The total flavonoids extracted from Xiaobuxin-Tang up-regulate the decreased hippocampal neurogenesis and neurotrophic molecules expression in chronically stressed rats

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

2003 • 4,175 citations

A Neurotrophic Model for Stress-Related Mood Disorders

2006 • 3,154 citations

Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus

2000 • 3,047 citations

Function and Regulation of CREB Family Transcription Factors in the Nervous System

2002 • 2,037 citations

Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation

1997 • 1,773 citations

Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms

2007 • 1,669 citations

Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

2001 • 1,554 citations

Chronic Mild Stress (CMS) Revisited: Consistency and Behavioural-Neurobiological Concordance in the Effects of CMS

2005 • 1,515 citations

Neurogenesis in the Neocortex of Adult Primates

1999 • 1,268 citations

Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat

1993 • 1,215 citations

Infusion of Brain-Derived Neurotrophic Factor into the Lateral Ventricle of the Adult Rat Leads to New Neurons in the Parenchyma of the Striatum, Septum, Thalamus, and Hypothalamus

2001 • 925 citations

Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment

2006 • 770 citations

The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death

2000 • 690 citations

Role of neurotrophic factors in depression

2006 • 655 citations

Hippocampal Neurogenesis: Regulation by Stress and Antidepressants

2006 • 631 citations

Rapid extension of axons into the CA3 region by adult-generated granule cells

1999 • 597 citations

Regulation of transcription factors by neuronal activity

2002 • 584 citations

Regulation of Neurogenesis in Adult Mouse Hippocampus by cAMP and the cAMP Response Element-Binding Protein

2002 • 478 citations

Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects

2005 • 344 citations

Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect

2001 • 312 citations

Blockade of CRF1 or V1b receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression

2003 • 309 citations

Signaling Pathways Regulating Gene Expression, Neuroplasticity, and Neurotrophic Mechanisms in the Action of Antidepressants: A Critical Overview

2006 • 302 citations

Effects of chronic mild stress on sexual behavior, locomotor activity and consumption of sucrose and saccharine solutions

2005 • 285 citations

Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats

2007 • 272 citations

Localization of Phosphorylated cAMP Response Element-Binding Protein in Immature Neurons of Adult Hippocampus

2002 • 269 citations

BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone

1992 • 241 citations

Serotonin may stimulate granule cell proliferation in the adult hippocampus, as observed in rats grafted with foetal raphe neurons

2000 • 238 citations

Evaluation of Cell Proliferation in Rat Tissues with BrdU, PCNA, Ki-67(MIB-5) Immunohistochemistry and In Situ Hybridization for Histone mRNA

2003 • 238 citations

Neurogenesis in the adult hippocampus

2007 • 237 citations

Current St. John's wort research from mode of action to clinical efficacy

2003 • 228 citations

Depression – emerging insights from neurobiology

2001 • 205 citations

Activation of cAMP Signaling Facilitates the Morphological Maturation of Newborn Neurons in Adult Hippocampus

2004 • 190 citations

Neurogenesis and depression: etiology or epiphenomenon?

2004 • 182 citations

Regulation of Hippocampal Gene Expression Is Conserved in Two Species Subjected to Different Stressors and Antidepressant Treatments

2005 • 176 citations

Cyclic AMP response element binding protein and brain-derived neurotrophic factor: Molecules that modulate our mood?

2006 • 134 citations

Behavioral, neurochemical and neuroendocrine effects of the ethanolic extract from Curcuma longa L. in the mouse forced swimming test

2006 • 125 citations

Synapse loss from chronically elevated glucocorticoids: Relationship to neuropil volume and cell number in hippocampal area CA3

2006 • 121 citations

Antidepressant effects of Banxia Houpu decoction, a traditional Chinese medicinal empirical formula

2000 • 117 citations

Neurogenesis and depression: what animal models tell us about the link

2007 • 104 citations

Behavioral and biochemical studies on chronic mild stress models in rats treated with a Chinese traditional prescription Banxia-houpu decoction

2003 • 96 citations

Hippocampal Neurogenesis, Depressive Disorders, and Antidepressant Therapy

2007 • 91 citations

Antidepressant effect of Chaihu-Shugan-San extract and its constituents in rat models of depression

2004 • 81 citations

Role for serotonin in the antidepressant-like effect of a flavonoid extract of Xiaobuxin-Tang

2008 • 62 citations

Agmatine increases proliferation of cultured hippocampal progenitor cells and hippocampal neurogenesis in chronically stressed mice

2006 • 44 citations

Regulation of adult hippocampal neurogenesis: relevance to depression

2007 • 44 citations

Antidepressant effect of three traditional Chinese medicines in the learned helplessness model

2004 • 42 citations

Granule neurons generated during development extend divergent axon collaterals to hippocampal area CA3

2002 • 40 citations

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2007 • 21 citations

Japonicins A and B from the flowers of Inula japonica

2006 • 18 citations

FLAVONOIDAL COMPOUNDS OFINULA VISCOSAPART II

1977 • 12 citations

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2008 • 3 citations