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Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: implications for neuroprotection/neurodegeneration?

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Nitric oxide delays the death of trophic factor-deprived PC12 cells and sympathetic neurons by a cGMP-mediated mechanism

1996 • 171 citations

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Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state

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Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine and S‐nitrosothiols and with changes in glutathione levels

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The nitric oxide hypothesis of aging

1998 • 151 citations

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Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins

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2002 • 141 citations

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2000 • 140 citations

Long-term expression of heme oxygenase-1 (HO-1, HSP-32) following focal cerebral infarctions and traumatic brain injury in humans

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Regulation of heme oxygenase-2 by glucocorticoids in neonatal rat brain: characterization of a functional glucocorticoid response element

1997 • 125 citations

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1998 • 123 citations

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2003 • 108 citations

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2000 • 105 citations

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Heme oxygenase-1 plays an important protective role in experimental autoimmune encephalomyelitis

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2001 • 100 citations

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1997 • 93 citations

Protective Effect of the Xanthate, D609, on Alzheimer's Amyloid β-peptide (1–42)-induced Oxidative Stress in Primary Neuronal Cells

2004 • 93 citations

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Physiological and Toxicological Actions of Nitric Oxide in the Central Nervous System

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Role of the Cytokines in the Hypothalamic-Pituitary-Adrenal and Gonadal Axes

1995 • 85 citations

Spontaneous Expression of Inducible Nitric Oxide Synthase in the Hypothalamus and Other Brain Regions of Aging Rats¹

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Heme: a novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms

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Nitric Oxide Prevents Oxidative Damage Produced bytert-Butyl Hydroperoxide in Erythroleukemia Cells via Nitrosylation of Heme and Non-heme Iron

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An internal enhancer regulates heme- and cadmium-mediated induction of human heme oxygenase-1

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1996 • 69 citations

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Iron Regulates Hyperoxia-Dependent Human Heme Oxygenase 1 Gene Expression in Pulmonary Endothelial Cells

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Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite

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Role for the Ubiquitin-Proteasome System in Parkinson's Disease and Other Neurodegenerative Brain Amyloidoses

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Regional Rat Brain Distribution of Heme Oxygenase-1 and Manganese Superoxide Dismutase mRNA: Relevance of Redox Homeostasis in the Aging Processes

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Nitric oxide synthase inhibition by haem oxygenase decreases macrophage nitric-oxide-dependent cytotoxicity: a negative feedback mechanism for the regulation of nitric oxide production

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Cytokines in Aging and Muscle Homeostasis

1995 • 56 citations

Antioxidant activity of the organotellurium compound 3-[4-(N,N-dimethylamino)benzenetellurenyl]propanesulfonic acid against oxidative stress in synaptosomal membrane systems and neuronal cultures

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Functional Analysis of Heme Regulatory Elements of the Transcriptional Activator Hap1

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1999 • 54 citations

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2002 • 53 citations

Developmentally regulated expression of two transcripts for heme oxygenase-2 with a first exon unique to rat testis: control by corticosterone of the oxygenase protein expression

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Increased cerebrospinal fluid and plasma levels of ultraweak chemiluminescence are associated with changes in the thiol pool and lipid-soluble fluorescence in multiple sclerosis: the pathogenic role of oxidative stress.

1998 • 40 citations

Complex I and the cAMP Cascade in Human Physiopathology

2002 • 39 citations

6‐Hydroxydopamine increases the hydroxylation and nitration of phenylalanine in vivo: implication of peroxynitrite formation

2001 • 38 citations

Non-heme iron protein: A potential target of nitric oxide in acute cardiac allograft rejection

2003 • 37 citations

NMDA receptor activation enhances the release of a cholinergic differentiation peptide (HCNP) from hippocampal neurons in vitro

1998 • 34 citations

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Interaction of Selective Amino Acid Residues of K_Ca Channels with Carbon Monoxide

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Inhibition of Ferritin-Stimulated Microsomal Production of Reactive Oxygen Intermediates by Nitric Oxide

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Oxidative Stress in Animal Models of Accelerated Aging, Alzheimer's Disease and Huntington's Disease

2004 • 4 citations