New neurons in the adult brain: The role of sleep and consequences of sleep loss

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

2013 • 8,227 citations

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

Functional neurogenesis in the adult hippocampus

2002 • 2,813 citations

Causal Relationship Between Stressful Life Events and the Onset of Major Depression

1999 • 2,365 citations

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

2003 • 2,295 citations

THE EFFECTS OF STRESSFUL LIFE EVENTS ON DEPRESSION

1997 • 2,031 citations

ADULT NEUROGENESIS IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM

2005 • 1,794 citations

Sleep-dependent memory consolidation

2005 • 1,748 citations

Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

2001 • 1,554 citations

Human emotion and memory: interactions of the amygdala and hippocampal complex

2004 • 1,438 citations

Regional dissociations within the hippocampus—memory and anxiety

2004 • 1,394 citations

Milestones of neuronal development in the adult hippocampus

2004 • 1,389 citations

Adult neurogenesis and functional plasticity in neuronal circuits

2006 • 1,324 citations

Functional differentiation in the hippocampus

1998 • 1,301 citations

Adult hippocampal neurogenesis in depression

2007 • 1,170 citations

Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus

1994 • 986 citations

Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus

2001 • 976 citations

Adult Neurogenesis: From Precursors to Network and Physiology

2005 • 961 citations

Adult brain neurogenesis and psychiatry: a novel theory of depression

2000 • 936 citations

Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice

2002 • 932 citations

Peripheral Infusion of IGF-I Selectively Induces Neurogenesis in the Adult Rat Hippocampus

2000 • 838 citations

Restricted and disrupted sleep: Effects on autonomic function, neuroendocrine stress systems and stress responsivity

2008 • 808 citations

Hippocampal neurogenesis in adult Old World primates

1999 • 804 citations

Stress and hippocampal neurogenesis

1999 • 799 citations

Neurogenesis in the adult brain: death of a dogma

2000 • 796 citations

Sleep Deprivation and Activation of Morning Levels of Cellular and Genomic Markers of Inflammation

2006 • 765 citations

Are Spatial Memories Strengthened in the Human Hippocampus during Slow Wave Sleep?

2004 • 753 citations

Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats

2005 • 688 citations

Efficacy of doublecortin as a marker to analyse the absolute number anddendritic growth of newly generated neurons in the adult dentate gyrus

2004 • 638 citations

How widespread is adult neurogenesis in mammals?

2007 • 634 citations

Potential role for adult neurogenesis in the encoding of time in new memories

2006 • 631 citations

Functional significance of adult neurogenesis

2004 • 625 citations

BrdU immunohistochemistry for studying adult neurogenesis: Paradigms, pitfalls, limitations, and validation

2006 • 614 citations

Primary insomnia: a risk factor to develop depression?

2002 • 609 citations

Adult-generated neurons in the dentate gyrus send axonal projections to field CA3 and are surrounded by synaptic vesicles

1999 • 561 citations

Synapse formation on neurons born in the adult hippocampus

2007 • 550 citations

Elevated Inflammatory Markers in Response to Prolonged Sleep Restriction Are Associated With Increased Pain Experience in Healthy Volunteers

2007 • 549 citations

Is there a link between adult neurogenesis and learning?

2006 • 529 citations

Serotonin-Induced Increases in Adult Cell Proliferation and Neurogenesis are Mediated Through Different and Common 5-HT Receptor Subtypes in the Dentate Gyrus and the Subventricular Zone

2003 • 506 citations

Neurogenesis in adult primate neocortex: an evaluation of the evidence

2002 • 480 citations

Sleep Deprivation Selectively Impairs Memory Consolidation for Contextual Fear Conditioning

2003 • 448 citations

Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain

2007 • 430 citations

The generation, migration, and differentiation of olfactory neurons in the adult primate brain

2001 • 416 citations

What causes the hippocampal volume decrease in depression?

2007 • 401 citations

Memory consolidation and reconsolidation: what is the role of sleep?

2005 • 395 citations

Spatial Learning Depends on Both the Addition and Removal of New Hippocampal Neurons

2007 • 394 citations

Sleep Deprivation Causes Behavioral, Synaptic, and Membrane Excitability Alterations in Hippocampal Neurons

2003 • 393 citations

The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for?

2008 • 368 citations

Chronic stress: Implications for neuronal morphology, function and neurogenesis

2007 • 367 citations

Serotonin and the sleep/wake cycle: special emphasis on microdialysis studies

2000 • 313 citations

Electrophysiological Differentiation of New Neurons in the Olfactory Bulb

2003 • 300 citations

Impaired Declarative Memory Consolidation During Sleep in Patients With Primary Insomnia: Influence of Sleep Architecture and Nocturnal Cortisol Release

2006 • 250 citations

Differential effects of learning on neurogenesis: learning increases or decreases the number of newly born cells depending on their birth date

2003 • 241 citations

Chronic Insomnia and MRI-Measured Hippocampal Volumes: A Pilot Study

2007 • 240 citations

Young and excitable: the function of new neurons in the adult mammalian brain

2005 • 236 citations

Adult hippocampal neurogenesis and voluntary running activity: Circadian and dose‐dependent effects

2004 • 231 citations

5-HT1A receptor antagonist administration decreases cell proliferation in the dentate gyrus

2002 • 229 citations

Sleep deprivation inhibits adult neurogenesis in the hippocampus by elevating glucocorticoids

2006 • 226 citations

Sleep and memory: a molecular perspective

2001 • 218 citations

Recovery Sleep Following Sleep Deprivation in Intact and Suprachiasmatic Nuclei-Lesioned Rats

1983 • 218 citations

Sleep Restriction Suppresses Neurogenesis Induced by Hippocampus-Dependent Learning

2005 • 214 citations

Reductions in circulating anabolic hormones induced by sustained sleep deprivation in rats

2004 • 208 citations

Molecular regulation of adult CNS neurogenesis: an integrated view

2005 • 207 citations

Sleep Deprivation Reduces Proliferation of Cells in the Dentate Gyrus of the Hippocampus in Rats

2003 • 191 citations

Suppression of hippocampal plasticity‐related gene expression by sleep deprivation in rats

2006 • 189 citations

Chronically Restricted Sleep Leads to Depression-Like Changes in Neurotransmitter Receptor Sensitivity and Neuroendocrine Stress Reactivity in Rats

2008 • 187 citations

Sleep deprivation suppresses neurogenesis in the adult hippocampus of rats

2005 • 184 citations

Increased nocturnal interleukin-6 excretion in patients with primary insomnia: A pilot study

2005 • 181 citations

Sleep after spatial learning promotes covert reorganization of brain activity

2006 • 167 citations

Toward an Integrative Perspective on Hippocampal Function: From the Rapid Encoding of Experience to Adaptive Behavior

2007 • 146 citations

Magnetic resonance imaging of the migration of neuronal precursors generated in the adult rodent brain

2006 • 137 citations

Hippocampal neurogenesis is reduced by sleep fragmentation in the adult rat

2007 • 127 citations

Too Little Sleep Gradually Desensitizes the Serotonin 1A Receptor System

2005 • 123 citations

Sleep deprivation can inhibit adult hippocampal neurogenesis independent of adrenal stress hormones

2008 • 118 citations

The Suprachiasmatic Nucleus Regulates Sleep Timing and Amount in Mice

2004 • 116 citations

Impaired Sleep-Related Memory Consolidation in Primary Insomnia—A Pilot Study

2006 • 114 citations

Rapid Eye Movement Sleep Deprivation Contributes to Reduction of Neurogenesis in the Hippocampal Dentate Gyrus of the Adult Rat

2008 • 112 citations

Sleep deprivation impairs hippocampus‐mediated contextual learning but not amygdala‐mediated cued learning in rats

2004 • 106 citations

Hippocampal cell proliferation across the day: Increase by running wheel activity, but no effect of sleep and wakefulness

2005 • 99 citations

Sleep restriction by forced activity reduces hippocampal cell proliferation

2005 • 88 citations

Effects of sleep deprivation and recovery sleep upon cell proliferation in adult rat dentate gyrus

2005 • 83 citations

Persistently High Corticosterone Levels but Not Normal Circadian Fluctuations of the Hormone Affect Cell Proliferation in the Adult Rat Dentate Gyrus

2002 • 59 citations

Circadian variation in mouse hippocampal cell proliferation

2006 • 43 citations

Cell proliferation in the dentate gyrus of the adult rat fluctuates with the light–dark cycle

2007 • 38 citations