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Human small cell lung cancer cell lines expressing the proopiomelanocortin gene have aberrant glucocorticoid receptor function.

Data up to Jan 2025

Published1994
Citations65
References35

Total Citations Per Year

Abstract

References (35)

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.

1991 • 373 citations

Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene.

1993 • 324 citations

Clinical and Laboratory Studies of Ectopic Humoral Syndromes

1969 • 278 citations

Signal Transduction and Transcriptional Regulation by Glucocorticoid Receptor-LexA Fusion Proteins

1988 • 268 citations

Glucocorticoid Receptor Binding to a Specific DNA Sequence Is Required for Hormone-Dependent Repression of Pro-Opiomelanocortin Gene Transcription

1989 • 265 citations

Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene.

1993 • 224 citations

A mutation of the glucocorticoid receptor in primary cortisol resistance.

1993 • 217 citations

Identification of a Dominant Negative Form of the Human Estrogen Receptor

1991 • 211 citations

Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription.

1989 • 156 citations

Studies on ectopic ACTH-producing tumors.II. Clinical and biochemical features of 30 cases

1975 • 142 citations

Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene

1993 • 132 citations

Cortisol receptor resistance: the variability of its clinical presentation and response to treatment.

1992 • 128 citations

Variable transcriptional activity and ligand binding of mutant beta 1 3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone.

1992 • 107 citations

Progression to steroid insensitivity can occur irrespective of the presence of functional steroid receptors

1987 • 105 citations

Developmental and hormonal regulation of glucocorticoid receptor messenger RNA in the rat.

1989 • 95 citations

Repression of the Human Glycoprotein Hormone α-Subunit Gene by Glucocorticoids: Evidence for Receptor Interactions with Limiting Transcriptional Activators

1991 • 65 citations

Transcription factor interactions: selectors of positive or negative regulation from a single DNA element

1990 • 55 citations

Defective Glucocorticoid Regulation of Proopiomelanocortin Gene Expression and Peptide Secretion in a Small Cell Lung Cancer Cell Line*

1990 • 44 citations

Pit-1 Binding Sequences Permit Calcium Regulation of Human Prolactin Gene Expression

1991 • 44 citations

Proopiomelanocortin Gene Promoter Elements Required for Constitutive and Glucocorticoid-Repressed Transcription

1991 • 43 citations

Proopiomelanocortin Gene Expression in Normal and Tumoral Human Lung*

1991 • 33 citations

Pro-opiomelanocortin gene expression and peptide secretion in human small-cell lung cancer cell lines

1989 • 27 citations

Glucocorticoid-induced growth inhibition of cells from a human lung alveolar cell carcinoma.

1978 • 22 citations

Glucocorticoid receptors in human malignancies: A review

1991 • 22 citations

Glucocorticoid inhibition of ACTH peptides: small cell lung cancer cell lines are more resistant than pituitary corticotroph adenoma cells

1993 • 16 citations

Proopiomelanocortin gene expression in normal and tumoral human lung

1992 • 3 citations

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Human small cell lung cancer cell lines expressing the proopiomelanocortin gene have… (1994) – Journal of Clinical Investigation | Metascience Observatory Explorer