Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Glycosphingolipids in Cellular Interaction, Differentiation, and Oncogenesis

1981 • 1,650 citations

Glycosyltransferases

1989 • 904 citations

GOLGI FRACTIONS PREPARED FROM RAT LIVER HOMOGENATES

1973 • 449 citations

Dissection of the Golgi complex. I. Monensin inhibits the transport of viral membrane proteins from medial to trans Golgi cisternae in baby hamster kidney cells infected with Semliki Forest virus.

1983 • 430 citations

Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus.

1990 • 369 citations

Isolation of rat hepatocyte plasma membranes. I. Presence of the three major domains.

1983 • 306 citations

Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane.

1985 • 297 citations

Mechanism of galactosylation in the Golgi apparatus. A Chinese hamster ovary cell mutant deficient in translocation of UDP-galactose across Golgi vesicle membranes.

1986 • 213 citations

Compartmentation of asparagine-linked oligosaccharide processing in the Golgi apparatus.

1983 • 203 citations

A simple and fast method for the isolation of basolateral plasma membranes from rat small-intestinal epithelial cells

1980 • 185 citations

Metabolism and intracellular transport of glycosphingolipids

1990 • 178 citations

Distribution of terminal glycosyltransferases in hepatic Golgi fractions.

1980 • 166 citations

AN IMPROVED CELL FRACTIONATION PROCEDURE FOR THE PREPARATION OF RAT LIVER MEMBRANE-BOUND RIBOSOMES

1973 • 152 citations

Dissection of the Golgi complex. II. Density separation of specific Golgi functions in virally infected cells treated with monensin.

1983 • 144 citations

Topology of glucosylceramide synthesis in Golgi membranes from porcine submaxillary glands

1986 • 143 citations

The lysosomal localization of sphingolipid hydrolases

1968 • 122 citations

Lipid traffic in eukaryotic cells: mechanisms for intracelluar transport and organelle-specific enrichment of lipids

1990 • 114 citations

Modulation of Ganglioside Biosynthesis in Primary Cultured Neurons

1989 • 111 citations

[26] Lysogangliosides: Synthesis and use in preparing labeled gangliosides

1987 • 108 citations

Galactose transfer to endogenous acceptors within Golgi fractions of rat liver.

1982 • 105 citations

Free Sphingosine Formation from Endogenous Substrates by a Liver Plasma Membrane System with a Divalent Cation Dependence and a Neutral pH Optimum

1989 • 102 citations

Topography of glycosylation reactions in the rough endoplasmic reticulum membrane.

1986 • 99 citations

Biosynthesis and modification of Golgi mannosidase II in HeLa and 3T3 cells.

1985 • 94 citations

The subcellular localization of neutral sphingomyelinase in rat liver.

1979 • 92 citations

Transmembrane movements of lipids

1990 • 86 citations

Translocation of UDP-N-acetylglucosamine into vesicles derived from rat liver rough endoplasmic reticulum and Golgi apparatus.

1985 • 81 citations

Isolation of a functional vesicular intermediate that mediates ER to Golgi transport in yeast.

1990 • 76 citations

Tunicamycin inhibits ganglioside biosynthesis in rat liver Golgi apparatus by blocking sugar nucleotide transport across the membrane vesicles.

1983 • 75 citations

Two Glycosphingolipid Sialyltransferases Are Localized in Different Sub-Golgi Compartments in Rat Liver

1989 • 73 citations

Glycolipid and glycoprotein transport through the Golgi complex are similar biochemically and kinetically. Reconstitution of glycolipid transport in a cell free system.

1990 • 65 citations

Passage of serum-destined proteins through the Golgi apparatus of rat liver. An examination of heavy and light Golgi fractions.

1978 • 64 citations

Action of monensin, a monovalent cationophore, on cultured human fibroblasts: evidence that it induces high cellular accumulation of glucosyl- and lactosylceramide (gluco- and lactocerebroside)

1984 • 58 citations

Glycolipid transfer protein and intracellular traffic of glucosylceramide

1990 • 58 citations

UDPglucose-ceramide glucosyltransferase from porcine submaxillary glands is associated with the Golgi apparatus

1985 • 58 citations

Sub-Golgi distribution in rat liver of CMP-NeuAc GM3- and CMP-NeuAc:GT1b alpha 2—-8sialyltransferases and comparison with the distribution of the other glycosyltransferase activities involved in ganglioside biosynthesis.

1990 • 55 citations

Inhibition of the action of pyrophosphatase and phosphatase on sugar nucleotides.

1981 • 49 citations

Glucosylceramide synthase of mouse kidney: Further characterization with an improved assay method

1990 • 35 citations

Chemical and enzymic degradations of nucleoside mono- and diphosphate sugars

1979 • 32 citations

Enzymatic glucosylation of dolichol monophosphate and transfer of glucose from isolated dolichyl‐<scp>D</scp>‐glucosyl phosphate to ceramides by BHK‐21 cell microsemes

1984 • 14 citations

Solubilization of UDPglucose-ceramide glucosyltransferase from the Golgi apparatus

1990 • 13 citations

Subcellular biosynthesis and transport of gangliosides formed from exogenous lactosylceramide in rat liver

1990 • 12 citations

Evidence for coupling between transport of UDP-glucose and its synthesis by membrane-bound pyrophosphorylase in golgi apparatus of cat liver

1984 • 10 citations