ENDOCYTOSIS AND MOLECULAR SORTING

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

Mechanisms of intracellular protein transport

1994 • 2,280 citations

Caveolin, a protein component of caveolae membrane coats

1992 • 2,230 citations

ACIDIFICATION OF THE ENDOCYTIC AND EXOCYTIC PATHWAYS

1986 • 1,977 citations

The Biogenesis of Lysosomes

1989 • 1,583 citations

Endocytosis and the recycling of plasma membrane.

1983 • 1,447 citations

COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum

1994 • 1,294 citations

Endocytosis

1977 • 1,275 citations

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.

1994 • 1,206 citations

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation.

1993 • 1,125 citations

STRUCTURE AND FUNCTION OF THE MANNOSE 6-PHOSPHATE/INSULINLIKE GROWTH FACTOR II RECEPTORS

1992 • 1,056 citations

Interaction of Tyrosine-Based Sorting Signals with Clathrin-Associated Proteins

1995 • 955 citations

Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation.

1989 • 920 citations

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease.

1994 • 912 citations

Phosphatidylinositol 3-Kinase Encoded by Yeast VPS 34 Gene Essential for Protein Sorting

1993 • 909 citations

ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity

1993 • 900 citations

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1988 • 846 citations

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1991 • 832 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

1995 • 816 citations

Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway

1993 • 808 citations

Ubiquitination of a Yeast Plasma Membrane Receptor Signals Its Ligand-Stimulated Endocytosis

1996 • 789 citations

Regulated internalization of caveolae.

1994 • 760 citations

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

1995 • 760 citations

Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic

1991 • 757 citations

Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

1992 • 741 citations

Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF

1992 • 736 citations

Phosphoinositides as Regulators in Membrane Traffic

1996 • 717 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

Mutations in human dynamin block an intermediate stage in coated vesicle formation

1993 • 702 citations

Receptor-mediated endocytosis: insights from the lipoprotein receptor system.

1979 • 701 citations

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

1994 • 676 citations

The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway

1992 • 648 citations

Membrane transport in the endocytic pathway

1995 • 644 citations

Membrane flow during pinocytosis. A stereologic analysis.

1976 • 639 citations

Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells.

1983 • 636 citations

Rab 7: an important regulator of late endocytic membrane traffic.

1995 • 625 citations

De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin.

1995 • 597 citations

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro.

1989 • 588 citations

Segregation of transferrin to a mildly acidic (pH 6.5) para-golgi compartment in the recycling pathway

1984 • 586 citations

Three-dimensional visualization of coated vesicle formation in fibroblasts.

1980 • 576 citations

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs

1994 • 574 citations

A presynaptic inositol-5-phosphatase

1996 • 573 citations

Actin-Binding Protein Requirement for Cortical Stability and Efficient Locomotion

1992 • 567 citations

Rab9 functions in transport between late endosomes and the trans Golgi network.

1993 • 556 citations

Caveolae and caveolins

1996 • 549 citations

Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis

1991 • 543 citations

Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process.

1993 • 516 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Sequestration of GPI-Anchored Proteins in Caveolae Triggered by Cross-Linking

1994 • 505 citations

Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes.

1983 • 495 citations

Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling

1994 • 483 citations

Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae

1991 • 465 citations

Cytoplasmic Domain Heterogeneity and Functions of IgG Fc Receptors in B Lymphocytes

1992 • 462 citations

Caveolae and sorting in the trans-Golgi network of epithelial cells.

1993 • 461 citations

Transepithelial Transport of Immunoglobulins

1994 • 457 citations

N-glycans as apical sorting signals in epithelial cells

1995 • 454 citations

Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body

1990 • 452 citations

A Regulatory Role for ARF6 in Receptor-Mediated Endocytosis

1995 • 451 citations

Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae.

1994 • 449 citations

Toxoplasma gondii : Fusion Competence of Parasitophorous Vacuoles in Fc Receptor-Transfected Fibroblasts

1990 • 446 citations

Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor

1991 • 444 citations

Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria

1993 • 443 citations

Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes

1994 • 442 citations

Disappearance and reformation of synaptic vesicle membrane upon transmitter release observed under reversible blockage of membrane retrieval

1989 • 442 citations

Mechamisms of cell polarity: sorting and transport in epithelial cells

1994 • 430 citations

Movement of internalized ligand–receptor complexes along a continuous endosomal reticulum

1990 • 428 citations

Isolation and characterization of the intracellular MHC class II compartment

1994 • 426 citations

Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture

1990 • 425 citations

Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation.

1994 • 425 citations

The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein

1993 • 422 citations

Vacuolar ATPase activity is required for endosomal carrier vesicle formation.

1994 • 418 citations

Endosomes

1983 • 416 citations

The synaptic vesicle cycle: a single vesicle budding step involving clathrin and dynamin.

1996 • 412 citations

GTPases: Multifunctional Molecular Switches Regulating Vesicular Traffic

1994 • 411 citations

Cytoplasmic dynein-dependent vesicular transport from early to late endosomes [published erratum appears in J Cell Biol 1994 Feb;124(3):397]

1993 • 408 citations

A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.

1996 • 408 citations

Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin.

1995 • 400 citations

Hypervariable C-termmal domain of rab proteins acts as a targeting signal

1991 • 394 citations

Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells

1992 • 393 citations

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42.

1995 • 386 citations

Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes.

1994 • 384 citations

Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action.

1990 • 384 citations

Biogenesis of the rat hepatocyte plasma membrane in vivo: comparison of the pathways taken by apical and basolateral proteins using subcellular fractionation.

1987 • 383 citations

end3 and end4: two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae.

1993 • 380 citations

Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomes

1991 • 378 citations

Two distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomes

1988 • 377 citations

A novel class of clathrin-coated vesicles budding from endosomes.

1996 • 369 citations

Basolateral sorting of LDL receptor in MDCK cells: The cytoplasmic domain contains two tyrosine-dependent targeting determinants

1992 • 366 citations

Receptors compete for adaptors found in plasma membrane coated pits.

1988 • 366 citations

Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments.

1995 • 365 citations

Signal transduction in the mammalian cell during bacterial attachment and entry

1993 • 364 citations

Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver

1984 • 359 citations

Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: Effects of brefeldin A and G protein activators

1992 • 358 citations

An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes.

1996 • 357 citations

Structural relationships between clathrin assembly proteins from the Golgi and the plasma membrane.

1988 • 356 citations

Adsorptive endocytosis of Semliki Forest virus

1980 • 354 citations

Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes.

1994 • 349 citations

Actin and fimbrin are required for the internalization step of endocytosis in yeast.

1993 • 346 citations

The role of clathrin, adaptors and dynamin in endocytosis

1994 • 343 citations

Rab4 and cellubrevin define different early endosome populations on the pathway of transferrin receptor recycling.

1996 • 338 citations

Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor.

1989 • 336 citations

Macropinosome maturation and fusion with tubular lysosomes in macrophages.

1993 • 332 citations

Intracellular routing of transferrin and transferrin receptors in epidermoid carcinoma A431 cells

1983 • 330 citations

Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor.

1979 • 325 citations

Storage and release of neurotransmitters

1993 • 324 citations

Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling.

1992 • 321 citations

A quantitative analysis of the endocytic pathway in baby hamster kidney cells.

1989 • 315 citations

Rab GTPases: master regulators of membrane trafficking

1994 • 315 citations

Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans

1995 • 310 citations

The endocytic activity of dendritic cells.

1995 • 308 citations

Biochemical dissection of AP-1 recruitment onto Golgi membranes.

1993 • 308 citations

Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant

1991 • 304 citations

The Interaction of Bacteria with Mammalian Cells

1992 • 304 citations

The role of n-glycans in the secretory pathway

1995 • 295 citations

Colocalization of synaptophysin with transferrin receptors: implications for synaptic vesicle biogenesis.

1991 • 293 citations

Cytoplasmic coat proteins involved in endosome function

1995 • 290 citations

The small GTP-binding protein rab4 is associated with early endosomes.

1991 • 286 citations

Receptor-directed focusing of lymphokine release by helper T cells

1988 • 284 citations

The emergence of clathrin-independent pinocytic pathways

1995 • 282 citations

How MHC Class II Molecules Acquire Peptide Cargo: Biosynthesis and Trafficking through the Endocytic Pathway

1995 • 280 citations

Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages.

1992 • 277 citations

Rab proteins and the road maps for intracellular transport

1993 • 276 citations

Transcytosis of albumin in capillary endothelium.

1987 • 269 citations

Role of Type I Myosins in Receptor-Mediated Endocytosis in Yeast

1996 • 263 citations

Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells.

1995 • 263 citations

The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast.

1994 • 260 citations

Signal transduction and invasion of epithelial cells by S. typhimurium

1993 • 260 citations

Interaction of Activated EGF Receptors with Coated Pit Adaptins

1993 • 259 citations

Fc receptor isoforms exhibit distinct abilities for coated pit localization as a result of cytoplasmic domain heterogeneity

1989 • 259 citations

Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence.

1993 • 258 citations

Proton-Translocating ATPases

1986 • 255 citations

Hormone receptor topology and dynamics: Morphological analysis using ferritin-labeled epidermal growth factor

1979 • 254 citations

Selective inhibition of transcytosis by brefeldin A in MDCK cells

1991 • 254 citations

A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells.

1994 • 253 citations

Possible pathways for lysosomal enzyme delivery.

1985 • 253 citations

Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane

1992 • 252 citations

Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes.

1984 • 250 citations

Glycosphingolipid-enriched, detergent-insoluble complexes in protein sorting in epithelial cells

1993 • 246 citations

The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation

1991 • 246 citations

Tyrosine phosphorylation of the gamma subunit of Fc gamma receptors, p72syk, and paxillin during Fc receptor-mediated phagocytosis in macrophages.

1994 • 244 citations

Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps.

1995 • 243 citations

Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells.

1994 • 242 citations

Sorting of mannose 6-phosphate receptors and lysosomal membrane proteins in endocytic vesicles.

1988 • 241 citations

A novel adaptor-related protein complex.

1996 • 241 citations

Polarized sorting of glypiated proteins in hippocampal neurons

1991 • 233 citations

VIP36, a novel component of glycolipid rafts and exocytic carrier vesicles in epithelial cells.

1994 • 232 citations

Synthetic lethality screen identifies a novel yeast myosin I gene (MYO5): myosin I proteins are required for polarization of the actin cytoskeleton.

1996 • 229 citations

HVEM tomography of the trans-Golgi network: structural insights and identification of a lace-like vesicle coat.

1994 • 229 citations

Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells.

1994 • 227 citations

Perturbation of the morphology of the trans-Golgi network following Brefeldin A treatment: redistribution of a TGN-specific integral membrane protein, TGN38.

1992 • 226 citations

The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the Golgi.

1992 • 225 citations

Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol

1993 • 218 citations

Exocytosis of pinocytosed fluid in cultured cells: kinetic evidence for rapid turnover and compartmentation.

1981 • 215 citations

Quantification of low density lipoprotein and transferrin endocytic sorting in HEp2 cells using confocal microscopy

1994 • 212 citations

The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells.

1996 • 211 citations

Plasma Membrane Synthesis in the Macrophage following Phagocytosis of Polystyrene Latex Particles

1972 • 208 citations

Tubular early endosomal networks in AtT20 and other cells.

1991 • 208 citations

THE REGULATION OF PINOCYTOSIS IN MOUSE MACROPHAGES

1967 • 208 citations

A His-Leu-Leu sequence near the carboxyl terminus of the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor is necessary for the lysosomal enzyme sorting function.

1992 • 205 citations

Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes.

1995 • 202 citations

A Test of Clathrin Function in Protein Secretion and Cell Growth

1985 • 202 citations

Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages.

1993 • 201 citations

The Two Mannose 6-Phosphate Receptors Transport Distinct Complements of Lysosomal Proteins

1995 • 201 citations

Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosis.

1995 • 198 citations

Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis.

1983 • 195 citations

Functional properties of multiple synaptotagmins in brain

1994 • 195 citations

Binding and internalization of microorganisms by integrin receptors

1994 • 194 citations

Molecular Cloning of a Human Genomic Region Containing the H Blood Group α(1,2)Fucosyltransferase Gene and Two H Locus-related DNA Restriction Fragments

1995 • 191 citations

Signal transduction of phagocytosis

1995 • 190 citations

Retrieval of TGN proteins from the cell surface requires endosomal acidification.

1994 • 189 citations

Endocytosis of GPI-linked membrane folate receptor-alpha.

1996 • 188 citations

Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis.

1993 • 188 citations

M-CSF-induced macropinocytosis increases solute endocytosis but not receptor-mediated endocytosis in mouse macrophages

1992 • 188 citations

Biogenesis of synaptic vesicle-like structures in a pheochromocytoma cell line PC-12.

1990 • 187 citations

Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome

1994 • 186 citations

THE IN VITRO DIFFERENTIATION OF MONONUCLEAR PHAGOCYTES

1966 • 186 citations

Plasmalemmal caveolae and GPI-anchored membrane proteins

1993 • 186 citations

The tyrosine kinase substrate eps15 is constitutively associated with the plasma membrane adaptor AP-2.

1995 • 183 citations

Internalization and rapid recycling of macrophage Fc receptors tagged with monovalent antireceptor antibody: possible role of a prelysosomal compartment.

1984 • 176 citations

The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP.

1995 • 175 citations

Ca(2+)-independent F-actin assembly and disassembly during Fc receptor-mediated phagocytosis in mouse macrophages.

1991 • 175 citations

Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins

1993 • 174 citations

Transport of vesicular stomatitis virus G protein to the cell surface is signal mediated in polarized and nonpolarized cells.

1996 • 171 citations

Endocytic pathways in polarized Caco-2 cells: identification of an endosomal compartment accessible from both apical and basolateral surfaces.

1990 • 169 citations

Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells.

1992 • 167 citations

Common signals control low density lipoprotein receptor sorting in endosomes and the Golgi complex of MDCK cells

1993 • 167 citations

A targeting signal in VAMP regulating transport to synaptic vesicles

1995 • 166 citations

The essential tyrosine of the internalization signal in lysosomal acid phosphatase is part of a β turn

1991 • 165 citations

Distribution of newly synthesized lysosomal enzymes in the endocytic pathway of normal rat kidney cells.

1991 • 164 citations

Two yeast mutants defective in endocytosis are defective in pheromone response

1986 • 164 citations

Regulation of clathrin assembly and trimerization defined using recombinant triskelion hubs

1995 • 163 citations

Deep-etch visualization of proteins involved in clathrin assembly.

1988 • 163 citations

Three-dimensional structure of endosomes in BHK-21 cells.

1986 • 162 citations

Ultrastructural localization of the mannose 6-phosphate receptor in rat liver.

1984 • 162 citations

Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I.

1994 • 160 citations

Differential microtubule requirements for transcytosis in MDCK cells.

1990 • 159 citations

The function of dynamin in endocytosis

1995 • 159 citations

Membranes of sorting organelles display lateral heterogeneity in receptor distribution.

1987 • 158 citations

Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature-sensitive acidification-defective mutants.

1989 • 153 citations

Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment.

1995 • 153 citations

Endocytosis and Lysosomal Targeting of Epidermal Growth Factor Receptors Are Mediated by Distinct Sequences Independent of the Tyrosine Kinase Domain

1995 • 151 citations

β-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein

1995 • 150 citations

Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization. Contrasting significance of tyrosine 992 in the native and truncated receptors.

1992 • 150 citations

Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast

1993 • 150 citations

Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles.

1995 • 150 citations

Selective and immediate effects of clathrin heavy chain mutations on Golgi membrane protein retention in Saccharomyces cerevisiae.

1992 • 147 citations

Sorting of endocytosed transferrin and asialoglycoprotein occurs immediately after internalization in HepG2 cells.

1987 • 147 citations

Targeting signals and subunit interactions in coated vesicle adaptor complexes.

1995 • 145 citations

Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts.

1994 • 145 citations

The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomes

1994 • 145 citations

Rapid endocytosis of interleukin 2 receptors when clathrin-coated pit endocytosis is inhibited

1994 • 144 citations

TGN38/41 recycles between the cell surface and the TGN: brefeldin A affects its rate of return to the TGN.

1993 • 143 citations

Fc receptor endocytosis is controlled by a cytoplasmic domain determinant that actively prevents coated pit localization.

1992 • 142 citations

The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits

1992 • 141 citations

THE REGULATION OF PINOCYTOSIS IN MOUSE MACROPHAGES

1966 • 141 citations

Endothelial plasmalemmal vesicles have a characteristic striped bipolar surface structure.

1985 • 140 citations

Clustered syk tyrosine kinase domains trigger phagocytosis.

1996 • 140 citations

Disruptions in Golgi structure and membrane traffic in a conditional lethal mammalian cell mutant are corrected by epsilon-COP.

1994 • 139 citations

Selective iodination and polypeptide composition of pinocytic vesicles.

1980 • 130 citations

The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack.

1995 • 129 citations

Clathrin heavy chain is required for pinocytosis, the presence of large vacuoles, and development in Dictyostelium.

1992 • 126 citations

Phosphoinositide 3-kinases and membrane traffic

1996 • 124 citations

Transferrin receptors promote the formation of clathrin lattices

1991 • 122 citations

Mannose 6-Phosphate Receptors and ADP-ribosylation Factors Cooperate for High Affinity Interaction of the AP-1 Golgi Assembly Proteins with Membranes

1996 • 121 citations

Partial purification and characterization of early and late endosomes from yeast. Identification of four novel proteins

1993 • 120 citations

Stoichiometric Interaction of the Epidermal Growth Factor Receptor with the Clathrin-associated Protein Complex AP-2

1995 • 119 citations

GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration.

1993 • 118 citations

Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells.

1995 • 116 citations

Phagosome-lysosome fusion. Characterization of intracellular membrane fusion in mouse macrophages.

1980 • 116 citations

Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages.

1990 • 112 citations

Distinct signals in the GLUT4 glucose transporter for internalization and for targeting to an insulin-responsive compartment.

1995 • 111 citations

A Leu-Leu sequence is essential for COOH-terminal targeting signal of GLUT4 glucose transporter in fibroblasts.

1994 • 110 citations

[24] Tightly regulated and inducible expression of dominant interfering dynamin mutant in stably transformed HeLa cells

1995 • 109 citations

The cytoplasmic tail of lysosomal acid phosphatase contains overlapping but distinct signals for basolateral sorting and rapid internalization in polarized MDCK cells.

1993 • 108 citations

Polarized sorting of the polymeric immunoglobulin receptor in the exocytotic and endocytotic pathways is controlled by the same amino acids.

1994 • 106 citations

In Vitro Assembly and Disassembly of Coatomer

1995 • 106 citations

Two threshold values of low pH block endocytosis at different stages.

1987 • 106 citations

Different Domains of the AP-1 Adaptor Complex Are Required for Golgi Membrane Binding and Clathrin Recruitment

1995 • 104 citations

Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors.

1993 • 104 citations

Adaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits.

1993 • 102 citations

Binding of AP-1 Golgi adaptors to membranes requires phosphorylated cytoplasmic domains of the mannose 6-phosphate/insulin-like growth factor II receptor.

1993 • 101 citations

Immunofluorescent localization of 100K coated vesicle proteins.

1986 • 99 citations

The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations.

1991 • 97 citations

Clathrin and coated vesicles.

1987 • 95 citations

Conservation and diversity in families of coated vesicle adaptins.

1990 • 94 citations

Clathrin-coated pits contain an integral membrane protein that binds the AP-2 subunit with high affinity.

1990 • 93 citations

Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins.

1993 • 93 citations

Targeting and mistargeting of plasma membrane adaptors in vitro.

1993 • 92 citations

shibire, a neurogenic mutant of Drosophila

1990 • 91 citations

Each Caveola Contains Multiple Glycosyl-phosphatidylinositol-anchored Membrane Proteins

1992 • 91 citations

Potocytosis of small molecules and ions by caveolae

1993 • 87 citations

Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial missorting of multiple lysosomal enzymes.

1993 • 86 citations

Phosphorylation of the cation-independent mannose 6-phosphate receptor is closely associated with its exit from the trans-Golgi network.

1993 • 85 citations

A distinct class of intracellular storage vesicles, identified by expression of the glucose transporter GLUT4.

1994 • 85 citations

Membrane protein trafficking through the common apical endosome compartment of polarized Caco-2 cells.

1995 • 83 citations

Reconstitution of clathrin-coated pit budding from plasma membranes.

1991 • 83 citations

Genetic and Biochemical Characterization of Clathrin-Deficient Saccharomyces cerevisiae

1987 • 82 citations

Yeast ypt51p and mammalian rab5: Counterparts with similar function in the early endocytic pathway

1995 • 80 citations

Intracellular transport of transferrin- and asialoorosomucoid-colloidal gold conjugates to lysosomes after receptor-mediated endocytosis.

1985 • 79 citations

The intracellular tyrosine kinase domain of the epidermal growth factor receptor undergoes a conformational change upon autophosphorylation.

1994 • 78 citations

Folate receptors targeted to clathrin-coated pits cannot regulate vitamin uptake.

1995 • 78 citations

Two rat homologs of clathrin-associated adaptor proteins

1994 • 77 citations

Vacuolar ATPase inactivation blocks recycling to the trans‐Golgi network from the plasma membrane

1994 • 75 citations

The appendage domain of the AP-2 subunit is not required for assembly or invagination of clathrin-coated pits.

1993 • 75 citations

Identification of the carboxy terminus as important for the isoform-specific subcellular targeting of glucose transporter proteins.

1993 • 75 citations

Yeast pheromone receptor endocytosis and hyperphosphorylation are independent of G protein-mediated signal transduction

1992 • 71 citations

Assembly and targeting of adaptin chimeras in transfected cells.

1993 • 71 citations

A novel endocytosis signal related to the KKXX ER-retrieval signal.

1995 • 69 citations

[22] Receptor-mediated endocytosis in semiintact cells

1992 • 65 citations

Cleavage of cellubrevin by tetanus toxin does not affect fusion of early endosomes.

1993 • 65 citations

Membrane proteins of the vacuolar system. III. Further studies on the composition and recycling of endocytic vacuole membrane in cultured macrophages

1983 • 65 citations

A monoclonal antibody to the heavy chain of clathrin.

1983 • 62 citations

TGN38 recycles basolaterally in polarized Madin-Darby canine kidney cells.

1994 • 56 citations

Genetic and biochemical characterization of clathrin-deficient Saccharomyces cerevisiae.

1987 • 50 citations

Molecular sorting in polarized and non-polarized cells: common problems, common solutions

1993 • 50 citations

Formation of synaptic vesicles

1994 • 49 citations

Isolation of three classes of conditional lethal Chinese hamster ovary cell mutants with temperature-dependent defects in low density lipoprotein receptor stability and intracellular membrane transport.

1994 • 49 citations

Polarized Distribution and Delivery of Plasma Membrane Proteins in Thyroid Follicular Epithelial Cells

1995 • 47 citations

Biogenesis of the apical endosome–lysosome complex during differentiation of absorptive epithelial cells in rat ileum

1991 • 47 citations

Dictyostelium discoideum mutants with conditional defects in phagocytosis.

1994 • 40 citations

The role of small GTP-binding proteins in leukocyte function

1994 • 39 citations

Mice sans synaptotagmin

1994 • 38 citations

Biochemical Heterogeneity and Phosphorylation of Coatomer Subunits

1996 • 38 citations

Interactions of bacteria with non-phagocytic cells

1994 • 38 citations

A Cytoplasmic Tyrosine Is Essential for the Basolateral Localization of Mutants of the Human Nerve Growth Factor Receptor in Madin- Darby Canine Kidney Cells

1995 • 37 citations

Epitope mapping of two isoforms of a trans Golgi network specific integral membrane protein TGN38/41

1992 • 36 citations

The tyrosine-containing internalization motif in the cytoplasmic domain of TGN38/41 lies within a nascent helix.

1994 • 35 citations

Cytolysins from intracellular pathogens

1994 • 35 citations

A dual role for COOH-terminal lysine residues in pre-Golgi retention and endocytosis of ERGIC-53.

1994 • 35 citations

Transfection of an Fc gamma receptor cDNA induces T cells to become phagocytic.

1994 • 34 citations

Endocytosis without clathrin A minireview

1991 • 33 citations

An electron microscopic study of TGN38/41 dynamics

1993 • 22 citations

Molecular Sorting of Membrane Proteins in Polarized and Nonpolarized Cells

1995 • 20 citations

Structure and Properties of the Coated Vesicle Proton Pump

1992 • 15 citations

Internalization of polypeptide growth factor receptors and the regulation of transcription

1994 • 14 citations

Processing of defined T-cell epitopes after phagocytosis of intact bacteria by macrophages.

1993 • 9 citations

Glut-4 and Vamp-2 Are Segregated From Early Endosomes in Insulin-Sensitive But Not in Non-Insulin Sensitive Cells

1995 • 1 citations