory amino acid neurotoxicity and neurodegenerative disease

1990 • 1,781 citations

Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy

1985 • 1,730 citations

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

1991 • 1,465 citations

A Family of AMPA-Selective Glutamate Receptors

1990 • 1,453 citations

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

1976 • 1,247 citations

Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists

1988 • 1,202 citations

Cloning by functional expression of a member of the glutamate receptor family

1989 • 1,009 citations

Molecular Cloning and Functional Expression of Glutamate Receptor Subunit Genes

1990 • 925 citations

Anatomical organization of excitatory amino acid receptors and their pathways

1987 • 877 citations

Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels

1991 • 827 citations

Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors

1984 • 824 citations

Identification of a Site in Glutamate Receptor Subunits That Controls Calcium Permeability

1991 • 774 citations

Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells

1978 • 745 citations

Kainic acid: a powerful neurotoxic analogue of glutamate

1974 • 710 citations

Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: A histological study

1980 • 700 citations

Agonists and antagonists for excitatory amino acid receptors

1987 • 692 citations

Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development

1990 • 646 citations

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

1991 • 638 citations

A family of glutamate receptor genes: Evidence for the formation of heteromultimeric receptors with distinct channel properties

1990 • 581 citations

Glutamate-operated channels: Developmentally early and mature forms arise by alternative splicing

1991 • 560 citations

“Epileptic” brain damage in rats induced by sustained electrical stimulation of the perforant path. I. Acute electrophysiological and light microscopic studies

1983 • 554 citations

Anatomical distributions of four pharmacologically distinct 3H-L-glutamate binding sites

1983 • 522 citations

The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography

1982 • 481 citations

Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells

1991 • 461 citations

Schizophrenia: Some Current Neurochemical Approaches

1983 • 459 citations

Excitatory amino acid receptors in epilepsy

1990 • 428 citations

Excitatory amino acid receptors in the brain: membrane binding and receptor autoradiographic approaches

1990 • 397 citations

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

1993 • 371 citations

Pharmacological and functional diversity of neuronal nicotinic acetylcholine receptors

1991 • 315 citations

New class of glutamate agonist structurally related to ibotenic acid

1980 • 309 citations

BINDING OF [³H]KAINIC ACID, AN ANALOGUE OF <scp>l</scp>‐GLUTAMATE, TO BRAIN MEMBRANES

1976 • 308 citations

Kainic acid neurotoxicity toward hippocampal formation: Dependence on specific excitatory pathways

1980 • 286 citations

Specific binding of [3H]kainic acid to receptor sites in rat brain.

1979 • 280 citations

Subunit promiscuity among hemopoietic growth factor receptors

1991 • 273 citations

Excitatory amino acid receptors in hippocampal neurons: Kainate fails to desensitize them

1986 • 271 citations

Actions of several anthelmintics and insecticides on rat cortical neurones

1970 • 266 citations

Site-directed cross-linking. Establishing the dimeric structure of the aspartate receptor of bacterial chemotaxis.

1988 • 232 citations

β3: A New Member of Nicotinic Acetylcholine Receptor Gene Family Is Expressed in Brain

1989 • 229 citations

Distribution of [3H]AMPA binding sites in rat brain as determined by quantitative autoradiography

1984 • 229 citations

Autoradiographic localization of high-affinity [3H]kainic acid binding sites in the rat forebrain

1983 • 227 citations

Molecular structure of the chick cerebellar kainate-binding subunit of a putative glutamate receptor

1989 • 204 citations

Synaptic localization of kainic acid binding sites

1981 • 195 citations

Regulation of synaptic transmission in the central nervous system: Long-term potentiation

1989 • 186 citations

Sequence and expression of a frog brain complementary DNA encoding a kainate-binding protein

1989 • 181 citations

Functional expression from cloned cDNAs of glutamate receptor species responsive to kainate and quisqualate

1990 • 178 citations

l-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis

1985 • 170 citations

Cellular and synaptic basis of kainic acid-induced hippocampal epileptiform activity

1983 • 157 citations

Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro

1986 • 142 citations

Quantitative autoradiography of binding sites for [3H]AMPA, a structural analogue of glutamic acid

1984 • 135 citations

[3H]AMPA binding to glutamate receptor subpopulations in rat brain

1987 • 134 citations

Thalamic retrograde degeneration following cortical injury: An excitotoxic process?

1990 • 127 citations

Ultrastructural analysis of kainic acid lesion to cerebellar cortex

1980 • 101 citations

A kainic acid receptor from frog brain purified using domoic acid affinity chromatography.

1988 • 88 citations

A voltage-clamp study of isolated stingray horizontal cell non-NMDA excitatory amino acid receptors

1989 • 76 citations

Solubilization of Kainic Acid Binding Sites from Rat Brain

1987 • 71 citations

3H-kainic acid binding: Relevance for evaluating the neurotoxicity of kainic acid

1979 • 51 citations

Autoradiographic localization of specific kainic acid binding sites in pigeon and rat cerebellum

1981 • 50 citations

The Link between Drug Binding and Response: Theories and Observations

1979 • 47 citations

The human neuropathology of encephalopathic mussel toxin poisoning.

1990 • 17 citations