Distribution of a Glycosylphosphatidylinositol-anchored Protein at the Apical Surface of MDCK Cells Examined at a Resolution of <100 Å Using Imaging Fluorescence Resonance Energy Transfer

Functional rafts in cell membranes

1997 • 9,471 citations

Ionic channels of excitable membranes

1985 • 7,199 citations

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

2013 • 2,950 citations

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1992 • 2,905 citations

Lipid sorting in epithelial cells

1988 • 1,354 citations

Resonance Energy Transfer: Methods and Applications

1994 • 1,245 citations

Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

1993 • 961 citations

Fluorescence resonance energy transfer

1995 • 878 citations

5′-Nucleotidase: molecular structure and functional aspects

1992 • 864 citations

Cyanine dye labeling reagents: Sulfoindocyanine succinimidyl esters

1993 • 851 citations

GPI-Anchored Cell-Surface Molecules Complexed to Protein Tyrosine Kinases

1991 • 848 citations

Caveolae, DIGs, and the dynamics of sphingolipid—cholesterol microdomains

1997 • 783 citations

Regulated internalization of caveolae.

1994 • 760 citations

The orientational freedom of molecular probes. The orientation factor in intramolecular energy transfer

1979 • 744 citations

A detergent-free method for purifying caveolae membrane from tissue culture cells.

1995 • 732 citations

Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior.

1994 • 688 citations

Fluorescence ratio imaging of cyclic AMP in single cells

1991 • 686 citations

On the Origin of Sphingolipid/Cholesterol-Rich Detergent-Insoluble Cell Membranes: Physiological Concentrations of Cholesterol and Sphingolipid Induce Formation of a Detergent-Insoluble, Liquid-Ordered Lipid Phase in Model Membranes

1997 • 661 citations

Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis

1994 • 646 citations

Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons

1993 • 549 citations

Polarized sorting in epithelia

1990 • 544 citations

The glycosyl-phosphatidylinositol anchor of membrane proteins

1989 • 520 citations

[13] Fluorescence resonance energy transfer

1995 • 513 citations

Sequestration of GPI-Anchored Proteins in Caveolae Triggered by Cross-Linking

1994 • 505 citations

Separation of Caveolae from Associated Microdomains of GPI-Anchored Proteins

1995 • 481 citations

A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells.

1989 • 478 citations

Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae.

1994 • 449 citations

The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway.

1990 • 444 citations

Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation.

1995 • 432 citations

Surface density determination in membranes by fluorescence energy transfer

1978 • 422 citations

An analytic solution to the Förster energy transfer problem in two dimensions

1979 • 418 citations

Mechanism of Membrane Anchoring Affects Polarized Expression of Two Proteins in MDCK Cells

1989 • 377 citations

Role of GTP Hydrolysis in Fission of Caveolae Directly from Plasma Membranes

1996 • 370 citations

Compartmentalized Activation of the High Affinity Immunoglobulin E Receptor within Membrane Domains

1997 • 353 citations

Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin.

1995 • 318 citations

Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment.

1995 • 294 citations

Imaging the intracellular trafficking and state of the AB5 quaternary structure of cholera toxin.

1996 • 286 citations

Fluorescence imaging spectroscopy and microscopy

1997 • 284 citations

Cyanine dye labeling reagents—carboxymethylindocyanine succinimidyl esters

1990 • 252 citations

Lipid microdomains in cell surface membranes

1997 • 245 citations

The dimeric nature of the gramicidin A transmembrane channel: Conductance and fluorescence energy transfer studies of hybrid channels

1977 • 237 citations

Glycophospholipid membrane anchoring provides clues to the mechanism of protein sorting in polarized epithelial cells

1990 • 233 citations

Interaction of hemoglobin with red blood cell membranes as shown by a fluorescent chromophore

1977 • 232 citations

Luminescence Digital Imaging Microscopy

1989 • 214 citations

Calculation on fluorescence resonance energy transfer on surfaces

1980 • 194 citations

Actin-containing matrix associated with the plasma membrane of murine tumour and lymphoid cells

1981 • 191 citations

Endocytosis of GPI-linked membrane folate receptor-alpha.

1996 • 188 citations

Physical association of complement receptor type 3 and urokinase-type plasminogen activator receptor in neutrophil membranes.

1994 • 187 citations

Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia.

1997 • 175 citations

Microspectroscopic imaging tracks the intracellular processing of a signal transduction protein: fluorescent-labeled protein kinase C beta I.

1996 • 167 citations

Differential Regulation and Function of CD73, a Glycosyl-Phosphatidylinositol–linked 70-kD Adhesion Molecule, on Lymphocytes and Endothelial Cells

1997 • 157 citations

Glycophorin A Helical Transmembrane Domains Dimerize in Phospholipid Bilayers: A Resonance Energy Transfer Study

1994 • 136 citations

Primary structure of rat liver 5'-nucleotidase deduced from the cDNA. Presence of the COOH-terminal hydrophobic domain for possible post-translational modification by glycophospholipid.

1990 • 134 citations

Urokinase-type plasminogen activator receptor reversibly dissociates from complement receptor type 3 (alpha M beta 2' CD11b/CD18) during neutrophil polarization.

1996 • 134 citations

Fluorescence lifetime imaging microscopy (flimscopy). Methodology development and application to studies of endosome fusion in single cells

1993 • 128 citations

Fluorescence energy transfer in two dimensions. A numeric solution for random and nonrandom distributions

1982 • 128 citations

GPI-anchored proteins, glycosphingolipids, and sphingomyelin are sequestered to caveolae only after crosslinking.

1996 • 121 citations

Apical targeting in polarized epithelial cells: There's more afloat than rafts

1997 • 118 citations

Structural studies on the membrane-bound immunoglobulin E-receptor complex. 1. Characterization of large plasma membrane vesicles from rat basophilic leukemia cells and insertion of amphipathic fluorescent probes

1983 • 113 citations

Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells.

1993 • 113 citations

FRET Microscopy: Digital Imaging of Fluorescence Resonance Energy Transfer. Application in Cell Biology

1989 • 113 citations

Resonance energy transfer microscopy: observations of membrane-bound fluorescent probes in model membranes and in living cells.

1986 • 105 citations

FRET for studying intracellular signalling

1993 • 101 citations

Characterization of proteins in detergent-resistant membrane complexes from Madin-Darby canine kidney epithelial cells

1995 • 98 citations

Chapter 8 Resonance Energy Transfer Microscopy

1989 • 96 citations

Chapter 11 Cytomegalovirus Plasmid Vectors for Permanent Lines of Polarized Epithelial Cells

1994 • 90 citations

Structural hierarchy in the clustering of HLA class I molecules in the plasma membrane of human lymphoblastoid cells.

1995 • 87 citations

New trends in photobiology

1992 • 85 citations

Traffic, polarity, and detergent solubility of a glycosylphosphatidylinositol-anchored protein after LDL-deprivation of MDCK cells.

1996 • 81 citations

Triton X-100-resistant membrane complexes from cultured kidney epithelial cells contain the Src family protein tyrosine kinase p62yes.

1994 • 80 citations

Guilty by insolubility - does a protein's detergent insolubility reflect a caveolar location?

1995 • 78 citations

Clustering of GPI-Anchored Folate Receptor Independent of Both Cross-Linking and Association with Caveolin

1997 • 69 citations

T Cell Signalling Through CD73

1997 • 65 citations

Guilt by insolubility - does a protein's detergent insolubility reflect a caveolar location?

1995 • 63 citations

Structural studies on the membrane-bound immunoglobulin E (IgE)-receptor complex. 2. Mapping of distances between sites on IgE and the membrane surface

1983 • 60 citations

[21] Energy transfer methods for detecting molecular clusters on cell surfaces

1997 • 60 citations

Mapping of adherens junction components using microscopic resonance energy transfer imaging

1995 • 58 citations

Fluorescence resonance energy transfer on single living cells. Application to binding of monovalent haptens to cell-bound immunoglobulin E

1991 • 54 citations

Rat liver dipeptidylpeptidase IV contains competing apical and basolateral targeting information.

1992 • 50 citations

Proximity relationships between the type I receptor for Fc_εe (Fc_εeRI) and the mast cell function‐associated antigen (MAFA) studied by donor photobleaching fluorescence resonance energy transfer microscopy

1996 • 49 citations

Theory for establishing proximity relations in biological membranes by excitation energy transfer measurements

1994 • 48 citations

Distribution of type I Fc epsilon-receptors on the surface of mast cells probed by fluorescence resonance energy transfer

1993 • 48 citations

Imaging Fluorescence Resonance Energy Transfer as Probe of Membrane Organization and Molecular Associations of GPI-Anchored Proteins

2003 • 47 citations

Aggregation state of melittin in lipid vesicle membranes

1991 • 46 citations

One antigen, one gold? A quantitative analysis of immunogold labeling of plasma membrane 5'-nucleotidase in frozen thin sections.

1987 • 41 citations

Determination of the fractal dimension of membrane protein aggregates using fluorescence energy transfer

1989 • 35 citations

A monoclonal antibody inhibiting rat liver 5′‐nucleotidase

1981 • 33 citations

Calculation of resonance energy transfer in crowded biological membranes

1995 • 33 citations

Imaging the Spatial Distribution of Membrane Receptors during Neutrophil Phagocytosis

1994 • 15 citations

[19] In situ resonance energy transfer microscopy: Monitoring membrane fusion in living cells

1993 • 9 citations