(Glyco)sphingolipids Are Sorted in Sub-Apical Compartments in HepG2 Cells: A Role for Non-Golgi–Related Intracellular Sites in the Polarized Distribution of (Glyco)sphingolipids

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Functional rafts in cell membranes

1997 • 9,471 citations

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

2013 • 2,950 citations

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1992 • 2,905 citations

Lipid sorting in epithelial cells

1988 • 1,354 citations

Cell Surface Polarity in Epithelia

1985 • 880 citations

MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine

1996 • 863 citations

Membrane transport in the endocytic pathway

1995 • 644 citations

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro.

1989 • 588 citations

Polarized sorting in epithelia

1990 • 544 citations

Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes.

1994 • 384 citations

Biogenesis of the rat hepatocyte plasma membrane in vivo: comparison of the pathways taken by apical and basolateral proteins using subcellular fractionation.

1987 • 383 citations

Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver

1984 • 359 citations

Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA

1986 • 313 citations

Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane.

1985 • 297 citations

Sorting of an apical plasma membrane glycoprotein occurs before it reaches the cell surface in cultured epithelial cells.

1984 • 247 citations

Meeting of the apical and basolateral endocytic pathways of the Madin-Darby canine kidney cell in late endosomes.

1989 • 226 citations

Novel pyridinium surfactants for efficient, nontoxic in vitro gene delivery

1997 • 203 citations

Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome

1994 • 186 citations

The response of the Golgi complex to microtubule alterations: the roles of metabolic energy and membrane traffic in Golgi complex organization.

1989 • 185 citations

Endocytic pathways in polarized Caco-2 cells: identification of an endosomal compartment accessible from both apical and basolateral surfaces.

1990 • 169 citations

Differential microtubule requirements for transcytosis in MDCK cells.

1990 • 159 citations

Biogenesis of epithelial cell polarity: Intracellular sorting and vectorial exocytosis of an apical plasma membrane glycoprotein

1984 • 157 citations

Receptor-mediated binding and uptake of immunoglobulin a by human liver

1988 • 152 citations

Intracellular sorting and basolateral appearance of the G protein of vesicular stomatitis virus in Madin-Darby canine kidney cells.

1985 • 145 citations

Expression of macrophage-lymphocyte Fc receptors in Madin-Darby canine kidney cells: polarity and transcytosis differ for isoforms with or without coated pit localization domains.

1989 • 143 citations

Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization.

1993 • 142 citations

Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells

1997 • 141 citations

Rab17 Regulates Membrane Trafficking through Apical Recycling Endosomes in Polarized Epithelial Cells

1998 • 141 citations

Receptor-mediated vectorial transcytosis of epidermal growth factor by Madin-Darby canine kidney cells.

1987 • 138 citations

Transcellular transport of polymeric IgA in the rat hepatocyte: biochemical and morphological characterization of the transport pathway.

1985 • 134 citations

5'nucleotidase is sorted to the apical domain of hepatocytes via an indirect route [published erratum appears in J Cell Biol 1993 Nov;123(3):following 767]

1992 • 121 citations

Apical targeting in polarized epithelial cells: There's more afloat than rafts

1997 • 118 citations

Postendocytotic sorting of the ligand for the polymeric immunoglobulin receptor in Madin-Darby canine kidney cells.

1989 • 116 citations

Apical Plasma Membrane Proteins and Endolyn-78 Travel through a Subapical Compartment in Polarized WIF-B Hepatocytes

1998 • 111 citations

Microtubule perturbation retards both the direct and the indirect apical pathway but does not affect sorting of plasma membrane proteins in intestinal epithelial cells (Caco-2).

1990 • 108 citations

Generation of lipid polarity in intestinal epithelial (Caco-2) cells: sphingolipid synthesis in the Golgi complex and sorting before vesicular traffic to the plasma membrane.

1990 • 96 citations

Segregation of Glucosylceramide and Sphingomyelin Occurs in the Apical to Basolateral Transcytotic Route in HepG2 Cells

1997 • 90 citations

Sphingolipid Transport to the Apical Plasma Membrane Domain in Human Hepatoma Cells Is Controlled by PKC and PKA Activity: A Correlation with Cell Polarity in HepG2 Cells

1997 • 83 citations

The polymeric immunoglobulin receptor. A model protein to study transcytosis.

1991 • 77 citations

Newly synthesized hepatocyte plasma membrane proteins are transported in transcytotic vesicles in the bile duct-ligated rat

1993 • 75 citations

A facile synthesis of ceramides

1975 • 57 citations

Differential targeting of glucosylceramide and galactosylceramide analogues after synthesis but not during transcytosis in Madin-Darby canine kidney cells.

1995 • 47 citations

The transcytotic pathway of an apical plasma membrane protein (B10) in hepatocytes is similar to that of IgA and occurs via a tubular pericentriolar compartment

1996 • 47 citations

The Fate of Polymeric and Secretory Immunoglobulin A After Retrograde Infusion into the Common Bile Duct in Rats

1984 • 46 citations

Regulation of Protein Traffic in Polarized Epithelial Cells: The Polymeric Immunoglobulin Receptor Model

1995 • 45 citations

Recycling pathways of glucosylceramide in BHK cells: distinct involvement of early and late endosomes

1992 • 41 citations

Priority targeting of glycosyl-phosphatidylinositol-anchored proteins to the bile-canalicular (apical) plasma membrane of hepatocytes. Involvement of ‘late’ endosomes

1990 • 38 citations

Immunoadsorption of Hepatic Vesicles Carrying Newly Synthesized Dipeptidyl Peptidase IV and Polymeric IgA Receptor

1995 • 35 citations

Intracellular sites involved in the biogenesis of bile canaliculi in hepatic cells.

1994 • 33 citations

Hydrolysis of galactosylsphingosine and lactosylsphingosine by β-galactosidases in human brain and cultured fibroblasts

1987 • 12 citations

Plasma membrane domain localization and transcytosis of the glucagon-induced hepatic system A carrier

1992 • 12 citations