Curcumin Stimulates Proliferation of Embryonic Neural Progenitor Cells and Neurogenesis in the Adult Hippocampus

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

1999 • 3,805 citations

More hippocampal neurons in adult mice living in an enriched environment

1997 • 3,476 citations

Running enhances neurogenesis, learning, and long-term potentiation in mice

1999 • 2,829 citations

Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

2004 • 2,165 citations

Curcumin as “Curecumin”: From kitchen to clinic

2007 • 2,121 citations

Neurogenesis in the adult is involved in the formation of trace memories

2001 • 2,014 citations

Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus

1997 • 1,880 citations

The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse

2001 • 1,482 citations

Anti-tumour and antioxidant activity of natural curcuminoids

1995 • 1,068 citations

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

2003 • 989 citations

A unified hypothesis on the lineage of neural stem cells

2001 • 976 citations

Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice

2002 • 932 citations

Multipotent neural cell lines can engraft and participate in development of mouse cerebellum

1992 • 928 citations

Chemopreventive and therapeutic effects of curcumin

2004 • 850 citations

Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory

1999 • 840 citations

Restoring production of hippocampal neurons in old age

1999 • 717 citations

Curcumin: Getting Back to the Roots

2005 • 692 citations

How widespread is adult neurogenesis in mammals?

2007 • 634 citations

The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior

2007 • 628 citations

Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis.

1991 • 571 citations

Evidence That Curcumin Suppresses the Growth of Malignant Gliomas in Vitro and in Vivo through Induction of Autophagy: Role of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways

2007 • 511 citations

Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology

2001 • 508 citations

Disruption of neurogenesis by amyloid β‐peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease

2002 • 460 citations

Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice

2002 • 449 citations

Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease

2005 • 433 citations

Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats

2003 • 404 citations

Dietary Restriction Increases the Number of Newly Generated Neural Cells, and Induces BDNF Expression, in the Dentate Gyrus of Rats

2000 • 396 citations

Neurohormetic phytochemicals: low-dose toxins that induce adaptive neuronal stress responses

2006 • 338 citations

Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition

2006 • 280 citations

Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats

2007 • 272 citations

Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis

2000 • 253 citations

Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver

1998 • 246 citations

MOLECULAR TARGETS OF CURCUMIN

2007 • 211 citations

An Essential Role for a MEK-C/EBP Pathway during Growth Factor-Regulated Cortical Neurogenesis

2002 • 201 citations

PDGF and FGF-2 Signaling in Oligodendrocyte Progenitor Cells: Regulation of Proliferation and Differentiation by Multiple Intracellular Signaling Pathways

2000 • 195 citations

Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition

2007 • 193 citations

Curcumin inhibits cell proliferation by interfering with the cell cycle and inducing apoptosis in colon carcinoma cells.

2000 • 188 citations

Curcumin Activates Defensive Genes and Protects Neurons Against Oxidative Stress

2006 • 178 citations

Anatomical integration of newly generated dentate granule neurons following traumatic brain injury in adult rats and its association to cognitive recovery

2007 • 172 citations

Adult neurogenesis in the intact and epileptic dentate gyrus

2007 • 167 citations

p38 MAP Kinase Mediates Nitric Oxide-induced Apoptosis of Neural Progenitor Cells

2001 • 152 citations

RETRACTED: Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines

2006 • 148 citations

Curcumin in Cell Death Processes: A Challenge for CAM of Age‐Related Pathologies

2007 • 133 citations

The effect of streptozotocin-induced diabetes on cell proliferation in the rat dentate gyrus

2000 • 130 citations

Neural stem cells express melatonin receptors and neurotrophic factors: colocalization of the MT1 receptor with neuronal and glial markers.

2004 • 123 citations

Gap junctional communication is required to maintain mouse cortical neural progenitor cells in a proliferative state

2004 • 118 citations

Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease.

2003 • 117 citations

Curcumin protects mitochondria from oxidative damage and attenuates apoptosis in cortical neurons.

2004 • 116 citations

Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation

2007 • 95 citations

Traditional Indian systems of medicine.

2000 • 95 citations

Curcumin attenuates the kainic acid-induced hippocampal cell death in the mice

2007 • 93 citations

Immediate and Delayed Treatments with Curcumin Prevents Forebrain Ischemia-Induced Neuronal Damage and Oxidative Insult in the Rat Hippocampus

2006 • 86 citations

Prevention of kainic acid-induced changes in nitric oxide level and neuronal cell damage in the rat hippocampus by manganese complexes of curcumin and diacetylcurcumin

2005 • 82 citations

Curcumin inhibits trinitrobenzene sulphonic acid-induced colitis in rats by activation of peroxisome proliferator-activated receptor gamma

2006 • 77 citations

Curcumin attenuates glutamate-induced HT22 cell death by suppressing MAP kinase signaling

2006 • 66 citations

Chemoprevention of Colon Cancer by Dietary Curcumin

1995 • 63 citations

Signaling pathways of the early differentiation of neural stem cells by neurotrophin-3

2007 • 46 citations

Curcumin inhibits protease-activated receptor-2 and -4-mediated mast cell activation

2003 • 29 citations

Knockdown of Stat3 in C17.2 neural stem cells facilitates the generation of neurons: a possibility of transplantation with a low level of oncogene

2006 • 17 citations

Oxygen glucose deprivation inhibits the growth and ERK phosphorylation of neural progenitor cells in vitro

2007 • 14 citations