Human small cell lung cancer cell lines expressing the proopiomelanocortin gene have aberrant glucocorticoid receptor function.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (35)
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.
1982 • 8,069 citations
Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells
1982 • 3,106 citations
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
1987 • 3,057 citations
How eukaryotic transcriptional activators work
1988 • 1,924 citations
CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements
1987 • 1,792 citations
Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
1990 • 1,605 citations
Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
1990 • 1,583 citations
Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element
1990 • 1,326 citations
Functional domains of the human glucocorticoid receptor
1986 • 933 citations
Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.
1991 • 373 citations
Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene.
1993 • 324 citations
Clinical and Laboratory Studies of Ectopic Humoral Syndromes
1969 • 278 citations
Signal Transduction and Transcriptional Regulation by Glucocorticoid Receptor-LexA Fusion Proteins
1988 • 268 citations
Glucocorticoid Receptor Binding to a Specific DNA Sequence Is Required for Hormone-Dependent Repression of Pro-Opiomelanocortin Gene Transcription
1989 • 265 citations
Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene.
1993 • 224 citations
A mutation of the glucocorticoid receptor in primary cortisol resistance.
1993 • 217 citations
Identification of a Dominant Negative Form of the Human Estrogen Receptor
1991 • 211 citations
Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription.
1989 • 156 citations
Studies on ectopic ACTH-producing tumors.II. Clinical and biochemical features of 30 cases
1975 • 142 citations
Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene
1993 • 132 citations
Cortisol receptor resistance: the variability of its clinical presentation and response to treatment.
1992 • 128 citations
Variable transcriptional activity and ligand binding of mutant beta 1 3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone.
1992 • 107 citations
Progression to steroid insensitivity can occur irrespective of the presence of functional steroid receptors
1987 • 105 citations
Developmental and hormonal regulation of glucocorticoid receptor messenger RNA in the rat.
1989 • 95 citations
Repression of the Human Glycoprotein Hormone α-Subunit Gene by Glucocorticoids: Evidence for Receptor Interactions with Limiting Transcriptional Activators
1991 • 65 citations
Transcription factor interactions: selectors of positive or negative regulation from a single DNA element
1990 • 55 citations
Defective Glucocorticoid Regulation of Proopiomelanocortin Gene Expression and Peptide Secretion in a Small Cell Lung Cancer Cell Line*
1990 • 44 citations
Pit-1 Binding Sequences Permit Calcium Regulation of Human Prolactin Gene Expression
1991 • 44 citations
Proopiomelanocortin Gene Promoter Elements Required for Constitutive and Glucocorticoid-Repressed Transcription
1991 • 43 citations
Proopiomelanocortin Gene Expression in Normal and Tumoral Human Lung*
1991 • 33 citations
Pro-opiomelanocortin gene expression and peptide secretion in human small-cell lung cancer cell lines
1989 • 27 citations
Glucocorticoid-induced growth inhibition of cells from a human lung alveolar cell carcinoma.
1978 • 22 citations
Glucocorticoid receptors in human malignancies: A review
1991 • 22 citations
Glucocorticoid inhibition of ACTH peptides: small cell lung cancer cell lines are more resistant than pituitary corticotroph adenoma cells
1993 • 16 citations
Proopiomelanocortin gene expression in normal and tumoral human lung
1992 • 3 citations