Intracellular Receptor Concentration Limits Glucocorticoid-Dependent Enhancer Activity*

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA

1986 • 722 citations

Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region

1983 • 700 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus

1983 • 619 citations

Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.

1966 • 484 citations

Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element

1984 • 449 citations

Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action

1975 • 284 citations

Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding

1984 • 281 citations

Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA.

1977 • 256 citations

The Metabolic Code

1975 • 231 citations

The glucocorticoid domain: Steroid-mediated changes in the rate of synthesis of rat hepatoma proteins

1978 • 227 citations

Glucocorticoid regulation of pro-opiomelanocortin gene transcription in the rat pituitary.

1984 • 218 citations

Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates.

1984 • 202 citations

Dexamethasone regulation of alpha 1-acid glycoprotein and other acute phase reactants in rat liver and hepatoma cells.

1983 • 194 citations

Characterization of the purified activated glucocorticoid receptor from rat liver cytosol.

1984 • 186 citations

Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties.

1985 • 164 citations

Hormonal regulation of the bovine prolactin promoter in rat pituitary tumor cells.

1985 • 147 citations

Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells.

1979 • 120 citations

Isolation of cDNA clones coding for rat tyrosine aminotransferase.

1982 • 111 citations

Evidence for the steroid-induced accumulation of tyrosine-aminotransferase messenger RNA in the absence of protein synthesis.

1968 • 104 citations

Affinity labeling of the rat liver glucocorticoid receptor with dexamethasone 21-mesylate. Identification of covalently labeled receptor by immunochemical methods.

1981 • 101 citations

Infection of cultured rat hepatoma cells by mouse mammary tumor virus

1977 • 91 citations

Monoclonal antibody to the rat glucocorticoid receptor. Relationship between the immunoreactive and DNA-binding domain.

1985 • 88 citations

Isolation of glucocorticoid-unresponsive rat hepatoma cells by fluorescence-activated cell sorting

1980 • 63 citations

The role of enhancers in the regulation of cell-type-specific transcriptional control

1986 • 52 citations

Characterization of the rat liver glucocorticoid receptor purified by DNA-cellulose and ligand affinity chromatography.

1984 • 45 citations

Integration and Activity of Mammary Tumor Virus Genes: Regulation by Hormone Receptors and Chromosomal Position

1981 • 37 citations

A Distinct Glucocorticoid Hormone Response Regulates Phosphoprotein Maturation in Rat Hepatoma Cells

1986 • 26 citations

Viral and cellular transcription enhancers.

1985 • 22 citations

Synthesis and Regulation of Receptors for Polypeptide Hormones

1984 • 6 citations