High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

1990 • 1,630 citations

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

1986 • 1,150 citations

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

1994 • 930 citations

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

1994 • 813 citations

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

1988 • 750 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

1992 • 684 citations

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

1988 • 670 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

The High Mobility Group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene

1992 • 632 citations

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

1991 • 627 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

Specific Recognition of Cruciform DNA by Nuclear Protein HMG1

1989 • 596 citations

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

1994 • 506 citations

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1988 • 494 citations

Structural features of the HMG chromosomal proteins and their genes

1990 • 474 citations

Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations.

1992 • 461 citations

Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements

1993 • 440 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein

1988 • 399 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures.

1993 • 327 citations

Repressor structure and the mechanism of positive control

1983 • 324 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

Human and Drosophila Homeodomain Proteins That Enhance the DNA-Binding Activity of Serum Response Factor

1992 • 314 citations

HTLV-I Tax Protein Stimulation of DNA Binding of bZIP Proteins by Enhancing Dimerization

1993 • 312 citations

The POU domain is a bipartite DNA-binding structure

1988 • 304 citations

Cloning of a Lymphoid-Specific cDNA Encoding a Protein Binding the Regulatory Octamer DNA Motif

1988 • 304 citations

Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences

1986 • 298 citations

POU domain transcription factors

1993 • 278 citations

A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors

1992 • 272 citations

The DNA binding specificity of the bipartite POU domain and its subdomains.

1992 • 268 citations

DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1.

1991 • 265 citations

The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.

1993 • 258 citations

A signature for the HMG‐1 box DNA‐binding proteins

1993 • 258 citations

The intracellular distribution and function of the high mobility group chromosomal proteins

1985 • 241 citations

Short-Range DNA Looping by the Xenopus HMG-Box Transcription Factor, xUBF

1994 • 216 citations

The DNA-Bending Protein HMG-1 Enhances Progesterone Receptor Binding to Its Target DNA Sequences

1994 • 200 citations

Two regulatory elements for immunoglobulin kappa light chain gene expression.

1984 • 197 citations

The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein.

1994 • 174 citations

Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB).

1993 • 161 citations

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

1993 • 161 citations

Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells.

1990 • 146 citations

Multiple Oct2 isoforms are generated by alternative splicing

1991 • 141 citations

The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription.

1990 • 139 citations

A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain.

1992 • 134 citations

High mobility group proteins 1 and 2 function as general class II transcription factors

1990 • 129 citations

High mobility group proteins 1 and 2 stimulate transcription in vitro by RNA polymerases II and III.

1986 • 128 citations

Cell-type preference of immunoglobulin kappa and lambda gene promoters.

1985 • 118 citations

Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters.

1990 • 117 citations

Recognition of the surface of a homeo domain protein.

1992 • 115 citations

Complex pattern of immunoglobulin mu gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificities.

1991 • 99 citations

High mobility group proteins 1 and 2 stimulate binding of a specific transcription factor to the adenovirus major late promoter

1988 • 89 citations

The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP

1994 • 88 citations

The effect of a lambda repressor mutation on the activation of transcription initiation from the lambda PRM promoter

1983 • 83 citations

Stimulation of RNA Polymerase II Elongation by Chromosomal Protein HMG-14

1994 • 83 citations

Cloning and structural analysis of cDNA and the gene for mouse transcription factor UBF

1991 • 76 citations

Targeted disruption of the Oct-2 locus in a B cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activation.

1993 • 70 citations

Differential transactivation potential of Oct1 and Oct2 is determined by additional B cell-specific activities.

1994 • 66 citations

Repression of basal transcription by HMG2 is counteracted by TFIIH-associated factors in an ATP-dependent process.

1994 • 64 citations

Oct2 Transactivation from a Remote Enhancer Position Requires a B-Cell-Restricted Activity

1992 • 63 citations

Identification of Ets-like lymphoid specific elements within the immunoglobulin heavy chain 3′ enhancer

1992 • 61 citations

Involvement of a second lymphoid-specific enhancer element in the regulation of immunoglobulin heavy-chain gene expression.

1990 • 54 citations

Activation of Octamer-Containing Promoters by Either Octamer-Binding Transcription Factor 1 (OTF-1) or OTF-2 and Requirement of an Additional B-Cell-Specific Component for Optimal Transcription of Immunoglobulin Promoters

1990 • 41 citations

Functional differences between the Oct2 transactivation domains determine the transactivation potential of individual Oct2 isoforms

1994 • 38 citations

Acetylated HMG1 protein interacts specifically with homologous DNA polymerase alpha in vitro

1988 • 35 citations

Analysis of transcriptional stimulation by recombinant Oct proteins in a cell-free system.

1993 • 29 citations

Use of primer-restriction-end adapters in a novel cDNA cloning strategy

1985 • 26 citations

Repression of Basal Transcription by HMG2 Is Counteracted by TFIIH-Associated Factors in an ATP-Dependent Process

1994 • 25 citations

Involvement of a Second Lymphoid-Specific Enhancer Element in the Regulation of Immunoglobulin Heavy-Chain Gene Expression

1990 • 15 citations

Nucleotide sequence of a mouse cDNA encoding the non-histone chromosomal high mobility group protein-2 (HMG-2)

1992 • 7 citations