THE CAVEOLAE MEMBRANE SYSTEM

Functional rafts in cell membranes

1997 • 9,471 citations

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1992 • 2,905 citations

Caveolin, a protein component of caveolae membrane coats

1992 • 2,230 citations

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

1985 • 1,585 citations

Lipid sorting in epithelial cells

1988 • 1,354 citations

Phase equilibria of cholesterol/dipalmitoylphosphatidylcholine mixtures: deuterium nuclear magnetic resonance and differential scanning calorimetry

1990 • 1,100 citations

Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains

1996 • 1,006 citations

Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

1993 • 961 citations

Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation.

1989 • 920 citations

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease.

1994 • 912 citations

Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules.

1994 • 894 citations

VIP21/caveolin is a cholesterol-binding protein.

1995 • 892 citations

GPI-Anchored Cell-Surface Molecules Complexed to Protein Tyrosine Kinases

1991 • 848 citations

Acylation Targets Endothelial Nitric-oxide Synthase to Plasmalemmal Caveolae

1996 • 798 citations

CLATHRIN-COATED VESICLE FORMATION AND PROTEIN SORTING: An Integrated Process

1997 • 793 citations

THE FINE STRUCTURE OF THE GALL BLADDER EPITHELIUM OF THE MOUSE

1955 • 791 citations

Src Tyrosine Kinases, Gα Subunits, and H-Ras Share a Common Membrane-anchored Scaffolding Protein, Caveolin

1996 • 770 citations

Regulated internalization of caveolae.

1994 • 760 citations

Potocytosis: Sequestration and Transport of Small Molecules by Caveolae

1992 • 751 citations

The Adaptor Protein Shc Couples a Class of Integrins to the Control of Cell Cycle Progression

1996 • 739 citations

Molecular Cloning of Caveolin-3, a Novel Member of the Caveolin Gene Family Expressed Predominantly in Muscle

1996 • 737 citations

Regulation of Integrin Function by the Urokinase Receptor

1996 • 734 citations

A detergent-free method for purifying caveolae membrane from tissue culture cells.

1995 • 732 citations

Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells

1996 • 692 citations

Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior.

1994 • 688 citations

Selective solubilization of proteins and phospholipids from red blood cell membranes by nonionic detergents

1973 • 687 citations

Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling.

1996 • 677 citations

Endothelial Nitric Oxide Synthase Targeting to Caveolae

1996 • 670 citations

On the Origin of Sphingolipid/Cholesterol-Rich Detergent-Insoluble Cell Membranes: Physiological Concentrations of Cholesterol and Sphingolipid Induce Formation of a Detergent-Insoluble, Liquid-Ordered Lipid Phase in Model Membranes

1997 • 661 citations

Caveolae: where incoming and outgoing messengers meet.

1993 • 616 citations

Evidence for a Regulated Interaction between Heterotrimeric G Proteins and Caveolin

1995 • 612 citations

De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin.

1995 • 597 citations

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.

1996 • 566 citations

Flotillin and Epidermal Surface Antigen Define a New Family of Caveolae-associated Integral Membrane Proteins

1997 • 549 citations

Oligomeric structure of caveolin: implications for caveolae membrane organization.

1995 • 547 citations

VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles.

1992 • 544 citations

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform [published erratum appears in J Cell Biol 1995 Jul;130(2):501]

1995 • 541 citations

Permeability of muscle capillaries to small heme-peptides. Evidence for the existence of patent transendothelial channels.

1975 • 540 citations

Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate.

1990 • 533 citations

Endothelial Nitric Oxide Synthase Is Regulated by Tyrosine Phosphorylation and Interacts with Caveolin-1

1996 • 532 citations

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

1996 • 516 citations

STUDIES ON BLOOD CAPILLARIES

1968 • 506 citations

Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae.

1994 • 506 citations

Sequestration of GPI-Anchored Proteins in Caveolae Triggered by Cross-Linking

1994 • 505 citations

Reduction of caveolin and caveolae in oncogenically transformed cells.

1995 • 505 citations

A Role for Caveolin in Transport of Cholesterol from Endoplasmic Reticulum to Plasma Membrane

1996 • 496 citations

Separation of Caveolae from Associated Microdomains of GPI-Anchored Proteins

1995 • 481 citations

The concept of lipid domains in membranes.

1982 • 466 citations

VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro.

1995 • 465 citations

Caveolae and sorting in the trans-Golgi network of epithelial cells.

1993 • 461 citations

Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton.

1989 • 457 citations

Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae.

1994 • 449 citations

Localization of Epidermal Growth Factor-stimulated Ras/Raf-1 Interaction to Caveolae Membrane

1996 • 449 citations

Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts

1983 • 445 citations

The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway.

1990 • 444 citations

Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins

1982 • 428 citations

Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation.

1994 • 425 citations

Calcium pump of the plasma membrane is localized in caveolae.

1993 • 419 citations

Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles.

1994 • 413 citations

Organization of Glycosphingolipids in Bilayers and Plasma Membranes of Mammalian Cells

1985 • 395 citations

Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae.

1994 • 389 citations

Characterization of Detergent-insoluble Complexes Containing the Cellular Prion Protein and Its Scrapie Isoform

1997 • 388 citations

Bound simian virus 40 translocates to caveolin-enriched membrane domains, and its entry is inhibited by drugs that selectively disrupt caveolae.

1996 • 384 citations

Localization of Platelet-derived Growth Factor-stimulated Phosphorylation Cascade to Caveolae

1996 • 378 citations

Recombinant Expression of Caveolin-1 in Oncogenically Transformed Cells Abrogates Anchorage-independent Growth

1997 • 377 citations

Murine SR-BI, a High Density Lipoprotein Receptor That Mediates Selective Lipid Uptake, Is N-Glycosylated and Fatty Acylated and Colocalizes with Plasma Membrane Caveolae

1997 • 375 citations

Endothelial Caveolae Have the Molecular Transport Machinery for Vesicle Budding, Docking, and Fusion Including VAMP, NSF, SNAP, Annexins, and GTPases

1995 • 370 citations

Role of GTP Hydrolysis in Fission of Caveolae Directly from Plasma Membranes

1996 • 370 citations

Tyrosine Phosphorylation of a 22-kDa Protein Is Correlated with Transformation by Rous Sarcoma Virus

1989 • 363 citations

Caveolin Is Palmitoylated on Multiple Cysteine Residues

1995 • 356 citations

Localization and Turnover of Phosphatidylinositol 4,5-Bisphosphate in Caveolin-enriched Membrane Domains

1996 • 354 citations

Compartmentalized Production of Ceramide at the Cell Surface

1995 • 352 citations

Purification and characterization of smooth muscle cell caveolae.

1994 • 347 citations

Phosphorylation of Caveolin by Src Tyrosine Kinases

1996 • 347 citations

Apolipoprotein-mediated removal of cellular cholesterol and phospholipids

1996 • 346 citations

Membrane organization in G‐protein mechanisms

1994 • 345 citations

Caveolin-3 Associates with Developing T-tubules during Muscle Differentiation

1997 • 345 citations

Localization of inositol 1,4,5-trisphosphate receptor-like protein in plasmalemmal caveolae.

1992 • 345 citations

Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin.

1994 • 333 citations

Differential Activation of Mitogen-activated Protein Kinases by Nitric Oxide-related Species

1996 • 332 citations

Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin.

1995 • 318 citations

Interaction of cholesterol with various glycerophospholipids and sphingomyelin

1990 • 310 citations

Cholesterol-induced fluid-phase immiscibility in membranes.

1991 • 305 citations

Cholesterol and vesicular stomatitis virus G protein take separate routes from the endoplasmic reticulum to the plasma membrane.

1990 • 304 citations

The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases.

1992 • 300 citations

Signal transduction through decay-accelerating factor. Interaction of glycosyl-phosphatidylinositol anchor and protein tyrosine kinases p56lck and p59fyn 1.

1992 • 286 citations

Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles.

1988 • 285 citations

Cellular aspects of transcapillary exchange

1983 • 277 citations

A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits.

1994 • 276 citations

Dynamic Targeting of the Agonist-stimulated m2 Muscarinic Acetylcholine Receptor to Caveolae in Cardiac Myocytes

1997 • 275 citations

Organized Endothelial Cell Surface Signal Transduction in Caveolae Distinct from Glycosylphosphatidylinositol-anchored Protein Microdomains

1997 • 274 citations

Plasma membrane caveolae mediate the efflux of cellular free cholesterol

1995 • 273 citations

The vesiculo-vacuolar organelle (VVO): a distinct endothelial cell structure that provides a transcellular pathway for macromolecular extravasation

1996 • 266 citations

Transport of cholesterol from the endoplasmic reticulum to the plasma membrane.

1985 • 263 citations

Endocytosis of simian virus 40 into the endoplasmic reticulum.

1989 • 257 citations

Bradykinin Sequesters B2 Bradykinin Receptors and the Receptor-coupled Gα Subunits Gαq and Gαiin Caveolae in DDT1 MF-2 Smooth Muscle Cells

1997 • 256 citations

Chemoattractant-Regulated Mobilization of a Novel Intracellular Compartment in Human Neutrophils

1987 • 256 citations

Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway.

1987 • 254 citations

Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor.

1995 • 250 citations

Tyrosine Kinase Receptors Concentrated in Caveolae-like Domains from Neuronal Plasma Membrane

1997 • 248 citations

Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains.

1996 • 246 citations

Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps.

1995 • 243 citations

Palmitoylation of Endothelial Nitric Oxide Synthase Is Necessary for Optimal Stimulated Release of Nitric Oxide: Implications for Caveolae Localization

1996 • 243 citations

Major histocompatibility complex class I molecules mediate association of SV40 with caveolae.

1997 • 242 citations

Caveolin mRNA levels are up-regulated by free cholesterol and down-regulated by oxysterols in fibroblast monolayers

1997 • 241 citations

M‐caveolin, a muscle‐specific caveolin‐related protein

1996 • 238 citations

Myristoylation and Differential Palmitoylation of the HCK Protein-Tyrosine Kinases Govern Their Attachment to Membranes and Association with Caveolae

1995 • 237 citations

Lipid polarity and sorting in epithelial cells

1988 • 236 citations

Dual pathways of internalization of the cholecystokinin receptor.

1995 • 236 citations

Lowering the cholesterol content of MA104 cells inhibits receptor-mediated transport of folate.

1992 • 233 citations

COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

1997 • 232 citations

VIP36, a novel component of glycolipid rafts and exocytic carrier vesicles in epithelial cells.

1994 • 232 citations

Glycosylphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway.

1996 • 232 citations

The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles

1992 • 223 citations

Expression and Characterization of Recombinant Caveolin

1996 • 223 citations

Platelet-derived growth factor activates mitogen-activated protein kinase in isolated caveolae

1997 • 221 citations

Insulin stimulates the tyrosine phosphorylation of caveolin.

1995 • 215 citations

Specific release of membrane-bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol.

1997 • 213 citations

Ligand-induced protease receptor translocation into caveolae: a mechanism for regulating cell surface proteolysis of the tissue factor-dependent coagulation pathway.

1996 • 212 citations

Organization of G Proteins and Adenylyl Cyclase at the Plasma Membrane

1997 • 211 citations

Mitogenesis, cell migration, and loss of focal adhesions induced by tenascin-C interacting with its cell surface receptor, annexin II.

1996 • 208 citations

Oligomerization of VIP21‐caveolin in vitro is stabilized by long chain fatty acylation or cholesterol

1996 • 205 citations

Intracellular transport of cholesterol to the plasma membrane.

1982 • 203 citations

Both Sphingolipids and Cholesterol Participate in the Detergent Insolubility of Alkaline Phosphatase, a Glycosylphosphatidylinositol-anchored Protein, in Mammalian Membranes

1995 • 200 citations

Signal transduction in macrophages by glycosylphosphatidylinositols ofPlasmodium,Trypanosoma, andLeishmania: Activation of protein tyrosine kinases and protein kinase C by inositolglycan and diacylglycerol moieties

1997 • 198 citations

The tyrosine kinase connection: how GPI-anchored proteins activate T cells

1993 • 198 citations

Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae.

1993 • 197 citations

Caveolae: Static inpocketings of the plasma membrane, dynamic vesicles or plain artifact?

1988 • 197 citations

PERMEABILITY OF MUSCLE CAPILLARIES TO EXOGENOUS MYOGLOBIN

1973 • 196 citations

The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae.

1995 • 196 citations

Two related but distinct forms of the Mr 36,000 tyrosine kinase substrate (calpactin) that interact with phospholipid and actin in a Ca2+-dependent manner.

1986 • 196 citations

Immunoisolation and partial characterization of endothelial plasmalemmal vesicles (caveolae).

1997 • 195 citations

alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor.

1995 • 194 citations

The glycophosphatidylinositol-anchored Thy-1 molecule interacts with the p60fyn protein tyrosine kinase in T cells.

1992 • 191 citations

Endocytosis of GPI-linked membrane folate receptor-alpha.

1996 • 188 citations

Protein kinase C activators inhibit receptor-mediated potocytosis by preventing internalization of caveolae

1994 • 184 citations

A photo‐reactive derivative of ganglioside GM1 specifically cross‐links VIP21‐caveolin on the cell surface

1995 • 181 citations

Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia.

1997 • 175 citations

Hormonal regulation of caveolae internalization.

1995 • 170 citations

Detergent insolubility of alkaline phosphatase during biosynthetic transport and endocytosis. Role of cholesterol.

1993 • 169 citations

Association of p75 with Caveolin and Localization of Neurotrophin-induced Sphingomyelin Hydrolysis to Caveolae

1997 • 169 citations

Endocytosis of GPI-anchored proteins in human lymphocytes: role of glycolipid-based domains, actin cytoskeleton, and protein kinases.

1996 • 156 citations

Receptor‐mediated endocytosis of plasminogen activators and activator/inhibitor complexes

1994 • 148 citations

Lateral diffusion of membrane-spanning and glycosylphosphatidylinositol-linked proteins: toward establishing rules governing the lateral mobility of membrane proteins.

1991 • 146 citations

Morphological Changes Of The 3T3-L1 Fibroblast Plasma Membrane Upon Differentiation To The Adipocyte Form

1983 • 146 citations

Biochemical Characterization and Cytochemical Localization of a Catecholamine-Sensitive Adenylate Cyclase in Isolated Capillary Endothelium

1972 • 145 citations

Integrin alpha 7 as substrate for a glycosylphosphatidylinositol-anchored ADP-ribosyltransferase on the surface of skeletal muscle cells.

1993 • 143 citations

Endothelial plasmalemmal vesicles have a characteristic striped bipolar surface structure.

1985 • 140 citations

Caveolae, transmembrane signalling and cellular transformation

1995 • 139 citations

Exogenous glycosyl phosphatidylinositol-anchored CD59 associates with kinases in membrane clusters on U937 cells and becomes Ca(2+)-signaling competent.

1995 • 138 citations

Retargeting of cytosolic proteins to the plasma membrane by the Lck protein tyrosine kinase dual acylation motif

1997 • 136 citations

Endocytosis of glycophospholipid-anchored and transmembrane forms of CD4 by different endocytic pathways.

1992 • 129 citations

Thy-1 glycoprotein and src-like protein-tyrosine kinase p53/p56lyn are associated in large detergent-resistant complexes in rat basophilic leukemia cells.

1993 • 125 citations

Transfer of cholesterol from its site of synthesis to the plasma membrane.

1984 • 122 citations

The folate receptor works in tandem with a probenecid-sensitive carrier in MA104 cells in vitro.

1991 • 122 citations

GPI-anchored proteins, glycosphingolipids, and sphingomyelin are sequestered to caveolae only after crosslinking.

1996 • 121 citations

Cholesterol homeostasis. Modulation by amphiphiles.

1994 • 120 citations

Host signal transduction and endocytosis ofCampylobacter jejuni

1996 • 120 citations

Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells.

1993 • 113 citations

Noncovalent associations of T lymphocyte surface proteins

1996 • 111 citations

Surface expression of Fc gamma receptor III (CD16) on chemoattractant-stimulated neutrophils is determined by both surface shedding and translocation from intracellular storage compartments.

1992 • 108 citations

VIP17/MAL, a proteolipid in apical transport vesicles

1995 • 107 citations

Characterization of the Molecular Mode of Action of the Sulfonylurea, Glimepiride, at β-Cells

1996 • 107 citations

Transendothelial transport of serum albumin: a quantitative immunocytochemical study

1992 • 103 citations

The NADPH oxidase complex of phagocytic leukocytes: a biochemical and cytochemical view

1995 • 103 citations

Transcytosis in the continuous endothelium of the myocardial microvasculature is inhibited by N-ethylmaleimide.

1994 • 102 citations

Endothelin-induced Endocytosis of Cell Surface ET @! Receptors

1995 • 102 citations

Rings of membrane sterols surround the openings of vesicles and fenestrae, in capillary endothelium.

1983 • 100 citations

Association of Engrailed homeoproteins with vesicles presenting caveolae-like properties

1997 • 100 citations

Molecular Dissection of the Role of the Membrane Domain in the Regulated Degradation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase

1995 • 99 citations

Large, detergent‐resistant complexes containing murine antigens Thy‐1 and Ly‐6 and protein tyrosine kinase p56^lck

1993 • 99 citations

Intracellular Transport of Low Density Lipoprotein Derived Free Cholesterol Begins at Clathrin-Coated Pits and Terminates at Cell Surface Caveolae

1996 • 98 citations

Expression and Regulation of Endothelial Nitric Oxide Synthase

1997 • 97 citations

Purification and Characterization of a Novel Endopeptidase in Ragweed (Ambrosia artemisiifolia) Pollen

1996 • 94 citations

Cross‐linking of CD59 and of other glycosyl phosphatidylinositol‐anchored molecules on neutrophils triggers cell activation via tyrosine kinase

1993 • 94 citations

Each Caveola Contains Multiple Glycosyl-phosphatidylinositol-anchored Membrane Proteins

1992 • 91 citations

A novel intracellular compartment with unusual secretory properties in human neutrophils.

1991 • 89 citations

Identification, Sequence, and Expression of an Invertebrate Caveolin Gene Family from the Nematode Caenorhabditis elegans

1997 • 89 citations

Cholesterol-rich intracellular membranes: a precursor to the plasma membrane.

1985 • 88 citations

VIP21‐Caveolin, a protein of the trans‐Golgi network and caveolae

1994 • 88 citations

Physical Association with Ras Enhances Activation of Membrane-bound Raf (RafCAAX)

1997 • 88 citations

Clustered folate receptors deliver 5-methyltetrahydrofolate to cytoplasm of MA104 cells.

1996 • 81 citations

Transfer of exogenous glycosylphos-phatidylinositol (GPI)-linked molecules to plasma membranes

1996 • 79 citations

Cholesterol movement from plasma membrane to rough endoplasmic reticulum. Inhibition by progesterone.

1994 • 78 citations

Folate receptors targeted to clathrin-coated pits cannot regulate vitamin uptake.

1995 • 78 citations

The annexin II2p112 complex is the major protein component of the Triton X-100-insoluble low-density fraction prepared from MDCK cells in the presence of Ca2+

1994 • 76 citations

The glycosylphosphatidylinositol‐anchored CD59 protein stimulates both T cell receptor ζ/ZAP‐70‐dependent and ‐independent signaling pathways in T cells

1995 • 72 citations

Activation of Protein Phosphorylation by Oxidants in Vascular Endothelial Cells: Identification of Tyrosine Phosphorylation of Caveolin

1997 • 71 citations

Increased expression of complement decay-accelerating factor during activation of human neutrophils.

1987 • 70 citations

Insulin and α₂‐macroglobulin‐methylamine undergo endocytosis by different mechanisms in rat adipocytes: II. Comparison of intracellular events

1987 • 70 citations

Insulin second messengers

1997 • 69 citations

Isolation and partial characterization of the luminal plasmalemma of microvascular endothelium from rat lungs.

1992 • 69 citations

Nonidet P-40 extraction of lymphocyte plasma membrane. Characterization of the insoluble residue

1984 • 66 citations

Insulin and α₂‐macroglobulin‐methylamine undergo endocytosis by different mechanisms in rat adipocytes: I. Comparison of cell surface events

1987 • 64 citations

Migrating Vascular Smooth Muscle Cells Polarize Cell Surface Urokinase Receptors after Injury in Vitro

1995 • 63 citations

Characterization of the Molecular Mode of Action of the Sulfonylurea, Glimepiride, at Adipocytes

1996 • 62 citations

Caveolae can be alternative endocytotic structures in elicited macrophages.

1997 • 59 citations

The Cellular Isoform of the Prion Protein, PRPC, Is Associated with Caveolae in Mouse Neuroblastoma (N2a) Cells

1995 • 59 citations

Bacterial lipopolysaccharide binds to CD14 in low-density domains of the monocyte-macrophage plasma membrane.

1995 • 57 citations

Detergent extraction of cholera toxin and gangliosides from cultured cells and isolated membranes

1982 • 57 citations

The MAL proteolipid is a component of the detergent-insoluble membrane subdomains of human T-lymphocytes

1997 • 56 citations

Effect of thermotropic phase transitions of dipalmitoylphosphatidylcholine on the formation of mixed micelles with Triton X-100

1974 • 53 citations

Regulation of the cytoplasmic accumulation of 5-methyltetrahydrofolate in MA104 cells is independent of folate receptor regulation.

1989 • 53 citations

The Multiligand α₂‐Macroglobulin Receptor/Low Density Lipoprotein Receptor‐Related Protein (α₂MR/LRP)

1994 • 52 citations

Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes

1996 • 51 citations

Ultrastructural Evidence of Differential Solubility in Triton X-100 of Endothelial Vesicles and Plasma Membrane

1995 • 45 citations

Receptor-Mediated Endocytosis and Intracellular Processing of Insulin: Ultrastructural and Biochemical Evidence for Cell-Specific Heterogeneity and Distinction from Nonhormonal Ligands

1989 • 44 citations

Identification of detergent-resistant plasma membrane microdomains in dictyostelium: enrichment of signal transduction proteins.

1997 • 42 citations

Caveolin and MAL, Two Protein Components of Internal Detergent-Insoluble Membranes, Are in Distinct Lipid Microenvironments in MDCK Cells

1997 • 42 citations

Isolation of phosphooligosaccharide/phosphoinositol glycan from caveolae and cytosol of insulin-stimulated cells.

1995 • 38 citations

Inhibitors That Block Both the Internalization of Caveolae and the Return of Plasmalemmal Vesicles

1995 • 38 citations

Clustered distribution of human placental alkaline phosphatase on the surface of both placental and cancer cells. Electron microscopic observations using gold-labeled antibodies.

1985 • 35 citations

A Vacuolar-Type Proton ATPase Mediates Acidification of Plasmalemmal Vesicles during Potocytosis

1996 • 35 citations

Differential localization of alkaline phosphatase in barrier tissues of the frog and rat nervous systems: A cytochemical and biochemical study

1987 • 32 citations

Association of the GPI-Anchored Leukocyte Surface Glycoproteins with Ganglioside GM3

1994 • 27 citations

Association of endothelial tissue factor and thrombomodulin with caveolae [letter]

1996 • 26 citations

Localization of atrial natriuretic peptide in caveolae of in situ atrial myocytes.

1994 • 26 citations

Cytochemical demonstration of adenylate cyclase activity with cerium

1985 • 25 citations

Intracellular calcium translocation during contraction in vertebrate and invertebrate smooth muscles as studied by the pyroantimonate method

1982 • 25 citations

Ultrastructural Localization of Ca++-ATPases in Meissner's Corpuscle of the Mongolian Gerbil.

1992 • 25 citations

Ecto‐ATPases and 5′‐nucleotidases in the caveolae of smooth muscle. Enzyme‐histochemical evidence may indicate a role for caveolae in neurotransmission.

1994 • 24 citations

Role of glycosyl-phosphatidylinositol hydrolysis as a mitogenic signal for epidermal growth factor

1995 • 24 citations

Cytochemical localization of 5?-nucleotidase in the enteric ganglia and in smooth muscle cells of the guinea-pig

1985 • 23 citations

Cytochemical studies of myocardial adenylate cyclase after its activation and inhibition.

1984 • 21 citations

Electron microscopic histochemistry of ATPase and alkaline phosphatase activities in mouse digital corpuscles

1980 • 19 citations

Solubilization of glycosyl-phosphatidylinositol-anchored proteins in quiescent and stimulated neutrophils

1995 • 18 citations

The role of palmitoyl–protein thioesterase in the palmitoylation of endothelial nitric oxide synthase

1997 • 14 citations

Poststimulatory endocytosis, microvesicle repopulation and changes in smooth endoplasmic reticulum in nerve endings of the median eminence superfused in vitro

1984 • 14 citations

The Plasma Membrane ‘Skeleton’ of Tumor and Lymphoid Cells: A Role in Cell Lysis?

1985 • 14 citations

Monoclonal antibodies to different epitopes on a cell-surface enzyme, human placental alkaline phosphatase, effect different patterns of labeling with protein A-colloidal gold.

1987 • 9 citations

Cytochemical Localization of NAD(P)H Oxidase in the Myoepithelial Cells of Salivary and Other Exocrine Glands.

1995 • 3 citations