Antidepressant-like effects of a cocoa polyphenolic extract in Wistar–Unilever rats
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References (80)
Free radicals in biology and medicine
1991 • 17,840 citations
Free Radicals in Biology and Medicine
2015 • 8,284 citations
Polyphenols: food sources and bioavailability
2004 • 7,472 citations
Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study
1997 • 7,096 citations
Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study
1993 • 4,414 citations
Depression: a new animal model sensitive to antidepressant treatments
1977 • 4,272 citations
Behavioural despair in rats: A new model sensitive to antidepressant treatments
1978 • 3,035 citations
Vegetables, Fruit, and Cancer Prevention
1996 • 2,157 citations
Flavonoid Intake and Long-term Risk of Coronary Heart Disease and Cancer in the Seven Countries Study
1995 • 1,769 citations
Polyphenols: antioxidants and beyond
2005 • 1,617 citations
Selective Serotonin-Reuptake Inhibitors and Risk of Persistent Pulmonary Hypertension of the Newborn
2006 • 873 citations
Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study
1996 • 708 citations
Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments
2001 • 692 citations
Polyphenols: do they play a role in the prevention of human pathologies?
2002 • 593 citations
Major Depressive Disorder
2000 • 543 citations
Procyanidin dimer B2 [epicatechin-(4β-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa
2002 • 509 citations
Effects of Low Habitual Cocoa Intake on Blood Pressure and Bioactive Nitric Oxide
2007 • 471 citations
Identification of Procyanidins in Cocoa (Theobroma cacao) and Chocolate Using High-Performance Liquid Chromatography/Mass Spectrometry
1999 • 457 citations
Depression: The predisposing influence of stress
1982 • 431 citations
HPLC Method for the Quantification of Procyanidins in Cocoa and Chocolate Samples and Correlation to Total Antioxidant Capacity
1999 • 405 citations
Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study
1995 • 394 citations
Antioxidant enzyme activities and oxidative stress in affective disorders
2004 • 371 citations
Cocoa inhibits platelet activation and function,
2000 • 365 citations
Flavonoids from Hypericum perforatum Show Antidepressant Activity in the Forced Swimming Test
2000 • 364 citations
Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (‐)‐epigallocatechin‐3‐gallate: implications for neurodegenerative diseases
2004 • 356 citations
Procyanidin Content and Variation in Some Commonly Consumed Foods
2000 • 346 citations
A Dose-Response Effect from Chocolate Consumption on Plasma Epicatechin and Oxidative Damage
2000 • 316 citations
Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment
2005 • 314 citations
Adenosine Deaminase, Nitric Oxide, Superoxide Dismutase, and Xanthine Oxidase in Patients with Major Depression: Impact of Antidepressant Treatment
2007 • 300 citations
Rapid recovery from major depression using magnesium treatment
2006 • 273 citations
Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans
2007 • 242 citations
Antioxidative Polyphenols Isolated from Theobroma cacao
1998 • 219 citations
Antidepressant medications: a review of the evidence for drug-induced sexual dysfunction
2002 • 200 citations
Evidence for oxidative stress in the frontal cortex in patients with recurrent depressive disorder—a postmortem study
2007 • 199 citations
Phenolic antioxidants attenuate neuronal cell death following uptake of oxidized low-density lipoprotein
2000 • 185 citations
Body Weight Changes Associated With Psychopharmacology
2002 • 166 citations
Protection against peroxynitrite by cocoa polyphenol oligomers
1999 • 165 citations
Antidepressants: Neurochemical, Behavioral and Clinical Perspectives
1982 • 162 citations
Ingested cocoa can prevent high-fat diet-induced obesity by regulating the expression of genes for fatty acid metabolism
2005 • 150 citations
Potential Therapeutic Properties of Green Tea Polyphenols in Parkinson???s Disease
2003 • 142 citations
Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: Impact of past episodes
2006 • 139 citations
Inhibitory Effects of Cocoa Flavanols and Procyanidin Oligomers on Free Radical-Induced Erythrocyte Hemolysis
2002 • 134 citations
A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review
2001 • 131 citations
The effect of Malaysian cocoa extract on glucose levels and lipid profiles in diabetic rats
2005 • 125 citations
Antidepressant- and anxiolytic-like activity of magnesium in mice
2004 • 123 citations
Depression as a Consequence of Inadequate Neurochemical Adaptation in Response to Stressors
1992 • 121 citations
Acute and chronic effects of flavanol-rich cocoa on vascular function in subjects with coronary artery disease: a randomized double-blind placebo-controlled study
2006 • 118 citations
Dietary supplementation with cacao liquor proanthocyanidins prevents elevation of blood glucose levels in diabetic obese mice
2007 • 118 citations
Antidepressant-like effect of icariin and its possible mechanism in mice
2005 • 111 citations
Antidepressant Activity of Quercetin, a Bioflavonoid, in Streptozotocin-Induced Diabetic Mice
2003 • 111 citations
Possible Role of Nitric Oxide and Adrenomedullin in Bipolar Affective Disorder
2002 • 107 citations
Antidepressant Effects of Apocynum venetum Leaves in a Forced Swimming Test.
2001 • 102 citations
Daily Consumption of a Dark Chocolate Containing Flavanols and Added Sterol Esters Affects Cardiovascular Risk Factors in a Normotensive Population with Elevated Cholesterol
2008 • 99 citations
Endocannabinoids accumulate in spinal cord of SOD1G93A transgenic mice
2004 • 98 citations
Pentameric procyanidin from Theobroma cacao selectively inhibits growth of human breast cancer cells
2005 • 94 citations
Effects of long-term administration of a cocoa polyphenolic extract (Acticoa powder) on cognitive performances in aged rats
2008 • 90 citations
Anxiolytic and antidepressant-like effects of the hydroalcoholic extract from Aloysia polystachya in rats
2005 • 89 citations
Oxidative stress in blood platelets from schizophrenic patients
2005 • 88 citations
Effects of Green Tea Polyphenol on Cognitive and Acetylcholinesterase Activities
2004 • 84 citations
Is the Arginine-Nitric Oxide Pathway Involved in the Pathogenesis of Schizophrenia?
2003 • 83 citations
Antidepressant-Like Effect of Onion (Allium cepaL.) Powder in a Rat Behavioral Model of Depression
2008 • 80 citations
Antidepressant Effect of Extracts from Ginkgo biloba Leaves in Behavioral Models
2006 • 79 citations
Antidepressant-induced hepatotoxicity
2003 • 71 citations
Antidepressant-like effect of Cecropia glazioui Sneth and its constituents – In vivo and in vitro characterization of the underlying mechanism
2007 • 62 citations
The hydroalcoholic extract of Salvia elegans induces anxiolytic- and antidepressant-like effects in rats
2006 • 59 citations
The vasculoprotective effects of flavonoid-rich cocoa and chocolate
2004 • 55 citations
Pharmacological and Endocrine Effects of Hypericum Perforatum and Hypericin After Repeated Treatment
2001 • 45 citations
The changes of oxidative stress and human 8-hydroxyguanine glycosylase1 gene expression in depressive patients with acute leukemia
2006 • 42 citations
Antidepressant-like effect of hyperfoliatin, a polyisoprenylated phloroglucinol derivative from Hypericum perfoliatum (Clusiaceae) is associated with an inhibition of neuronal monoamines uptake
2007 • 39 citations
Preventive Antioxidant Effects of Cocoa Polyphenolic Extract on Free Radical Production and Cognitive Performances after Heat Exposure in Wistar Rats
2007 • 38 citations
Chocolate, well-being and health among elderly men
2007 • 36 citations
Antidepressant and antistress activity of GC‐MS characterized lipophilic extracts of Ginkgo biloba leaves
2007 • 35 citations
Protective effect of polyphenol‐rich extract prepared from Malaysian cocoa (Theobroma cacao) on glucose levels and lipid profiles in streptozotocin‐induced diabetic rats
2008 • 26 citations
Preventive Effects of ACTICOA Powder, a Cocoa Polyphenolic Extract, on Experimentally Induced Prostate Hyperplasia in Wistar-Unilever Rats
2007 • 23 citations
Cocoa flavanols and cardiovascular health
2002 • 23 citations
Therapeutic Effect of ACTICOA Powder, a Cocoa Polyphenolic Extract, on Experimentally Induced Prostate Hyperplasia in Wistar-Unilever Rats
2007 • 22 citations
Protective effect of Acticoa powder, a cocoa polyphenolic extract, on prostate carcinogenesis in Wistar–Unilever rats
2008 • 21 citations
Role of α2 Receptors in Quercetin-Induced Behavioral Despair in Mice
2007 • 20 citations
Effects of Combined Administration of Diazepam and Imipramine Hydrochloride in Rats
1986 • 9 citations
Deleted Work
1955 • 0 citations