Rat electropharmacograms of the flavonoids rutin and quercetin in comparison to those of moclobemide and clinically used reference drugs suggest antidepressive and/or neuroprotective action

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The small intestine can both absorb and glucuronidate luminal flavonoids

1999 • 408 citations

Plants and the central nervous system

2003 • 352 citations

Acetylcholinesterase Inhibition by Flavonoids from Agrimonia pilosa

2007 • 257 citations

Neuroprotective Effects of Quercetin and Rutin on Spatial Memory Impairment in an 8-Arm Radial Maze Task and Neuronal Death Induced by Repeated Cerebral Ischemia in Rats

2007 • 252 citations

Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson Diseases

2008 • 214 citations

Myricetin and quercetin, the flavonoid constituents ofGinkgo biloba extract, greatly reduce oxidative metabolism in both resting and Ca2+-loaded brain neurons

1994 • 213 citations

Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: Evidence for the involvement of the serotonergic and noradrenergic systems

2008 • 199 citations

Neuroprotective effect of antioxidants on ischaemia and reperfusion-induced cerebral injury

2003 • 164 citations

Cell culture protection andin vivo neuroprotective capacity of flavonoids

2003 • 163 citations

Quercetin from Shallots (Allium cepa L. var.aggregatum) Is More Bioavailable Than Its Glucosides , ,3

2008 • 162 citations

Rutin is Essential for the Antidepressant Activity of Hypericum perforatum Extracts in the Forced Swimming Test

2002 • 150 citations

Monoamine oxidase inhibitory components fromCayratia japonica

2007 • 125 citations

Quercetin as the Active Principle ofHypericumhircinumExerts a Selective Inhibitory Activity against MAO-A: Extraction, Biological Analysis, and Computational Study

2006 • 114 citations

Determination of St. John's wort flavonoid-metabolites in rat brain through high performance liquid chromatography coupled with fluorescence detection

2006 • 85 citations

Involvement of type A monoamine oxidase in neurodegeneration: regulation of mitochondrial signaling leading to cell death or neuroprotection

2006 • 85 citations

Antidepressant-Like Effect of Onion (Allium cepaL.) Powder in a Rat Behavioral Model of Depression

2008 • 80 citations

Monoamine Oxidase B and Free Radical Scavenging Activities of Natural Flavonoids inMelastoma candidumD. Don

2001 • 79 citations

Pharmacological modulation of cholinergic brain activity and its reflection in special EEG frequency ranges from various brain areas in the freely moving rat (Tele-Stereo-EEG)

2005 • 72 citations

Different effects of the constituents of EGb761 on apoptosis in rat cerebellar granule cells induced by hydroxyl radicals

1999 • 66 citations

Absorption of Quercetin and Rutin in Rat Small Intestine

2005 • 62 citations

Protective effect of rutin, a polyphenolic flavonoid against haloperidol‐induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes

2007 • 62 citations

Different anticonvulsive effects of hesperidin and its aglycone hesperetin on electrical activity in the rat hippocampus in-vitro

2006 • 61 citations

Pharmacological Modulation of Dopaminergic Brain Activity and Its Reflection in Spectral Frequencies of the Rat Electropharmacogram

2008 • 60 citations

Quercetin Potentiates <i>L</i>-Dopa Reversal of Drug-Induced Catalepsy in Rats: Possible COMT/MAO Inhibition

2003 • 51 citations

Neuroprotective Effects of Natural Products: Interaction with Intracellular Kinases, Amyloid Peptides and a Possible Role for Transthyretin

2007 • 49 citations

Preclinical data base of pharmaco-specific rat EEG fingerprints (tele-stereo-EEG).

2003 • 48 citations

Investigation of Pharmacokinetic Data of Hypericin, Pseudohypericin, Hyperforin and the Flavonoids Quercetin and Isorhamnetin Revealed from Single and Multiple Oral Dose Studies with a Hypericum Extract Containing Tablet in Healthy Male Volunteers

2011 • 47 citations

St. John's wort flavonoids and their metabolites show antidepressant activity and accumulate in brain after multiple oral doses.

2008 • 46 citations

Moclobemide: Evolution, Pharmacodynamic, and Pharmacokinetic Properties

2002 • 45 citations

Radioelectroencephalographic Comparison of Memantine with Receptor-Specific Drugs Acting on Dopaminergic Transmission in Freely Moving Rats

1987 • 38 citations

The Inhibition of Monoamine Oxidase Activity by Various Antidepressants. Differences Found in Various Mammalian Species.

1999 • 28 citations

Theogallin and <scp>l</scp>-theanine as active ingredients in decaffeinated green tea extract: II. Characterization in the freely moving rat by means of quantitative field potential analysis

2007 • 19 citations