Creation of “super” glucocorticoid receptors by point mutations in the steroid binding domain.

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

1987 • 999 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA

1986 • 722 citations

Steroid–Cell Interactions

1974 • 592 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cells

1986 • 408 citations

The mouse glucocorticoid receptor: mapping of functional domains by cloning, sequencing and expression of wild-type and mutant receptor proteins.

1986 • 392 citations

Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.

1991 • 373 citations

Specific Cytoplasmic Glucocorticoid Hormone Receptors in Hepatoma Tissue Culture Cells

1971 • 328 citations

Receptors for Reproductive Hormones

1973 • 318 citations

Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor.

1987 • 299 citations

Characterization of a Monoclonal Antibody to the Rat Liver Glucocorticoid Receptor*

1984 • 263 citations

Down-regulation and Phosphorylation of Glucocorticoid Receptors in Cultured Cells

1989 • 223 citations

Steroid hormone receptors : structure and function

1983 • 210 citations

Dexamethasone 21-mesylate: an affinity label of glucocorticoid receptors from rat hepatoma tissue culture cells.

1981 • 190 citations

Harrison's Principles of Internal Medicine

1987 • 149 citations

Identification of cysteine 656 as the amino acid of hepatoma tissue culture cell glucocorticoid receptors that is covalently labeled by dexamethasone 21-mesylate.

1987 • 125 citations

Arsenite and cadmium(II) as probes of glucocorticoid receptor structure and function.

1990 • 118 citations

Steroid Binding Activity Is Retained in a 16-kDa Fragment of the Steroid Binding Domain of Rat Glucocorticoid Receptors

1989 • 75 citations

Structurally based, selective interaction of arsenite with steroid receptors.

1990 • 75 citations

11β-substituted steroids, an original pathway to antihormones

1988 • 62 citations

Chemical Probes of Amino Acid Residues Affect the Active Sites of the Glucocorticoid Receptor*

1980 • 55 citations

Anti-inflammatory pyrazolo-steroids: Potent glucocorticoids containing bulky a-ring substituents and no C3-carbonyl

1979 • 52 citations

Steroid binding to hepatoma tissue culture cell glucocorticoid receptors involves at least two sulfhydryl groups.

1988 • 49 citations

Identification of cysteine-644 as the covalent site of attachment of dexamethasone 21-mesylate to murine glucocorticoid receptors in WEHI-7 cells

1988 • 46 citations

Comparison of DNA binding properties of activated, covalent and noncovalent glucocorticoid receptor-steroid complexes from HTC cells

1984 • 38 citations

Selective covalent labeling of cysteines in bovine serum albumin and in hepatoma tissue culture cell glucocorticoid receptors by dexamethasone 21-mesylate.

1987 • 38 citations

Radiosequence analysis of the human progestin receptor charged with [3H]promegestone. A comparison with the glucocorticoid receptor.

1990 • 35 citations

GlucocorticoidVersusAntiglucocorticoid Activity: Can a Single Functional Group Modification of Glucocorticoid Steroids Always Convey Antiglucocorticoid Activity?

1984 • 34 citations

Association of heat shock protein 90 with the 16 kDa steroid binding core fragment of rat glucocorticoid receptors

1991 • 28 citations

Localization of the Vicinal Dithiols Involved in Steroid Binding to the Rat Glucocorticoid Receptor

1990 • 23 citations