Targeting of protein ERGIC-53 to the ER/ERGIC/cis-Golgi recycling pathway.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1989 • 3,067 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1986 • 1,100 citations

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

1990 • 918 citations

[71] Use of eukaryotic expression technology in the functional analysis of cloned genes

1987 • 834 citations

Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.

1994 • 815 citations

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

1994 • 793 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family

1985 • 669 citations

How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum.

1994 • 617 citations

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs

1994 • 574 citations

Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum

1989 • 499 citations

Identification, by a monoclonal antibody, of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus.

1988 • 488 citations

Retrieval of transmembrane proteins to the endoplasmic reticulum.

1993 • 414 citations

Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa.

1993 • 413 citations

Folding of VSV G Protein: Sequential Interaction with BiP and Calnexin

1994 • 316 citations

Distribution of the intermediate elements operating in ER to Golgi transport

1991 • 315 citations

Sequences within and adjacent to the transmembrane segment of alpha-2,6-sialyltransferase specify Golgi retention.

1991 • 296 citations

Kin recognition between medial Golgi enzymes in HeLa cells.

1994 • 278 citations

Subcellular organization of glycosylation in mammalian cells

1987 • 271 citations

Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast.

1994 • 265 citations

A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin.

1991 • 257 citations

Identification of an intermediate compartment involved in protein transport from endoplasmic reticulum to Golgi apparatus.

1990 • 252 citations

Retention and retrieval in the endoplasmic reticulum and the Golgi apparatus

1994 • 243 citations

The membrane spanning domain of beta-1,4-galactosyltransferase specifies trans Golgi localization.

1991 • 237 citations

Kin recognition

1993 • 223 citations

Cytochemical localization of terminal N-acetyl-D-galactosamine residues in cellular compartments of intestinal goblet cells: implications for the topology of O-glycosylation.

1984 • 217 citations

Beta-COP localizes mainly to the cis-Golgi side in exocrine pancreas.

1993 • 190 citations

A Golgi retention signal in a membrane-spanning domain of coronavirus E1 protein.

1991 • 185 citations

Sorting of membrane proteins in the secretory pathway

1993 • 171 citations

ERGIC-53, a membrane protein of the ER-Golgi intermediate compartment, carries an ER retention motif.

1993 • 167 citations

Golgi retention of a trans-Golgi membrane protein, galactosyltransferase, requires cysteine and histidine residues within the membrane-anchoring domain.

1992 • 162 citations

Oligomerization of a membrane protein correlates with its retention in the Golgi complex

1993 • 154 citations

The signal for Golgi retention of bovine beta 1,4-galactosyltransferase is in the transmembrane domain.

1992 • 148 citations

Characterization of a novel 63 kDa membrane protein : Implications for the organization of the ER-to-Golgi pathway

1993 • 137 citations

Subcellular localization of the UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-mediated O-glycosylation reaction in the submaxillary gland.

1994 • 136 citations

The signal anchor and stem regions of the beta-galactoside alpha 2,6-sialyltransferase may each act to localize the enzyme to the Golgi apparatus.

1992 • 134 citations

The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network.

1994 • 134 citations

The 17-residue transmembrane domain of beta-galactoside alpha 2,6-sialyltransferase is sufficient for Golgi retention

1992 • 126 citations

ERGIC-53, a Membrane Protein of the Endoplasmic Reticulum-Golgi Intermediate Compartment, Is Identical to MR60, an Intracellular Mannose-specific Lectin of Myelomonocytic Cells

1995 • 121 citations

The isolated ER-Golgi intermediate compartment exhibits properties that are different from ER and cis-Golgi.

1991 • 116 citations

About turn for the COPs?

1994 • 114 citations

Involvement of the CD4 molecule in a post‐activation event on T cell proliferation

1987 • 102 citations

Beta 1,4-galactosyltransferase: a short NH2-terminal fragment that includes the cytoplasmic and transmembrane domain is sufficient for Golgi retention.

1992 • 100 citations

The transmembrane and flanking sequences of beta 1,2-N-acetylglucosaminyltransferase I specify medial-Golgi localization.

1992 • 92 citations

The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast.

1994 • 89 citations

The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system.

1992 • 89 citations

The transmembrane domain of N-glucosaminyltransferase I contains a Golgi retention signal.

1992 • 84 citations

Retention of a cis Golgi protein requires polar residues on one face of a predicted alpha-helix in the transmembrane domain.

1993 • 70 citations

A novel endocytosis signal related to the KKXX ER-retrieval signal.

1995 • 69 citations

Retention of p63 in an ER-Golgi intermediate compartment depends on the presence of all three of its domains and on its ability to form oligomers.

1994 • 63 citations

A dual role for COOH-terminal lysine residues in pre-Golgi retention and endocytosis of ERGIC-53.

1994 • 35 citations