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Lipid rafts and signal transduction

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Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

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Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts

2000 • 2,321 citations

Mechanisms of intracellular protein transport

1994 • 2,280 citations

THE CAVEOLAE MEMBRANE SYSTEM

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Functions of Ceramide in Coordinating Cellular Responses to Stress

1996 • 1,620 citations

ENDOCYTOSIS AND MOLECULAR SORTING

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Lipid sorting in epithelial cells

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The function of sterols in membranes

1976 • 1,330 citations

GPI-anchored proteins are organized in submicron domains at the cell surface

1998 • 1,207 citations

Lipid Domain Structure of the Plasma Membrane Revealed by Patching of Membrane Components

1998 • 1,193 citations

Protein Sorting by Transport Vesicles

1996 • 1,168 citations

Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme

1991 • 1,094 citations

Phases and phase transitions of the phosphatidylcholines

1998 • 1,077 citations

The asymmetric distribution of phospholipids in the human red cell membrane. A combined study using phospholipases and freeze-etch electron microscopy

1973 • 1,052 citations

Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains

1996 • 1,006 citations

Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-1

1998 • 1,003 citations

Sphingolipid–Cholesterol Rafts Diffuse as Small Entities in the Plasma Membrane of Mammalian Cells

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Structure and Origin of Ordered Lipid Domains in Biological Membranes

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VIP21/caveolin is a cholesterol-binding protein.

1995 • 892 citations

Studies on lecithin-cholesterol-water interactions by differential scanning calorimetry and X-ray diffraction

1968 • 891 citations

MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine

1996 • 863 citations

Cholesterol and the Golgi Apparatus

1993 • 819 citations

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

1994 • 793 citations

A detergent-free method for purifying caveolae membrane from tissue culture cells.

1995 • 732 citations

Lipid intermolecular hydrogen bonding: influence on structural organization and membrane function

1987 • 729 citations

Compartmental specificity of cellular membrane fusion encoded in SNARE proteins

2000 • 692 citations

On the Origin of Sphingolipid/Cholesterol-Rich Detergent-Insoluble Cell Membranes: Physiological Concentrations of Cholesterol and Sphingolipid Induce Formation of a Detergent-Insoluble, Liquid-Ordered Lipid Phase in Model Membranes

1997 • 661 citations

Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis

1994 • 646 citations

Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain

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Enzymac characterization and lipid composition of rat liver subcellular membranes

1971 • 643 citations

Role of Lipid Modifications in Targeting Proteins to Detergent-resistant Membrane Rafts

1999 • 626 citations

Hydrophobic mismatch between proteins and lipids in membranes

1998 • 605 citations

Kinetic Analysis of Secretory Protein Traffic and Characterization of Golgi to Plasma Membrane Transport Intermediates in Living Cells

1998 • 603 citations

Myelination in the Absence of Galactocerebroside and Sulfatide: Normal Structure with Abnormal Function and Regional Instability

1996 • 601 citations

Membrane microdomains and caveolae

1999 • 580 citations

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs

1994 • 574 citations

Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy

2000 • 572 citations

Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane

2000 • 557 citations

Cholesterol Is Required for Surface Transport of Influenza Virus Hemagglutinin

1998 • 555 citations

Microdomains of GPI-anchored proteins in living cells revealed by crosslinking

1998 • 555 citations

Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast

2000 • 550 citations

Caveolae and caveolins

1996 • 549 citations

VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles.

1992 • 544 citations

The rate of bulk flow from the endoplasmic reticulum to the cell surface

1987 • 542 citations

Serine Palmitoyltransferase Is the Primary Target of a Sphingosine-like Immunosuppressant, ISP-1/Myriocin

1995 • 537 citations

Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase

1998 • 528 citations

New Perspectives on Mechanisms Involved in Generating Epithelial Cell Polarity

1999 • 522 citations

Sorting and storage during secretory granule biogenesis: looking backward and looking forward

1998 • 516 citations

The differential miscibility of lipids as the basis for the formation of functional membrane rafts

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Plasma Membranes Contain Half the Phospholipid and 90% of the Cholesterol and Sphingomyelin in Cultured Human Fibroblasts

1989 • 509 citations

A Novel Clathrin Adaptor Complex Mediates Basolateral Targeting in Polarized Epithelial Cells

1999 • 509 citations

Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae.

1994 • 506 citations

Golgi dispersal during microtubule disruption: regeneration of Golgi stacks at peripheral endoplasmic reticulum exit sites.

1996 • 498 citations

Sphingolipid organization in biomembranes: what physical studies of model membranes reveal

1998 • 484 citations

Electrospray Ionization Tandem Mass Spectrometry (Esi-Ms/Ms) Analysis of the Lipid Molecular Species Composition of Yeast Subcellular Membranes Reveals Acyl Chain-Based Sorting/Remodeling of Distinct Molecular Species En Route to the Plasma Membrane

1999 • 482 citations

A vital role for glycosphingolipid synthesis during development and differentiation

1999 • 482 citations

Separation of Caveolae from Associated Microdomains of GPI-Anchored Proteins

1995 • 481 citations

A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells.

1989 • 478 citations

ELO2 and ELO3, Homologues of theSaccharomyces cerevisiae ELO1 Gene, Function in Fatty Acid Elongation and Are Required for Sphingolipid Formation

1997 • 471 citations

Lipid Traffic in Animal Cells

1989 • 468 citations

The concept of lipid domains in membranes.

1982 • 466 citations

N-glycans as apical sorting signals in epithelial cells

1995 • 454 citations

Distribution of a Glycosylphosphatidylinositol-anchored Protein at the Apical Surface of MDCK Cells Examined at a Resolution of <100 Å Using Imaging Fluorescence Resonance Energy Transfer

1998 • 452 citations

Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells.

1987 • 443 citations

Kinase Suppressor of Ras Is Ceramide-Activated Protein Kinase

1997 • 440 citations

High-Resolution FRET Microscopy of Cholera Toxin B-Subunit and GPI-anchored Proteins in Cell Plasma Membranes

2000 • 427 citations

Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles

1997 • 427 citations

Molecular arrangements in sphingolipids Conformation and hydrogen bonding of ceramide and their implication on membrane stability and permeability

1976 • 419 citations

Intracellular cholesterol transport

1999 • 416 citations

Procollagen Traverses the Golgi Stack without Leaving the Lumen of Cisternae

1998 • 406 citations

Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects

1999 • 396 citations

Sphingolipid Synthesis as a Target for Antifungal Drugs

1997 • 396 citations

Functional Role of Glycosphingolipids in Cell Recognition and Signaling

1995 • 393 citations

Molecular Cloning of Human Plasma Membrane Phospholipid Scramblase

1997 • 389 citations

CALORIMETRIC EVIDENCE FOR THE LIQUID-CRYSTALLINE STATE OF LIPIDS IN A BIOMEMBRANE

1969 • 386 citations

Sphingolipids—Their Metabolic Pathways and the Pathobiochemistry of Neurodegenerative Diseases

1999 • 384 citations

An investigation of the role of transmembrane domains in Golgi protein retention.

1995 • 384 citations

Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line.

1988 • 381 citations

Endocytic Sorting of Lipid Analogues Differing Solely in the Chemistry of Their Hydrophobic Tails

1999 • 378 citations

Mechanism of Membrane Anchoring Affects Polarized Expression of Two Proteins in MDCK Cells

1989 • 377 citations

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system.

1996 • 371 citations

Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus.

1990 • 369 citations

Structure des phases liquide-cristallines de différents phospholipides, monoglycérides, sphingolipides, anhydres ou en présence d'eau

1967 • 368 citations

Functionally different GPI proteins are organized in different domains on the neuronal surface

1999 • 363 citations

Caveolin Is Palmitoylated on Multiple Cysteine Residues

1995 • 356 citations

Infusion of α-galactosidase A reduces tissue globotriaosylceramide storage in patients with Fabry disease

2000 • 349 citations

Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver.

1992 • 343 citations

Prevention of Lysosomal Storage in Tay-Sachs Mice Treated with N -Butyldeoxynojirimycin

1997 • 339 citations

Functional breakdown of the lipid bilayer of the myelin membrane in central and peripheral nervous system by disrupted galactocerebroside synthesis

1996 • 335 citations

Three-dimensional high-resolution particle tracking for optical tweezers by forward scattered light

1999 • 330 citations

Golgi Membranes Are Absorbed into and Reemerge from the ER during Mitosis

1999 • 329 citations

Recycling of Golgi-resident Glycosyltransferases through the ER Reveals a Novel Pathway and Provides an Explanation for Nocodazole-induced Golgi Scattering

1998 • 326 citations

Correlative Light-Electron Microscopy Reveals the Tubular-Saccular Ultrastructure of Carriers Operating between Golgi Apparatus and Plasma Membrane

2000 • 325 citations

Association of Sterol- and Glycosylphosphatidylinositol-linked Proteins with Drosophila Raft Lipid Microdomains

1999 • 320 citations

Vesicular Tubular Clusters between the ER and Golgi Mediate Concentration of Soluble Secretory Proteins by Exclusion from COPI-Coated Vesicles

1999 • 320 citations

A quantitative analysis of the endocytic pathway in baby hamster kidney cells.

1989 • 315 citations

Combined influence of cholesterol and synthetic amphiphillic peptides upon bilayer thickness in model membranes

1992 • 309 citations

Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions

1992 • 306 citations

Cholesterol-induced fluid-phase immiscibility in membranes.

1991 • 305 citations

Spin labels as enzyme substrates Heterogeneous lipid distribution in liver microsomal membranes

1973 • 303 citations

Transient Confinement of a Glycosylphosphatidylinositol-Anchored Protein in the Plasma Membrane

1997 • 303 citations

Stepwise assembly of functionally active transport vesicles

1993 • 298 citations

Characterization of Ceramide Synthesis

1997 • 297 citations

Sequences within and adjacent to the transmembrane segment of alpha-2,6-sialyltransferase specify Golgi retention.

1991 • 296 citations

Cloning and characterization of the mammalian brain-specific, Mg ²⁺ -dependent neutral sphingomyelinase

2000 • 296 citations

The role of n-glycans in the secretory pathway

1995 • 295 citations

Involvement of Yeast Sphingolipids in the Heat Stress Response of Saccharomyces cerevisiae

1997 • 294 citations

Coupling of Coat Assembly and Vesicle Budding to Packaging of Putative Cargo Receptors

1999 • 293 citations

Assembly of Myelin by Association of Proteolipid Protein with Cholesterol- and Galactosylceramide-Rich Membrane Domains

2000 • 292 citations

AP-4, a Novel Protein Complex Related to Clathrin Adaptors

1999 • 292 citations

Phospholipid class and fatty acid composition of Golgi apparatus isolated from rat liver and comparison with other cell fractions

1970 • 292 citations

New insights in glycosphingolipid function: "glycosignaling domain," a cell surface assembly of glycosphingolipids with signal transducer molecules, involved in cell adhesion coupled with signaling

1998 • 291 citations

Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases

1999 • 288 citations

Separation of “Glycosphingolipid Signaling Domain” from Caveolin-containing Membrane Fraction in Mouse Melanoma B16 Cells and Its Role in Cell Adhesion Coupled with Signaling

1998 • 284 citations

Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver

1991 • 282 citations

Import of lipids into mitochondria

1997 • 275 citations

On the chemistry and occurrence of sphingolipid long-chain bases

1970 • 271 citations

Dissection of a single round of vesicular transport: Sequential intermediates for intercisternal movement in the Golgi stack

1989 • 269 citations

Cloned mammalian neutral sphingomyelinase: Functions in sphingolipid signaling?

1998 • 267 citations

Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N -butyldeoxynojirimycin

1999 • 263 citations

Sorting of endogenous plasma membrane proteins occurs from two sites in cultured human intestinal epithelial cells (Caco-2)

1990 • 262 citations

Hydroxylation of Saccharomyces cerevisiae Ceramides Requires Sur2p and Scs7p

1997 • 260 citations

Dual-color visualization of trans-Golgi network to plasma membrane traffic along microtubules in living cells

1999 • 258 citations

Localization of proteins to the Golgi apparatus

1998 • 257 citations

A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin.

1991 • 257 citations

SPHINGOLIPID FUNCTIONS INSACCHAROMYCES CEREVISIAE: Comparison to Mammals

1998 • 257 citations

N-Glycans Mediate the Apical Sorting of a Gpi-Anchored, Raft-Associated Protein in Madin-Darby Canine Kidney Cells

1999 • 247 citations

Glycosphingolipid-enriched, detergent-insoluble complexes in protein sorting in epithelial cells

1993 • 246 citations

Molecular Cloning and Characterization of a Full-length Complementary DNA Encoding Human Acid Ceramidase

1996 • 244 citations

Sphingoid base 1-phosphate phosphatase: A key regulator of sphingolipid metabolism and stress response

1998 • 244 citations

Phase equilibriums in binary mixtures of phosphatidylcholine and cholesterol

1981 • 243 citations

Lipid dynamics and lipid-protein interactions in rat enterocyte basolateral and microvillus membranes

1980 • 243 citations

Retention and retrieval in the endoplasmic reticulum and the Golgi apparatus

1994 • 243 citations

Sphingolipids Are Potential Heat Stress Signals inSaccharomyces

1997 • 242 citations

Raft association of SNAP receptors acting in apical trafficking in Madin–Darby canine kidney cells

1999 • 242 citations

Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae

2000 • 241 citations

Different biosynthetic transport routes to the plasma membrane in BHK and CHO cells.

1996 • 238 citations

The Debate about Transport in the Golgi—Two Sides of the Same Coin?

2000 • 236 citations

The BST1 Gene of Saccharomyces cerevisiaeIs the Sphingosine-1-phosphate Lyase

1997 • 235 citations

Polarized sorting of glypiated proteins in hippocampal neurons

1991 • 233 citations

Condensed complexes, rafts, and the chemical activity of cholesterol in membranes

2000 • 233 citations

VIP36, a novel component of glycolipid rafts and exocytic carrier vesicles in epithelial cells.

1994 • 232 citations

The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis.

1994 • 228 citations

Retrograde Transport of Golgi-localized Proteins to the ER

1998 • 228 citations

Biogenetic pathways of plasma membrane proteins in Caco-2, a human intestinal epithelial cell line.

1990 • 228 citations

Evidence for Segregation of Sphingomyelin and Cholesterol during Formation of Copi-Coated Vesicles

2000 • 227 citations

1-Palmitoyl-2-pyrenedecanoyl glycerophospholipids as membrane probes: evidence for regular distribution in liquid-crystalline phosphatidylcholine bilayers

1985 • 226 citations

Mice Expressing Only Monosialoganglioside GM3 Exhibit Lethal Audiogenic Seizures

2001 • 226 citations

Heterogeneous distribution of filipin--cholesterol complexes across the cisternae of the Golgi apparatus.

1981 • 225 citations

Cholesterol at Different Bilayer Concentrations Can Promote or Antagonize Lateral Segregation of Phospholipids of Differing Acyl Chain Length

1996 • 224 citations

Influence of molecular packing and phospholipid type on rates of cholesterol exchange

1988 • 223 citations

Neuronal polarity: Essential role of protein–lipid complexes in axonal sorting

1998 • 222 citations

Glucosylceramide synthase and glycosphingolipid synthesis

1998 • 220 citations

Phase transitions of phospholipid bilayers and membranes of Acholeplasma laidlawii B visualized by freeze fracturing electron microscopy

1972 • 218 citations

GTP hydrolysis by arf-1 mediates sorting and concentration of Golgi resident enzymes into functional COP I vesicles

1999 • 213 citations

Carbohydrate-mediated Golgi to cell surface transport and apical targeting of membrane proteins

1998 • 212 citations

IUPAC‐IUB Joint Commission on Biochemical Nomenclature (JCBN) Nomenclature of glycolipids

1998 • 212 citations

Stress signals for apoptosis: ceramide and c-Jun kinase

1998 • 211 citations

Hierarchy of mechanisms involved in generating Na/K-ATPase polarity in MDCK epithelial cells.

1995 • 211 citations

Human acid sphingomyelinase. Isolation, nucleotide sequence and expression of the full-length and alternatively spliced cDNAs

1991 • 210 citations

Role of a New Mammalian Gene Family in the Biosynthesis of Very Long Chain Fatty Acids and Sphingolipids

2000 • 207 citations

Differential extractability of influenza virus hemagglutinin during intracellular transport in polarized epithelial cells and nonpolar fibroblasts.

1989 • 204 citations

SNARE-Mediated Retrograde Traffic from the Golgi Complex to the Endoplasmic Reticulum

1996 • 201 citations

Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes

1998 • 200 citations

Transmembrane domain of influenza virus neuraminidase, a type II protein, possesses an apical sorting signal in polarized MDCK cells

1996 • 198 citations

The Saccharomyces cerevisiae TSC10/YBR265w Gene Encoding 3-Ketosphinganine Reductase Is Identified in a Screen for Temperature-sensitive Suppressors of the Ca2+-sensitive csg2Δ Mutant

1998 • 197 citations

Sphingosine 1-Phosphate-induced Cell Proliferation, Survival, and Related Signaling Events Mediated by G Protein-coupled Receptors Edg3 and Edg5

2000 • 196 citations

Immunoisolation and partial characterization of endothelial plasmalemmal vesicles (caveolae).

1997 • 195 citations

The Dynamics of Golgi Protein Traffic Visualized in Living Yeast Cells

1998 • 191 citations

Ceramide in apoptosis—does it really matter?

1998 • 189 citations

Cytomembrane Differentiation in the Endoplasmic Reticulum-Golgi Apparatus-Vesicle Complex

1968 • 187 citations

Sphingomyelin is synthesized in the cis Golgi

1990 • 187 citations

Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids

1991 • 185 citations

The LCB4 (YOR171c) and LCB5(YLR260w) Genes of Saccharomyces Encode Sphingoid Long Chain Base Kinases

1998 • 184 citations

Covalently bound ω-hydroxyacylsphingosine in the stratum corneum

1987 • 184 citations

Mammalian Cell Mutants Resistant to a Sphingomyelin-directed Cytolysin

1998 • 181 citations

The protein machinery of vesicle budding and fusion

1996 • 181 citations

Synthesis of Mannose-(inositol-P)2-ceramide, the Major Sphingolipid in Saccharomyces cerevisiae, Requires the IPT1 (YDR072c) Gene

1997 • 180 citations

UDP-Galactose:Ceramide Galactosyltransferase Is a Class I Integral Membrane Protein of the Endoplasmic Reticulum

1998 • 179 citations

Structure and cohesive properties of sphingomyelin/cholesterol bilayers

1992 • 179 citations

Cloning of an Alkaline Ceramidase from Saccharomyces cerevisiae

2000 • 178 citations

Sphingosine 1-phosphate: a prototype of a new class of second messengers

1999 • 176 citations

A suppressor gene that enables Saccharomyces cerevisiae to grow without making sphingolipids encodes a protein that resembles an Escherichia coli fatty acyltransferase.

1993 • 176 citations

Interaction of Cholesterol with Sphingomyelins and Acyl-Chain-Matched Phosphatidylcholines: A Comparative Study of the Effect of the Chain Length

1999 • 176 citations

Long-Range Order in Biomembranes

1977 • 175 citations

The phosphoinositol sphingolipids of Saccharomyces cerevisiae are highly localized in the plasma membrane

1991 • 173 citations

Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression.

1993 • 172 citations

Transport of vesicular stomatitis virus G protein to the cell surface is signal mediated in polarized and nonpolarized cells.

1996 • 171 citations

Genetic Evidence for ATP-dependent Endoplasmic Reticulum-to-Golgi Apparatus Trafficking of Ceramide for Sphingomyelin Synthesis in Chinese Hamster Ovary Cells

1999 • 169 citations

Lipids of the Golgi membrane

1998 • 168 citations

Identification of the First Mammalian Sphingosine Phosphate Lyase Gene and Its Functional Expression in Yeast

1998 • 168 citations

Intracellular transport of GPI-anchored proteins

2000 • 167 citations

Lipid components of two different regions of an intestinal epithelial cell membrane of mouse

1974 • 167 citations

Glycans in post-Golgi apical targeting: sorting signals or structural props?

1999 • 166 citations

Molecular arrangements of sphingolipids. The monolayer behaviour of ceramides

1977 • 165 citations

IUPAC-IUB Joint Commission on Biochemical Nomenclature (JCBN)

1983 • 165 citations

Sphingomyelin-enriched Microdomains at the Golgi Complex

2001 • 165 citations

The MAL Proteolipid Is Necessary for Normal Apical Transport and Accurate Sorting of the Influenza Virus Hemagglutinin in Madin-Darby Canine Kidney Cells

1999 • 164 citations

Phases and phase transitions of the sphingolipids

1995 • 163 citations

Sterol partitioning among intracellular membranes. Testing a model for cellular sterol distribution.

1983 • 163 citations

Inositol Phosphorylceramide Synthase Is Located in the Golgi Apparatus ofSaccharomyces cerevisiae

2000 • 161 citations

Localization, Dynamics, and Protein Interactions Reveal Distinct Roles for ER and Golgi SNAREs

1998 • 161 citations

Lateral organisation of membrane lipids

1999 • 161 citations

Transmembrane domain-dependent sorting of proteins to the ER and plasma membrane in yeast

1997 • 161 citations

The Discovery of Australifungin, a Novel Inhibitor of Sphinganine N-Acyltransferase from Sporormiella australis. Producing Organism, Fermentation, Isolation, and Biological Activity.

1995 • 161 citations

Omega-Hydroxyceramides are Required for Corneocyte Lipid Envelope (CLE) Formation and Normal Epidermal Permeability Barrier Function

2000 • 160 citations

Enzyme and phospholipid asymmetry in liver microsomal membranes.

1977 • 159 citations

Identification of ISC1 (YER019w) as Inositol Phosphosphingolipid Phospholipase C inSaccharomyces cerevisiae

2000 • 159 citations

Sphingolipid transport in eukaryotic cells

2000 • 159 citations

O-linked glycans mediate apical sorting of human intestinal sucrase-isomaltase through association with lipid rafts

1999 • 158 citations

Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus

1995 • 157 citations

Identification and Characterization of Saccharomyces cerevisiae Dihydrosphingosine-1-phosphate Phosphatase

1997 • 154 citations

Sphingolipids are essential for the growth of Chinese hamster ovary cells. Restoration of the growth of a mutant defective in sphingoid base biosynthesis by exogenous sphingolipids.

1992 • 152 citations

Lipid composition of the isolated rat intestinal microvillus membrane

1968 • 150 citations

Participation of soluble liver proteins in the exchange of membrane phospholipids

1969 • 150 citations

Cloning and Characterization of a Saccharomyces cerevisiae Alkaline Ceramidase with Specificity for Dihydroceramide

2000 • 148 citations

Myelin glycolipids and their functions

1997 • 148 citations

A functional barrier to movement of lipids in polarized neurons

1992 • 147 citations

Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae

1999 • 147 citations

Internalization and sorting of a fluorescent analogue of glucosylceramide to the Golgi apparatus of human skin fibroblasts: utilization of endocytic and nonendocytic transport mechanisms.

1994 • 147 citations

A mouse B16 melanoma mutant deficient in glycolipids.

1994 • 146 citations

Topology of glucosylceramide synthesis in Golgi membranes from porcine submaxillary glands

1986 • 143 citations

Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters

1999 • 141 citations

Sphingolipids with inositolphosphate-containing head groups.

1993 • 140 citations

LIPID COMPOSITION OF MYELIN FROM THE PERIPHERAL NERVOUS SYSTEM

1967 • 138 citations

The VRG4 Gene Is Required for GDP-mannose Transport into the Lumen of the Golgi in the Yeast, Saccharomyces cerevisiae

1997 • 137 citations

Mutational analysis of the Golgi retention signal of bovine beta-1,4-galactosyltransferase

1993 • 137 citations

Protein-mediated phospholipid translocation in the endoplasmic reticulum with a low lipid specificity

1990 • 136 citations

How lipids interact with an intrinsic membrane protein: the case of the calcium pump

1998 • 136 citations

Characterization of a novel, potent, and specific inhibitor of serine palmitoyltransferase.

1992 • 135 citations

Plasticity in epithelial cell phenotype: modulation by expression of different cadherin cell adhesion molecules.

1995 • 135 citations

Involvement of Long Chain Fatty Acid Elongation in the Trafficking of Secretory Vesicles in Yeast

1998 • 135 citations

Lipid microdomains in dimyristoylphosphatidylcholine–ceramide liposomes

1997 • 134 citations

Subcellular localization of Forssman glycolipid in epithelial MDCK cells by immuno-electronmicroscopy after freeze-substitution.

1991 • 134 citations

Analysis of Phosphorylated Sphingolipid Long-Chain Bases Reveals Potential Roles in Heat Stress and Growth Control in Saccharomyces

1999 • 133 citations

Khafrefungin, a Novel Inhibitor of Sphingolipid Synthesis

1997 • 133 citations

SUR1 (CSG1 / BCL21), a gene necessary for growth of Saccharomyces cerevisiae in the presence of high Ca2+ concentrations at 37° C, is required for mannosylation of inositolphosphorylceramide

1997 • 133 citations

Purification, cDNA Cloning, and Expression of UDP-Gal: Glucosylceramide β-1,4-Galactosyltransferase from Rat Brain

1998 • 131 citations

Demonstration of the existence of a second, non-lysosomal glucocerebrosidase that is not deficient in Gaucher disease

1993 • 129 citations

Neuronal Polarity

1999 • 129 citations

Maturation of the axonal plasma membrane requires upregulation of sphingomyelin synthesis and formation of protein-lipid complexes

1999 • 128 citations

The sphingolipid composition of bovine kidney cortex, medulla and papilla

1973 • 128 citations

Evidence for the existence of ganglioside-enriched plasma membrane domains in human peripheral lymphocytes

1997 • 127 citations

Functional Organization of the Golgi Apparatus in Glycosphingolipid Biosynthesis

1998 • 127 citations

Uncoupling of ganglioside biosynthesis by Brefeldin A.

1990 • 124 citations

Phospholipid composition of membranes in the tumor cell

1970 • 123 citations

Preparation and characterization of the lateral and basal plasma membranes of the rat intestinal epithelial cell

1972 • 123 citations

Mutant strains of Saccharomyces cerevisiae lacking sphingolipids synthesize novel inositol glycerophospholipids that mimic sphingolipid structures.

1993 • 123 citations

The Transmembrane Domain of a Carboxyl-terminal Anchored Protein Determines Localization to the Endoplasmic Reticulum

1997 • 122 citations

Renal cortical brush-border and basolateral membranes: Cholesterol and phospholipid Composition and relative turnover

1985 • 121 citations

Getting through the Golgi complex

1998 • 121 citations

GPI-anchored proteins, glycosphingolipids, and sphingomyelin are sequestered to caveolae only after crosslinking.

1996 • 121 citations

Targeting of protein ERGIC-53 to the ER/ERGIC/cis-Golgi recycling pathway.

1995 • 120 citations

The fraction of the lipid in a biological membrane that is in a fluid state: A spin label assay

1972 • 119 citations

The isolation and characterization of a mutant strain of Saccharomyces cerevisiae that requires a long chain base for growth and for synthesis of phosphosphingolipids.

1983 • 118 citations

Protein Sorting by Directed Maturation of Golgi Compartments

1999 • 117 citations

Characterization, quantification and subcellular localization of inositol‐containing sphingolipids of the yeast, Saccharomyces cerevisiae

1994 • 116 citations

Role of Vesicle-Associated Syntaxin 5 in the Assembly of Pre-Golgi Intermediates

1998 • 116 citations

Molecular Characterization of Caveolin Association with the Golgi Complex: Identification of a Cis-Golgi Targeting Domain in the Caveolin Molecule

1999 • 115 citations

Anterograde flow of cargo across the Golgi stack potentially mediated via bidirectional “percolating” COPI vesicles

2000 • 114 citations

Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells.

1993 • 113 citations

Tyrosine-based Membrane Protein Sorting Signals Are Differentially Interpreted by Polarized Madin-Darby Canine Kidney and LLC-PK1 Epithelial Cells

1998 • 113 citations

Transport of newly synthesized glucosylceramide to the plasma membrane by a non-Golgi pathway.

1994 • 112 citations

Rustmicin, a Potent Antifungal Agent, Inhibits Sphingolipid Synthesis at Inositol Phosphoceramide Synthase

1998 • 112 citations

Modulation of Ganglioside Biosynthesis in Primary Cultured Neurons

1989 • 111 citations

Transverse asymmetry of phospholipids in subcellular membranes of rat liver

1977 • 110 citations

The lipids of the plasma membranes and endoplasmic reticulum from cultured baby hamster kidney cells (BHK21)

1972 • 109 citations

Lipid Traffic: The ABC of Transbilayer Movement

2000 • 109 citations

The MAL Proteolipid Is Necessary for the Overall Apical Delivery of Membrane Proteins in the Polarized Epithelial Madin–Darby Canine Kidney and Fischer Rat Thyroid Cell Lines

2000 • 109 citations

Cig30, a Mouse Member of a Novel Membrane Protein Gene Family, Is Involved in the Recruitment of Brown Adipose Tissue

1997 • 109 citations

Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity.

1994 • 109 citations

Model for the structure of the lipid bilayer.

1991 • 108 citations

Ultrafast Glycerophospholipid-selective Transbilayer Motion Mediated by a Protein in the Endoplasmic Reticulum Membrane

1996 • 108 citations

Requirement of Seminolipid in Spermatogenesis Revealed by UDP-galactose:Ceramide Galactosyltransferase-deficient Mice

2000 • 108 citations

Throttles and Dampers: Controlling the Engine of Membrane Fusion

1997 • 107 citations

Interactions of N-stearoyl sphingomyelin with cholesterol and dipalmitoylphosphatidylcholine in bilayer membranes

1996 • 107 citations

Topology of sphingolipid galactosyltransferases in ER and Golgi: transbilayer movement of monohexosyl sphingolipids is required for higher glycosphingolipid biosynthesis.

1996 • 106 citations

Phenotypes of sphingolipid-dependent strains of Saccharomyces cerevisiae

1992 • 105 citations

Transport of sphingomyelin to the cell surface is inhibited by brefeldin A and in mitosis, where C6-NBD-sphingomyelin is translocated across the plasma membrane by a multidrug transporter activity

1997 • 105 citations

Localization of globoside and forssman glycolipids on erythrocyte membranes

1983 • 104 citations

Plasticity in epithelial polarity of renal intercalated cells: targeting of the H(+)-ATPase and band 3

1996 • 104 citations

Lactosylceramide is synthesized in the lumen of the Golgi apparatus

1994 • 103 citations

Conversion of diacylglycerol to phosphatidylcholine on the basolateral surface of epithelial (Madin-Darby canine kidney) cells. Evidence for the reverse action of a sphingomyelin synthase.

1994 • 102 citations

Purification of the Serine Palmitoyltransferase Complex Responsible for Sphingoid Base Synthesis by Using Affinity Peptide Chromatography Techniques

2000 • 102 citations

The affinity of cholesterol for phosphatidylcholine and sphingomyelin

1979 • 100 citations

Spontaneous lipid transfer between organized lipid assemblies

1992 • 100 citations

Changes in the spectral properties of a plasma membrane lipid analog during the first seconds of endocytosis in living cells

1997 • 98 citations

The Dually Acylated NH2-terminal Domain of Gi1α Is Sufficient to Target a Green Fluorescent Protein Reporter to Caveolin-enriched Plasma Membrane Domains

1999 • 96 citations

Correction of Enzymatic and Lysosomal Storage Defects in Fabry Mice by Adenovirus-Mediated Gene Transfer

1999 • 96 citations

Identification of Triton X-100 Insoluble Membrane Domains in the Yeast Saccharomyces cerevisiae

1996 • 96 citations

Organization of ganglioside synthesis in the Golgi apparatus

1999 • 96 citations

Biosynthesis of mannosylinositolphosphoceramide in Saccharomyces cerevisiae is dependent on genes controlling the flow of secretory vesicles from the endoplasmic reticulum to the Golgi.

1991 • 96 citations

Rat intestinal glycolipids

1976 • 96 citations

Increased protein kinase or decreased PP2A activity bypasses sphingoid base requirement in endocytosis

2000 • 95 citations

A mutant cytochrome b5 with a lengthened membrane anchor escapes from the endoplasmic reticulum and reaches the plasma membrane.

1996 • 95 citations

Isolation, characterization, and expression of cDNA clones that encode rat UDP‐galactose: Ceramide galactosyltransferase

1994 • 94 citations

Direct visualization of redistribution and capping of fluorescent gangliosides on lymphocytes.

1984 • 94 citations

E/M dips. Evidence for lipids regularly distributed into hexagonal super-lattices in pyrene-PC/DMPC binary mixtures at specific concentrations

1992 • 93 citations

The glycosylceramides of the nematodeCaenorhabditis elegans contain an unusual, branched‐chain sphingoid base

1995 • 93 citations

Membrane Organization at Low Cholesterol Concentrations: A Study Using 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-Labeled Cholesterol

1996 • 93 citations

Monolayer coupling in sphingomyelin bilayer systems

1978 • 92 citations

Isolation of Functional Golgi-derived Vesicles with a Possible Role in Retrograde Transport

1998 • 91 citations

Use of brefeldin A to define sites of glycosphingolipid synthesis: GA2/GM2/GD2 synthase is trans to the brefeldin A block.

1990 • 90 citations

Segregation of Glucosylceramide and Sphingomyelin Occurs in the Apical to Basolateral Transcytotic Route in HepG2 Cells

1997 • 90 citations

Scale formation in algae

1991 • 90 citations

Oligomerization and Topology of the Golgi Membrane Protein Glucosylceramide Synthase

1999 • 89 citations

Accumulation of protein‐bound epidermal glucosylceramides in β‐glucocerebrosidase deficient type 2 Gaucher mice

1999 • 88 citations

Effects of Membrane Thickness on the Molecular Dynamics and Enzymic Activity of Reconstituted Ca-ATPase

1994 • 87 citations

Sorting of sphingolipids in the endocytic pathway of HT29 cells.

1991 • 86 citations

Targeting of proteins to the Golgi apparatus

1998 • 86 citations

Effects of phosphatidylcholine fatty acyl chain length on calcium binding and other functions of the calcium-magnesium-ATPase

1993 • 86 citations

An isoform of the phosphatidylinositol-transfer protein transfers sphingomyelin and is associated with the Golgi system

1995 • 85 citations

Biosynthesis and localization of gangliosides in cultured cells

1982 • 85 citations

Molecular conformations of cerebrosides in bilayers determined by Raman spectroscopy

1980 • 84 citations

Evidence for Transbilayer, Tail-to-Tail Cholesterol Dimers in Dipalmitoylglycerophosphocholine Liposomes

1995 • 83 citations

Morphology of mammalian sperm membranes during differentiation, maturation, and capacitation

1990 • 83 citations

Cytoplasmic sequence required for basolateral targeting of LDL receptor in livers of transgenic mice

1992 • 82 citations

Visualization and quantification of glycolipid polarity dynamics in the plasma membrane of the mammalian spermatozoon

1994 • 82 citations

Traffic, polarity, and detergent solubility of a glycosylphosphatidylinositol-anchored protein after LDL-deprivation of MDCK cells.

1996 • 81 citations

Synthesis of monohydroxylated inositolphosphorylceramide (IPC-C) inSaccharomyces cerevisiae requires Scs7p, a protein with both a cytochrome b5-like domain and a hydroxylase/desaturase domain

1998 • 79 citations

The effect of undernutrition on the development of myelin in the rat central nervous system

1971 • 77 citations

Suppressor gene analysis reveals an essential role for sphingolipids in transport of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae

1997 • 77 citations

Viridiofungins, Novel Inhibitors of Sphingolipid Synthesis.

1997 • 77 citations

Subcellular distribution and biosynthesis of rat liver gangliosides

1987 • 74 citations

Perspectives on golgi apparatus form and function

1991 • 73 citations

Two Glycosphingolipid Sialyltransferases Are Localized in Different Sub-Golgi Compartments in Rat Liver

1989 • 73 citations

(Glyco)sphingolipids Are Sorted in Sub-Apical Compartments in HepG2 Cells: A Role for Non-Golgi–Related Intracellular Sites in the Polarized Distribution of (Glyco)sphingolipids

1998 • 73 citations

Interactions of gangliosides with phospholipids and glycosphingolipids in mixed monolayers

1978 • 73 citations

Monolayer characteristics and thermal behavior of natural and synthetic phosphatidylserines

1987 • 71 citations

Intracellular Distribution of a Biotin-labeled Ganglioside, GM1, by Immunoelectron Microscopy After Endocytosis in Fibroblasts

1999 • 70 citations

Sphingolipids: metabolism and cell signalling

1996 • 70 citations

Molecular Cloning, Characterization, and Expression of a Novel Human Neutral Sphingomyelinase

1999 • 70 citations

Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces

1999 • 69 citations

Calmodulin, a ganglioside-binding protein. Binding of gangliosides to calmodulin in the presence of calcium.

1992 • 69 citations

Cholesterol modulation of lipid intermixing in phospholipid and glycosphingolipid mixtures. Evaluation using fluorescent lipid probes and brominated lipid quenchers

1992 • 68 citations

Sphinganine 1-phosphate metabolism in cultured skin fibroblasts: evidence for the existence of a sphingosine phosphatase

1994 • 68 citations

Association of glycosphingolipids with intermediate filaments of mesenchymal, epithelial, glial, and muscle cells

1992 • 65 citations

Sphingomyelin and ceramide-phosphoethanolamine synthesis by microsomes and plasma membranes from rat liver and brain.

1987 • 65 citations

Ceramide and the eukaryotic stress response

1997 • 65 citations

Characterization of a new gene family developing pleiotropic phenotypes upon mutation inSaccharomyces cerevisiae

1995 • 64 citations

Inositol phosphoryl transferases from human pathogenic fungi

2000 • 64 citations

Transcriptional control of yeast plasma membrane H(+)-ATPase by glucose. Cloning and characterization of a new gene involved in this regulation.

1994 • 64 citations

CYTOSOLIC GANGLIOSIDES: OCCURRENCE IN CALF BRAIN AS GANGLIOSIDE‐PROTEIN COMPLEXES

1979 • 64 citations

Inhibition of serine palmitoyl-transferase activity by lipoxamycin.

1994 • 64 citations

Association of glycosphingolipids with intermediate filaments of human umbilical vein endothelial cells

1991 • 63 citations

Rapid turn-over of plasma membrane sphingomyelin and cholesterol in baby hamster kidney cells after exposure to sphingomyelinase

1990 • 63 citations

Sphingolipid transport in mitotic HeLa cells.

1992 • 62 citations

CHARACTERIZATION OF SULPHATIDE‐CONTAINING LIPOPROTEINS IN RAT BRAIN¹

1968 • 62 citations

Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants

1998 • 62 citations

Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. I. Distribution of the enzyme activity in microsomes, mitochondria, and golgi complex.

1980 • 61 citations

Isolation and structural analysis of three neutral glycosphingolipids from a mixed population of Caenorhabditis elegans (Nematoda: Rhabditida)

1997 • 60 citations

Evidence for association of glycosphingolipid with a colchicine-sensitive microtubule-like cytoskeletal structure of cultured cells

1981 • 60 citations

Aminopeptidase N is directly sorted to the apical domain in MDCK cells.

1990 • 59 citations

1 Gaucher's disease: past, present and future

1997 • 59 citations

Reconstitution of ATP- and Cytosol-dependent Transport of de Novo Synthesized Ceramide to the Site of Sphingomyelin Synthesis in Semi-intact Cells

2000 • 58 citations

An aureobasidin A resistance gene isolated from Aspergillus is a homolog of yeast AUR1, a gene responsible for inositol phosphorylceramide (IPC) synthase activity

1999 • 58 citations

Action of monensin, a monovalent cationophore, on cultured human fibroblasts: evidence that it induces high cellular accumulation of glucosyl- and lactosylceramide (gluco- and lactocerebroside)

1984 • 58 citations

Dehydroergosterol structural organization in aqueous medium and in a model system of membranes

1997 • 58 citations

Detailed structure of sphingomyelins and ceramides from different regions of bovine kidney with special reference to long-chain bases

1973 • 58 citations

Cloning and Expression of Glycolipid Transfer Protein from Bovine and Porcine Brain

2000 • 57 citations

Protein and lipid sorting from thetrans–Golgi network to secretory granules—recent developments

1998 • 57 citations

Detergent extraction of cholera toxin and gangliosides from cultured cells and isolated membranes

1982 • 57 citations

Mitochondrial and microsomal phospholipids of Morris hepatoma 7777.

1977 • 57 citations

8 Enzyme replacement therapy for Gaucher's disease

1997 • 56 citations

Anterograde transport through the Golgi complex: do Golgi tubules hold the key?

1995 • 55 citations

Sub-Golgi distribution in rat liver of CMP-NeuAc GM3- and CMP-NeuAc:GT1b alpha 2—-8sialyltransferases and comparison with the distribution of the other glycosyltransferase activities involved in ganglioside biosynthesis.

1990 • 55 citations

Sphingomyelin transport to the cell surface occurs independently of protein secretion in rat hepatocytes.

1993 • 53 citations

Effect of drugs and temperature on biosynthesis and transport of glycosphingolipids in cultured neurotumor cells

1984 • 53 citations

Insect glycolipids

1992 • 52 citations

Differential Thermal Analysis of Phospholipids

1965 • 52 citations

Phospholipid content of mitochondrial and microsomal membranes from Morris hepatomas of varying growth rates.

1979 • 51 citations

Phospholipid composition of mitochondria and microsomes from regenerating rat liver and hepatomas of different growth rate

1974 • 51 citations

Accessibility of Galactosyl Ceramides to Probe Reagents in Central Nervous System Myelin

1980 • 50 citations

Phospholipid asymmetry in renal brush-border membranes

1988 • 50 citations

Resynthesis of sphingomyelin from plasma-membrane phosphatidylcholine in BHK cells treated with Staphylococcus aureus sphingomyelinase

1988 • 49 citations

Intracellular lectins associated with N-linked glycoprotein traffic

1999 • 48 citations

Differential targeting of glucosylceramide and galactosylceramide analogues after synthesis but not during transcytosis in Madin-Darby canine kidney cells.

1995 • 47 citations

Rat intestinal glycolipids

1977 • 46 citations

Composition and physical properties of lipids from plasma membranes of dog kidney

1985 • 46 citations

Ceramide excluded from cell-free vesicular lipid transfer from endoplasmic reticulum to Golgi apparatus. Evidence for lipid sorting

1993 • 45 citations

Topography of cerebroside sulfotransferase in Golgi-enriched vesicles from rat brain.

1983 • 45 citations

Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated

1998 • 45 citations

The envelope of vaccinia virus reveals an unusual phospholipid in Golgi complex membranes

1996 • 44 citations

The isolation and analysis of the luminal plasma membrane of calf urinary bladder epithelium

1979 • 44 citations

Fractionation of Primary Cultured Cerebellar Neurons: Distribution of Sialyltransferases Involved in Ganglioside Biosynthesis

1992 • 44 citations

Heterogeneous Distribution of the Unusual Phospholipid Semilysobisphosphatidic Acid through the Golgi Complex

1997 • 43 citations

Phospholipid metabolism of herpesvirus-infected and uninfected rabbit kidney cells

1971 • 43 citations

Identification of detergent-resistant plasma membrane microdomains in dictyostelium: enrichment of signal transduction proteins.

1997 • 42 citations

A Neutral Magnesium-dependent Sphingomyelinase Isoform Associated with Intracellular Membranes and Reversibly Inhibited by Reactive Oxygen Species

2000 • 42 citations

Formation of a cytosolic ganglioside-protein complex following administration of photoreactive ganglioside GM1 to human fibroblasts in culture

1990 • 41 citations

Fluidity and composition of brush border and basolateral membranes from rat kidney

1984 • 40 citations

ER/Golgi Intermediates Acquire Golgi Enzymes by Brefeldin a–Sensitive Retrograde Transport in Vitro

1999 • 38 citations

Soluble Gangliosides in Cultured Neurotumor Cells

1983 • 36 citations

Accessibility of phospholipids in the chromaffin granule membrane

1978 • 35 citations

Sphingomyelin synthase is absent from endosomes

1997 • 35 citations

Ceramide Accumulation Uncovers a Cycling Pathway for the cis-Golgi Network Marker, Infectious Bronchitis Virus M Protein

1997 • 34 citations

Isolation and characterization of plasma membranes from friend erythroleukaemic cells. A study with sphingomyelinase C

1983 • 33 citations

Asymmetric distribution of gangliosides in rat renal brush-border and basolateral membranes

1988 • 33 citations

Sphingolipid synthesis and membrane formation byPlasmodium

1996 • 33 citations

Outer Membrane Monolayer Domains from Two-Dimensional Surface Scanning Resistance Measurements

2000 • 33 citations

Detection of protein mediated glycosphingolipid clustering by the use of resonance energy transfer between fluorescent labelled lipids. A method established by applying the system ganglioside GM1 and cholera toxin B subunit

1992 • 33 citations

An apparent association between glycosylphosphatidylinositol-anchored proteins and a sphingolipid in Tetrahymena mimbres

1997 • 31 citations

Internalization and Sorting of Plasma Membrane Sphingolipid Analogues in Differentiating Oligodendrocytes

1999 • 30 citations

Studies on the Asymmetric Arrangement of Membrane-Lipid-Enveloped Virions as a Model System

1975 • 29 citations

Reply to Kolesnick and Hannun, and Perry and Hannun

1999 • 29 citations

Characterization of a Sphingomyelinase Activity inSaccharomyces cerevisiae

1997 • 29 citations

Biochemical characterization of the golgi complex of mammalian cells

1974 • 28 citations

Cytosolic gangliosides of rat brain: Their fractionation into protein‐bound complexes of different ganglioside compositions

1984 • 27 citations

Ultrastructure, polarité et reproduction de l'appareil de Golgi.

1957 • 27 citations

Chapter 4 Sphingomyelin: metabolism, chemical synthesis, chemical and physical properties

1982 • 26 citations

Separation and Characterization of Hematosides with Different Sialic Acids and Ceramides from Rat Small Intestine. Different Composition of Epithelial Cells versus Non-Epithelial Tissue and of Duodenum versus Jejunum-Ileum1

1981 • 26 citations

Characterization of rat kidney proximal tubule brush border membrane-associated phosphatidylinositol phosphodiesterase

1983 • 26 citations

A Sphingomyelin Transfer Protein in Rat Tumors and Fetal Liver

1982 • 25 citations

Brefeldin A induced inhibition of de novo globo- and neolacto-series glycolipid core chain biosynthesis in human cells. Evidence for an effect on beta 1–>4galactosyltransferase activity.

1992 • 25 citations

Ganglioside-binding proteins in skeletal and cardiac muscle

1991 • 24 citations

Effects of Brefeldin A on Synthesis and Intracellular Transport of Ganglioside GT3 by Chick Embryo Retina Cells

1995 • 23 citations

Influence of monovalent cation transport on anabolism of glycosphingolipids in cultured human fibroblasts

1985 • 22 citations

Asymmetry of the lipid-bilayer of Sindbis virus

1976 • 20 citations

Interleaflet clear space is reduced in the membrane of COP I and COP II-coated buds/vesicles.

1996 • 18 citations

Apical and basal Forssman antigen in MDCK II cells: a morphological and quantitative study.

1991 • 16 citations

Phytosphingosine is a characteristic component of the glycolipids in the vertebrate intestine

1987 • 14 citations

Assays for Transmembrane Movement of Sphingolipids

2000 • 13 citations

Expression of glycosphingolipids in serum-free primary cultures of mouse kidney cells: male-female differences and androgen sensitivity

1994 • 10 citations

Reevaluating the effect of Brefeldin A (BFA) on ganglioside synthesis: the location of GM2 synthase cannot be deduced from the inhibition of GM2 synthesis by BFA

1999 • 9 citations

Getting Stuck in the Golgi

2000 • 9 citations

Gangliosides GM1 and GD1b are not polarized in mature hippocampal neurons

1999 • 7 citations