Impact of diet on adult hippocampal neurogenesis

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

Mammalian Neural Stem Cells

2000 • 4,689 citations

Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

2003 • 4,175 citations

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

1999 • 3,805 citations

More hippocampal neurons in adult mice living in an enriched environment

1997 • 3,476 citations

A Neurotrophic Model for Stress-Related Mood Disorders

2006 • 3,154 citations

Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus

2000 • 3,047 citations

Mechanisms and Functional Implications of Adult Neurogenesis

2008 • 2,904 citations

Functional neurogenesis in the adult hippocampus

2002 • 2,813 citations

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

2008 • 1,850 citations

Vascular niche for adult hippocampal neurogenesis

2000 • 1,805 citations

Sleep-dependent memory consolidation

2005 • 1,748 citations

Wnt signalling regulates adult hippocampal neurogenesis

2005 • 1,460 citations

Astroglia induce neurogenesis from adult neural stem cells

2002 • 1,422 citations

Brain foods: the effects of nutrients on brain function

2008 • 1,160 citations

Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus

1994 • 986 citations

Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice

2002 • 954 citations

Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice

2002 • 932 citations

Neurogenesis in the Adult Hippocampus

2015 • 904 citations

Neuronal Activity–Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

2009 • 903 citations

A Critical Period for Enhanced Synaptic Plasticity in Newly Generated Neurons of the Adult Brain

2007 • 886 citations

Neuroplasticity in old age: Sustained fivefold induction of hippocampal neurogenesis by long‐term environmental enrichment

2002 • 881 citations

A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning

2002 • 853 citations

Omega 3 Fatty Acids in Bipolar Disorder

1999 • 815 citations

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

2009 • 747 citations

Brain-Derived Neurotrophic Factor and Antidepressant Drugs Have Different But Coordinated Effects on Neuronal Turnover, Proliferation, and Survival in the Adult Dentate Gyrus

2005 • 741 citations

Neurons born in the adult dentate gyrus form functional synapses with target cells

2008 • 709 citations

Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats

2005 • 688 citations

Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells

2004 • 686 citations

Stress and adult neurogenesis

2006 • 685 citations

Diet‐induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle‐aged rats

2008 • 680 citations

Hippocampal Neurogenesis: Regulation by Stress and Antidepressants

2006 • 631 citations

Fluoxetine targets early progenitor cells in the adult brain

2006 • 612 citations

TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment

2008 • 607 citations

Disrupted-In-Schizophrenia 1 Regulates Integration of Newly Generated Neurons in the Adult Brain

2007 • 601 citations

Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways

2006 • 559 citations

Is there a link between adult neurogenesis and learning?

2006 • 529 citations

A role for adult TLX-positive neural stem cells in learning and behaviour

2008 • 512 citations

Experience-Specific Functional Modification of the Dentate Gyrus through Adult Neurogenesis: A Critical Period during an Immature Stage

2007 • 505 citations

The neuroprotective potential of flavonoids: a multiplicity of effects

2008 • 504 citations

Binge ethanol exposure decreases neurogenesis in adult rat hippocampus

2002 • 466 citations

Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice

2002 • 449 citations

Identification of neural stem cells in the adult vertebrate brain

2002 • 414 citations

Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels

2008 • 409 citations

Dietary Restriction Increases the Number of Newly Generated Neural Cells, and Induces BDNF Expression, in the Dentate Gyrus of Rats

2000 • 396 citations

Docosahexaenoic acid promotes neurogenesis in vitro and in vivo

2006 • 392 citations

Computational Influence of Adult Neurogenesis on Memory Encoding

2009 • 364 citations

Fish consumption, n−3 fatty acids, and subsequent 5-y cognitive decline in elderly men: the Zutphen Elderly Study

2007 • 353 citations

Epigenetic Modulation of Seizure-Induced Neurogenesis and Cognitive Decline

2007 • 343 citations

Dietary Restriction Benefits Learning and Motor Performance of Aged Mice

1987 • 341 citations

Curry Consumption and Cognitive Function in the Elderly

2006 • 335 citations

High‐fat diet impairs hippocampal neurogenesis in male rats

2006 • 333 citations

Curcumin Stimulates Proliferation of Embryonic Neural Progenitor Cells and Neurogenesis in the Adult Hippocampus

2008 • 328 citations

Efficacy of ethyl-eicosapentaenoic acid in bipolar depression: Randomised double-blind placebo-controlled study

2005 • 308 citations

The Effect of Flavanol-rich Cocoa on the fMRI Response to a Cognitive Task in Healthy Young People

2006 • 301 citations

Male pheromone–stimulated neurogenesis in the adult female brain: possible role in mating behavior.

2007 • 300 citations

New neurons in the adult brain: The role of sleep and consequences of sleep loss

2008 • 299 citations

Modulation of Hippocampal Plasticity and Cognitive Behavior by Short-term Blueberry Supplementation in Aged Rats

2004 • 299 citations

Neurogenesis in the Dentate Gyrus of the Rat Following Electroconvulsive Shock Seizures

2000 • 298 citations

Omega-3 fatty acids and rodent behavior

2006 • 261 citations

Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice

2003 • 260 citations

Neuroprotective signaling and the aging brain: take away my food and let me run11Published on the World Wide Web on 24 August 2000.

2000 • 241 citations

Neurogenesis in the adult hippocampus

2007 • 237 citations

Effect of zinc supplementation on antidepressant therapy in unipolar depression: a preliminary placebo-controlled study.

2004 • 236 citations

Studies of the effects of high fat diets on cognitive function in a rat model

2005 • 235 citations

Double-Blind, Randomized, Placebo-Controlled Trials of Ethyl-Eicosapentanoate in the Treatment of Bipolar Depression and Rapid Cycling Bipolar Disorder

2006 • 228 citations

Modification of hippocampal neurogenesis and neuroplasticity by social environments

2003 • 226 citations

Effects of n–3 long-chain polyunsaturated fatty acids on depressed mood: systematic review of published trials

2006 • 221 citations

Vitamin A deficiency produces spatial learning and memory impairment in rats

2002 • 221 citations

Neurocognitive deficits in alcoholics and social drinkers: a continuum?

1998 • 208 citations

Comparison of Therapeutic Effects of Omega-3 Fatty Acid Eicosapentaenoic Acid and Fluoxetine, Separately and in Combination, in Major Depressive Disorder

2008 • 208 citations

A model of hippocampal neurogenesis in memory and mood disorders

2006 • 207 citations

13- cis -retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice

2004 • 203 citations

Sex-Dependent Metabolic, Neuroendocrine, and Cognitive Responses to Dietary Energy Restriction and Excess

2007 • 187 citations

Vitamin A deficiency and relational memory deficit in adult mice: relationships with changes in brain retinoid signalling

2003 • 185 citations

Caloric Restriction Increases Learning Consolidation and Facilitates Synaptic Plasticity through Mechanisms Dependent on NR2B Subunits of the NMDA Receptor

2007 • 184 citations

The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes

1989 • 178 citations

Neurogenesis in the Adult Hippocampus

2000 • 173 citations

DHA and cholesterol containing diets influence Alzheimer-like pathology, cognition and cerebral vasculature in APPswe/PS1dE9 mice

2008 • 172 citations

Effect of berberine on proliferation, cell cycle and apoptosis in HeLa and L1210 cells

2003 • 171 citations

Maternal experience inhibits the production of immature neurons in the hippocampus during the postpartum period through elevations in adrenal steroids

2007 • 170 citations

Running is rewarding and antidepressive

2007 • 168 citations

Genetic influence on phenotypic differentiation in adult hippocampal neurogenesis

2002 • 168 citations

Omega-3 fatty acids, energy substrates, and brain function during aging

2006 • 166 citations

Chronic alcohol exposure reduces hippocampal neurogenesis and dendritic growth of newborn neurons

2005 • 163 citations

Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms

2008 • 160 citations

Fibroblast Growth Factor Receptor-1 is Required for Long-Term Potentiation, Memory Consolidation, and Neurogenesis

2007 • 156 citations

The FGF-2/FGFRs neurotrophic system promotes neurogenesis in the adult brain

2009 • 150 citations

Inflammation Regulates Functional Integration of Neurons Born in Adult Brain

2008 • 144 citations

Antidepressant activity of zinc and magnesium in view of the current hypotheses of antidepressant action.

2008 • 144 citations

Adult hippocampal neurogenesis and aging

2007 • 139 citations

Abstinence following Alcohol Drinking Produces Depression-Like Behavior and Reduced Hippocampal Neurogenesis in Mice

2008 • 138 citations

Neurogenin2 Directs Granule Neuroblast Production and Amplification while NeuroD1 Specifies Neuronal Fate during Hippocampal Neurogenesis

2009 • 138 citations

Omega-3 fatty acids and major depression: a primer for the mental health professional.

2004 • 135 citations

Influences of reduced masticatory sensory input from soft-diet feeding upon spatial memory/learning ability in mice

2007 • 135 citations

Zinc deficiency induces depression-like symptoms in adult rats

2008 • 130 citations

HIV/gp120 Decreases Adult Neural Progenitor Cell Proliferation via Checkpoint Kinase-Mediated Cell-Cycle Withdrawal and G1 Arrest

2007 • 126 citations

Cdk5 Regulates Accurate Maturation of Newborn Granule Cells in the Adult Hippocampus

2008 • 121 citations

Cocoa Flavanols and Brain Perfusion

2006 • 119 citations

Retinoic Acid Restores Adult Hippocampal Neurogenesis and Reverses Spatial Memory Deficit in Vitamin A Deprived Rats

2008 • 114 citations

Omega-3 Eicosapentaenoic Acid in Bipolar Depression

2005 • 110 citations

Neurogenesis and depression: what animal models tell us about the link

2007 • 104 citations

Caffeine improves adult mice performance in the object recognition task and increases BDNF and TrkB independent on phospho-CREB immunocontent in the hippocampus

2008 • 104 citations

Folate Deficiency Induces Neurodegeneration and Brain Dysfunction in Mice Lacking Uracil DNA Glycosylase

2008 • 102 citations

Recent advances in berry supplementation and age-related cognitive decline

2008 • 101 citations

Caffeine, cognitive failures and health in a non‐working community sample

2008 • 100 citations

Folate deficiency inhibits proliferation of adult hippocampal progenitors

2005 • 96 citations

Glucose and age-related changes in memory

2005 • 93 citations

Effect of Dietary n-3 Polyunsaturated Fatty Acids on Brain Lipid Fatty Acid Composition, Learning Ability, and Memory of Senescence-Accelerated Mouse

2008 • 91 citations

Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage

2007 • 89 citations

Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system

2008 • 88 citations

Dietary flavonoid (−)epicatechin stimulates phosphatidylinositol 3‐kinase‐dependent anti‐oxidant response element activity and up‐regulates glutathione in cortical astrocytes

2008 • 86 citations

Hippocampus‐dependent learning is associated with adult neurogenesis in MRL/MpJ mice

2009 • 78 citations

Changes in adult neurogenesis in neurodegenerative diseases: cause or consequence?

2008 • 73 citations

Nutritional modulation of ageing: Genomic and epigenetic approaches

2006 • 69 citations

Inhibitory effects of caffeine on hippocampal neurogenesis and function

2007 • 68 citations

The total flavonoids extracted from Xiaobuxin-Tang up-regulate the decreased hippocampal neurogenesis and neurotrophic molecules expression in chronically stressed rats

2008 • 66 citations

Cell Proliferation in the Dentate Gyrus of Rat Hippocampus Is Inhibited by Soft Diet Feeding

2005 • 63 citations

Changes in neurogenesis in dementia and Alzheimer mouse models: are they functionally relevant?

2007 • 62 citations

Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2‐dependent cyclin E expression

2008 • 62 citations

Caffeine alters proliferation of neuronal precursors in the adult hippocampus

2009 • 56 citations

Soft-diet feeding decreases dopamine release and impairs aversion learning in Alzheimer model rats

2008 • 53 citations

Antidepressant-like effects of a cocoa polyphenolic extract in Wistar–Unilever rats

2008 • 53 citations

Rat electropharmacograms of the flavonoids rutin and quercetin in comparison to those of moclobemide and clinically used reference drugs suggest antidepressive and/or neuroprotective action

2009 • 48 citations

Effects of moderate chronic ethanol consumption on hippocampal nicotinic receptors and associative learning

2008 • 34 citations

Induction of Neurogenesis in the Adult Dentate Gyrus by Cortical Spreading Depression

2008 • 33 citations

Dietary restriction increases hippocampal neurogenesis by molecular mechanisms independent of NMDA receptors

2005 • 27 citations

Chronic 13-cis-retinoic acid administration disrupts network interactions between the raphe nuclei and the hippocampal system in young adult mice

2009 • 26 citations