Coregulatory Proteins in Nuclear Hormone Receptor Action

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 • 3,285 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

1997 • 2,510 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1997 • 2,100 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

1995 • 2,036 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

1996 • 1,678 citations

Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*

1997 • 1,678 citations

AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer

1997 • 1,655 citations

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

1996 • 1,567 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

1991 • 1,501 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

The PPARα–leukotriene B4 pathway to inflammation control

1996 • 1,328 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase

1997 • 1,251 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

1997 • 1,218 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Effects of Tamoxifen on Bone Mineral Density in Postmenopausal Women with Breast Cancer

1992 • 1,139 citations

Identification of a nuclear receptor that is activated by farnesol metabolites

1995 • 1,134 citations

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

1996 • 1,095 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells.

1996 • 964 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Role of CBP/P300 in nuclear receptor signalling

1996 • 935 citations

Nuclear receptor coactivators and corepressors.

1996 • 917 citations

Transcriptional regulation

1991 • 893 citations

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

1997 • 856 citations

What's Up and Down with Histone Deacetylation and Transcription?

1997 • 831 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

1994 • 813 citations

Differential Recognition of Target Genes by Nuclear Receptor Monomers, Dimers, and Heterodimers*

1994 • 789 citations

Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.

1990 • 772 citations

Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

1995 • 756 citations

High-Mobility-Group Chromosomal Proteins: Architectural Components That Facilitate Chromatin Function

1996 • 752 citations

The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements

1993 • 745 citations

Steroid Hormone Receptors: Interaction with Deoxyribonucleic Acid and Transcription Factors*

1993 • 724 citations

Nuclear receptor coactivators

1997 • 720 citations

Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation

1992 • 719 citations

GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.

1996 • 702 citations

Differential Activation of Peroxisome Proliferator-activated Receptors by Eicosanoids

1995 • 700 citations

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

1992 • 684 citations

Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones

1997 • 649 citations

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.

1994 • 649 citations

Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription

1994 • 645 citations

Coactivator and Corepressor Regulation of the Agonist/Antagonist Activity of the Mixed Antiestrogen, 4-Hydroxytamoxifen

1997 • 640 citations

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

1996 • 627 citations

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

1995 • 627 citations

Solution Structure of the Glucocorticoid Receptor DNA-Binding Domain

1990 • 609 citations

The Effect of Postmenopausal Estrogen Therapy on Bone Density in Elderly Women

1993 • 587 citations

RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2

1997 • 585 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

1995 • 578 citations

GRIP1, a Transcriptional Coactivator for the AF-2 Transactivation Domain of Steroid, Thyroid, Retinoid, and Vitamin D Receptors

1997 • 572 citations

Structural determinants of nuclear receptor assembly on DNA direct repeats

1995 • 561 citations

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

1996 • 532 citations

Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomised breast cancer prevention trial

1994 • 531 citations

Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation

1996 • 525 citations

PAS is a dimerization domain common to Drosophila Period and several transcription factors

1993 • 515 citations

Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.

1995 • 502 citations

Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α

1996 • 492 citations

The Partial Agonist Activity of Antagonist-Occupied Steroid Receptors Is Controlled by a Novel Hinge Domain-Binding Coactivator L7/SPA and the Corepressors N-CoR or SMRT

1997 • 468 citations

Solution structure of the DMA-binding domain of the oestrogen receptor

1990 • 458 citations

The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.

1996 • 453 citations

Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.

1993 • 451 citations

Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains

1992 • 446 citations

SRY, like HMG1, recognizes sharp angles in DNA.

1992 • 439 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

1995 • 431 citations

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

1995 • 429 citations

The Steroid Receptor Coactivator-1 Contains Multiple Receptor Interacting and Activation Domains That Cooperatively Enhance the Activation Function 1 (AF1) and AF2 Domains of Steroid Receptors

1998 • 421 citations

Nuclear Receptor-Binding Sites of Coactivators Glucocorticoid Receptor Interacting Protein 1 (GRIP1) and Steroid Receptor Coactivator 1 (SRC-1): Multiple Motifs with Different Binding Specificities

1998 • 417 citations

CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.

1996 • 414 citations

Nuclear receptor coactivators and corepressors

1996 • 414 citations

Structure of the HMG box motif in the B-domain of HMG1.

1993 • 403 citations

Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

1994 • 402 citations

p300 is a component of an estrogen receptor coactivator complex.

1996 • 399 citations

Interaction of Steroid Hormone Receptors with the Transcription Initiation Complex

1996 • 399 citations

Modulation of gene expression by calreticulin binding to the glucocorticoid receptor

1994 • 389 citations

The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

1992 • 381 citations

Interaction of proteins with transcriptionally active estrogen receptors.

1994 • 379 citations

Inhibition of nuclear hormone receptor activity by calreticulin

1994 • 372 citations

Interaction between the Amino- and Carboxyl-terminal Regions of the Rat Androgen Receptor Modulates Transcriptional Activity and Is Influenced by Nuclear Receptor Coactivators

1997 • 370 citations

Targeting Chromatin Disruption: Transcription Regulators that Acetylate Histones

1996 • 369 citations

Distinct classes of transcriptional activating domains function by different mechanisms

1990 • 368 citations

Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation.

1992 • 363 citations

Steroid hormone receptors and their regulation by phosphorylation

1996 • 361 citations

Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).

1992 • 354 citations

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

1992 • 341 citations

High-Mobility Group Chromatin Proteins 1 and 2 Functionally Interact with Steroid Hormone Receptors To Enhance Their DNA Binding In Vitro and Transcriptional Activity in Mammalian Cells

1998 • 338 citations

Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor.

1990 • 333 citations

High mobility group protein-1 (HMG-1) is a unique activator of p53

1998 • 316 citations

Identification of two transactlvation domains in the mouse oestrogen receptor

1989 • 303 citations

Anatomy of the Steroid Receptor Zinc Finger Region

1992 • 299 citations

The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific

1989 • 299 citations

Structure of the Retinoid X Receptor α DNA Binding Domain: a Helix Required for Homodimeric DNA Binding

1993 • 296 citations

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions

1994 • 293 citations

The orphan nuclear receptor LXRα is positively and negatively regulated by distinct products of mevalonate metabolism

1997 • 282 citations

Peroxisome Proliferator-Activated Receptors and Retinoic Acid Receptors Differentially Control the Interactions of Retinoid X Receptor Heterodimers with Ligands, Coactivators, and Corepressors

1997 • 279 citations

Solution structure of a DNA-binding domain from HMG1

1993 • 275 citations

Steroid receptor induction of gene transcription: A two-step model

1997 • 269 citations

The Nuclear Corepressors NCoR and SMRT Are Key Regulators of Both Ligand- and 8-Bromo-Cyclic AMP-Dependent Transcriptional Activity of the Human Progesterone Receptor

1998 • 264 citations

Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors

1993 • 264 citations

Mouse Glucocorticoid Receptor Phosphorylation Status Influences Multiple Functions of the Receptor Protein

1997 • 263 citations

A signature for the HMG‐1 box DNA‐binding proteins

1993 • 258 citations

Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator.

1996 • 258 citations

TBP-TAF complexes: selectivity factors for eukaryotic transcription

1994 • 250 citations

Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain.

1993 • 249 citations

Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells

1995 • 230 citations

HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation.

1996 • 230 citations

High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.

1995 • 224 citations

Identification of Nuclear Factors that Enhance Binding of the Thyroid Hormone Receptor to a Thyroid Hormone Response Element

1989 • 219 citations

SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae.

1992 • 217 citations

AF-2 Activity and Recruitment of Steroid Receptor Coactivator 1 to the Estrogen Receptor Depend on a Lysine Residue Conserved in Nuclear Receptors

1997 • 214 citations

Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription.

1995 • 212 citations

Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens

1995 • 206 citations

Orphan nuclear receptors--the first eight years.

1996 • 206 citations

The DNA-Bending Protein HMG-1 Enhances Progesterone Receptor Binding to Its Target DNA Sequences

1994 • 200 citations

Adaptor-mediated Recruitment of RNA Polymerase II to a Signal-dependent Activator

1996 • 199 citations

Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3.

1990 • 197 citations

High-mobility-group 1 protein mediates DNA bending as determined by ring closures.

1993 • 193 citations

A nuclear factor that enhances binding of thyroid hormone receptors to thyroid hormone response elements.

1990 • 192 citations

Structural determinants of DNA-binding specificity by steroid receptors.

1995 • 190 citations

Architectural Transcription Factors

1994 • 187 citations

Two types of antiprogestins identified by their differential action in transcriptionally active extracts from T47D cells

1991 • 182 citations

Coactivator and Corepressor Regulation of the Agonist/Antagonist Activity of the Mixed Antiestrogen, 4-Hydroxytamoxifen

1997 • 167 citations

Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor.

1994 • 165 citations

Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome

1996 • 165 citations

Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator.

1996 • 164 citations

Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor.

1995 • 160 citations

Yeast RSP5 and Its Human Homolog hRPF1 Potentiate Hormone-Dependent Activation of Transcription by Human Progesterone and Glucocorticoid Receptors

1996 • 160 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor

1995 • 154 citations

Endocrine effects of adjuvant chemotherapy and long-term tamoxifen administration on node-positive patients with breast cancer.

1987 • 154 citations

Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.

1997 • 141 citations

Activation of the TFIID-TFIIA complex with HMG-2.

1995 • 139 citations

Ligand-induced Conformational Alterations of the Androgen Receptor Analyzed by Limited Trypsinization

1995 • 132 citations

RIP-140 Interacts with Multiple Nuclear Receptors by Means of Two Distinct Sites

1996 • 132 citations

Differential DNA-binding abilites of estrogen receptor occupied with two classes of antiestrogens: studies using human estrogen receptor overexpressed in mammalian cells

1991 • 128 citations

The Partial Agonist Activity of Antagonist-Occupied Steroid Receptors Is Controlled by a Novel Hinge Domain-Binding Coactivator L7/SPA and the Corepressors N-CoR or SMRT

1997 • 126 citations

Examination of the DNA-binding ability of estrogen receptor in whole cells: implications for hormone-independent transactivation and the actions of antiestrogens.

1992 • 125 citations

Endoplasmic Reticulum Form of Calreticulin Modulates Glucocorticoid-sensitive Gene Expression

1996 • 122 citations

Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions.

1994 • 121 citations

Effect of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo.

1995 • 119 citations

Hormone-induced progesterone receptor phosphorylation consists of sequential DNA-independent and DNA-dependent stages: analysis with zinc finger mutants and the progesterone antagonist ZK98299.

1992 • 119 citations

Effects of hormone and cellular modulators of protein phosphorylation on transcriptional activity, DNA binding, and phosphorylation of human progesterone receptors.

1992 • 117 citations

Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast.

1992 • 116 citations

Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro.

1996 • 113 citations

Circumvention of tamoxifen resistance by the pure anti‐estrogen ICI 182, 780

1993 • 111 citations

A 55-Kilodalton Accessory Factor Facilitates Vitamin D Receptor DNA Binding

1991 • 109 citations

The DNA-bending protein HMG-1 enhances progesterone receptor binding to its target DNA sequences.

1994 • 108 citations

Role of Acidic and Phosphorylated Residues in Gene Activation by the Glucocorticoid Receptor

1995 • 107 citations

Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain

1993 • 105 citations

The interaction of human estrogen receptor with DNA is modulated by receptor-associated proteins.

1994 • 103 citations

Structure and Function of Estrogen Receptors

1995 • 100 citations

Nuclear localisation of calreticulin in vivo is enhanced by its interaction with glucocorticoid receptors

1997 • 99 citations

A nuclear hormone receptor-associated protein that inhibits transactivation by the thyroid hormone and retinoic acid receptors.

1995 • 97 citations

Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure.

1996 • 97 citations

A nuclear protein essential for binding of rat 1,25-dihydroxyvitamin D3 receptor to its response elements.

1992 • 94 citations

Nuclear Receptor-Binding Sites of Coactivators Glucocorticoid Receptor Interacting Protein 1 (GRIP1) and Steroid Receptor Coactivator 1 (SRC-1): Multiple Motifs with Different Binding Specificities

1998 • 93 citations

A single-stranded DNA-binding protein promotes the binding of the purified oestrogen receptor to its responsive element

1990 • 93 citations

Steroid Hormone-Dependent Interaction of Human Progesterone Receptor with its Target Enhancer Element

1988 • 92 citations

Assessment of glucocorticoid receptor-heat shock protein 90 interactions in vivo during nucleocytoplasmic trafficking.

1996 • 88 citations

Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues.

1992 • 86 citations

Binding of the estrogen receptor DNA-binding domain to the estrogen response element induces DNA bending.

1992 • 85 citations

Estrogens in the prevention and treatment of postmenopausal osteoporosis: a review

1988 • 84 citations

Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor

1994 • 84 citations

Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.

1996 • 83 citations

Ligands induce conformational changes in the carboxyl-terminus of progesterone receptors which are detected by a site-directed antipeptide monoclonal antibody.

1992 • 81 citations

Structural determinants of DNA-binding specificity by steroid receptors

1995 • 78 citations

Identification of a group of Ser-Pro motif hormone-inducible phosphorylation sites in the human progesterone receptor.

1995 • 78 citations

Androgen and glucocorticoid receptors interact with insulin degrading enzyme.

1994 • 77 citations

Orphan nuclear receptors--the first eight years

1996 • 76 citations

Receptor accessory factor enhances specific DNA binding of androgen and glucocorticoid receptors

1993 • 76 citations

Human Progesterone Receptor Binding to Mouse Mammary Tumor Virus Deoxyribonucleic Acid: Dependence on Hormone and Nonreceptor Nuclear Factor(s)

1989 • 73 citations

3,5,3′-Triiodothyronine Receptor Auxiliary Protein (TRAP) Enhances Receptor Binding by Interactions within the Thyroid Hormone Response Element

1991 • 73 citations

Calreticulin inhibits vitamin D₃signal transduction

1995 • 72 citations

Kinetics of glucocorticoid receptor phosphorylation in intact cells. Evidence for hormone-induced hyperphosphorylation after activation and recycling of hyperphosphorylated receptors.

1993 • 71 citations

High-Mobility Group (HMG) Protein HMG-1 and TATA-Binding Protein-Associated Factor TAF_II30 Affect Estrogen Receptor-Mediated Transcriptional Activation

1997 • 70 citations

Mutational Analysis Identifies a New Functional Domain of the Thyroid Hormone Receptor

1990 • 70 citations

Effect of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo

1995 • 70 citations

Effects of high mobility group proteins 1 and 2 on initiation and elongation of specific transcription by RNA polymerase IIin vitro

1988 • 69 citations

47 Analysis of SPT Genes: A Genetic Approach toward Analysis of TFIID, Histones, and Other Transcription Factors of Yeast

1992 • 65 citations

Role of Phosphorylation on DNA Binding and Transcriptional Functions of Human Progesterone Receptors

1996 • 64 citations

Yeast hormone response element assays detect and characterize GRIP1 coactivator-dependent activation of transcription by thyroid and retinoid nuclear receptors

1997 • 62 citations

The interaction of human estrogen receptor with DNA is modulated by receptor-associated proteins

1994 • 60 citations

16 alpha-substituted analogs of the antiprogestin RU486 induce a unique conformation in the human progesterone receptor resulting in mixed agonist activity.

1996 • 59 citations

Thyroid hormone responsiveness in human growth hormone-related genes. Possible correlation with receptor-induced DNA conformational changes.

1992 • 58 citations

Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast

1992 • 57 citations

Identification of a Transactivation Function in the Progesterone Receptor That Interacts with the TAFII110 Subunit of the TFIID Complex

1995 • 57 citations

Inhibition of Retinoic Acid Receptor Function and Retinoic Acid-regulated Gene Expression in Mouse Melanoma Cells by Calreticulin

1996 • 56 citations

Effects of hormone and cellular modulators of protein phosphorylation on transcriptional activity, DNA binding, and phosphorylation of human progesterone receptors

1992 • 56 citations

In vivo evidence against the existence of antiprogestins disrupting receptor binding to DNA.

1993 • 55 citations

Two Types of Anti-progestins Have Distinct Effects on Site-specific Phosphorylation of Human Progesterone Receptor

1996 • 55 citations

Ligand-induced alteration of the protease sensitivity of retinoid X receptor alpha.

1994 • 55 citations

Interaction of two nonhistone proteins with the estradiol response element of the avian vitellogenin gene modulates the binding of estradiol-receptor complex.

1987 • 51 citations

Estrogen receptor-induced DNA bending: orientation of the bend and replacement of an estrogen response element with an intrinsic DNA bending sequence.

1995 • 50 citations

Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator

1996 • 50 citations

Mapping the Domains of the Interaction of the Vitamin D Receptor and Steroid Receptor Coactivator-1

1998 • 49 citations

DNA bending by retinoid X receptor-containing retinoid and thyroid hormone receptor complexes.

1993 • 46 citations

RIP 140 Enhances Nuclear Receptor-Dependent Transcriptionin Vivoin Yeast

1997 • 46 citations

Progesterone receptor-induced bending of its target DNA: distinct effects of the A and B receptor forms.

1996 • 44 citations

DNA allosterically modulates the steroid binding domain of the estrogen receptor.

1992 • 44 citations

Constitutive expression of calreticulin in osteoblasts inhibits mineralization.

1995 • 44 citations

Structural Studies of Mutant Glucocorticoid Receptor Transactivation Domains Establish a Link between Transactivation Activity in Vivo and α-Helix-Forming Potential in Vitro

1996 • 43 citations

Thyroid hormone receptor-induced bending of specific DNA sequences is modified by an accessory factor.

1993 • 43 citations

Analysis of the Functional Role of Steroid Receptor Coactivator-1 in Ligand-Induced Transactivation by Thyroid Hormone Receptor

1997 • 41 citations

Heat shock protein is tightly associated with the recombinant human glucocorticoid receptor:glucocorticoid response element complex.

1994 • 41 citations

Evidence That Heat Shock Protein-70 Associated with Progesterone Receptors Is not Involved in Receptor-DNA Binding

1991 • 41 citations

Phosphorylation of Ser211 in the Chicken Progesterone Receptor Modulates its Transcriptional Activity

1996 • 41 citations

The Structure of the HMG Box and Its Interaction with DNA

1995 • 39 citations

Nuclear accessory factors enhance the binding of progesterone receptor to specific target DNA

1994 • 37 citations

Assessment of glucocorticoid receptor-heat shock protein 90 interactions in vivo during nucleocytoplasmic trafficking

1996 • 37 citations

Conformational Changes of Human β1 Thyroid Hormone Receptor Induced by Binding of 3,3′,5-Triiodo-L-thyronine

1993 • 36 citations

Identification of a group of Ser-Pro motif hormone-inducible phosphorylation sites in the human progesterone receptor

1995 • 35 citations

Glucocorticoid receptor binding to calf thymus DNA. 1. Identification and characterization of a macromolecular factor involved in receptor-steroid complex binding to DNA

1990 • 31 citations

Purification and characterization of a protein from HeLa cells that binds with high affinity to the estrogen response element, GGTCAGCGTGACC

1989 • 29 citations

Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues

1992 • 28 citations

Modulation of the Retinoic Acid and Retinoid X Receptor Signaling Pathways in P19 Embryonal Carcinoma Cells by Calreticulin

1997 • 28 citations

Deoxyribonucleic acid-binding ability of androgen receptors in whole cells: implications for the actions of androgens and antiandrogens.

1996 • 28 citations

Ligands induce conformational changes in the carboxyl-terminus of progesterone receptors which are detected by a site-directed antipeptide monoclonal antibody

1992 • 28 citations

Long-term tamoxifen therapy: can an antagonist become an agonist?

1996 • 28 citations

Definition of the critical cellular components which distinguish between hormone and antihormone activated progesterone receptor

1995 • 28 citations

Heat shock protein is tightly associated with the recombinant human glucocorticoid receptor:glucocorticoid response element complex

1994 • 25 citations

Induction of a novel conformation in the progesterone receptor by ZK299 involves a defined region of the carboxyl-terminal tail.

1996 • 25 citations

High-Mobility Group (HMG) Protein HMG-1 and TATA-Binding Protein-Associated Factor TAFII30 Affect Estrogen Receptor-Mediated Transcriptional Activation

1997 • 22 citations

Analysis of the Functional Role of Steroid Receptor Coactivator-1 in Ligand-Induced Transactivation by Thyroid Hormone Receptor

1997 • 22 citations

Calreticulin modulates the in vitro DNA binding but not the in vivo transcriptional activation by peroxisome proliferator-activated receptor/retinoid X receptor heterodimers

1995 • 21 citations

Molecular biology of steroid and nuclear hormone receptors

1999 • 21 citations

Progesterone receptor-induced bending of its target DNA: distinct effects of the A and B receptor forms

1996 • 21 citations

Estrogen receptor-induced DNA bending: orientation of the bend and replacement of an estrogen response element with an intrinsic DNA bending sequence

1995 • 19 citations

Mapping the Domains of the Interaction of the Vitamin D Receptor and Steroid Receptor Coactivator-1

1997 • 18 citations

Induction of a novel conformation in the progesterone receptor by ZK299 involves a defined region of the carboxyl-terminal tail

1996 • 17 citations

RIP 140 Enhances Nuclear Receptor-Dependent Transcription in Vivo in Yeast

1997 • 17 citations

Structure and Function of the Steroid and Nuclear Receptor Ligand Binding Domain

1998 • 17 citations

The Antagonists RU486 and ZK98299 Stimulate Progesterone Receptor Binding to Deoxyribonucleic Acid in Vitro and in Vivo, but Have Distinct Effects on Receptor Conformation

1998 • 16 citations

Nuclear extracts enhance the interaction of fusion proteins containing the DNA-binding domain of the androgen and glucocorticoid receptor with androgen and glucocorticoid response elements

1994 • 16 citations

Factor-assisted DNA binding as a possible general mechanism for steroid receptors. Functional heterogeneity among activated receptor-steroid complexes

1994 • 15 citations

Calreticulin inhibits glucocorticoid- but not cAMP-sensitive expression of tyrosine aminotransferase gene in cultured McA-RH7777 hepatocytes.

1997 • 12 citations

Long-term tamoxifen therapy: can an antagonist become an agonist?

1996 • 11 citations

Deoxyribonucleic acid-binding ability of androgen receptors in whole cells: implications for the actions of androgens and antiandrogens

1996 • 7 citations

Identification of a protein from rat liver cytosol that enhances activation of the glucocorticoid receptor

1988 • 5 citations

Remembering the dawn of the nuclear age

1995 • 2 citations

Deleted Work

1955 • 0 citations