Topology of sphingolipid galactosyltransferases in ER and Golgi: transbilayer movement of monohexosyl sphingolipids is required for higher glycosphingolipid biosynthesis.

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Brefeldin A: insights into the control of membrane traffic and organelle structure.

1992 • 1,848 citations

Vesicles of variable sizes produced by a rapid extrusion procedure

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Galectins. Structure and function of a large family of animal lectins.

1994 • 1,487 citations

TOPOGRAPHY OF GLYCOSYLATION IN THE ROUGH ENDOPLASMIC RETICULUM AND GOLGI APPARATUS

1987 • 596 citations

Fluorescence assay for phospholipid membrane asymmetry

1991 • 484 citations

Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus.

1994 • 447 citations

Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells.

1987 • 443 citations

Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver.

1992 • 343 citations

Apical membrane aminopeptidase appears at site of cell-cell contact in cultured kidney epithelial cells.

1980 • 329 citations

Ganglioside metabolism. Enzymology, Topology, and regulation.

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Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions

1992 • 306 citations

Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver

1991 • 282 citations

Assembly of Phospholipids into Cellular Membranes: Biosynthesis, Transmembrane Movement and Intracellular Translocation

1988 • 267 citations

Translocation across golgi vesicle membranes: A CHO glycosylation mutant deficient in CMP-sialic acid transport

1984 • 266 citations

Preparation of the active isomer of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthetase

1987 • 254 citations

Retention and retrieval in the endoplasmic reticulum and the Golgi apparatus

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Synthesis of cerebroside by brain from uridine diphosphate galactose and ceramide containing hydroxy fatty acid

1969 • 231 citations

Isolation of wheat germ agglutinin-resistant clones of Chinese hamster ovary cells deficient in membrane sialic acid and galactose.

1977 • 223 citations

Mechanism of galactosylation in the Golgi apparatus. A Chinese hamster ovary cell mutant deficient in translocation of UDP-galactose across Golgi vesicle membranes.

1986 • 213 citations

Efficient fluorography of 3H and 14C on thin layers

1978 • 190 citations

Separation of gluco- and galactocerebrosides by means of borate thin-layer chromatography

1966 • 182 citations

The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver

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Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression.

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Extensive exchange of rat liver microsomal phospholipids

1977 • 163 citations

Bidirectional transbilayer movement of phospholipid analogs in human red blood cells. Evidence for an ATP-dependent and protein-mediated process.

1992 • 160 citations

Complementation between mutants of CHO cells resistant to a variety of plant lectins

1977 • 159 citations

Mannose 6-phosphate-independent membrane association of cathepsin D, glucocerebrosidase, and sphingolipid-activating protein in HepG2 cells.

1991 • 156 citations

Topology of glucosylceramide synthesis in Golgi membranes from porcine submaxillary glands

1986 • 143 citations

A polarized epithelial cell mutant deficient in translocation of UDP-galactose into the Golgi complex.

1988 • 136 citations

Protein-mediated phospholipid translocation in the endoplasmic reticulum with a low lipid specificity

1990 • 136 citations

Subcellular localization of sugar nucleotide synthetases.

1980 • 135 citations

Subcellular localization of Forssman glycolipid in epithelial MDCK cells by immuno-electronmicroscopy after freeze-substitution.

1991 • 134 citations

Chapter 4 Poration by α-Toxin and Streptolysin O: An Approach to Analyze Intracellular Processes

1989 • 126 citations

A series of fluorescent N-acylsphingosines: synthesis, physical properties, and studies in cultured cells

1988 • 124 citations

Two strains of the Madin-Darby canine kidney (MDCK) cell line have distinct glycosphingolipid compositions.

1986 • 122 citations

Phosphatidylcholine mobility in liver microsomal membranes

1978 • 122 citations

Transport of newly synthesized glucosylceramide to the plasma membrane by a non-Golgi pathway.

1994 • 112 citations

Lactosylceramide is synthesized in the lumen of the Golgi apparatus

1994 • 103 citations

Topography of glycosyltransferases involved in the initial glycosylations of gangliosides.

1991 • 98 citations

Reconstitution of a phospholipid flippase from rat liver microsomes

1987 • 96 citations

Isolation, characterization, and expression of cDNA clones that encode rat UDP‐galactose: Ceramide galactosyltransferase

1994 • 94 citations

The UDP‐Galactose:Ceramide Galactosyltransferase: Expression Pattern in Oligodendrocytes and Schwann Cells During Myelination and Substrate Preference for Hydroxyceramide

1995 • 92 citations

Differential effects of brefeldin A on transport of secretory and lysosomal proteins.

1993 • 83 citations

Translocation of UDP-N-acetylglucosamine into vesicles derived from rat liver rough endoplasmic reticulum and Golgi apparatus.

1985 • 81 citations

Localization of O-glycan initiation, sphingomyelin synthesis, and glucosylceramide synthesis in Vero cells with respect to the endoplasmic reticulum-Golgi intermediate compartment.

1994 • 79 citations

Tunicamycin inhibits ganglioside biosynthesis in rat liver Golgi apparatus by blocking sugar nucleotide transport across the membrane vesicles.

1983 • 75 citations

A non-exchangeable fluorescent phospholipid analog as a membrane traffic marker of the endocytic pathway.

1990 • 72 citations

Association of glycosphingolipids with intermediate filaments of mesenchymal, epithelial, glial, and muscle cells

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Sphingolipid trafficking — sorted out?

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Sorting of newly synthesized galactosphingolipids to the two surface domains of epithelial cells.

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Glycolipid transfer protein and intracellular traffic of glucosylceramide

1990 • 58 citations

Regulated Galactolipid Synthesis and Cell Surface Expression in Schwann Cell Line D6P2T

1987 • 53 citations

[7] Measurement of intactness of rat liver endoplasmic reticulum

1989 • 51 citations

Short chain ceramides as substrates for glucocerebroside synthetase. Differences between liver and brain enzymes

1979 • 50 citations

Application of 5-azido-UDP-glucose and 5-azido-UDP-glucuronic acid photoaffinity probes for the determination of the active site orientation of microsomal UDP-glucosyltransferases and UDP-glucuronosyltransferases.

1992 • 48 citations

Carrier-mediated transport of intact UDP-glucuronic acid into the lumen of endoplasmic-reticulum-derived vesicles from rat liver

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Topography of cerebroside sulfotransferase in Golgi-enriched vesicles from rat brain.

1983 • 45 citations

Glycosphingolipid Composition of a Renal Cell Line (MDCK) and Its Onabain-Resistant Mutant1

1986 • 32 citations

Net mass transfer of galactosylceramide facilatated by glycolipid transfer protein from pig brain: a monolayer study

1985 • 29 citations

Localization in the Golgi apparatus of rat liver UDP-Gal:glucosylceramide .beta.1.fwdarw.4galactosyltransferase

1991 • 29 citations

Subcellular Distribution of UDP‐Galactose:Ceramide Galactosyltransferase in Rat Brain Oligodendroglia

1988 • 22 citations

Transport of biosynthetic sphingolipids from Golgi to plasma membrane in HT29 cells: involvement of different carrier vesicle populations.

1994 • 20 citations

Evidence for Direct Binding of Intracellularly Distributed Ganglioside GM2 to Isolated Vimentin Intermediate Filaments in Normal and Tay-Sachs Disease Human Fibroblasts.

1994 • 19 citations

The glycosphingolipid composition of the human hepatoma cell line, Hep-G2

1989 • 17 citations

Effects of Brefeldin A on Galactosphingolipid Synthesis in an Immortalized Schwann Cell Line: Evidence for Different Intracellular Locations of Galactosylceramide Sulfotransferase and Ceramide Galactosyltransferase Activities

1995 • 14 citations