Back to search

Heme oxygenase-1 plays an important protective role in experimental autoimmune encephalomyelitis

Data up to Jan 2025

Published2001
Citations104
References221

Total Citations Per Year

Abstract

References (221)

Oxygen toxicity, oxygen radicals, transition metals and disease

1984 • 5,301 citations

Bilirubin Is an Antioxidant of Possible Physiological Importance

1987 • 3,406 citations

The ferritins: molecular properties, iron storage function and cellular regulation

1996 • 2,572 citations

THE HEME OXYGENASE SYSTEM:A Regulator of Second Messenger Gases

1997 • 2,481 citations

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

2000 • 2,074 citations

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

1968 • 1,767 citations

Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications

1988 • 1,699 citations

Axonal damage in acute multiple sclerosis lesions

1997 • 1,543 citations

THE NATURAL HISTORY OF MULTIPLE SCLEROSIS: A GEOGRAPHICALLY BASED STUDY

1989 • 1,387 citations

The evolution of free radicals and oxidative stress

2000 • 1,384 citations

Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

1988 • 1,371 citations

The antioxidants of human extracellular fluids

1990 • 1,352 citations

Microsomal Heme Oxygenase

1969 • 1,348 citations

The Molecular Cell Biology of Interferon-gamma and its Receptor

1993 • 1,323 citations

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.

1989 • 1,273 citations

Reduced stress defense in heme oxygenase 1-deficient cells

1997 • 1,263 citations

Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency

1999 • 1,237 citations

Ferritin: a cytoprotective antioxidant strategem of endothelium.

1992 • 1,100 citations

Immunological Aspects of Demyelinating Diseases

1992 • 1,021 citations

Identification of autoantibodies associated with myelin damage in multiple sclerosis

1999 • 881 citations

Heme oxygenase: colors of defense against cellular stress

2000 • 869 citations

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

1993 • 837 citations

Isolation and Characterization of a cDNA from the Rat Brain that Encodes Hemoprotein Heme Oxygenase‐3

1997 • 834 citations

Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress

2000 • 834 citations

Heme oxygenase: A novel target for the modulation of inflammatory response

1996 • 784 citations

Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia

1997 • 775 citations

Oxidative Stress, Antioxidant Defenses, and Damage Removal, Repair, and Replacement Systems

2000 • 762 citations

Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2

1996 • 715 citations

Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury

1999 • 694 citations

Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity

1993 • 688 citations

Matrix metalloproteinases and diseases of the CNS

1998 • 646 citations

OBSERVATIONS ON ATTEMPTS TO PRODUCE ACUTE DISSEMINATED ENCEPHALOMYELITIS IN MONKEYS

1933 • 629 citations

A genetic basis for familial aggregation in multiple sclerosis

1995 • 626 citations

Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination

1975 • 615 citations

Demyelination: The Role of Reactive Oxygen and Nitrogen Species

1999 • 579 citations

TRANSFER OF ALLERGIC ENCEPHALOMYELITIS IN RATS BY MEANS OF LYMPH NODE CELLS

1960 • 540 citations

STRUCTURE-FUNCTION ASPECTS IN THE NITRIC OXIDE SYNTHASES

1997 • 534 citations

Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis

1997 • 534 citations

Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages.

1990 • 511 citations

The epidemiology of multiple sclerosis

2016 • 505 citations

Stress Proteins and Immunology

1990 • 458 citations

Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin.

1991 • 455 citations

Transcriptional control of rat heme oxygenase by heat shock.

1987 • 415 citations

Iron regulates nitric oxide synthase activity by controlling nuclear transcription.

1994 • 413 citations

Experimental allergic encephalomyelitis

1969 • 406 citations

THE RAPID PRODUCTION OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN RHESUS MONKEYS BY INJECTION OF HETEROLOGOUS AND HOMOLOGOUS BRAIN TISSUE WITH ADJUVANTS

1947 • 398 citations

Oxidative stress resulting from ultraviolet A irradiation of human skin fibroblasts leads to a heme oxygenase-dependent increase in ferritin

1993 • 394 citations

Oxidative stress induced in pathologies: The role of antioxidants

1999 • 394 citations

Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice.

1994 • 384 citations

Immunological Aspects of Experimental Allergic Encephalomyelitis and Multiple Sclerosis

1995 • 381 citations

Evidence for genetic basis of multiple sclerosis

1996 • 355 citations

Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide.

1995 • 355 citations

Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: Implications for the treatment of multiple sclerosis

1997 • 337 citations

Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo.

1998 • 327 citations

Mitochondrial oxidative stress after carbon monoxide hypoxia in the rat brain.

1992 • 325 citations

Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar V alpha and V beta chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different.

1989 • 321 citations

Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron.

1991 • 309 citations

Epidemiology of Multiple Sclerosis: A Critical Overview

1993 • 306 citations

Heme oxygenase and oxidative stress. Evidence of involvement of bilirubin as physiological protector against oxidative damage

1994 • 302 citations

Gene regulation of heme oxygenase-1 as a therapeutic target

2000 • 301 citations

SPONTANEOUS ENCEPHALOMYELITIS OF MICE, A NEW VIRUS DISEASE

1937 • 301 citations

Neural roles for heme oxygenase: Contrasts to nitric oxide synthase

2001 • 298 citations

The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement

1991 • 284 citations

Epidemiology of multiple sclerosis in U.S. veterans

1979 • 276 citations

Primary demyelination in Theiler's virus infection. An ultrastructural study.

1975 • 273 citations

The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis

1999 • 270 citations

A beneficial role of bile pigments as an endogenous tissue protector: Anti-complement effects of biliverdin and conjugated bilirubin

1993 • 266 citations

Reversal of long-term potentiation by inhibitors of haem oxygenase

1993 • 265 citations

Viral infections trigger multiple sclerosis relapses: a prospective seroepidemiological study

1993 • 264 citations

Multiple sclerosis in the faroe islands: I. Clinical and epidemiological features

1979 • 257 citations

Expression of heme oxygenase-1 in atherosclerotic lesions.

1998 • 256 citations

Assessment of Animal Models for MS and Demyelinating Disease in the Design of Rational Therapy

1999 • 245 citations

Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat.

1996 • 244 citations

Persistent infection of oligodendrocytes in Theiler's virus-induced encephalomyelitis

1983 • 243 citations

Theiler's Virus-Induced Demyelination: Prevention by Immunosuppression

1976 • 242 citations

Critical Influences of the Cytokine Orchestration on the Outcome of Myelin Antigen‐Specific T‐Cell Autoimmunity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

1995 • 239 citations

Targeted gene deletion of heme oxygenase 2 reveals neural role for carbon monoxide

1997 • 235 citations

Heme oxygenase: Protective gene or Trojan horse

1998 • 234 citations

Nitric oxide and carbon monoxide: parallel roles as neural messengers

1998 • 232 citations

A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry.

1996 • 224 citations

Caeruloplasmin: Physiological and Pathological Perspectives

1981 • 222 citations

Animal models of human disease Experimental autoimmune encephalomyelitis in rodents as a model for human demyelinating disease

1995 • 218 citations

Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse.

1994 • 216 citations

Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury.

1996 • 210 citations

Inhibition of hippocampal heme oxygenase, nitric oxide synthase, and long-term potentiation by metalloporphyrins

1994 • 209 citations

Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV-specific delayed-type hypersensitivity.

1985 • 207 citations

Differential Expression of Inflammatory Cytokines Parallels Progression of Central Nervous System Pathology in Two Clinically Distinct Models of Multiple Sclerosis

1998 • 200 citations

Relapsing experimental allergic encephalomyelitis in the SJL/J mouse.

1981 • 197 citations

Functional Analysis of cDNAs for Two Types of Human Heme Oxygenase and Evidence for Their Separate Regulation1

1993 • 196 citations

Normal and Heat‐Induced Patterns of Expression of Heme Oxygenase‐1 (HSP32) in Rat Brain: Hyperthermia Causes Rapid Induction of mRNA and Protein

1992 • 195 citations

Recognition of the immunodominant myelin basic protein peptide by autoantibodies and HLA-DR2-restricted T cell clones from multiple sclerosis patients. Identity of key contact residues in the B-cell and T-cell epitopes.

1997 • 190 citations

Effect of tumor necrosis factor-α and interleukin-1α on heme oxygenase-1 expression in human endothelial cells

1998 • 186 citations

Human heme oxygenase-2: Characterization and expression of a full-length cDNA and evidence suggesting that the two HO-2 transcripts may differ by choice of polyadenylation signal

1992 • 184 citations

Analysis of the complete nucleotide sequence of the picornavirus Theiler's murine encephalomyelitis virus indicates that it is closely related to cardioviruses

1987 • 181 citations

Simultaneous in situ detection of viral RNA and antigens.

1984 • 179 citations

Monocytes/macrophages isolated from the mouse central nervous system contain infectious Theiler's murine encephalomyelitis virus (TMEV)

1990 • 179 citations

Reactive oxygen species are required for the phagocytosis of myelin by macrophages

1998 • 177 citations

The Increased Susceptibility of Women to Multiple Sclerosis

1992 • 172 citations

Geographic distribution of multiple sclerosis: An update with special reference to Europe and the Mediterranean region

1980 • 172 citations

Expression of immunologically relevant endothelial cell activation antigens on isolated central neurvous system microvessels from patients with multiple sclerosis

1994 • 170 citations

Multiple Sclerosis as a Disease of Immune Regulation

1984 • 169 citations

Genetic models for CNS inflammation

2001 • 168 citations

Heme Oxygenase-2 Is Neuroprotective in Cerebral Ischemia

1999 • 165 citations

T cell receptor β chain usage in myelin basic protein‐specific rat T lymphocytes

1989 • 162 citations

INTERACTIONS BETWEEN OLIGODENDROCYTES AND MICROGLIA

1992 • 161 citations

The heme oxygenase system and its functions in the brain.

2000 • 157 citations

Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides.

1994 • 157 citations

OBSERVATIONS ON ENCEPHALOMYELITIS OF MICE (DA STRAIN)

1952 • 157 citations

Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats

1995 • 156 citations

Sex Hormones in Experimental Autoimmune Encephalomyelitis: Implications for Multiple Sclerosis

2001 • 156 citations

Experimental allergic encephalomyelitis in the rat is inhibited by aminoguanidine, an inhibitor of nitric oxide synthase

1996 • 152 citations

Genetic analysis of susceptibility to Theiler's virus-induced demyelinating disease in mice.

1984 • 148 citations

The toxicity of high-dose superoxide dismutase suggests that superoxide can both initiate and terminate lipid peroxidation in the reperfused heart☆

1994 • 148 citations

EXPERIMENTAL AUTOIMMUNE ENCEPHALO‐MYELITIS IN MICE: GENETIC CONTROL OF SUSCEPTIBILITY*

1976 • 142 citations

Theiler's murine encephalomyelitis: a model of demyelination and persistence of virus.

1987 • 141 citations

Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia

2000 • 140 citations

A Mammalian Iron ATPase Induced by Iron

2000 • 138 citations

Induction of experimental allergic encephalomyelitis in PL/J and (SJL/J x PL/J)F1 mice by myelin basic protein and its peptides: localization of a second encephalitogenic determinant.

1983 • 137 citations

Evidence for increased lipid peroxidation in multiple sclerosis

1992 • 136 citations

Heme Oxygenase-mediated Resistance to Oxygen Toxicity in Hamster Fibroblasts

1997 • 135 citations

Long-term expression of heme oxygenase-1 (HO-1, HSP-32) following focal cerebral infarctions and traumatic brain injury in humans

2000 • 135 citations

Nitric oxide and carbon monoxide as possible retrograde messengers in hgippocampal long‐term potentiation

1994 • 130 citations

Variations in genetic control of susceptibility to Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Differences between susceptible SJL/J and resistant BALB/c strains map near the T cell beta-chain constant gene on chromosome 6.

1987 • 127 citations

Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous system

1997 • 124 citations

Induction of heme oxygenase-1 (HO-1) in glia after traumatic brain injury

1996 • 123 citations

Oxidative injury in the nervous system

1998 • 122 citations

Persistent Theiler's Murine Encephalomyelitis Virus Infection in Mice depends on Plaque Size

1980 • 121 citations

The structure, organization and differential expression of the gene encoding rat heme oxygenase-2

1994 • 117 citations

Ejaculatory abnormalities in mice with targeted disruption of the gene for heme oxygenase-2

1998 • 115 citations

Stress protein-induced immunosuppression: inhibition of cellular immune effector functions following overexpression of haem oxygenase (HSP 32)

1998 • 114 citations

Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats

1995 • 113 citations

The potential role of nitric oxide in multiple sclerosis

1998 • 113 citations

Rapid Production of Acute Disseminated Encephalomyelitis in Rhesus Monkeys by Injection of Brain Tissue With Adjuvants

1946 • 112 citations

Inflammatory Events at the Blood Brain Barrier: Regulation of Adhesion Molecules, Cytokines, and Chemokines by Reactive Nitrogen and Oxygen Species

1997 • 112 citations

Fine specificity of the antibody response to myelin basic protein in the central nervous system in multiple sclerosis: the minimal B-cell epitope and a model of its features.

1995 • 111 citations

Interferon-γ Modulates Human Oligodendrocyte Susceptibility To Fas-Mediated Apoptosis

2000 • 111 citations

Differential regulation of cardiac heme oxygenase‐1 and vascular endothelial growth factor mRNA expressions by hemin, heavy metals, heat shock and anoxia

1996 • 109 citations

Chronic neurologic disease in Theiler's virus infection of SJL/J mice

1976 • 108 citations

Phagocytic properties of microglia in vitro: Implications for a role in multiple sclerosis and EAE

2001 • 105 citations

On the immunopathology of plaque development and repair in multiple sclerosis

1988 • 102 citations

Reperfusion arrhythmias: dose-related protection by anti-free radical interventions

1989 • 102 citations

Susceptibility of inbred mice to chronic central nervous system infection by Theiler's murine encephalomyelitis virus

1979 • 100 citations

Function and induction of the microsomal heme oxygenase

1983 • 98 citations

Studies on demyelination by activated lymphocytes in the rabbit eye. II. Antibody-dependent cell-mediated demyelination.

1977 • 98 citations

Heme Oxygenase A Font of Multiple Messengers

2001 • 98 citations

Heme Oxygenase-1 and Heat Shock Protein 70 Induction in Glia and Neurons throughout Rat Brain after Experimental Intracerebral Hemorrhage

1997 • 97 citations

Free radicals and oxidative stress

2000 • 96 citations

The development of Cop 1 (Copaxone®), and innovative drug for the treatment of multiple sclerosis: personal reflections

1996 • 94 citations

Characterization of two heme oxygenase isoforms in rat spleen: Comparison with the hematin-induced and constitutive isoforms of the liver

1986 • 93 citations

DA strain of Theiler's murine encephalomyelitis virus induces demyelination in nude mice

1984 • 93 citations

Encephalitogenic Epitopes of Myelin Basic Protein

1989 • 89 citations

Genetic Control of Susceptibility to Experimental Allergic Encephalomyelitis and the Ag-B Locus of Rats

1975 • 89 citations

Demyelinating lesions due to Theiler's virus are associated with ongoing central nervous system infection

1986 • 89 citations

Immunohistochemical studies of adult human glial cells

1989 • 89 citations

Induction of Heme Oxygenase Protein Protects Neurons in Cortex and Striatum, But Not in Hippocampus, against Transient Forebrain Ischemia

1998 • 86 citations

Induction of ferritin and heme oxygenase-1 by endotoxin in the lung

1998 • 86 citations

Adoptively transferred chronic relapsing experimental autoimmune encephalomyelitis in the mouse. Neuropathologic analysis.

1984 • 86 citations

Multiple sclerosis. Animal model:Theiler's virus infection in mice.

1977 • 85 citations

The expression of MHC antigens on oligodendrocytes: Induction of polymorphic H-2 expression by lymphokines

1986 • 84 citations

Carbon monoxide as a novel neuroendocrine modulator: inhibition of stimulated corticotropin-releasing hormone release from acute rat hypothalamic explants.

1994 • 83 citations

Myelin proteolipid protein induces demyelinating disease in mice

1987 • 83 citations

The Immunobiology of Multiple Sclerosis: An Autoimmune Disease of the Central Nervous System

1999 • 82 citations

Immunopathology of the lesion in chronic relapsing experimental autoimmune encephalomyelitis in the mouse

1986 • 79 citations

Mechanism of Theiler's virus-induced demyelination in nude mice.

1986 • 76 citations

Renal ischemia/reperfusion up-regulates heme oxygenase-1 (HSP32) expression and increases cGMP in rat heart.

1996 • 73 citations

New Physiological Importance of Two Classic Residual Products: Carbon Monoxide and Bilirubin

1997 • 71 citations

Rat brain microglia and peritoneal macrophages show similar responses to respiratory burst stimulants

1994 • 69 citations

Antibody-induced generation of reactive oxygen radicals by brain macrophages in canine distemper encephalitis: a mechanism for bystander demyelination

1989 • 69 citations

The length of treatment determines whether IFN-beta prevents or aggravates experimental autoimmune encephalomyelitis in Lewis rats.

1996 • 68 citations

ROLE OF BACTERIAL INFECTION IN EXACERBATION OF MULTIPLE SCLEROSIS

1995 • 66 citations

Genetic Factors in Multiple Sclerosis

1993 • 64 citations

On the Respective Roles of Nitric Oxide and Carbon Monoxide in Long-Term Potentiation in the Hippocampus

1998 • 60 citations

Identification of a locus on mouse chromosome 3 involved in differential susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease

1990 • 60 citations

Minireview: Autoimmune responses to myelin proteolipid protein

1994 • 59 citations

The Generation of Nitric Oxide and Carbon Monoxide Produces Opposite Effects on the Release of Immunoreactive Interleukin-1β from the Rat Hypothalamusin Vitro: Evidence for the Involvement of Different Signaling Pathways1

1998 • 58 citations

Induction of heme oxygenase-1 (HO-1) in the contused spinal cord of the rat

1998 • 55 citations

Complex genetic response of human cells to sublethal levels of pure nitric oxide.

1998 • 55 citations

A comparative study of acute and chronic diseases induced by two subgroups of Theiler's murine encephalomyelitis virus

1996 • 54 citations

The cytoprotective effects of bilirubin and biliverdin on rat hepatocytes and human erythrocytes and the impact of albumin

1991 • 54 citations

Kernicterus: an international perspective

2002 • 51 citations

T cell adhesion to endothelial cells and extracellular matrix is modulated upon transendothelial cell migration.

1997 • 50 citations

Characterization of the TO strains of Theiler's mouse encephalomyelitis viruses

1978 • 49 citations

Heme oxygenase induction by UVA radiation. A response to oxidative stress in rat liver

1998 • 48 citations

Influence of sex on susceptibility in the Theiler's murine encephalomyelitis virus model for multiple sclerosis

1990 • 46 citations

Axonal cytoskeleton changes in experimental optic neuritis

1999 • 45 citations

Chamber-specific Regulation of Heme Oxygenase-1 (Heat Shock Protein 32) in Right-sided Congestive Heart Failure

1999 • 45 citations

Polyclonal immunoglobulins (IVIg) modulate nitric oxide production and microglial functions in vitro via Fc receptors

2001 • 45 citations

The neutralization of the mouse-adapted poliomyelitis virus by the sera of children.

1946 • 43 citations

Heat Shock Proteins and Autoimmunity: A Critical Appraisal

1994 • 43 citations

Characterization of rat encephalitogenic T cells bearing non‐Vβ8 T cell recepotors

1992 • 43 citations

Expression of stress proteins heme oxygenase‐1 and ‐2 in acute pancreatitis and pancreatic islet βTC3 and acinar AR42J cells

1997 • 42 citations

Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-alpha) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis

1999 • 41 citations

ACUTE RENAL FAILURE ASSOCIATED WITH LIVER DISEASE IN INDIA: ETIOLOGY AND OUTCOME

2000 • 40 citations

Unconjugated bilirubin inhibits in vitro major histocompatibility complex-unrestricted cytotoxicity of human lymphocytes

1996 • 40 citations

Inhibition of experimental allergic encephalomyelitis in the Lewis rat by paclitaxel

2000 • 40 citations

Carbon monoxide regulates cerebral blood flow in epileptic seizures but not in hypercapnia

1998 • 39 citations

Differences in basal and hyperoxia-associated HO expression in oxidant-resistant hamster fibroblasts

1996 • 39 citations

Serum and cells from Theiler's virus-infected mice fail to injure myelinating cultures or to produce in vivo transfer of disease

1984 • 37 citations

Multiple Transcripts Encoding Heme Oxygenase-2 in Rat Testis: Developmental and Cell-Specific Regulation of Transcripts and Protein1

1995 • 36 citations

Experimental Models of Human Autoimmune Disease: Overview and Prototypes

1992 • 35 citations

Heme oxygenase-1 in lesions of rat experimental autoimmune encephalomyelitis and neuritis

2000 • 34 citations

Susceptibility and resistance to experimental autoimmune encephalomyelitis and neuritis in the guinea pig correlate with the induction of procoagulant and anticoagulant activities.

1984 • 34 citations

Correlation between susceptibility to demyelination and interferon-γ induction of major histocompatibility complex class II antigens on murine cerebrovascular endothelial cells

1993 • 33 citations

Distribution of mitochondrial manganese superoxide dismutase among rat glial cells in culture

1998 • 32 citations

Role of Hydrogen Peroxide in Experimental Optic Neuritis

1993 • 31 citations

Pathogenesis of immune-mediated demyelination in the CNS

1997 • 31 citations

Distribution of mitochondrial manganese superoxide dismutase among rat glial cells in culture

1998 • 28 citations

Structural basis of antimutagenicity of chemicals towards 4-nitroquinoline 1-oxide in Salmonella typhimurium

1994 • 28 citations

Neuroimmunology of multiple sclerosis and experimental allergic encephalomyelitis.

2000 • 26 citations

Experimental allergic encephalomyelitis animal models for analyzing features of multiple sclerosis.

2000 • 25 citations

Anti-inflammatory properties of zinc protoporphyrin disodium (Zn−PP−2Na)

1992 • 24 citations

Immunoregulation of experimental autoimmune encephalomyelitis: editorial overview

1998 • 22 citations

Expression of human HLA-B27 transgene alters susceptibility to murine Theiler's virus-induced demyelination.

1991 • 19 citations

P450 and heme oxygenase enzymes in the basal ganglia and their roles in Parkinson's disease.

1999 • 18 citations

Immunocytochemical localization of heme oxygenase-2 in the rat cerebellum

1996 • 15 citations

Experimental autoimmune encephalomyelitis: isolation and characterization of inflammatory cells from the central nervous system

1989 • 15 citations

Relationship between host age and persistence of Theiler's virus in the central nervous system of mice

1984 • 13 citations

Induction of Experimental Allergic Encephalomyelitis in Suckling Lewis Rats: Role of Age and Type of Sensitizing Neuroantigen

1978 • 12 citations

Differential Susceptibility to Experimental Allergic Encephalomyelitis (EAE) in Genetically Defined A+and A−Rabbits

1990 • 9 citations

Hepatic Heme Oxygenase Is Inducible in Neonatal Rats during the Early Postnatal Period

1996 • 9 citations

Purification of primary antibodies of the myelin basic protein antibody cascade from multiple sclerosis patients. Immunoreactivity studies with homologous and heterologous antigens.

1992 • 6 citations

Cited By (0)

Loading...