Molecular Determinants of Glucocorticoid Receptor Function and Tissue Sensitivity to Glucocorticoids

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis

1992 • 3,026 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation

1995 • 2,525 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

1995 • 2,386 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Steroid hormone receptors: Many Actors in search of a plot

1995 • 1,854 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

Mineralocorticoid Action: Target Tissue Specificity Is Enzyme, Not Receptor, Mediated

1988 • 1,607 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor.

1994 • 1,057 citations

A two-step mechanism for the interaction of estradiol with rat uterus.

1968 • 1,013 citations

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

1987 • 999 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation.

1995 • 926 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

Characterization of Mechanisms Involved in Transrepression of NF-κB by Activated Glucocorticoid Receptors

1995 • 815 citations

Reduced levels of hsp90 compromise steroid receptor action in vivo

1990 • 794 citations

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

1993 • 749 citations

Steroid Hormone Receptors: Interaction with Deoxyribonucleic Acid and Transcription Factors*

1993 • 724 citations

Cloning and tissue distribution of the human 1 lβ-hydroxysteroid dehydrogenase type 2 enzyme

1994 • 707 citations

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

1993 • 668 citations

The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor.

1993 • 652 citations

Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans.

1995 • 636 citations

Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation

1988 • 600 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

1988 • 588 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Dopaminergic and Ligand-Independent Activation of Steroid Hormone Receptors

1991 • 577 citations

A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.

1994 • 527 citations

The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

1988 • 522 citations

Steroid receptors and their associated proteins.

1993 • 513 citations

Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

1987 • 512 citations

Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones.

1996 • 505 citations

Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.

1995 • 487 citations

Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids.

1993 • 457 citations

Nuclear Receptor/AP-1 Interaction*

1993 • 435 citations

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1987 • 428 citations

Mutational Analysis of Hsp90 Function: Interactions with a Steroid Receptor and a Protein Kinase

1995 • 425 citations

Synergistic action of the glucocorticoid receptor with transcription factors.

1988 • 407 citations

The genomic structure of the human glucocorticoid receptor.

1991 • 397 citations

Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy.

1994 • 394 citations

Evidence That the 90-kDa Heat Shock Protein Is Necessary for the Steroid Binding Conformation of the L Cell Glucocorticoid Receptor

1989 • 394 citations

Specific and Nonspecific Physicochemical Interactions of Glucocorticoids and Related Steroids with Rat Thymus Cells in Vitro

1968 • 381 citations

Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.

1991 • 373 citations

Cooperativity of the glucocorticoid receptor and the CACCC-box binding factor

1988 • 370 citations

Intracellular Receptor Concentration Limits Glucocorticoid-Dependent Enhancer Activity*

1987 • 363 citations

Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma.

1995 • 355 citations

Two human homologues ofSaccharomyces cerevisiae SWI2/SNF2andDrosophila brahmaare transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor

1994 • 338 citations

Convergent Pathways for Steroid Hormone- and Neurotransmitter-Induced Rat Sexual Behavior

1994 • 332 citations

Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene.

1993 • 324 citations

Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo.

1995 • 313 citations

Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene

1992 • 313 citations

Abnormalities of glucocorticoid metabolism and the renin???angiotensin system: a four-corners approach to the identification of genetic determinants of blood pressure

1992 • 308 citations

Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids.

1993 • 306 citations

Stress response, adrenal steroid receptor levels and corticosteroid-binding globulin levels — a comparison between Sprague-Dawley, Fischer 344 and Lewis rats

1993 • 294 citations

Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB.

1990 • 290 citations

Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo.

1992 • 282 citations

Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor.

1995 • 272 citations

Emerging diversities in the mechanism of action of steroid hormones

1995 • 265 citations

Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements.

1992 • 246 citations

Phosphorylation of Steroid Hormone Receptors*

1992 • 243 citations

Syndromes of Glucocorticoid Resistance

1993 • 237 citations

Ubiquitous transcription factor OTF-1 mediates induction of the MMTV promoter through synergistic interaction with hormone receptors

1991 • 224 citations

Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene.

1993 • 224 citations

The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids.

1995 • 223 citations

Negative transcriptional regulation of human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT.

1993 • 211 citations

A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development

1995 • 190 citations

Structural determinants of DNA-binding specificity by steroid receptors.

1995 • 190 citations

A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor

1995 • 188 citations

An association between a BclI restriction fragment length polymorphism of the glucocorticoid receptor locus and hyperinsulinaemia in obese women

1992 • 185 citations

Modulation of pair bonding in female prairie voles (Microtus ochrogaster) by corticosterone.

1995 • 178 citations

Glucocorticoid hormone resistance during primate evolution: receptor-mediated mechanisms.

1982 • 178 citations

Proof that hsp70 is required for assembly of the glucocorticoid receptor into a heterocomplex with hsp90.

1994 • 169 citations

Interaction of the TGGCA-binding protein with upstream sequences is required for efficient transcription of mouse mammary tumor virus.

1987 • 168 citations

Bidirectional transport of glucocorticoid receptors across the nuclear envelope.

1993 • 167 citations

Localization of the 90-kDa heat shock protein-binding site within the hormone-binding domain of the glucocorticoid receptor by peptide competition

1991 • 165 citations

Negative regulation of interleukin 2 transcription by the glucocorticoid receptor.

1992 • 164 citations

The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product.

1995 • 163 citations

Modulation of glucocorticoid receptor function by protein kinase A.

1992 • 162 citations

LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones.

1995 • 161 citations

Autoregulation of glucocorticoid receptor gene expression

1991 • 153 citations

Triamcinolone acetonide regulates glucocorticoid-receptor levels by decreasing the half-life of the activated nuclear-receptor form.

1985 • 150 citations

Psychopathology in patients with endogenous Cushing's syndrome: ‘atypical’ or melancholic features

1995 • 147 citations

Novel Antipeptide Antibodies to the Human Glucocorticoid Receptor: Recognition of Multiple Receptor Formsin Vitroand Distinct Localization of Cytoplasmic and Nuclear Receptors

1990 • 140 citations

Potentiation of glucocorticoid receptor-mediated gene expression by the immunophilin ligands FK506 and rapamycin.

1993 • 137 citations

Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3).

1993 • 135 citations

Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate.

1990 • 135 citations

Characterization of regional and gender differences in glucocorticoid receptors and lipoprotein lipase activity in human adipose tissue.

1994 • 131 citations

Evidence that the FK506-binding immunophilin heat shock protein 56 is required for trafficking of the glucocorticoid receptor from the cytoplasm to the nucleus.

1995 • 131 citations

Regulation of the human glucocorticoid receptor by long-term and chronic treatment with glucocorticoid

1994 • 128 citations

Human glucocorticoid receptor cDNA contains sequences sufficient for receptor down-regulation.

1990 • 125 citations

Hepatocyte Nuclear Factor 3 Determines the Amplitude of the Glucocorticoid Response of the Rat Tyrosine Aminotransferase Gene

1995 • 122 citations

Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions.

1994 • 121 citations

Cortisol resistance in acquired immunodeficiency syndrome.

1992 • 120 citations

Nelson's syndrome associated with a somatic frame shift mutation in the glucocorticoid receptor gene.

1996 • 117 citations

Glucocorticoid receptors in rheumatoid arthritis

1992 • 114 citations

The unliganded glucocorticoid receptor is localized in the nucleus, not in the cytoplasm.

1992 • 108 citations

Role of Acidic and Phosphorylated Residues in Gene Activation by the Glucocorticoid Receptor

1995 • 107 citations

Detection of human 11β-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform to renal collecting ducts

1995 • 106 citations

Modulation of cell signaling pathways can enhance or impair glucocorticoid-induced gene expression without altering the state of receptor phosphorylation.

1993 • 105 citations

All of the factors required for assembly of the glucocorticoid receptor into a functional heterocomplex with heat shock protein 90 are preassociated in a self-sufficient protein folding structure, a “foldosome”.

1994 • 102 citations

Intragenic sequences of the human glucocorticoid receptor complementary DNA mediate hormone-inducible receptor messenger RNA down-regulation through multiple mechanisms.

1994 • 101 citations

Structure and function of the glucocorticoid receptor

1993 • 100 citations

The promoter and first, untranslated exon of the human glucocorticoid receptor gene are GC rich but lack consensus glucocorticoid receptor element sites.

1990 • 99 citations

Delineation of a small region within the majortransactivation domain of the human glucocorticoid receptor that mediatestransactivation of gene expression.

1994 • 98 citations

Functional Interference between the Ubiquitous and Constitutive Octamer Transcription Factor 1 (OTF-1) and the Glucocorticoid Receptor by Direct Protein-Protein Interaction Involving the Homeo Subdomain of OTF-1

1992 • 97 citations

Site-directed mutagenesis of the phosphorylation sites in the mouse glucocorticoid receptor.

1993 • 96 citations

Cyclosporin A potentiates the dexamethasone-induced mouse mammary tumor virus-chloramphenicol acetyltransferase activity in LMCAT cells: a possible role for different heat shock protein-binding immunophilins in glucocorticosteroid receptor-mediated gene expression.

1995 • 96 citations

Modulation by vitamin B6 of glucocorticoid receptor-mediated gene expression requires transcription factors in addition to the glucocorticoid receptor.

1993 • 95 citations

Splice site mutation in the glucocorticoid receptor gene causes resistance to glucocorticoid-induced apoptosis in a human acute leukemic cell line.

1995 • 95 citations

Creation of “super” glucocorticoid receptors by point mutations in the steroid binding domain.

1991 • 94 citations

Adrenal steroid receptor binding in spleen and thymus after stress or dexamethasone.

1990 • 89 citations

Molecular mechanism of RU 486 action: a review

1992 • 88 citations

Steroid hormone receptor phosphorylation: is there a physiological role?

1994 • 88 citations

The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor.

1994 • 82 citations

Selectivity of Cell Cycle Regulation of Glucocorticoid Receptor Function

1995 • 82 citations

Modulation of steroid receptor‐mediated gene expression by vitamin B ₆

1994 • 79 citations

Characterization of the Human Glucocorticoid Receptor Promoter

1995 • 79 citations

Identification of the activation-labile gene: a single point mutation in the human glucocorticoid receptor presents as two distinct receptor phenotypes.

1993 • 79 citations

FK506 binding to the 56-kilodalton immunophilin (hsp56) in the glucocorticoid receptor heterocomplex has no effect on receptor folding or function

1993 • 78 citations

Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex

1994 • 78 citations

Interference and synergism of glucocorticoid receptor and octamer factors.

1991 • 77 citations

Effect of Chronic Treatment with the Glucocorticoid Antagonist RU 486 in Man: Toxicity, Immunological, and Hormonal Aspects

1990 • 76 citations

The down side of glucocorticoid receptor regulation

1992 • 75 citations

Functional elements of the steroid hormone-responsive promoter of mouse mammary tumor virus

1990 • 71 citations

Kinetics of glucocorticoid receptor phosphorylation in intact cells. Evidence for hormone-induced hyperphosphorylation after activation and recycling of hyperphosphorylated receptors.

1993 • 71 citations

Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro.

1992 • 69 citations

Potentiation of glucocorticoid receptor-mediated gene expression by heat and chemical shock.

1994 • 68 citations

Higher levels of control: modulation of steroid hormone-regulated gene transcription.

1992 • 67 citations

Human small cell lung cancer cell lines expressing the proopiomelanocortin gene have aberrant glucocorticoid receptor function.

1994 • 65 citations

Subcellular distribution of the glucocorticoid receptor and evidence for its association with microtubules

1995 • 65 citations

Estrogen-Induced Decrease of Glucocorticoid Receptor Messenger Ribonucleic Acid Concentration in Rat Anterior Pituitary Gland

1987 • 63 citations

A Patient with Hypocortisolism and Cushing's Syndrome-Like Manifestations: Cortisol Hyperreactive Syndrome*

1990 • 62 citations

Functional interference between the Spi-1/PU.1 oncoprotein and steroid hormone or vitamin receptors.

1993 • 61 citations

Regulation of Glucocorticoid Receptor Function through Assembly of a Receptor‐Heat Shock Protein Complex^a

1993 • 61 citations

Tissue-specific expression of heat shock proteins 70 and 90: potential implication for differential sensitivity of tissues to glucocorticoids

1993 • 61 citations

Glucocorticoids and Protein Kinase A Coordinately Modulate Transcription Factor Recruitment at a Glucocorticoid-Responsive Unit

1995 • 61 citations

Purification and structural analysis of the modulator of the glucocorticoid-receptor complex. Evidence that modulator is a novel phosphoglyceride.

1988 • 60 citations

Hormone-Independent Repression of AP-1-Inducible Collagenase Promoter Activity by Glucocorticoid Receptors

1995 • 59 citations

A conserved carboxy-terminal subdomain is important for ligand interpretation and transactivation by nuclear receptors.

1994 • 58 citations

Cell cycle-dependent glucocorticoid receptor phosphorylation and activity.

1994 • 57 citations

Thermal activation of the purified rat hepatic glucocorticoid receptor. Evidence for a two-step mechanism.

1985 • 57 citations

Cell-specific bifunctional role of Jun oncogene family members on glucocorticoid receptor-dependent transcription.

1993 • 56 citations

Glucocorticoid regulation of rat whey acidic protein gene expression involves hormone-induced alterations of chromatin structure in the distal promoter region.

1994 • 56 citations

Interplay of steroid hormone receptors and transcription factors on the mouse mammary tumor virus promoter

1992 • 53 citations

The Glucocorticoid Receptor and RU 486 in Man

1995 • 51 citations

Endogenous blockade of 1,25-dihydroxyvitamin D-receptor binding in New World primate cells.

1991 • 49 citations

Unique sequences in the guinea pig glucocorticoid receptor induce constitutive transactivation and decrease steroid sensitivity.

1994 • 49 citations

Glucocorticoid receptors in ATP-depleted cells. Dephosphorylation, loss of hormone binding, HSP90 dissociation, and ATP-dependent cycling.

1994 • 47 citations

Genetic variation of the glucocorticoid receptor from a steroid-resistant primate

1991 • 47 citations

Nucleoprotein Structure Influences the Response of the Mouse Mammary Tumor Virus Promoter to Activation of the Cyclic AMP Signalling Pathway

1995 • 47 citations

Uterine Estrogen and Progesterone Receptors in an Estrogen- and Progesterone-“Resistant” Primate*

1984 • 46 citations

Mutual cross-modulation of steroid/retinoic acid receptor and AP-1 transcription factor activities 1A novel property with practical implications

1994 • 45 citations

Synergistic activation of neurotensin/neuromedin N gene expression by c-Jun and glucocorticoids: novel effects of Fos family proteins.

1995 • 45 citations

Tissue-Specific Dopaminergic Regulation of the Glucocorticoid Receptor in the Rat Pituitary*

1987 • 44 citations

Coordinate regulation of glucocorticoid receptor and c-jun mRNA levels: evidence for cross-talk between two signaling pathways' at the transcriptional level.

1994 • 44 citations

Various modes of gene regulation by nuclear receptors for steroid and thyroid hormones

1993 • 44 citations

Determinants of high-affinity DNA binding by the glucocorticoid receptor: evaluation of receptor domains outside the DNA-binding domain

1992 • 44 citations

Evidence that the modulator of the glucocorticoid-receptor complex is the endogenous molybdate factor.

1988 • 40 citations

A transition in transcriptional activation by the glucocorticoid and retinoic acid receptors at the tumor stage of dermal fibrosarcoma development.

1995 • 38 citations

Hormone binding domain of human glucocorticoid receptor. Enhancement of transactivation function by substitution mutants M565R and A573Q.

1994 • 38 citations

Glucocorticoids and glucocorticoid antagonists: lessons from RU 486.

1988 • 37 citations

Reduced expression of glucocorticoid receptor levels in human osteoarthritic chondrocytes. Role in the suppression of metalloprotease synthesis.

1993 • 35 citations

Concerted Stimulation of Transcription by Glucocorticoid Receptors and Basal Transcription Factors: Limited Transcriptional Synergism Suggests Mediation by Coactivators/Adaptors

1991 • 34 citations

Stabilization in vitro of the untransformed glucocorticoid receptor complex of S49 lymphocytes by the immunophilin ligand FK506

1995 • 34 citations

Glucocorticoid receptors: ATP-dependent cycling and hormone-dependent hyperphosphorylation

1993 • 32 citations

The glucocorticoid receptor and its endogenous regulators.

1990 • 31 citations

Cell to cell contacts control the transcription activity of the glucocorticoid receptor.

1994 • 30 citations

The glucocorticoid receptor functions at multiple steps during transcription initiation by RNA polymerase II.

1994 • 30 citations

Organ-specific actions of 11β-hydroxysteroid dehydrogenase in humans: Implications for the pathophysiology of hypertension

1994 • 30 citations

Molecular Cloning of Rat Liver Glucocorticoid Receptor Translocation Promoter

1993 • 24 citations

Modulation of glucocorticoid induction of stably transfected tyrosine aminotransferase gene constructs involves elements up-stream of the glucocorticoid-responsive element.

1992 • 24 citations

Selective deletions in the 90 kDa heat shock protein (hsp90) impede hetero-oligomeric complex formation with the glucocorticosteroid receptor (GR) or hormone binding by GR

1994 • 24 citations

Relative glucocorticoid potency revisited

1994 • 20 citations

Pharmacology of 11β-hydroxysteroid dehydrogenase

1994 • 20 citations

Steroid hormone receptors selectively affect transcriptional activation but not basal repression by thyroid hormone receptors.

1995 • 20 citations

Morphometric studies of the localization of the glucocorticoid receptor in mammalian cells and of glucocorticoid hormone-induced effects.

1994 • 20 citations

The glucocorticoid receptor and hypertension

1994 • 17 citations

Activation of the human glucocorticoid receptor: Evidence for a two-step model

1988 • 16 citations

Nuclear extracts enhance the interaction of fusion proteins containing the DNA-binding domain of the androgen and glucocorticoid receptor with androgen and glucocorticoid response elements

1994 • 16 citations

A thyroid hormone receptor-dependent glucocorticoid induction.

1994 • 15 citations

Factor-assisted DNA binding as a possible general mechanism for steroid receptors. Functional heterogeneity among activated receptor-steroid complexes

1994 • 15 citations

Expression of hsp90β messenger ribonucleic acid in patients with familial glucocorticoid resistance—Correlation to receptor status

1995 • 14 citations

Nanomolar concentrations of untransformed glucocorticoid receptor in nuclei of intact cells

1994 • 13 citations

Modulator inhibits nuclear translocation of the glucocorticoid receptor and inhibits glucocorticoid-induced apoptosis in the human leukemic cell line CEM C-7.

1995 • 11 citations

The heat-stable cytosolic factor that promotes glucocorticoid receptor binding to DNA is neither thioredoxin nor ribonuclease

1987 • 10 citations

Transcription Activation of Mouse Mammary Tumor Virus-Chloramphenicol Acetyltransferase: A Model To Study the Metabolism of Cortisol

1994 • 10 citations

Human lymphocyte glucocorticoid receptors reside mainly in the cytoplasm

1985 • 9 citations

Glucocorticoid receptor phosphorylation in v-mos-transformed cells

1995 • 7 citations